Clinical trials: Tic Douloureux
Trigeminal Neuralgia
Comparison Between Magnetic Field and Laser Therapy in Management of Trigeminal Neuralgia
Trigeminal neuralgia (TN) was defined by The International Association for the Study of Pain (IASP) as severe, sudden, usually unilateral, stabbing, brief, recurrent attacks of pain in one or more distributional branches of the…
- Trial name
- NCT05075707
- Testing
- Electromagnetic therapy., Low level laser therapy (LLLT)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Delta University for Science and Technology
Trigeminal Neuralgia, Microvascular Decompression Surgery
Assessment in Patients With Essential Trigeminal Neuralgia of Nerve Involvement by MRI in DTI and Functional Connectivity in "Resting State"
Essential trigeminal neuralgia is the most common facial pain. In forms resistant to drug and disabling treatments, surgical treatment may be offered to the patient.
- Conditions
- Trigeminal Neuralgia, Microvascular Decompression Surgery, Diffusion Tensor Imaging
- Trial name
- SENSE (NCT05051072)
- Testing
- Assessment of the trigeminal nerve by diffusion tensor MRI and in "resting state" in the context of essential neuralgia
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Idiopathic Trigeminal Neuralgia
High-voltage Pulsed Radiofrequency on Gasserian Ganglion to Treat Patients With Primary Trigeminal Neuralgia
The study is designed to compare the effectiveness and safety of high-voltage Pulsed radiofrequency and nerve block for the treatment of primary Trigeminal Neuralgia patients with ineffective conservative treatment and explore…
- Trial name
- NCT03131466
- Testing
- High-voltage pulsed radiofrequency, Nerve block
- Where
- 3 sites in China
- Volunteers
- 134 people
- Sponsor
- Beijing Tiantan Hospital
Trigeminal Neuralgia
Efficacy of Guanfacine and Lidocaine Combination in Trigeminal Nerve Block for Pain Management in Trigeminal Neuropathy
A phenome-wide association study (PheWAS) identified an association between a loss of function variant in the human alpha 2B adrenergic receptor gene and trigeminal nerve disorders.
- Trial name
- NCT03865940
- Testing
- Lidocaine, Guanfacine
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Vanderbilt University Medical Center
Trigeminal Neuralgia
Observational Study on the Treatment of Trigeminal Neuralgia by Radiosurgery
This study aims to evaluate the outcome of patient treated by radiosurgery on LINAC with high dose rate for classical trigeminal neuralgia
- Trial name
- NATURE (NCT05677243)
- Where
- Monaco
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Princesse Grace
Trigeminal Neuralgia, Refractory Pain
Fluoroscopic-Guided Bipolar Versus Monopolar Pulsed Radiofrequency for Refractory Trigeminal Neuralgia
A prospective exploratory study aiming at comparing pulsed bipolar versus pulsed unipolar radiofrequency ablation in patients with medically refractory trigeminal neuralgia.
- Trial name
- NCT06779578
- Testing
- Bipolar pulsed radiofrequency, Mopolar pulsed radiofrequency
- Where
- 2 sites in Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University
Trigeminal Neuralgia (TN), Other Neuropathic Pain
New Formulation and Food Effect Study of BIIB074
The primary objectives of the study are to assess the relative bioavailability of the BIIB074 direct compression formulation (DCF) to the BIIB074 roller compaction formulation (RCF) and to determine the effect of a high-fat meal…
- Trial name
- NCT02951221
- Testing
- BIIB074 Treatment A, BIIB074 Treatment B, BIIB074 Treatment C
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Biogen
Trigeminal Neuralgia, Tic Douloureux
Surface Acoustic Wave Ultrasound in Trigeminal Neuralgia Pain
The "Suicide Disease", Trigeminal Neuralgia (TN) is arguably caused by one of the most discrete and eloquently reversible central nervous system lesions known to the field of neurology. Recently Dr Adahan H. and Dr Binshtok A.
- Trial name
- NCT01447108
- Testing
- Low Intensity Low Frequency Surface Acoustic Wave Ultrasound (PainShield™)
- Where
- Israel
- Volunteers
- 16 people
- Sponsor
- Sheba Medical Center
Trigeminal Neuralgia
A Nasal Applicator for the Treatment of Trigeminal Neuralgia
The pain from Trigeminal Neuralgia (TN) imposes a substantial burden on patients in daily function and reduces quality of life. The sphenopalatine ganglion, located in the posterior part of the middle nasal turbinate, is involved…
- Trial name
- NCT01761604
- Testing
- Nasal ganglion block for TN
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Chicago Anesthesia Pain Specialists
Atypical Facial Pain, Persistent Idiopathic Facial Pain
Efficacy and Safety of ATNC05 in Treatment of Atypical Facial Pain
The purpose of the study is to test the efficacy of ATNC05 in the treatment of Atypical Facial Pain (AFP), also known as Persistent Idiopathic Facial Pain (PIFP).
- Conditions
- Atypical Facial Pain, Persistent Idiopathic Facial Pain, Atypical Trigeminal Neuralgia, Neuropathic Orofacial Pain
- Trial name
- AFP (NCT01920087)
- Testing
- ATNC05
- Where
- United States
- Sponsor
- Allodynic Therapeutics, Inc
Trigeminal Neuralgia (TN)
Developing a Clinical Prediction Model for Adverse Outcomes in Percutaneous Trigeminal Ganglion Balloon Compression
This clinical study aims to investigate adverse outcomes following percutaneous balloon compression (PBC) of the trigeminal ganglion, establish a predictive model, and assess the probability of postoperative complications.The…
- Trial name
- NCT06998420
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Affiliated Hospital of Nantong University
Trigeminal Neuralgia
Comparative Study inTreatment of Trigeminal Neuralgia
This study aims to evaluate the results of percutaneous radiofrequency rhizotomy and the effectiveness of microvascular decompression for the treatment of trigeminal neuralgia and Comparing between them according the different…
- Trial name
- NCT04801407
- Testing
- percutaneous radiofrequency trigeminal rhizotomy, Microvascular decompression of the trigeminal nerve
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sohag University
Trigeminal Neuralgia (TN)
Ultra-Early Gamma Knife Stereotactic Radiosurgery for TN
The goal of this clinical trial is to evaluate Gamma Knife stereotactic radiosurgery (GK-SRS) as an ultra-early treatment option for trigeminal neuralgia (TN). The main questions it aims to answer are: 1.
- Trial name
- URGEnt-TN (NCT06949436)
- Testing
- GK SRS
- Where
- 2 sites in Canada
- Volunteers
- 80 people
- Sponsor
- University of Alberta
Trigeminal Neuralgia
Oxtellar Extended Release (Oxcarbazepine Extended Release) Patients With Trigeminal Neuralgia
To evaluate the affect Oxtellar XR (Extended Release) has on neurology patients with trigeminal neuralgia (TN), and if it impacts their quality of life.
- Trial name
- NCT03374709
- Testing
- Oxtellar XR 150Mg Extended Release Tablet
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Trigeminal Neuralgia, Blood
Transcriptome Sequencing Analysis of Whole Blood From Patients With Trigeminal Neuralgia
Trigeminal neuralgia is a type of neuropathic pain that brings great physical and psychological pressure to patients. Chronic pain can cause changes in the composition of central and peripheral body fluids, and these changes may…
- Conditions
- Trigeminal Neuralgia, Blood, Plasma, Cerebrospinal Fluid
- Trial name
- NCT04923399
- Volunteers
- 20 people
- Sponsor
- Peking University People's Hospital
Trigeminal Neuralgia
Comparing Clinical Benefits of Gamma Knife and Microvascular Decompression for Trigeminal Neuralgia
Clinical randomized study to compare the clinical effectiveness between two modalities of treatment of trigeminal neuralgia namely gamma knife radio surgery and microvascular decompression
- Trial name
- NCT03991039
- Testing
- Gamma knife
- Volunteers
- 84 people
- Sponsor
- University of Baghdad
Trigeminal Neuralgia
Comparision Efficacy of Carbamazepine & Oxcarbazepine in the Treatment of Trigeminal Neuralgia- a Randomised Clinical Trial
Trigeminal neuralgia is a neuropathic facial pain condition, characterized by unilateral paroxysmal pain which can be described as stabbing or electric shock like, in the distribution of one or more divisions of trigeminal nerve…
- Trial name
- NCT04996199
- Testing
- Oxcarbazepine, Carbamazepine
- Where
- 2 sites in India
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Trigeminal Neuralgia, Multiple Sclerosis
Symptomatic Trigeminal Neuralgia Attributed to Multiple Sclerosis - a Prospective Study in 60 Patients
Clinical characteristics, neuroanatomical findings and efficacy of medical and surgical treatment of symptomatic trigeminal neuralgia - a systematic prospective study of 60 consecutive patients
- Conditions
- Trigeminal Neuralgia, Multiple Sclerosis, Pain, Neuropathic
- Trial name
- NCT04371575
- Testing
- Carbamazepine
- Volunteers
- 60 people
- Sponsor
- Stine Maarbjerg, MD PhD
Trigeminal Neuralgia, Rhizotomy
Trigeminal Evoked Responses to Improve Rhizotomy
Trigeminal neuralgia (TGN) is a debilitating pain syndrome where electrical, shock- like jolts of pain affect the face. Trigeminal somatosensory evoked potentials (TSEPs) provide a promising modality for measuring the trigeminal…
- Trial name
- NCT05738096
- Testing
- TSEP + rhizotomy surgery, TSEPs recording only
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Trigeminal Neuralgia, Trigeminal Neuralgia, Idiopathic
CT-guided vs Fluoroscopy-guided Trigeminal Ganglion Radiofrequency Thermocoagulation for Idiopathic Trigeminal Neuralgia
The goal of this clinical trial is to compare the effectiveness and safety of CT-guided versus fluoroscopy-guided trigeminal ganglion radiofrequency thermocoagulation (TG-RFT) in treating idiopathic trigeminal neuralgia (TN) in…
- Trial name
- NCT06620172
- Testing
- CT-guided Radiofrequency Thermocoagulation (RFT), Fluoroscopy-guided Radiofrequency Thermocoagulation (RFT)
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Zagazig University