Clinical trials: Tooth Movement, active
Angle Class I Malocclusion, Dental Crowding
Clinical Performance of Direct-Printed Versus Thermoformed Aligners
The goal of this study is to evaluate and compare the clinical effectiveness of in-office directly 3D-printed clear aligners versus conventional multilayered thermoformed aligners.
- Conditions
- Angle Class I Malocclusion, Dental Crowding, Tooth Spacing
- Trial name
- NCT07637227
- Testing
- Direct-Printed Aligner, Thermoformed aligner
- Where
- 3 sites in Iraq
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Stage IV Periodontitis, Orthodontic Tooth Movement
Effect of MOPs During Orthodontic Movement in Periodontitis Patients
Micro-osteoperforations (MOPs) cause cortical bone injuries and consequently increase the expression of inflammatory mediators, allowing for increased bone and periodontal ligament remodeling associated with orthodontic movement.
- Trial name
- MOPorthoperi (NCT06068270)
- Testing
- Micro-ostoperforations (MOPs)
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- Universidad Complutense de Madrid
Orthodontics
Study of the Use of Orthopulse Photobiomodulation
This PMCF study evaluates the safety and performance of OrthoPulse photobiomodulation to accelerate tooth movement during alignment with fixed appliances.
- Trial name
- NCT05650359
- Testing
- OrthoPulse, No intervention
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Biolux Technology GmbH
Tooth Mobility, Injectable Platelet-rich Fibrin
Evaluating the Effect of Injectable Platelet-rich Fibrin on Accelerating Orthodontic Tooth Movement
One of the main goals of orthodontic treatment is the reduction of treatment time through faster tooth movement. The previous studies evaluating platelet-rich fibrin (PRF) and orthodontic tooth movement (OTM) are limited, which…
- Trial name
- NCT06302296
- Testing
- injectable form of PRF
- Where
- Syria
- Volunteers
- 14 people
- Sponsor
- Hama University
Dental Malocclusion, Maxillary Deficiency
Effect on Periodontal Phenotype of Flapless Piezoincission During Orthodontic Treatment
Research Question While the reduction in treatment times and the patient satisfaction after periodontally accelerated osteogenic orthodontics (PAOO) are well sustained in the scientific literature, there is still controversy…
- Trial name
- Piezo_Ortho (NCT06315348)
- Testing
- flapless alveolar decortication with augmentation
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Complutense de Madrid
Orthodontic Tooth Movement, Intrusion of Tooth
Evaluation of Root Resorption Following Different Mandibular Incisors Intrusive Mechanics
Evaluation of root resorption following different mandibular incisors intrusive mechanics : A randomized clinical trial
- Conditions
- Orthodontic Tooth Movement, Intrusion of Tooth, Resorption, Root
- Trial name
- NCT05414019
- Testing
- Mini-screw, Utility arch, Nitinol reverse curve wire
- Where
- Egypt
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Rate of Tooth Movement in Orthodontic Patients
Evaluation of Effect of Platelet-Rich Fibrin on Orthodontic Tooth Movement: a Split Mouth Randomised Controlled Trial
it is a randomized control trial and aims at investigating the effects of PRF on rate of tooth movement and root length to be tested on larger sample size of pakistani population
- Trial name
- NCT06634017
- Testing
- Platelet rich fibrin
- Where
- Pakistan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Crowding of Anterior Mandibular Teeth
Evaluating the Efficacy of Micro-Osteoperforations Technique on the Orthodontic Tooth Movement Acceleration in Moderate Mandibular Anterior Crowding Cases Treated With Clear Aligners
Patients with moderate mandibular anterior crowding will be treated in this study. The efficacy of micro-osteoperforations technique by special drill in accelerating orthodontic tooth movement during clear aligners therapy will…
- Trial name
- NCT05492773
- Testing
- Micro-osteoperforations Technique, Active comparater
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hama University
Clear Aligner Appliance
Evaluation of the Efficacy of Injectable Platelet-rich Plasma in Tooth Movement Acceleration With Clear Aligner
Aim of the study is evaluation of the efficacy of injectable platelet-rich plasma in orthodontic tooth movement acceleration with clear aligner
- Trial name
- NCT07103551
- Testing
- Platelet-rich plasma
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Accelerate Tooth Movement
Accelerated Orthodontics With Alveolar Decortication Plus CGF Injection
The aim of the present study is to evaluate alveolar bone decortication combined with CGF Injection on tooth movement acceleration
- Trial name
- NCT06975358
- Testing
- Alveolar decortication plus CGF injection, canine retraction without acceleration
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Safa Basiouny Alawy
Malocclusions
Effects of Vitamin D in Patients Undergoing Fixed Orthodontic Mechanotherapy
The goal of this interventional research is to determine the impact of vitamin D intake on substances in saliva, pain, tooth movement, and the density of the bone around teeth in patients during orthodontic treatment.
- Trial name
- NCT07299552
- Testing
- Vitamin D (Calcitriol)
- Where
- Malaysia
- Volunteers
- 48 people
- Sponsor
- Hospital Universiti Sains Malaysia
Malocclusion, Corticotomy
Evaluation of Corticotomy-Assisted Canine Retraction Rate
The goal of this split-mouth randomized clinical trial is to evaluate the effectiveness of corticotomy on maxillary canine retraction rate compared to conventional orthodontic techniques.
- Conditions
- Malocclusion, Corticotomy, Canine Retraction, Orthodontic Tooth Movement
- Trial name
- BMU/2026/8506 (NCT07879066)
- Testing
- Experimental: Corticotomy¬-Assisted Canine Retraction, Active Comparator / Control: Conventional Canine Retraction
- Where
- Bangladesh
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tanzila Rafique
Accelerated Orthodontic Tooth Movement
Comparing MOP, Prostaglandin E1, and Calcitriol to Accelerate Orthodontic Tooth Movement
This study will compare the effects of MOP (micro-osteoperforation), prostaglandin E1, and calcitriol on the rate of orthodontic tooth movement.
- Trial name
- acceleration (NCT07842120)
- Testing
- PGE₁ (pharmacological) • Agent: Prostaglandin E1, Calcitriol (1,25-(OH)₂D₃) local injection • Agent: Calcitriol (1,25-(OH)₂D₃) Vitamin D3, microosteoperforation MOP (surgical)
- Where
- 2 sites in Iraq
- Volunteers
- 60 people
- Sponsor
- Ghufran Dhari Awad
Malocclusion of Anterior Teeth
Effects of Laser Therapy and Vitamin D Pills on Braces Tooth Movement: A Random Controlled Study
This clinical trial aims to evaluate the efficacy of low-level laser therapy (LLLT) in conjunction with oral vitamin D3 supplementation in accelerating orthodontic tooth movement in adults with crowded mandibular anterior teeth…
- Trial name
- LLLT (NCT07286474)
- Testing
- Cholecalciferol (Vit D3), Low-Level Laser Therapy, Fixed Orthodontic Appliance
- Where
- Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Mixed Dentition Using Sequential Dental Aligners
This Study Will Examine Shortened Treatment Wear Time for Patients With Mixed Dentition Using AirFlex Aligner, Sequential Dental Aligners.
This study will examine shortened treatment wear time for patients with mixed dentition using sequential dental aligners. Using the existing AirFlex aligner design that patients with permanent dentition use, it may be possible to…
- Trial name
- NCT07220317
- Testing
- Sequential Aligners
- Volunteers
- 45 people
- Sponsor
- OrthoFX
TMD/Orofacial Pain, Malocclusions
Evaluation of the Effects of Orthognathic Surgeries on the Temporomandibular Joint Using a Mandibular Movement Analyzer Device
Condylar position and mandibular motion assessment with digital facebows Arcus Digma III before and after orthognathic surgery.
- Trial name
- NCT07828041
- Where
- Hungary
- Volunteers
- 50 people
- Sponsor
- Semmelweis University
Neuromuscular Diseases, Obesity (Disorder)
Gait Analysis Parameter and Upper Limb Evaluation in Adult Patients With Neurological or Metabolic Pathology
The ActiLiège-Adult study is a prospective, longitudinal, observational study designed to collect natural history data on adult patients with neurological or metabolic diseases affecting movement.
- Conditions
- Neuromuscular Diseases, Obesity (Disorder), Myotonic Dystrophy 1, Myasthenic Syndrome
- Trial name
- Acti-Adult (NCT07136844)
- Testing
- Syde, Dynamometric measurements of muscle strength, The 6-minute walk test (6MWT)
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Liege
Dental Implants, Osseointegration
Movement of Dental Implants During Osseointegration
Prospective multicenter observational study assessing whether dental implants undergo three-dimensional positional change between placement (T0) and pre-loading after osseointegration (T1).
- Trial name
- MOVs-OI (NCT07297147)
- Where
- 3 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Aula Dental Avanzada
Lower Anterior Crowding
Evaluation of Accuracy of 3D Printed Aligners in Comparison to Thermoformed Aligners in Orthodontic Patients
The goal of this randomized clinical trial is to compare the accuracy of tooth movement achieved by 3D printed aligners versus thermoformed aligners in patients with lower anterior crowding.
- Trial name
- Aligner (NCT07496892)
- Testing
- 3d printed aligner, thermoformed aligner
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Cairo University
Malocclusion
Comparison of Orthodontic Molar Protraction With and Without Adjunctive Surgery
This study will compare orthodontic molar protraction with and without adjunctive periodontally accelerated osteogenic orthodontic (PAOO) surgery prior to orthodontic tooth movement.
- Trial name
- PAOO (NCT03794726)
- Testing
- Orthodontic Molar Protraction and PAOO, Orthodontic Molar Protraction
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham