Clinical trials: Tooth, Impacted
Third Molars Extraction, Low Level Laser Therapy
Effects of Low-level Laser Therapy on Soft and Hard Tissue Healing After Impacted Mandibular Third Molar Extraction
Impacted lower third molar extraction is one of the most commonly performed dental procedures in daily practice. However, this is considered a relatively invasive procedure.
- Conditions
- Third Molars Extraction, Low Level Laser Therapy, Bone Healing
- Trial name
- NCT07190950
- Testing
- Low Level Laser Therapy
- Where
- Vietnam
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Pain, Postoperative
Reducing Opioid Use and Misuse After Wisdom Molar Extractions
Reducing opioid prescription related use and misuse is a major focus for countering the national epidemic of opioid overdose and death.
- Trial name
- NCT04414917
- Testing
- Twin block, iPill dispenser
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Impacted Third Molar Tooth
Dexamethasone Effect on Pain and Edema Following Mandibular 3rd Molar Surgery; Pre-operatively vs Post-operatively
TThis is a comparative clinical study which will be conducted in OMFS department of DIKIOHS, DUHS Ojha Karachi. In this study the investigators will be comparing the effect of dexamethasone on pain and edema when administered…
- Trial name
- NCT04319978
- Testing
- Dexamethasone injection
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Tooth, Impacted
Piezoelectric Vibrations and Tissue, Cellular and Molecular Mechanisms of Oral Wound Healing After Third Molar Surgery
The aim of this clinical trial is to investigate and compare the effect of piezoelectric surgery on tissue, cellular and molecular level of oral surgical wound healing and postoperative outcomes (pain, swelling, trismus) after…
- Trial name
- NCT02942108
- Testing
- piezo surgery, conventional surgery
- Where
- Serbia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Impacted Mandibular Third Molar, Wound Healing
Adjacent Molar Outcomes After Third Molar Surgery With PRF or Collagen Sponge
This study aims to compare platelet-rich fibrin (PRF) and an absorbable collagen sponge in extraction sockets following impacted mandibular third molar removal in terms of postoperative clinical healing and periodontal and…
- Conditions
- Impacted Mandibular Third Molar, Wound Healing, Postoperative Pain
- Trial name
- PRFvsCOLL-3M (NCT07530068)
- Testing
- Platelet-rich fibrin (PRF), Absorbable Collagen Sponge
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Gazi University
Tooth, Impacted, Dental Anxiety
Evaluation of the Effectiveness of Aromatherapy on Anxiety, Vital Signs, and Postoperative Complications in Lower Impacted Wisdom Tooth Surgery
Dental anxiety is considered to be one of the fears and concerns associated with dental treatment. Lavender has a relaxing and anxiolytic aroma.
- Trial name
- NCT06101446
- Testing
- Lavander Aromatherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Tooth Decay, Hydroxyapatite
Hydroxyapatite-toothpaste and Enamel Caries in the Primary Dentition
This multicenter, non-inferiority trial randomized, double-blind, active controlled parallel group study evaluates the hypothesis that the home regular use of a toothpaste containing microcrystalline hydroxylapatite (HAP) (test…
- Conditions
- Tooth Decay, Hydroxyapatite, Tooth Demineralization, Tooth Diseases
- Trial name
- ECIPDEN17 (NCT03553966)
- Testing
- Prophylactic, Cleaning teeth, Restorative dentistry
- Where
- Poland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Dr. Kurt Wolff GmbH & Co. KG
Sports Concussion
Use of Resveratrol to Decrease Acute Secondary Brain Injury Following Sports-Related Concussions in Boxers
Sports-related concussions are a serious problem in football, boxing, and other full contact sports. After experiencing consecutive concussions, there is an increase in neurological deficits that can lead to long-term cognitive…
- Trial name
- REPAIR (NCT01321151)
- Testing
- Resveratrol
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Tooth, Impacted
Dental Stem Cells and Bone Tissue Engineering (CELSORDINO)
The main limitation in bone regeneration is the lack of vascularization of the newly shaped tissue. The main objective of this project is to check if the simultaneous differentiation of dental mesenchymal stem cells toward…
- Trial name
- CELSORDINO (NCT03194451)
- Testing
- non-interventional study
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Traumatic Brain Injury
The Impact of Traumatic Brain Injury in the Elderly
A better understanding of the impact of Traumatic Brain Injury (TBI) in the elderly, in terms of brain damage, cognitive and motor functions, sleep quality and quality of life is necessary due to the increasing incidence and…
- Trial name
- NCT04070092
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Irriversible Pulpitis
Analyzing the Impact of Occlusal Reduction on the Pain Following Root Canal Therapy in Molar Teeth With and Without Pain in Turkish Patients.
Introduction: This study aimed to compare the intensity of postoperative pain after single-visit root canal treatment of symptomatic or asymptomatic teeth following occlusal reduction.
- Trial name
- NCT06953856
- Testing
- occlusal reduction
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Trismus, Edema
Low Laser Light Therapy After Impacted Third Molar Removal
Third molars extraction is a surgery frequently performed in dentistry. It is generally associated to a great postoperative distress rendered by pain, swelling and trismus, caused by surgical trauma inflammation.
- Conditions
- Trismus, Edema, Pain
- Trial name
- NCT02602431
- Testing
- Extra-oral laser irradiation, Intra-oral laser irradiation
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Mindfulness, Woman, Stress, Disaster
A Randomized Controlled Trial of Mindfulness-Based Stress Reduction for Reducing Perceived Stress in Women Impacted by Large-Scale Disasters
Hypothesis: Women affected by large-scale disasters who participate in an eight-week Mindfulness-Based Stress Reduction (MBSR) program will experience significantly lower perceived stress levels compared to those in the control…
- Trial name
- RCT (NCT07283601)
- Testing
- MBSRP
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Smile Esthetics, Interdental Spacing
Effect of Interdental Spacing and Crown Width Discrepancy on Smile Esthetics in Primary Dentition
This cross-sectional study aims to evaluate how interdental spacing and crown width discrepancies in primary dentition influence the perception of smile esthetics.
- Conditions
- Smile Esthetics, Interdental Spacing, Esthetic Perception
- Trial name
- NCT07480239
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Marmara University
Impacted Third Molar Tooth
Chlorhexidine Gel Versus Alvogyl Following Surgical Extraction of Impacted Mandibular Third Molar
Background: One of the most frequent surgical operations in dentistry is the surgical extraction of the impacted mandibular third molar, which is accompanied by a sequelae of swelling, trismus, and pain.
- Trial name
- NCT06144983
- Testing
- Alvogyl, Chlorhexidine Gluconate
- Where
- Iraq
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Fibrin/Therapeutic Use, Blood Platelets
Effects of the Use of Platelet-rich Fibrin on Bone Regeneration After Impacted Third Molar Surgery
The purpose of this study is to evaluate the bone regeneration after impacted third molar surgery on split mouth design using platelet-rich fibrin.
- Conditions
- Fibrin/Therapeutic Use, Blood Platelets, Molar, Third, Bone Regeneration
- Trial name
- NCT02890680
- Testing
- Platelet-rich fibrin, Control group
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Malaria, Malaria, Asymptomatic Parasitaemia
Impact of Scaling up Mass Testing, Treatment and Tracking on Malaria Prevalence Among Children
Malaria poses a serious burden in sub-Sahara Africa. Efforts are ongoing to scale up interventions that work. These include the use of Long Lasting Insecticidal Nets (LLIN), Intermittent Preventive Treatment in children (IPTc)…
- Trial name
- NCT04167566
- Testing
- Artemisinin Combination Therapy ACTs
- Where
- Ghana
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Noguchi Memorial Institute for Medical Research
Lingual Nerve Injuries
Removal of Impacted Molars With Lingual Split Technique
This research assesses removal of mandibular third molars by the lingual split technique with using Walter's lingual retractor for retracting lingual flap, and evaluates the lingual nerve injury that may result after applying…
- Trial name
- NCT05946317
- Testing
- Lingual nerve function assessed after removal of mandibular third molar with lingual split technique
- Where
- Syria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Latakia University
Wound Heal, Quality of Life
Clinical Wound Healing After Lower 3rd Molar Fully-impacted Surgery With 2 Types of Flap
The dehiscence distal to the second molar after lower third molar extraction is very common because the access flap for surgical extraction cannot be repositioned on a portion of healthy bone to guarantee suture support.
- Conditions
- Wound Heal, Quality of Life, Dehiscence
- Trial name
- NCT04314765
- Testing
- lower third molar extraction
- Where
- Italy
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Healthy Adult Participants
Psychological Impact of an 80-km Ultra-Endurance Race
Ultra-endurance races (ultra-marathons) take place under extreme environmental conditions, over long distances, involving prolonged physical activity and multiple psychological and physiological challenges.
- Trial name
- PSYTRAIL-80 (NCT07522307)
- Testing
- Completion on a tablet of self-administered questionnaires about their emotions/feelings before, during (kilometers 25, 38, 48, and 56), and at the finish line (80th kilometer)
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans