Clinical trials: Tooth Caries
Teeth; Lesion, Dental Root Caries
5-year Clinical Evaluation of Cavity Lining on the Restoration
The purpose of this double-blind, randomized trial is to compare the clinical performance of a composite restorations in root surface carious lesions with or without resin modified glass ionomer lining.
- Trial name
- NCT03802539
- Testing
- Glass Liner
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Caries in Children
Assessment of Dental Caries Among a Group of Institutionalized Orphan Children Compared to Parented School Children
Children from two orphanages will be examined for dental caries experience, in comparison to parented school children.
- Trial name
- NCT05652231
- Testing
- caries assessment
- Where
- Egypt
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Ahram Canadian University
pH, Microbiome
Oral Changes With Caloric and no Caloric Sweeteners
The objective of this clinical trial is to compare the effect that the intake of beverages without sweeteners, added with non-caloric sweeteners (stevioside) and caloric sweeteners (sucrose) on oral pH and dental biofilm…
- Conditions
- pH, Microbiome, Dental Plaque
- Trial name
- NCT05852145
- Testing
- Stevioside, Sucrose, Natural water
- Where
- Mexico
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Dental Caries
the Antibacterial Effect of Zinc ,Silver and Fluoride
natural teeth will be filled with the 3 different material then the dentin sample will be collected ,bacterial culture and elementary analysis will be done
- Trial name
- NCT04329858
- Testing
- silver modified glass ionomer, zinc modified, conventional glass ionomer
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Hygiene, Probiotics, Periodontitis
Probiotic Nanofiber Floss and Subgingival Pathogen Suppression
This randomized, double-blind, crossover clinical trial evaluated the effect of a probiotic-containing nanofiber dental floss on subgingival red complex periopathogens and gingival health in periodontally healthy individuals.
- Conditions
- Dental Hygiene, Probiotics, Periodontitis, Prevention of Dental Caries, Gingivitis and Periodontal Diseases
- Trial name
- NCT07149493
- Testing
- Probiotic nanofiber floss
- Where
- Czechia
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Dental Caries in Children, Wound Heal
Biostimulation After Tooth Extraction
This study evaluated the effect of low-level laser therapy on postoperative pain and wound healing in children undergoing primary molar extractions 40children, 6-10 years of age, systemically healthy, and had atraumatic…
- Trial name
- NCT06018584
- Testing
- Tooth extraction
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hazal Özer
Dental Caries in Children
Supportive Caries Preventive Programme in Children Undergoing Dental General Anaesthesia
Early childhood caries is a persistent problem often leading to dental treatment under general anaesthesia (GA). Thus, this study was to investigate the preventive effect of two additional intensive oral hygiene appointments…
- Trial name
- NCT05110534
- Testing
- additional oral hygiene appointments
- Where
- Germany
- Volunteers
- 406 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Primary Dental Caries, Multisurface Origin (Diagnosis)
Clinical Trial NuSmile Crowns
A clinical trial comparing two types of NuSmile anterior crowns to composite strip crowns on anterior dental restorations.
- Trial name
- NCT04975321
- Testing
- Nu Smile Zirconia crown, Nu Smile Pre Veneered crown, Composite strip crown
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University of Washington
White Spot Lesion of Tooth
Remineralizing Effect of Different Silver-containing Agents on Initial Caries Lesions in Primary Teeth in Children
The aim of the present work is to study the effect of the application of Silver diamine fluoride (SDF) and a novel green synthesized Nano-silver fluoride (NSF) on early enamel lesions in primary teeth.
- Trial name
- NCT06489093
- Testing
- NSF, SDF+KI, Control group
- Where
- Bulgaria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Plovdiv Medical University
Dental Caries
Evaluation of Oral Hygiene Products in an In Situ Caries Model
The study will evaluate and compare the potential anti-caries efficacy of a test regimen: placebo (fluoride free) toothpaste (twice daily use) plus fluoride mouthwash (once daily use), in comparison with brushing with a placebo…
- Trial name
- NCT02399163
- Testing
- Fluoride free toothpaste, Fluoride toothpaste, Fluoride mouthwash
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dental Caries, Early Childhood Caries
Oral Health and Dental Caries Prevention Intervention for Children in Romania
During 2019-2020, the National Oral Health Survey evaluated a significant sample of children aged 5, 6 and 12 years, gathering baseline data on oral health.
- Conditions
- Dental Caries, Early Childhood Caries, Quality of Life
- Trial name
- Smilebright (NCT06441500)
- Testing
- Daily tooth brushing programme
- Where
- 5 sites in Romania
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy "Victor Babes" Timisoara
White Spot Lesions, Caries
Randomized Trial on Resin Infiltration in Deciduous Teeth
It was hypothesized that resin infiltration in conjunction with fluoride varnish treatment of smooth-surface caries lesions in deciduous teeth reduce considerably the progression of treated caries lesions, compared to fluoride…
- Trial name
- infiltration (NCT01881100)
- Testing
- resin infiltration, fluoride varnish
- Where
- Poland
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Dental Caries
Evaluation of Implants Placed Immediately or Delayed Into Extraction Sites
The purpose of this study is to determine the difference in success when placing implants immediately into an extraction site compared to delaying the implant placement until the extraction site has healed.
- Trial name
- NCT00067392
- Testing
- Dental Implant
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Early Childhood Caries
Effect of Application Time of 38% Silver Diamine Fluoride Solution on Arresting Dental Caries in Preschool Childre
To determine the optimal application time of silver diamine fluoride (38% SDF) in arresting dental caries in the primary teeth of preschool children.
- Trial name
- NCT04655430
- Testing
- 3-second SDF application, 5-second SDF application, 10-second SDF application
- Where
- Hong Kong
- Volunteers
- 665 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Dental Caries, Gingivitis
Anticaries Effect of Probiotic Lactobacillus Brevis CD2 (Lb CD2).
In a previous study the efficacy of Lb CD2 on interim covariates related to caries development was tested. So, it was decided to plan a new study on schoolchildren from the same area.
- Trial name
- NCT01778699
- Testing
- lozenges
- Where
- Italy
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Dental Caries
Effect of Water Rinsing After Topical Fluoride Application on Dental Plaque pH
The aim of this study was to determine whether rinsing with water or cleansing teeth after topical fluoride therapy affect the dental plaque pH.
- Trial name
- NCT01569165
- Testing
- cleansing teeth after topical fluoride therapy
- Where
- Iran
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Allergic Rhinitis, Asthma in Children
Oral Findings in Pediatric Patients With Allergic Rhinitis and/or Asthma
The aim of the study was to evaluate if there were differences in oral findings between patients diagnosed with allergic rhinitis and/or asthma and a control group of health people.
- Conditions
- Allergic Rhinitis, Asthma in Children, Dental Caries, Periodontal Diseases
- Trial name
- NCT05576142
- Testing
- Oral examination
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Deep Caries
Silver Diamine Fluoride After Minimal Caries Removal Technique in Asymptomatic Young Permanent Teeth With Deep Caries
This study is comparing between the Silver Diamine Fluoride after minimal caries removal versus glass ionomer in permanent teeth with open apex
- Trial name
- NCT03568474
- Testing
- Silver Diamine Fluoride, Glass Ionomer
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Pulp Protection in Selective Carious Tissue Removal
Although selective removal of carious tissue to soft dentin (SRCT-S) has been proposed as the standard of care for the management of deep dentin caries, it is unclear whether a cavity liner is necessary.
- Trial name
- PULPROTECT (NCT04250142)
- Testing
- Self-etching Adhesive, Glass Ionomer
- Where
- Chile
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Talca
Caries,Dental
Caries-associated Saliva Biomarkers Among Different Races
discover possible differences and develop effective preventative interventions by examining the relationship between salivary biomarkers and caries prevalence across different racial groups and Detect risk factors involved in…
- Trial name
- NCT06838182
- Testing
- Salivary biomarkers tests
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University