Clinical trials: Thyroid; Wound
Laryngeal Nerve Injuries, Thyroidectomy
Effectiveness of Intraoperative Neuromonitoring of External Branch of Superior Laryngeal Nerve in Thyroid Surgery
The frequent occurrence of impaired function in the external branch of the superior laryngeal nerves following thyroid surgery is recognized as a prevalent complication leading to a diminished quality of life.
- Conditions
- Laryngeal Nerve Injuries, Thyroidectomy, Voice Change
- Trial name
- NCT06002984
- Testing
- Using Neuromonitoring to find EBSLN
- Where
- South Korea
- Volunteers
- 94 people
- Sponsor
- Seoul National University Hospital
Cancer of Thyroid, Vertebral Fracture
Study of the Prevalence of Osteo-metabolic Complications in Patients With Thyroid Cancer
This is a multicenter retrospective observational study aimed to evaluate the prevalence of osteo-metabolic complications in patients with thyroid cancer.
- Conditions
- Cancer of Thyroid, Vertebral Fracture, Osteoporosis
- Trial name
- NCT06627998
- Testing
- Diagnostic (chest x-ray /DXA)and clinical data collected for clinical practice
- Where
- Italy
- Volunteers
- 82 people
- Sponsor
- IRCCS San Raffaele
Malignant Digestive System Neoplasm, Metastatic Head and Neck Carcinoma
Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord
This phase II clinical trial studies how well thermal ablation and spine stereotactic radiosurgery work in treating patients with cancer that has spread to the spine (spine metastases) and is at risk for compressing the spinal…
- Conditions
- Malignant Digestive System Neoplasm, Metastatic Head and Neck Carcinoma, Metastatic Kidney Carcinoma, Metastatic Malignant Neoplasm in the Spine
- Trial name
- NCT02713269
- Testing
- Computed Tomography, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- M.D. Anderson Cancer Center
Thyroid Disease, Recurrent Laryngeal Nerve Injury
Low-Current Stimulation for Recurrent Laryngeal Nerve Protection During Thyroid Surgery
This single-center prospective randomized interventional study evaluated whether intraoperative low-current stimulation could assist recurrent laryngeal nerve localization and reduce temporary recurrent laryngeal nerve injury…
- Trial name
- NCT07706699
- Testing
- 3 mA low-current stimulation-assisted recurrent laryngeal nerve identification, 5 mA low-current stimulation-assisted recurrent laryngeal nerve identification
- Where
- China
- Volunteers
- 150 people
- Sponsor
- The Second Affiliated Hospital of Kunming Medical University
Stress, Job, PTSD
The Sequestration of Holistic Stress Management Techniques for Adults
This remote study is intended to assist the population with access to cost-effective pastoral counseling for stress management in the workplace and every day life.
- Conditions
- Stress, Job, PTSD, Hypervigilance, Hyperthyroidism
- Trial name
- NCT06098755
- Testing
- Holistic Medicine (HM)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Goddess Zena I. Jones
Thyroid Diseases, Parathyroid Diseases
Ropivacaine Plus Magnesium Sulphate Infiltration
In the domain of endocrine gland surgery, thyroidectomy is the most common procedure. Patients report moderate to severe discomfort postoperatively, which is induced by a variety of mechanisms, the most common of which are…
- Conditions
- Thyroid Diseases, Parathyroid Diseases, Postoperative Pain, Anesthesia, Local
- Trial name
- NCT05294393
- Testing
- Ropivacaine 10%, Ropivacaine 10% plus magnesium sulphate 10mg/kg
- Where
- Greece
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Head and Neck Cancer, Spinal Accessory Nerve Injury
Investigation of Effects of Physiotherapy Interventions on Mechanical Properties of Muscle in Head and Neck Cancer
As the head and neck cancer (HNC) survival rate has increased and therefore, the focus of post-treatments is to improve the quality of patients' life by decreasing the side effects.
- Conditions
- Head and Neck Cancer, Spinal Accessory Nerve Injury, Thyroid Cancer, Scapular Dyskinesis
- Trial name
- NCT05399953
- Testing
- Myofascial Release Technique, Exercise, Scar Tissue Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people
- Sponsor
- Yeditepe University
Thyroid Diseases, Surgical Injury
Feasibility of Neostigmine for Intraoperative Neuromonitoring in Thyroid Surgery
For successful intraoperative neuromonitoring (IONM), adequate reversal of neuromuscular blocking agent is a prerequisite in thyroid surgery with .
- Conditions
- Thyroid Diseases, Surgical Injury, Nerve Monitoring
- Trial name
- NCT04873531
- Testing
- Neostigmine, Normal saline
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Seoul National University Hospital
Thyroid Neoplasms, Thyroid Carcinoma
Influence of Thyroid Hormones on the Woundhealing Process
Main goal of this clinical investigation is to investigate different cytokines in wound fluids of euthyroid vs. hypothyroid patients. As a primary endpoint we want to evaluate if different cytokine levels in euthyroid vs.
