Clinical trials: Thyroidectomy
Safety and Cosmetic Issues in Endoscopic Thyroidectomy
Evaluation of Endoscopic Thyroidectomy Via Axillo-breast Approach in Thyroid Nodules
Evaluation of Endoscopic Thyroidectomy via Axillo-breast Approach in Thyroid Nodules regarding safety and cosmetic outcomes
- Trial name
- Thyroidectomy (NCT04329455)
- Testing
- Endoscopic thyroidectomy
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Thyroidectomy, Oxidative Stress
Opioid-Free Versus Opioid-Based Anesthesia in Thyroid Surgery
This study will compare opioid-free anesthesia and opioid-based anesthesia in adult euthyroid patients undergoing elective thyroidectomy.
- Conditions
- Thyroidectomy, Oxidative Stress, Anesthesia
- Trial name
- OFA-OBA (NCT07864155)
- Testing
- Fentanyl (IV), Dexmedetomidine and lidocaine
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Malatya Egitim Ve Arastirma Hastanesi
Hypocalcemia
Preoperative Vitamin D for Post-thyroidectomy Hypocalcemia
The purpose of this study is to determine if pre-operative vitamin D supplementation lowers the incidence of post-operative transient or permanent hypoparathyroidism in patients undergoing total thyroidectomy.
- Trial name
- NCT01609439
- Testing
- Vitamin D
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alberta
Thyroid Diseases, Parathyroid Diseases
Ropivacaine Plus Magnesium Sulphate Infiltration
In the domain of endocrine gland surgery, thyroidectomy is the most common procedure. Patients report moderate to severe discomfort postoperatively, which is induced by a variety of mechanisms, the most common of which are…
- Conditions
- Thyroid Diseases, Parathyroid Diseases, Postoperative Pain, Anesthesia, Local
- Trial name
- NCT05294393
- Testing
- Ropivacaine 10%, Ropivacaine 10% plus magnesium sulphate 10mg/kg
- Where
- Greece
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Permanent Hypoparathyroidism
Quality in Patients With Permanent Hypoparathyroidism After Total Thyroidectomy
Quality of life study. The study with include all patients operated with total thyroidectomy between 2005-2015 in Uppsala-Örebro healthcare region, Sweden.
- Trial name
- NCT04998968
- Where
- Sweden
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Hypocalcemia
Prophylactic Infusion of Calcium Gluconate Reducing the Rate of Hypocalcaemia After Total Thyroidectomy
Post-total thyroidectomy hypocalcaemia is a common complication with the rate ranging from 13-49% in a meta-analysis. However, the rate in UMMC in 2018 and 2019 were 40% and 23% respectively.
- Trial name
- NCT04491357
- Testing
- Calcium Gluconate, Normal saline
- Where
- Malaysia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Postoperative Pain
Comparison of Two Drugs Bupivacaine and Ropivacaine for Postoperative Analgesia in Bilateral Superficial Cervical Plexus Block After Thyroidectomy
There is significant difference between bupivacaine and ropivacaine in terms of postoperative pain assessment in patients undergoing total thyroidectomy with bilateral superficial cervical plexus block.
- Trial name
- NCT07779551
- Testing
- Group 1 will receive 10ml of 0.25% bupivacaine, Group 2 will receive 10ml of 0.25% ropivacaine on each side.
- Where
- Pakistan
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Sargodha Medical College
Anesthesia, Airway Complication of Anesthesia
Dexmedetomidine Versus Lidocaine in Attenuating Airway Reflexes During Recovery of Thyroidectomy Patients
It is widely believed that most of the patients experience a cough upon emergence from general anesthesia, due to many causes including the presence of an endotracheal tube, uncleared secretions and anesthetic gas.
- Trial name
- NCT05657028
- Testing
- Dexmedetomidine, Lidocaine IV
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Throid Surgery, Airway Complication of Anaesthesia
Comparison of the Effects of Total Intravenous Anaesthesia With Target-Controlled Infusion (TCI) and Inhalation Anaesthesia on Airway Complications During Extubation and in the Early Postoperative Period in Thyroidectomy Surgery
Thyroid surgery is one of the most complex operations in the head and neck region due to its close relationship with anatomical structures and the high risk of recurrent laryngeal nerve injury.
- Conditions
- Throid Surgery, Airway Complication of Anaesthesia, Coughing Responses at Tracheal Extubation, Laryngospasm on Emergence
- Trial name
- NCT07325669
- Testing
- tıva
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- dilara gocmen
Thyroid Diseases
Systematic Administration of Calcium and Vitamin D After Thyroidectomy
Transient hypocalcaemia consist the most common postoperative complication after thyroidectomy (10-45%). It may be mild and subclinical or cause mild or severe symptoms and may lead to longer hospital stay as well as in…
- Trial name
- NCT03777033
- Testing
- Prophylactic protocol with Ca and Vit D
- Where
- Greece
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Hellenic Red Cross Hospital
Intubation; Difficult or Failed, Airway Complication of Anesthesia
Neural Integrity Monitor Electromyogram (NIM-EMG) Endotracheal Tube Intubation With Video Laryngoscope
Laryngeal nerve monitoring is performed to prevent intraoperative nerve damage in thyroidectomy operations. NIM-EMG intubation tube is used while monitoring the recurrent laryngeal nerve.
