Clinical trials: Tomography, X-Ray Computed
Cancer
Adult and Paediatric Patient Radiation Doses From Multidetector Row Computed Tomography Scans: a National Survey
The situation in Italy regarding radiation dose to patients undergoing Multidetector row Computed Tomography (MDCT) scans is unclear despite Italian law require that each centre check the Reference Dose Level (RDL) every two…
- Trial name
- MDCTDOSE (NCT01436006)
- Where
- Italy
- Volunteers
- 6,700 people
- Sponsor
- University of Palermo
Computed Tomography, Diagnostic Imaging
Ultravist: Safety and Efficacy in Computed Tomography of Head and Body
This is a research study involving the use of a contrast agent called Ultravist Injection. Ultravist, the study drug, is used to improve the pictures obtained using computed tomography (CT).
- Trial name
- NCT00244140
- Testing
- Iopromide 370 mg I/mL, Iopromide 300 mg I/mL
- Where
- 23 sites in United States, Colombia and 2 more
- Volunteers
- 435 people
- Sponsor
- Bayer
Computed Tomography, Radiation Dosage
Breast Displacement and CT Radiation Dose
The primary hypothesis of this study is that breast displacement out of the direct plane of imaging during computed tomography (CT) of the abdomen will reduce effective radiation dose to the female breast.
- Trial name
- Chrysalis (NCT01261559)
- Testing
- Chrysalis breast displacement device
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Washington
Ischemic Stroke
Clinical Mismatch in the Triage of Wake Up and Late Presenting Strokes Undergoing Neurointervention With Trevo
The purpose of the study is to evaluate the hypothesis that Trevo thrombectomy plus medical management leads to superior clinical outcomes at 90 days as compared to medical management alone in appropriately selected subjects…
- Trial name
- DAWN (NCT02142283)
- Testing
- Trevo Thrombectomy Procedure, Medical Management
- Where
- 32 sites in United States, Australia and 3 more
- Volunteers
- 206 people
- Sponsor
- Stryker Neurovascular
Coronary Artery Disease
A Phase 3 Multi-center Study to Assess PET Imaging of Flurpiridaz F 18 Injection in Patients With CAD.
The primary objective of the study is to assess the diagnostic efficacy (specificity and sensitivity) of flurpiridaz F18 injection PET myocardial perfusion imaging (MPI) compared to single photon emission computed tomography…
- Trial name
- NCT01347710
- Testing
- Flurpiridaz F18, 99mTechnicium (sestamibi or tetrofosmin)
- Where
- 81 sites in United States, Canada and 2 more
- Volunteers
- 795 people
- Sponsor
- Lantheus Medical Imaging
Metastatic Cancer, Unspecified Adult Solid Tumor, Protocol Specific
PET Scan and CT Scan in Evaluating Response in Patients Undergoing Radiofrequency Ablation for Lung Metastases
RATIONALE: Radiofrequency ablation uses a high-frequency, electric current to kill tumor cells. Diagnostic procedures, such as PET scan and CT scan, may help doctors measure the patient's response to treatment.
- Trial name
- TEPARF (NCT00382252)
- Testing
- computed tomography, positron emission tomography, radiofrequency ablation
- Where
- 3 sites in France
- Volunteers
- 89 people
- Sponsor
- Institut Bergonié
Dental Diseases
Dual Energy Cone-Beam Computed Tomography (DE-CBCT) Assessment of Jaw Bone Density
Current radiologic imaging modalities used in dentistry provide information on the morphology of the hard tissues. Additional information on the density of bone has practical relevance, for example, in dental implant treatment…
- Trial name
- NCT04686084
- Testing
- Dual-energy computed tomography scan
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of California, Los Angeles
Ultrasound, CT Scans
Open-Label, Safety Study Evaluating the Use of Dexmedetomidine in Pediatric Subjects Undergoing Procedure-Type Sedation
The objective of this study is to evaluate the safety of dexmedetomidine in a pediatric population requiring non-intubated, spontaneous breathing, moderate to deep sedation (NI-MDS) for elective diagnostic or therapeutic…
- Conditions
- Ultrasound, CT Scans, MRIs
- Trial name
- NCT01519167
- Testing
- Dexmedetomidine, Midazolam, Fentanyl
- Where
- 11 sites in United States, Puerto Rico
- Volunteers
- 91 people
- Sponsor
- Hospira, now a wholly owned subsidiary of Pfizer
Stage III Lung Non-Small Cell Cancer AJCC v7, Stage IIIA Lung Non-Small Cell Cancer AJCC v7
Positron Emission Tomography and Computed Tomography in Guiding Radiation Therapy for Stage III Non-small Cell Lung Cancer
This randomized phase II trial studies how well positron emission tomography (PET)/computed tomography (CT)-guided radiation therapy works compared to standard radiation therapy in treating patients with stage III non-small cell…
- Conditions
- Stage III Lung Non-Small Cell Cancer AJCC v7, Stage IIIA Lung Non-Small Cell Cancer AJCC v7, Stage IIIB Lung Non-Small Cell Cancer AJCC v7
- Trial name
- NCT01507428
- Testing
- 18F-Fluoromisonidazole, Carboplatin, Computed Tomography
- Where
- 31 sites in United States, Canada
- Volunteers
- 138 people
- Sponsor
- National Cancer Institute (NCI)
Myocardial Infarction, Coronary Artery Disease
PET/CT Study in the Diagnosis of Coronary Plaque
This study is being done to determine if a picture taking test of the heart, positron emission tomography/computed tomography (or cardiac PET/CT), can identify the blockages in the heart arteries that lead to heart attacks when…
- Conditions
- Myocardial Infarction, Coronary Artery Disease, Cardiac Catheterization
- Trial name
- PET/CT (NCT00850473)
- Testing
- PET/CT
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Washington University School of Medicine
Diagnostic Imaging
A Clinical Study of Xenetix 300 in Multislice Computed Tomography (CT) Pediatric Indications
This is a clinical study of Xenetix 300 in Multislice Computed Tomography (MSCT) in pediatric indications.
- Trial name
- NCT00347022
- Testing
- Xenetix, Visipaque
- Where
- France
- Volunteers
- 145 people
- Sponsor
- Guerbet
Coronary Artery Disease
Comparison of DSCT With IB-IVUS and Angiography in the Assessment of Coronary Artery Disease
The purpose of this study is to compare different methods of looking at atherosclerotic plaques in heart arteries. Identifying the characteristics of these plaques noninvasively would be very valuable.
- Trial name
- NCT00622167
- Testing
- Integrated Backscatter IVUS, Dual Source Computed Tomography
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Massachusetts General Hospital
Chest Pain, Acute Coronary Syndrome
Computed Tomography Coronary Angiogram (CTCA) Versus Traditional Care in Emergency Department Assessment of Potential Acute Coronary Syndromes (ACS)
This multi-center, randomized, controlled trial conducted in Emergency Departments (ED) compares computed tomography (CT) coronary angiography with the traditional approach (usual care) for low- to intermediate-risk chest pain…
- Conditions
- Chest Pain, Acute Coronary Syndrome, Acute Myocardial Infarction, Coronary Artery Disease
- Trial name
- NCT00933400
- Testing
- CT Coronary Angiography (CTCA), Traditional Strategy
- Where
- 5 sites in United States
- Volunteers
- 1,392 people
- Sponsor
- American College of Radiology
Esophageal Cancer
FLT PET/CT for Staging, Target Definition and Assessment of Response to Therapy in Patients With Esophageal Cancer
The purpose of this pilot study is to develop a more advanced software program that will collect, compare and analyze tumor images for evaluation.
- Trial name
- NCT01243619
- Testing
- 3'-deoxy-3'-(18) F-fluorothymidine
- Where
- 3 sites in United States
- Volunteers
- 5 people
- Sponsor
- Dana-Farber Cancer Institute
Spinal Fractures
Study to Investigate the Long Term Survivorship of Coflex
Examine the long-term survivorship via CT Scan of the coflex in patients who presented with spinous process fracture(s) at 24 months in the Paradigm Spine coflex IDE Study.
- Trial name
- NCT02918669
- Testing
- CT Scan
- Volunteers
- 12 people
- Sponsor
- Paradigm Spine
Parkinsonian Syndrome, Parkinson Disease(PD)
A Study to Evaluate the Diagnostic Efficacy of DaTSCAN™ Ioflupane (123I) Injection in Single Photon Emission Computed Tomography (SPECT) for the Diagnosis of Parkinsonian Syndrome (PS) in Chinese Patients
This is a multicenter, open-label, non-controlled, non-randomized, phase 3 clinical study to compare the SPECT findings after a single IV administration of DaTSCAN™ ioflupane (123I) injection for patients with a clinical…
- Conditions
- Parkinsonian Syndrome, Parkinson Disease(PD), Multiple System Atrophy (MSA), Progressive Supranuclear Palsy (PSP)
- Trial name
- NCT04193527
- Testing
- DaTSCAN™ Ioflupane (123I) Injection
- Where
- 10 sites in China
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Cystinuria, Nephrolithiasis, Calcium Oxalate
Use of an Herbal Preparation to Prevent and Dissolve Kidney Stones
We will investigate the safety and effectiveness of a mixture of 9 east Indian herbs known as Cystone regarding their ability to dissolve existing kidney stones and prevent formation of new ones.
- Trial name
- NCT00381849
- Testing
- Cystone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Neuroendocrine Tumors
Theranostics of Radiolabeled Somatostatin Antagonists 68Ga-DOTA-JR11 and 177Lu-DOTA-JR11 in Patients With Neuroendocrine Tumors
This study has 3 steps and not everyone will have all 3 steps done. The overall goals are to see if a new experimental drug is safe to image (step 1) and treat neuroendocrine tumors (step 2 and 3).
- Trial name
- NCT02609737
- Testing
- PET/CT Imaging, 68Ga-DOTA-JR11, 177Lu-DOTA-JR11
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Kidney Failure, Chronic, Kidney Failure, Acute
Sodium Chloride and Contrast Nephropathy
This phase II, open, non-inferiority, randomized and controlled clinical trial is aimed to ascertain the incidence of contrast nephropathy in outpatients undergoing CT scan with contrast.
- Conditions
- Kidney Failure, Chronic, Kidney Failure, Acute, Heart Failure, Diabetes
- Trial name
- PNIC-Na (NCT03476460)
- Testing
- Oral sodium chloride, Intravenous sodium chloride
- Where
- Spain
- Volunteers
- 271 people
- Sponsor
- Hospital Universitario Ramon y Cajal
Radiocontrast Nephropathy
N-Acetylcysteine to Prevent Radiocontrast Nephropathy in Emergency Department Patients
Multiple agents have been studied to prevent radiocontrast nephropathy. One of these agents is N-Acetylcysteine. Previous trials to assess N-Acetylcysteine's efficacy in the prevention of contrast nephropathy have been promising.
- Trial name
- NCT00780962
- Testing
- N-Acetylcysteine (NAC), 0.9% Sodium-chloride
- Where
- United States
- Volunteers
- 399 people
- Sponsor
- Beth Israel Deaconess Medical Center