- Trial name
- NCT00929318
- Testing
- blood sampling
- Where
- Germany
- Volunteers
- 26 people
- Sponsor
- Hannover Medical School
Stroke, Ischemic, Stroke Hemorrhagic
Exploring Accessible Beauty for Individuals With Upper Extremity Deficits
The purpose of this study is to investigate the accessibility of beauty products for individuals with upper extremity disabilities.
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Stroke (CVA) or TIA, Stroke, Acute
- Trial name
- NCT05945784
- Testing
- Use of Rare Beauty makeup products
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Hypothyroidism; Surgery, Head and Neck Cancer
Wound Complications in Head and Neck Surgery
This is a prospective observational study evaluating wound complications following head and neck surgery. Patients undergoing major head and neck surgery will be included in the study.
- Conditions
- Hypothyroidism; Surgery, Head and Neck Cancer, Wound Heal, Laryngeal Cancer
- Trial name
- NCT03134976
- Testing
- Levothyroxine
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Michigan
Thyroid Diseases, Surgery
NerveTrend vs. NerveAssure in Prevention of Recurrent Laryngeal Nerve Injury During Thyroid Surgery
The aim of this study is to compare two distinct modes of NIM Vital application in thyroid surgery: NerveTrend vs. NerveAssure mode with respect to prevalence of early postoperative RLN injury.
- Conditions
- Thyroid Diseases, Surgery, Recurrent Laryngeal Nerve Injuries
- Trial name
- NCT06289309
- Testing
- Neuromonitoring of the recurrent laryngeal nerves
- Where
- Poland
- Volunteers
- 264 people
- Sponsor
- Marcin Barczynski
Radiation-Induced Neoplasms, Breast+Neoplasm+Radiation+Etiology
Cancer Risk in X-Ray Technologists: Second Survey
Researchers at the National Cancer Institute and the University of Minnesota have followed a nationwide cohort of 146,022 radiologic technologists since 1982 (Boice 1992; Doody 1998; Mohan 2003; Sigurdson 2003).
- Conditions
- Radiation-Induced Neoplasms, Breast+Neoplasm+Radiation+Etiology, Thyroid+Neoplasm+Radiation+Etiology
- Trial name
- NCT00410475
- Where
- United States
- Volunteers
- 146,022 people
- Sponsor
- National Cancer Institute (NCI)
Parotid Neoplasm, Thyroid Neoplasms
Bevonescein to Highlight Nerves in Patients Undergoing Head & Neck Surgery
Bevonescein to Highlight Nerves in Patients Undergoing Head \& Neck Surgery
- Conditions
- Parotid Neoplasm, Thyroid Neoplasms, Head and Neck Neoplasms, Surgery
- Trial name
- NCT04420689
- Testing
- Bevonescein
- Where
- 3 sites in United States
- Volunteers
- 27 people
- Sponsor
- Alume Biosciences, Inc.
Graves Disease, Graves Ophthalmopathy
Liver Function After Intravenous Methylprednisolone Administration
Graves' orbitopathy (GO) is a characterized by orbital soft tissue inflammation and oedema associated with glycosaminoglycan deposition and fibrosis. The most frequent cause is Graves' disease.
- Conditions
- Graves Disease, Graves Ophthalmopathy, Liver Diseases, Liver Failure
- Trial name
- NCT03667157
- Testing
- every week IVMP therapy, very high doses IVMP therapy
- Volunteers
- 68 people
- Sponsor
- Medical University of Warsaw
Hashimoto
Eye Movement Desensitization and Reprocessing on Autoimmune Thyroiditis in Adults
The purpose of this study is to evaluate whether Eye Movement Desensitization and Reprocessing (EMDR) is effective in decreasing the level of autoantibodies of patients with autoimmune thyroiditis.
- Trial name
- NCT04472988
- Testing
- Eye Movement Desensitization and Reprocessing, Treatment as Usual
- Where
- Romania
- Volunteers
- 91 people
- Sponsor
- University of Bucharest
Post-operative Pain
Open Thyroid Surgery With Pillow Versus no Pillow for Better Post-operative Outcomes
Primary: To compare the post-operative pain in patients with neck extension and without neck extension. Secondary: To determine the benefit of neck exposure and peri-operative complications, which include duration of operation…
- Trial name
- NCT01620151
- Testing
- Extended neck with standard support or pillow
- Where
- 2 sites in Hong Kong
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Thyroidectomy
RECURRENT LARYNGEAL INJURY WHILE USING LIGASURE Versus CONVENTIONAL KNOT TYING IN TOTAL THYROIDECTOMY
To compare the frequency of recurrent laryngeal injury during total thyroidectomy when utilizing the LigaSure technique against conventional knot tying.
- Trial name
- NCT07522983
- Testing
- tie and knot, Ligasure
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Gulab Devi Hospital
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Secondary Hypothyroidism
Thyroid Function in Critically Ill Patients With Acute Kidney Injury
The objective of this study was to assess the changes in thyroid hormones and its activity during CRRT in patients with Acute Kidney Injury.
- Trial name
- NCT04767763
- Testing
- Assessment of TSH, fT3, fT4,TRH, TT3, TT4, rT3 in patients with CVVHDF
- Where
- Poland
- Volunteers
- 32 people
- Sponsor
- Medical University of Gdansk