- Conditions
- Intubation; Difficult or Failed, Airway Complication of Anesthesia, Pain, Postoperative, Anesthesia Intubation Complication
- Trial name
- NCT05366582
- Testing
- Macintosh Laryngoscope, Video Laryngoscope
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Post Operative Pain, Nausea and Vomiting, Postoperative
ENDOblock: Bilateral Superficial Cervical Blocks With Local Wound Infiltration in Thyroid Surgery
This is a single center, prospective, double-blinded randomized controlled trial comparing the efficacy of bilateral superficial cervical plexus blocks (BSCPB) with local wound infiltration vs placebo with local wound…
- Conditions
- Post Operative Pain, Nausea and Vomiting, Postoperative, Opioid Use
- Trial name
- NCT05805423
- Testing
- bilateral superficial cervical plexus blocks and local wound infiltration
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Drug Compliance, Patient Acceptance of Health Care
Effect of Mobile Application Usage on Drug Compliance After Thyroidectomy
In patients who have undergone thyroidectomy surgery, drug use will be reminded with a mobile application in the postoperative period.
- Trial name
- NCT05503576
- Testing
- reminder mobile application
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Goiter, Hypothyroidism
ThyrOp: A Study of Individual Subclinical Hypothyroidism After Hemithyroidectomy for Benign Nontoxic Goiter
The hypothesis of the study is that among patients that do not develop overt hypothyroidism after hemithyroidectomy, weight gain is a clinical manifestation of a postoperatively lowered set point of thyroid function - even if the…
- Conditions
- Goiter, Hypothyroidism, Weight Gain
- Trial name
- ThyrOp (NCT01358136)
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Naestved Hospital
Thyroid
Thyroid Autotransplantation in Quadriceps Femoris Muscle
providing an almost natural ectopic thyroid in patients undergoing total thyroidectomy, remains a challenging subject that can benefits patients with a non-pharmacological substitute for their normal gland.
- Trial name
- NCT04684953
- Testing
- Throid autotransplantation, Hormone
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
The Role of Valsalva Manoeuvre, in Thyroidectomy to Reduce Postoperative Bleeding
Valsalva Maneuver in Thyroidectomy
Bleeding after total thyroidectomy remains a rare event that affects early postoperative morbidity, occurring in 0.3% up to 4.2% of cases.
- Trial name
- NCT05474261
- Testing
- Valsalva maneuver
- Where
- Italy
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Time Taken for Identification of Single Recurrent Laryngeal Nerve, Intra-operative Blood Loss
Comparison Between Two Techniques During Thyroidectomy (Conventional Dissection Technique and Injection of Methylene Blue Dye Into Inferior Thyroid Artery Technique) Regarding Recurrent Laryngeal Nerve Identification and Preservation
The aim of the study is to evaluate the value of injection of methylene blue dye into the inferior thyroid artery for the help of the identification and dissection of recurrent laryngeal nerve, so thyroidectomy could be done with…
- Trial name
- RLN (NCT07067814)
- Testing
- Methylene blue group
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Thyroid Cancer, Regret
Regret Emotion After Thyroidectomy in Low-Risk Papillary Thyroid Cancer
This randomized, active-controlled, non-inferiority trial is scheduled to begin in May 2025 and will continue until June 2027. Inclusion criteria: (1) Patients with low-risk papillary thyroid cancer without lymph node metastasis…
- Trial name
- NCT06804863
- Testing
- Postoperative Regret Reduction through Immediate Quality of Life Intervention
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Ligature; Hemorrhage, Recurrent Laryngeal Nerve Injuries
Comparison of Liagure Safety in Thyroidectomy With Conventional Thyroidectomy
To compare intraoperative and postoperative complication rates in thyroidectomy between ligasure and traditional vascular ligation and clipping .
- Conditions
- Ligature; Hemorrhage, Recurrent Laryngeal Nerve Injuries, Hypocalcemia
- Trial name
- NCT05684536
- Testing
- liagsure device
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Imam Mohammad ibn Saud Islamic University
Thyroid
The Efficacy and Safety of Thunderbeat in Thyroid Surgery
The aim of this study is to compare the results of total thyroidectomy using the Thunderbeat device to that with the harmonic scalpel.
- Trial name
- Thunderbeat (NCT02304172)
- Testing
- Thunderbeat (Group A), Harmonic (Group B)
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital