Clinical trials: Tooth Plaque
Chronic Gingivitis, Plaque Induced
Efficacy of a Plaque Disclosing Toothpaste on Home Oral Hygiene Procedures
Plaque accumulation on tooth and gingival surfaces is a causative factor for oral diseases such as demineralization, dental caries, gingivitis, and periodontitis.
- Trial name
- NCT03287011
- Testing
- Shoplaq toothpaste, Colgate toothpaste
- Where
- Malaysia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Segi University
Dental Plaque
Effect of Different Mouthrinses in Plaque Formation
Although several studies have assessed the efficacy of chlorhexidine in treating gingivitis and reducing biofilm formation, the side effects of a long-term use are unpleasant for patients.
- Trial name
- NCT02695901
- Testing
- Chlorhexidine gluconate 0.12% (PerioGard®), Nanoparticle solution of M. alternifolia oil (0.3%).
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Maria
the Optimum Brushing Force for Dental Plaque Removal and the Effect of Brushing Force on Enamel Characteristic
Evaluation of the Optimum Brushing Force on Dental Plaque Removal and the Abrasive Effect of Brushing Force on Enamel Surface.
Objective 1. To determine the optimum brushing force for dental plaque removal. 2. To investigate the effect of brushing force on enamel characteristic.
- Trial name
- NCT04675736
- Testing
- brushing force
- Where
- Thailand
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Plaque, Dental, Dental Plaque Induced Gingivitis
The Effect of Photodynamic Therapy on Plaque in Orthodontic Patients
This randomized controlled trial will be conducted on 40 orthodontic patients at the Department of Orthodontics, University Hospital Centre Zagreb, Croatia. Respondents will be randomly allocated into 4 groups (n=10).
- Conditions
- Plaque, Dental, Dental Plaque Induced Gingivitis, White Spot Lesion
- Trial name
- NCT06331442
- Testing
- Photodynamic therapy, Tricalcium phosphate (TCP) varnish with 5% NaF, Chlorhexidine varnish
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Dental Plaque
Antibacterial Effect of the Infusion of Green Tea Used as a Mouthwash on Saliva and Bacterial Plaque
Given that the participation of oral microorganisms in the development of the most prevalent pathologies of the oral cavity is unquestionable, efforts have been made to create agents that allow controlling these bacteria.
- Trial name
- NCT04410666
- Testing
- Green Tea mouthwash
- Where
- Paraguay
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Julieta María Méndez Romero
Child, Saliva
Effect of 5% Aqueous Propolis in Salivary and Dental Plaque pH in Children
This study aims to investigate the changes in saliva and dental plaque pH after consuming sugar-free chewing gum containing 5% of aqueous propolis in children aged between 8-11 years.
- Conditions
- Child, Saliva, Dental Plaque
- Trial name
- NCT05793099
- Testing
- Effect of aqueous propolis gums in salivary and dental plaque pH in children
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Damascus University
Plaque Induced Gingivitis, Plaque, Dental
Antibacterial Effect of Paradontax Toothpaste
The purpose of the study is to test the antibacterial effect of Parodontax toothpaste on plaque formation, and thus gingivitis compared to placebo toothpaste.
- Trial name
- NCT05441371
- Testing
- Toothpaste; Paradontax
- Where
- Norway
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Oral Hygiene, Dental Plaque
Evaluation of the Effect of Oil Pulling
The objectives of this study were to evaluate the inhibitory effect on plaque and the tooth discoloration associated with agents used in the chemical plaque control of oil pulling in comparison with chlorhexidine-containing…
- Trial name
- NCT05304338
- Testing
- Chlorhexidine, Oil Pulling, Distilled Water
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Plaque, Dental
Clinical Evaluation of an Electric and a Manual Toothbrush in Removal of Dental Plaque
The study aimed to evaluate the efficacy of manual and electric toothbrush on dental plaque removal by using various intraoral imaging systems.
- Trial name
- NCT05372848
- Testing
- Manual toothbrush, Electric toothbrush
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marmara University
Healthy
The Effect of Portable AR on Tooth Brushing Skill for Elementary School Students
The aim of this study An augmented reality (AR) simulation toothbrushing machine was developed to train proper brushing technique for children.
- Trial name
- NCT05956262
- Testing
- AR-toothbrush machine, Teach proper brushing skills
- Where
- Taiwan
- Volunteers
- 601 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Periodontal Diseases, Tooth Abrasion
The Effect of Bristle Brush, Rubber Cup, and Air Polishing on Tooth Surface Roughness of Scaled Teeth
This study investigates the effects of three polishing methods using a bristle brush, rubber cup, and air polishing on the surface roughness of scaled human teeth.
- Conditions
- Periodontal Diseases, Tooth Abrasion, Dental Plaque
- Trial name
- NCT06857474
- Testing
- Bristle Brush Polishing, Rubber Cup Polishing, Air Polishing
- Where
- Pakistan
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Dental Plaque
Oral Imaging for Porphyrin Biomarkers
The purpose of this study was to use the principle of fluorescence to identify oral diseases not readily visible to the naked eye.
- Trial name
- NCT03379337
- Testing
- Dental imaging
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Massachusetts Institute of Technology
Dental Plaque
Chlorhexidine Mouthrinses and Plaque Control
The aim of the present study was to compare antiplaque effectiveness of two commercial mouthrinses: 0.12 % Chlorhexidine alcohol base (CLX-A) versus a diluted 0.1% Chlorhexidine non-alcohol base with 0.1% of Formaldehyde (CLX-F).
- Trial name
- NCT01138943
- Testing
- Synthodont, Soludent
- Where
- Morocco
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hôpital Militaire De Rabat
Dental Plaque
Evaluating Commercial Anti-Plaque Products and Oral Rinse
Clinical research study to determine the anti-plaque efficacy of commerical dentifrices and an oral rinse.
- Trial name
- NCT01014143
- Testing
- Fluoride, Chlorhexidine digluconate, Fluoride, triclosan
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Oral Biofilm, Mouthwash
Antiplaque Effect of Essential Oils and 0.2% Chlorhexidine on an in Situ Model of Oral Biofilm Growth.
The accumulation and maturation of oral biofilm in the gingival margin is widely recognised to be the primary aetiological factor in the development of chronic gingivitis.
- Conditions
- Oral Biofilm, Mouthwash, Periodontitis
- Trial name
- NCT02124655
- Testing
- Essential oils, 0.2% chlorhexidine, Sterile water
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Root Resorption, Orthodontic Appliance Complication
Proteomics and Orthodontic Root Resorption
The majority of previous studies for early detection of Orthodontically Induced Inflammatory Root Resorption (OIIRR) were conducted to assess individual biomarkers which are representative of single biological pathway.
- Conditions
- Root Resorption, Orthodontic Appliance Complication, Orthodontic Pathological Resorption of External Root, Gingival Diseases
- Trial name
- NCT04291443
- Testing
- Heavy Force (225g), Light Force (25g)
- Where
- Iraq
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Oral Health, Oral Hygiene
Effectiveness of Personalized Oral Hygiene Education in Medical and Dental Students Over Two Years
This prospective cohort study is designed to evaluate the long-term effects of individualized oral hygiene education, known as Individually Trained Oral Prophylaxis (iTOP), on oral health outcomes in medical and dental students…
- Conditions
- Oral Health, Oral Hygiene, Periodontal Health, Dental Plaque
- Trial name
- iTOP (NCT07085013)
- Testing
- Individually Trained Oral Prophylaxis (iTOP)
- Where
- Bosnia and Herzegovina
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Mostar
Biofilms, Substantivity
Immediate Effect and Substantivity of the Essential Oils Without Alcohol on the Oral Biofilm in Situ
This study aims to evaluate the in situ antibacterial activity of a mouthwash containing essential oils with and without alcohol on undisturbed de novo plaque-like biofilm (PL-biofilm) up to 7 h after its application.
- Conditions
- Biofilms, Substantivity, Oils, Essential
- Trial name
- NCT02946814
- Testing
- essential oils, essential oils without mouthwash, sterile water
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Dental Plaque, Saliva Altered
Effects of Two Sugar Substituted Chewing Gums on Caries and Gingivitis Variables
The purpose of this study is to determine the effect of three times a day mastication, during a follow-up period of 4 weeks, of two sugar-substituted chewing gums on various factors associated with dental caries and gingivitis.
- Conditions
- Dental Plaque, Saliva Altered, Gingivitis
- Trial name
- NCT01578603
- Testing
- xylitol, casein phosphopeptide amorphous calcium phosphate complex
- Where
- Colombia
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Gingivitis, Plaque, Dental
Clinical Investigation Examining Plaque and Gingivitis Connected Toothbrush Compared to Non-Connected Toothbrush
The objective of this clinical research study is to assess plaque and gingivitis reductions of Connected Toothbrush compared to Non-Connected Toothbrush over a six-week clinical study.
- Trial name
- Connected (NCT04221334)
- Testing
- Electric Toothbrush, oral health care application
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive