Clinical trials: Thyroid Surgery
Thiamine Deficiency, Congenital Heart Disease
Thiamine Influenced on Substrate Energy Effectiveness in Indonesian Children Undergoing Cardiopulmonary Bypass
This is a randomized, double-blind, controlled trial design. It was conducted with a main purpose of evaluating the effect of thiamine supplementation on serum lactate and lactate-pyruvate ratio after surgery as direct indicators…
- Conditions
- Thiamine Deficiency, Congenital Heart Disease, Cardiopulmonary Bypass
- Trial name
- NCT04453761
- Testing
- Neurobion
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- National Cardiovascular Center Harapan Kita Hospital Indonesia
Adhesion, Thyroidectomy
Anti-adhesive Effect and Safety of "Thermo-sensitive Adhesion Barrier (MEDICLORE)"
One of most important complication of thyroid surgery is adhesion. There are many anti-adhesive materials, but none of them showed significant outcomes.
- Trial name
- NCT03293186
- Testing
- MEDICLORE
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
Thyroid Disease
The Impact of COVID-19 Pandemic on Thyroid Surgery in Italy: Results From a Nation-wide Multicentric Study
Italy has been on the frontline of the COVID-19 pandemic, caused by the coronavirus SARS-CoV-2, the need to focus resources to deal with the pandemic led to a disruption of routine surgical care, as well as activity for oncologic…
- Trial name
- NCT04635813
- Testing
- Thyroidectomy
- Where
- Italy
- Volunteers
- 3,800 people
- Sponsor
- University of Cagliari
Thyroid Neoplasms, Endoscopic Surgery
Dual-port Trans-subclavian Thyroid Endoscopic Surgery
This is a prospective, single-center, open-label, non-randomized controlled real-world study aimed at exploring a novel approach to cavity construction for thyroid endoscopic surgery.
- Trial name
- DTS (NCT06398795)
- Testing
- Dual-port Trans-subclavian Thyroid Endoscopic Surgery (DTS)., Conventional open thyroidectomy (COT)
- Where
- China
- Volunteers
- 300 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Esophageal Motility Disorders
Changes in Esophageal Motility and Swallowing Symptoms After Thyroid Surgery
The pronounced effect of goiter on the esophagus needs further exploration, as the mechanisms by which goiter leads to swallowing difficulties are unknown.
- Trial name
- NCT03100357
- Testing
- Thyroidectomy
- Volunteers
- 39 people
- Sponsor
- University of Southern Denmark
Postoperative Hypoparathyroidism, Postsurgical Hypoparathyroidism
PRESS -PAR: Early Detection and PREvention of Symptomatic postSurgical hypoPARathyroidism After Thyroid Surgery"
This study aims to investigate whether an earlier measurement of parathyroid hormone can reduce the number of patients who develop symptomatic hypoparathyroidism.
- Conditions
- Postoperative Hypoparathyroidism, Postsurgical Hypoparathyroidism, Hypoparathyroidism Post-surgical
- Trial name
- PRESSPAR (NCT07491601)
- Testing
- Active vitamin D, Calcium
- Where
- Germany
- Volunteers
- 336 people
- Sponsor
- Nicolas Schlegel
Post Operative Pain, Nausea and Vomiting, Postoperative
ENDOblock: Bilateral Superficial Cervical Blocks With Local Wound Infiltration in Thyroid Surgery
This is a single center, prospective, double-blinded randomized controlled trial comparing the efficacy of bilateral superficial cervical plexus blocks (BSCPB) with local wound infiltration vs placebo with local wound…
- Conditions
- Post Operative Pain, Nausea and Vomiting, Postoperative, Opioid Use
- Trial name
- NCT05805423
- Testing
- bilateral superficial cervical plexus blocks and local wound infiltration
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Hemodynamic Stability
Efficacy of I/v Nalbuphine v/s Iv Lignocain in Attanuation of Pressor Responseduring Laryngeoscopy and Intubation in Middle Age Patient Planned for Thyroid Surgery
Comparison of I/V nalbuphine versus I/V xylocain in attanuation of pressor response during intubation and laryngeoscopy in patients undergoing for thyroid surgery,selection of better supressor agent minimises the drug repated…
- Trial name
- NCT05298761
- Testing
- Lignocaine
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sheikh Zayed Medical College
Thyroid Gland Carcinoma, Thyroid Cancer
Effect of Polyglycolic Acid Mesh (Neoveil) in Thyroid Cancer Surgery
This study is a randomized controlled study to investigate the effect of "Polyglycolic Acid Mesh Sheet (NeoveilTM)" on the thyroid cancer surgery.
- Conditions
- Thyroid Gland Carcinoma, Thyroid Cancer, Thoracic Duct Leak
- Trial name
- NCT03510143
- Testing
- Neoveil (Polyglycolic Acid Mesh)
- Where
- South Korea
- Volunteers
- 330 people
- Sponsor
- Seoul National University Hospital
Hashimoto Thyroiditis, Goiter
Role of Total Thyroidectomy in Relieving Local Symptoms in Hashimoto's Thyroiditis
This study aims to evaluate the role and effectiveness of total thyroidectomy in relieving compressive and local symptoms (such as dysphagia, dyspnea, and anterior neck pain/discomfort) in patients with Hashimoto's thyroiditis…
- Trial name
- NCT07852026
- Testing
- Total Thyroidectomy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Head and Neck Cancer
Radiofrequency Ablation in Treating Patients Who Are Undergoing Surgery for Thyroid Cancer
RATIONALE: Radiofrequency ablation uses a high-frequency, electric current to kill tumor cells. Ultrasound-guided radiofrequency ablation may be effective treatment for thyroid cancer.
- Trial name
- NCT00103155
- Testing
- conventional surgery, radiofrequency ablation
- Where
- United States
- Sponsor
- University of California, San Francisco
Papillary Thyroid Carcinoma, Central Compartment Neck Dissction
The Role of Prophylactic Central Compartment Neck Dissection in the Management of 2 to 4 cm Papillary Thyroid Carcinoma
Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy and is frequently associated with microscopic central neck lymph node metastases, even in the absence of preoperative clinical evidence of nodal…
- Conditions
- Papillary Thyroid Carcinoma, Central Compartment Neck Dissction, Thyroidectomy, Thyroid Lobectomy
- Trial name
- PRO-COMAND (NCT06899347)
- Testing
- Total Thyroidectomy + Central Compartment Neck Dissection, Thyroid Lobectomy + ipCCND
- Volunteers
- 392 people
- Sponsor
- Leonardo Rossi
Papillary Thyroid Carcinoma
Retro-Auricular Single-Site Endoscopic to Papillary Thyroid Carcinoma
The goal of this non randomized control clinical research study is to compare the cosmetic outcomes and efficiacy of retro-auricular single-site endoscopic thyroid lobectomy and central lymph node dissection against conventional…
- Trial name
- NCT05263141
- Testing
- retro-auricular single-site endoscopic thyroidectomy, traditional open surgery thyroidectomy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Sun Yat-sen University
Thyroid Cancer, Surgery
The Importance of Thymus Anatomy to the Radical Resection of Thyroid Cancer Surgery and the Protection of Parathyroid Function
Thyroid cancer is one of the most common endocrine malignancies. In the past three decades, the incidence rate of thyroid cancer has continued to rise rapidly in many countries and regions around the world.
- Trial name
- NCT06851260
- Testing
- Fine-dissection of the thymus
- Volunteers
- 5 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Thyroid Nodule
2-day Prophylactic Antibiotic is Effective in Transoral Endoscopic Thyroidectomy
In transoral thyroidectomy via vestibular approach (TOETVA), prophylactic antibiotic for 5~7 days is recommended for the clean-contaminated wound.
- Trial name
- NCT04268407
- Testing
- Amoxicillin Clavulanate
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Thyroid Surgery
Comparison of Bupivacaine Wound Infiltration Versus Wound Instillation to Minimize Postoperative Pain After Thyroid Surgery
Pain management following thyroidectomies, which can cause mild to moderate postoperative pain, particularly in the first 24 hours following surgery, has received little attention .
- Trial name
- NCT06789575
- Testing
- Bupivacaine, Adrenaline, Lidocaine (drug)
- Volunteers
- 102 people
- Sponsor
- Assiut University
Sore Throat, Tracheal Tubes With an Inner Diameter of 6.0mm
Different Models of Tracheal Catheters Are Used for Female Thyroid Glands
Objective:Compare whether the use of tracheal catheters of models 6.0 and 6.5 causes less sore throat in women after thyroid surgery compared with the traditional use of model 7.0 tracheal catheters.Methods: Investigators…
- Conditions
- Sore Throat, Tracheal Tubes With an Inner Diameter of 6.0mm, Tracheal Tubes With an Inner Diameter of 6.5mm, Tracheal Tubes With an Inner Diameter of 7.0mm
- Trial name
- NCT06967896
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Anqing Municipal Hospital
Primary Hyperparathyroidism
Near Infrared Fluorescent Imaging in Thyroid and Parathyroid Surgery With the Fluobeam(TM) System of Fluoptics
Hypothesis: Intraoperative use of near infrared fluorescent imaging technology and detection of Methylene Blue fluorescence will improve outcomes following thyroid and parathyroid surgery.
- Trial name
- NCT01598727
- Testing
- Fluobeam(TM) Imaging System (Fluoptics)
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Colorectal Cancer, Head and Neck Cancer
Boronophenylalanine-Fructose Complex (BPA-F) and/or Sodium Borocaptate (BSH) Followed By Surgery in Treating Patients With Thyroid Cancer, Head and Neck Cancer, or Liver Metastases
RATIONALE: Diagnostic procedures using boronophenylalanine-fructose complex (BPA-F) and/or sodium borocaptate (BSH) to detect the presence of boron in tumor cells may help determine whether patients who have thyroid cancer, head…
- Conditions
- Colorectal Cancer, Head and Neck Cancer, Metastatic Cancer
- Trial name
- NCT00062348
- Testing
- boronophenylalanine-fructose complex, sodium borocaptate, conventional surgery
- Where
- Germany
- Volunteers
- 27 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Thyroid Cancer, Thyroid and Parathyroid Surgery
The Effect of Head Position on the Optik Nerve Sheath Diameter in Patients During Thyroid Surgery
THE EFFECT OF HEAD POSİTİON ON THE OPTİC NERVE SHEATH DİAMETER İN PATİENTS DURİNG THYROİD SURGERY
- Conditions
- Thyroid Cancer, Thyroid and Parathyroid Surgery, Thyroid Adenoma
- Trial name
- NCT07298187
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa