Clinical trials: Tooth Movement
Malocclusion, Corticotomy
Evaluation of Corticotomy-Assisted Canine Retraction Rate
The goal of this split-mouth randomized clinical trial is to evaluate the effectiveness of corticotomy on maxillary canine retraction rate compared to conventional orthodontic techniques.
- Conditions
- Malocclusion, Corticotomy, Canine Retraction, Orthodontic Tooth Movement
- Trial name
- BMU/2026/8506 (NCT07879066)
- Testing
- Experimental: Corticotomy¬-Assisted Canine Retraction, Active Comparator / Control: Conventional Canine Retraction
- Where
- Bangladesh
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tanzila Rafique
Accelerate Tooth Movement
Impact of Various Acceleration Techniques on En-masse Retraction of Maxillary Anterior Teeth
Impact of Various Acceleration Techniques on En-masse Retraction of Maxillary Anterior Teeth: A Digital Software Evaluation (Comparative Clinical Study)
- Trial name
- LLLT- piezo (NCT07873853)
- Testing
- low level LAZER therapy., Retraction of Maxillary Anterior Teeth (en-mass) with conventional methods., Piezocision-assisted orthodontic retraction
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Malocclusion, Canine Retraction
Maxillary Canine Retraction Using Stainless Steel and Titanium-molybdenum Alloy Wires in TAD-supported Segmental Mechanics
The goal of this randomized clinical study is to compare the effectiveness of stainless steel (SS) and titanium-molybdenum alloy (TMA) wires for maxillary canine retraction using TAD-supported segmental mechanics.
- Conditions
- Malocclusion, Canine Retraction, Orthodontics, Tooth Movement Techniques
- Trial name
- NCT07645417
- Testing
- A titanium-molybdenum alloy reverse-closing loop, A stainless steel reverse closing loop
- Where
- Bangladesh
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Tanzila Rafique
Pain Perception, Root Resorption
The Potential Effect of the Local Administration of Vitamins C and E on Orthodontic Treatment: A Randomized Clinical Trial
Brief Summary of the Study This study investigates the effects of locally administered vitamins C and E on orthodontic tooth movement during the initial stage of treatment.
- Conditions
- Pain Perception, Root Resorption, Rate of Orthodontic Tooth Movement, Biomarkers
- Trial name
- NCT06847880
- Testing
- 1: Vitamin C Supplementation, Vitamin E Supplementation, Saline Solution (Control)
- Where
- 3 sites in Iraq
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Orthodontic Tooth Movement
Acceleration of Tooth Movement Using PRP and Photobiomodulation With Clear Aligners
This study compares the effectiveness of two adjunct therapies- photobiomodulation (low-level laser therapy) (PBM) and localized platelet-rich plasma (PRP) injections in accelerating orthodontic tooth movement.
- Trial name
- NCT07795073
- Testing
- Platelet Rich Plasma (PRP) injection, photobiomodulation (PBM) Therapy, clear aligner(12-hour wear protocol)
- Where
- Yemen
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sana'a University
Malocclusion, Orthodontic Tooth Movement
Micro-osteoperforation Versus Photobiomodulation Therapy for Accelerating Maxillary Canine Retraction
Orthodontic treatment often requires moving the upper canine teeth (the pointed teeth) into the spaces left after removing premolar teeth.
- Conditions
- Malocclusion, Orthodontic Tooth Movement, Maxillary Canine Retraction
- Trial name
- MOP-PBMT (NCT07658235)
- Testing
- Micro-osteoperforation (MOP), Photobiomodulation Therapy using 976 nm Diode Laser, Conventional orthodontic canine retraction
- Where
- Iraq
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kufa University
Orthodontic Tooth Movement, Low Level Laser Therapy
Comparison of Rate of Tooth Movement Between MOPs vs MOPs & LLLT Combined
Orthodontic treatment is often prolonged, requiring years to achieve desirable outcomes. The prolonged duration of treatment increases the risk of complications such as root resorption, periodontal damage, and patient…
- Conditions
- Orthodontic Tooth Movement, Low Level Laser Therapy, Canine Retraction
- Trial name
- NCT07626580
- Testing
- Micro-osteoperforation, Low Level Laser Therapy and Micro-osteoperforations Combined
- Where
- Pakistan
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Acceleration of Tooth Movement
The Effect of Low-Level Laser Therapy on Accelerating Tooth Movement and Reducing Pain During Orthodontic Treatment
Orthodontic treatment is a common and effective approach to correcting dental malocclusions and improving oral function and aesthetics.
- Trial name
- LLLT (NCT07591948)
- Testing
- Low level laser therapy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sana'a University
Orthodontic Tooth Movement
Clinical Trial to Assess the Efficacy of Reducing the Aligners' Wear Protocol
The hypothesis of this project is that replacing the current 7-day wear protocol with a 3-day wear protocol, while integrating less tooth movement per aligner (reduce the amount of activation per aligner) may produce more…
- Trial name
- NCT05905224
- Testing
- Invisalign 7-day wear protocol, Invisalign 3-day wear protocol
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Florida
Bone Loss, Tooth Movement
The Introduction of a Novel PAOO Technique
The aim of this study is to evaluate in a prospective, randomized, controlled clinical trail the effectiveness of preorthodontic piezotomy combined with a buccal bone augmentation (in other name periodontlly accelerated…
- Trial name
- NCT05264480
- Testing
- Bone augmentation with minimally invasive corticotomy (piezotomy), Bone augmentation without corticotomy
- Where
- Hungary
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Orthodontic Tooth Movement
GCF Volume Changes in Aligners and Fixed Appliances
Orthodontic tooth movement induces biological responses in periodontal tissues that can be reflected by changes in gingival crevicular fluid (GCF).
- Trial name
- GCF-OTM (NCT07480538)
- Testing
- Clear Aligner Therapy, Fixed Appliance
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Class II Malocclusion, Orthodontic Tooth Movement
Effect of Photobiomodulation on Orthodontic Tooth Movement
This study evaluated whether photobiomodulation (PBM), a form of low-level light therapy, can accelerate orthodontic tooth movement during canine distalization in adult patients undergoing fixed orthodontic treatment.
- Trial name
- NCT07390357
- Testing
- 635-nm photobiomodulation
- Where
- Poland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Effect of Piezocision and Injectable Platelets Rich Fibrin on Tooth Movement
Evaluation of Piezocision Versus Injectable Platelet-rich Fibrin During Orthodontic Canine Retraction Orthodontic Canine Retraction: A Comparative Clinical Study
Comparison of piezocisin and injectable platelets rich fibrin during canine retraction
- Trial name
- NCT07239024
- Testing
- Iprf and piezocision
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Maxillary Canine Retraction, Local Calcitriol Delivery
Clinical Evaluation of Local Calcitriol Delivery on Maxillary Canine Retraction
This study will evaluate the effect of locally applied Calcitriol on dental and skeletal changes during upper canine retraction.
- Conditions
- Maxillary Canine Retraction, Local Calcitriol Delivery, Orthodontic Tooth Movement
- Trial name
- CALCR25 (NCT07200349)
- Testing
- Calcitriol Delivery
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Tooth Movement Techniques, Distalization by Miniscrews
Evaluation of Three-Dimensional Printed Orthodontic Molar Distalizer
A randomized clinical trial to evaluate a newly designed 3D printed miniscrew-supported molar distalization device in comparison to the conventional miniscrew-supported distal jet appliance in correction of Class II malocclusion…
- Trial name
- RCT (NCT07191158)
- Testing
- Group 1 conventional, Group 2 3D printed
- Where
- Iraq
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Maxillary Transverse Deficiency Class I Malocclusion Vitamin D Deficiency Orthodontic Tooth Movement Adolescent Health
Effect of Serum Vitamin D on MARPE Treatment Response
A total of 30 patients are planned to be included in the study during the first half of 2025, who will apply to the clinic. In our clinical routine, approximately 30% of RME patients are treated using the MARPE method.
- Trial name
- NCT06943443
- Testing
- Miniscrew-Assisted Rapid Palatal Expansion (MARPE) Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Orthodontic Tooth Movement, Intrusion of Tooth
Evaluation of Root Resorption Following Different Mandibular Incisors Intrusive Mechanics
Evaluation of root resorption following different mandibular incisors intrusive mechanics : A randomized clinical trial
- Conditions
- Orthodontic Tooth Movement, Intrusion of Tooth, Resorption, Root
- Trial name
- NCT05414019
- Testing
- Mini-screw, Utility arch, Nitinol reverse curve wire
- Where
- Egypt
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Malocclusion, Clear Aligner Appliance
Impact of Aligner Replacement Protocols on Predictability of Planned Dental Movements: Evaluation of Double Aligner
The study will evaluate the impact of replacing aligners after 7 days with new aligners made of different materials on the predictability of planned dental movements.
- Conditions
- Malocclusion, Clear Aligner Appliance, Orthodontics, Tooth Movement
- Trial name
- NCT06882395
- Testing
- Group 1: FLX aligners for 10 days, Group 3: FLX aligners for 7 days, followed by new FLX aligners for 3 days., Group 2: FLX aligners worn for 7 days, followed by FLX35 aligners for 3 days.
- Where
- Brazil
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Neodent
Malocclusion, Tooth Movement Techniques
Efficacy of Orthodontic Tooth Movement Using Beveled and Conventional Attachments in Aligners
The objective of this study is to evaluate the efficacy of tooth movement using beveled attachments and conventional attachments.
- Trial name
- NCT06873932
- Testing
- Arm 1: Beveled Attachments, Conventional Rectangular Attachments
- Where
- Brazil
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Neodent
Rate of Tooth Movement in Orthodontic Patients
Evaluation of Effect of Platelet-Rich Fibrin on Orthodontic Tooth Movement: a Split Mouth Randomised Controlled Trial
it is a randomized control trial and aims at investigating the effects of PRF on rate of tooth movement and root length to be tested on larger sample size of pakistani population
- Trial name
- NCT06634017
- Testing
- Platelet rich fibrin
- Where
- Pakistan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences