Clinical trials: Terminally Ill Patients
Peripherally Inserted Central Catheter, Intravenous Access
Comparison Between Initial Routine PICC and General IV Access in Terminally Ill Cancer Patients
To establish the IV access strategy for terminally ill cancer patients, using comparisons of the safety, efficacy, and patient-perceived satisfaction between the initially routine PICC insertion group (routine PICC group) and…
- Trial name
- NCT03299868
- Testing
- peripherally inserted central catheter (PICC)
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Pusan National University Yangsan Hospital
Constipation, Palliative Care
Effectiveness of Docusate in Preventing/Treating Constipation in Palliative Care Patients
The purpose of this study is to determine if docusate is effective in the treatment of constipation in palliative care patients.
- Trial name
- NCT00902031
- Testing
- Docusate Sodium, Sennoside
- Where
- 3 sites in Canada
- Volunteers
- 70 people
- Sponsor
- University of Alberta
Pain
Marijuana in Combination With Opioids in Palliative and Hospice Patients
Study Objectives: Primary reduction of pain and reduction in overall opioid utilization. Secondary improvement in overall patient well being, weight stabilization with increased appetite, improved oxygen saturation, improvement…
- Trial name
- NCT03233633
- Testing
- Medical Marijuana
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- The Connecticut Hospice Inc.
Fever, Palliative Care
Fever In Palliative Care
The goal of this observational study is to evaluate the frequency and characteristics of fever in terminally ill adult patients admitted to the Infectious Diseases Hospice at Luigi Sacco Hospital in Milan.
- Conditions
- Fever, Palliative Care, Terminal Illness
- Trial name
- NCT07106073
- Testing
- Collection of demographic, anthropometric and clinical data.
- Where
- Italy
- Volunteers
- 145 people
- Sponsor
- Stefania Cheli
Family of Dying Patient in the ICU
A Communication Strategy for Families of Patients Dying in the ICU
Decisions to limit life sustaining treatments are made for most patients dying in the ICU, usually with input from the family. The well-being of the family may be jeopardized by involvement in the decision-making process and…
- Trial name
- NCT00331877
- Testing
- family conference with bereavement information leaflet
- Volunteers
- 136 people
- Sponsor
- Famirea Study Group
Emotional Stress, Psychological Distress
Dignity Therapy for Terminally Ill Patients: A Randomized Controlled Trial
We conducted a randomized, controlled trial of dignity therapy for terminally ill patients with the aim of reducing dignity-related distress and demoralization and improving spiritual well-being.
- Conditions
- Emotional Stress, Psychological Distress, Death, Dignity
- Trial name
- NCT04256239
- Testing
- Dignity Therapy
- Where
- Italy
- Volunteers
- 55 people
- Sponsor
- European University of Rome
Hospice and Palliative Care Nursing, Terminally Ill Patients
The Short-Term and Long-Term Effects of Providing Mechanical Bath in Terminally Ill Patients
Providing mechanical bathing (MB) is a commonly used strategy to maintain cleanness and comfort in patients with terminally illness. However, extra devices, costs, and human resources are required for such service.
- Trial name
- NCT06620146
- Testing
- mechanical bathing
- Where
- Taiwan
- Volunteers
- 245 people
- Sponsor
- National Taiwan University Hospital
End Stage Cancer
An Interactive Advance Care Planning Intervention to Facilitate a Good Death for Cancer Patients
The purpose of this 5-year interventional study is to design, implement, and evaluate the effectiveness of an intervention aimed at facilitating prognosis communication and end-of-life care decision-making to increase the extent…
- Trial name
- NCT01912846
- Testing
- Interactive advance care planning, Attention usual care
- Where
- Taiwan
- Volunteers
- 466 people
- Sponsor
- Chang Gung University
Palliative Care
Dignity Therapy+: A Brief Psychological and Existential Intervention for Dying Patients and Their Families.
Background: There has been significant progress in symptom management, pain relief and improvement of quality of life in patients nearing death by implementing palliative care programs.
- Trial name
- DT-plus (NCT02646527)
- Testing
- Dignity Therapy
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- University of Zurich
Neoplasms, Bereavement
ERANet-LAC CODE: International Care Of the Dying Evaluation
Providing high quality care for dying patients and their families is very important. One way one can assess the care provided is to ask bereaved relatives to complete a questionnaire after their family member has died.
- Conditions
- Neoplasms, Bereavement, Quality of Life
- Trial name
- NCT03566732
- Where
- 20 sites in Argentina, Brazil and 5 more
- Volunteers
- 914 people
- Sponsor
- University of Bergen
Hospital Acquired Condition
Hospice Volunteer Community，Dying Patient Prepare Spirtal Care
Due to the aging population, the cases of elderly disability and death caused by chronic diseases and cancer are also increasing; thus increasing the demand and trend of community palliative care.
- Trial name
- volunteer (NCT06432179)
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Terminal Cancer
Nasal Fentanyl and Buccal Midazolam for Dying Patients
When patients are dying they become unable to take oral medication and if they develop symptoms (e.g. pain or agitation) they need to be given a subcutaneous injection of medication.
- Trial name
- NCT02009306
- Testing
- PecFent and Epistatus, Standard subcutaneous medication, Epistatus Alone
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Gloucestershire Hospitals NHS Foundation Trust
Cancer
Non-invasive Ventilation in Terminally Ill Cancer Patients
The occurrence of acute respiratory failure (ARF) is often seen by oncologists as a terminal phase of the disease, this view being based on studies reporting limited survival at considerable costs in such patients.
- Trial name
- NCT00533143
- Testing
- non invasive ventilation (NIV)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Terminally Ill Patients
Mobile Shared Decision-Making Program for ICU Caregivers
By developing a smart mobile shared decision-making (SDM) model, this study aims to assist family members of critically ill end-stage patients in making appropriate decisions, enhance their decision quality, and evaluate the…
- Trial name
- NCT07469878
- Testing
- Experimental: Mobile technology devices
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- CHIA-HUI MA
Mental Health Issue
Mandala Intervention on Mental Distress in Nurses Working With Terminally Ill Patients
Mandala application intervention of mental distress in nurses working with terminally ill patients
- Trial name
- mandala (NCT05444010)
- Testing
- mandala painting
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Istanbul Sabahattin Zaim University
Communication, Palliative Sedation
REcommened Communication With Sympathy in Terminally Ill Cancer Patients Treated With Palliative Sedation
In terminally ill cancer patients, palliative sedation has been applied to intractable refractory symptoms such as pain, dyspnea, delirium, agitation.
- Trial name
- RESTORE (NCT04642677)
- Testing
- healthcare provider's recommended communication with sympathy and printed paper
- Where
- South Korea
- Volunteers
- 62 people
- Sponsor
- Pusan National University Yangsan Hospital
Nausea, Vomiting
Palonosetron for the Treatment of Nausea and Vomiting in Terminally Ill Patients
The primary objective of this study is to determine the complete response (no vomiting and no need for other medications to treat nausea) in terminally ill patients suffering from nausea and/or vomiting, who are treated with…
- Conditions
- Nausea, Vomiting, Terminally Ill
- Trial name
- HUM21469 (NCT00982995)
- Testing
- Palonosetron
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Michigan Rogel Cancer Center
Pain Intractable, Delirium
Pilot Study Comparing Treatment With Dexmedetomidine to Midazolam for Symptom Control in Advanced Cancer Patients
Cancer patients with very difficult to control symptoms at the Abbotsford (AC) and Fraser Valley (FVC) Cancer Centers are referred and admitted to the Tertiary Palliative Care Units at the Abbotsford Regional Hospital and Cancer…
- Conditions
- Pain Intractable, Delirium, Dyspnea, Nausea
- Trial name
- NCT01687751
- Testing
- Dexmedetomidine, Midazolam
- Where
- Canada
- Sponsor
- Fraser Health
Xerostomia, Salivary Gland Diseases
Efficacy Study of a Ginger and Cardamom Gelatin for Xerostomy in Terminally Ill Patients
Xerostomia or dry mouth is the subjective feeling that there is not enough saliva in your mouth. It's a frequent symptom in terminally ill patients receiving palliative care, reducing their quality of life and comfort.
- Conditions
- Xerostomia, Salivary Gland Diseases, Mouth Diseases
- Trial name
- NCT01915966
- Testing
- Cardamom, ginger and orange juice gelatin, Camomile infusion with lemon juice
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Fundacio Salut i Envelliment UAB
Refractory Pains
Efficiency and Safety of a Procedural Sedation by Propofol on Terminally Ill Patients With Refractory Pain
Relieving symptoms of patients hospitalized in a palliative care unit is a priority. Although they receive appropriate care, they may still experience pain refractory to analgesia or/and to conservative treatment during care…
- Trial name
- PROPOPAL2 (NCT02734511)
- Testing
- sedation with propofol
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice