Clinical trials: Tooth Socket
Tooth Extraction Site Healing, Alveolar Ridge Preservation
Assessment of the Impact of Neobone® (Biphasic Calcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction
The goal of this randomized clinical trial is to assess whether BCP (Biphasic Calcium Phosphate) improves alveolar ridge preservation (ARP) in patients who need tooth extraction.
- Trial name
- BCPARPBV (NCT07638358)
- Testing
- Neobone® (Biphasic Calcium Phosphate)
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Impacted Third Molar Tooth
Gum Health Gel in Post Extraction Sockets
This research studies the effectiveness of the Gum Health gel in minimizing post operative sequelae associated with the surgical removal of impacted mandibular third molars
- Trial name
- Gum Health gel (NCT06251141)
- Testing
- Gum Health gel, Gel foam
- Where
- Iraq
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Osteogenesis Imperfecta, Total Absence of Permanent Teeth
Site Preservation After Tooth Extraction
This study is mainly targeted affected teeth which could not be retained, and patients are willing to undergo implant repair at the later stage.
- Conditions
- Osteogenesis Imperfecta, Total Absence of Permanent Teeth, Tooth Socket
- Trial name
- NCT05258019
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Tooth Loss
Long- Term Follow-up of Extraction Socket Management
Twenty-nine patients needing single tooth replacement in aesthetic area were treated by extraction and socket preservation with saddle connective tissue graft between September 2009 and February 2012.
- Trial name
- NCT03410251
- Testing
- Socket preservation
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Liege
Dental Diseases
Investigation of Bacterial Adhesion and Bactericide Effect ex Vivo on Different Implant Restoration Materials
Investigation of bacterial adhesion and bactericide effect ex vivo on different implant restoration materials
- Trial name
- NCT04657757
- Testing
- Intraoral apparatus
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Tooth Extraction Status Nos
MicroRNA and MicroRNA Inhibitors Socket Study, Pilot Clinical Trial
To evaluate the efficacy of locally delivering plasmid DNAs encoding microRNAs, and/or microRNA inhibitors, in the promotion of osteogenesis and modulation of the inflammatory response on the basis of different clinical…
- Trial name
- NCT02579187
- Testing
- tooth extraction, CBCT scan, Anesthesia
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Gustavo Avila-Ortiz DDS, MS, PhD
Tooth Extraction Status Nos, Tooth Fracture
The Assessment of Curcuma Longa Potentials for Soft and Hard Tissue Healing in Fresh
The study will be conducted on 30 patients with split mouth design patients will be divided into curcumin and PRF groups patients will have bilateral tooth extraction one side will receive curcumin/PRF and the other side will be…
- Trial name
- NCT05816707
- Testing
- PRF, Curcuma Longa gel, extraction socket
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rania Farouk Mohamed Abdulmaguid
Unrestorable Dentition
Evaluation of Socket Preservation Using Autogenous Dentine Graft With Or Without Autologous Fibrin Glue
The aim of this interventional study is to investigate the dimensional changes in buccolingual alveolar ridge width in socket preservation using sticky dentin vs dentin graft alone The main question: is dentin graft mixed with…
- Trial name
- NCT06027528
- Testing
- dentin graft mixed with autologous fibrin glue, dentin graft
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Cleft, Orthodontic Space Closure
Gingival Cleft Development at Two Time Points of Canine Retraction
The goal of this split-mouth randomized controlled trial is to assess whether the timing of extraction space closure-early vs. delayed initiation-affects the incidence of gingival cleft development in orthodontic patients.
- Trial name
- NCT07210762
- Testing
- Early space closure, Delayed space closure
- Where
- Pakistan
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Bahria University
L-PRF, Dental Implants
Evaluation of the Effect of Leucocyte Platelet-Rich Fibrin (L-PRF) Technique Applied in Post-extraction Sockets Before Placement of Dental Implants
Aim of study: The application of L-PRF membrane in post-extraction sockets outmatches the use of a) allograft covered with a collagen fleece b) allograft combined with L-PRF membrane c) natural healing, with reference to bone…
- Conditions
- L-PRF, Dental Implants, Osseointegration, Alveolar Bone Grafting
- Trial name
- NCT07387913
- Testing
- Allograft and collagen membrane, Allograft and L-PRF membrane, L-PRF
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Hypercholesterolemia
The Effect Of Simvastatin On Bone Remodeling In Socket Of Mandibular Teeth
Simvastatin has been reported to promote osteoblastic activity and inhibit osteoclastic activity by enhancing the expression of BMP2.
- Trial name
- NCT01085149
- Testing
- Simvastatin
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Bone Injury
Salivary Bmp-2 Levels & Radiographic Measurement Of Bone Density at Extracted Tooth
Salivary Bmp-2 Levels \& Radiographic Measurement Of Bone Density were evaluated At Extracted Tooth Socket in patients With \& Without topical Application Of Simvastatin
- Trial name
- salivaryBMP2 (NCT05369091)
- Testing
- Simvastatin 10mg
- Where
- Pakistan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Postgraduate Medical Institute, Lahore
Extracting Own Teeth
Evaluation of Bone Behavior in Maxillary Post-extractive Sites Treated With Guided Bone Regeneration (G.B.R.) Techniques in Alveolar Socket Preservation (A.S.P.) Procedures With Different Autologous and Heterologous Biomaterials.
The maxillary bone atrophies from traumatic, pathological events or related to physiological bone loss after tooth extraction, promoting a decrease in bone volume (vertical-horizontal) which has always been a crucial challenge…
- Trial name
- NCT07269990
- Testing
- compare different types of biomaterials 4 months after application through the use of ASP compare different types of biomaterials 4 months after application through the use of ASP Group 2, Comparison of different types of biomaterials 4 months after application through the use of ASP, Comparison different types of biomaterials 4 months after application through the use of ASP
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Alveolar Socket Preservation
Clinical, Histological and Micro-computed Tomographic Evaluation of Neoformed Tissue in Post-extraction Sockets Covered With Platelet-rich Fibrin (PRF) Membrane: a Randomized Controlled Trial
The platelet-rich fibrin (PRF), belongs to a new generation of plasma concentrate with biomechanical processing simplified and without the need for handling blood biochemistry.
- Trial name
- NCT02300246
- Testing
- Platelet-Rich Fibrin
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Marcos de Oliveira Barceleiro
Dimensional Changes After Tooth Extraction, Tooth Extraaction
Alveolar Ridge Preservation Using Autogenous Whole Tooth Graft With 1 %Metformin :A Randomized Controlled Clinical Trial
This study describes a technique used to preserve the bone dimensions after the tooth extraction inorder to facilitate later on the dental implant placement
- Conditions
- Dimensional Changes After Tooth Extraction, Tooth Extraaction, Socket Preservation
- Trial name
- NCT07086859
- Testing
- TEST 1, Control
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Decayed Teeth
Effect of Bone Marrow Mononuclear Cell Layer Seeded on Platelet-rich Fibrin on an Alveolar Socket After Extraction
Bone marrow aspiration from maxillary tuberosity will be centrifuged to separate the bone marrow mononuclear cell layer using the density gradient separation method, then it will be seeded in a platelet-rich fibrin membrane and…
- Trial name
- NCT05465421
- Testing
- bone marrow aspiration from maxillary tuberosity and BMMNCs separation to be seeded on PRF and used for socket preservation
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Osteitis, Impacted Tooth
Effect of CGF on Frequency of Alveolar Osteitis Following Partially Erupted Mandibular Third Molar Surgery
The aim of this prospective study was to assess the effectiveness of concentrated growth factors (CGFs) in preventing the development of alveolar osteitis (AO) after the extraction of partially-erupted mandibular third molars.
- Trial name
- NCT04151147
- Testing
- Concentrated Growth Factor (Test group), Non-Concentrated Growth Factor (Control group)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ege University
Unrestorable Dentition, Post-Extraction Sockets
An Assessment of Bone Augmentation in Post-Extraction Sockets
When a tooth is extracted the ridge of bone that held the tooth in place begins to heal and over time new bone grows to fill the empty space left by the missing tooth.
- Trial name
- FMD-007 (NCT00641316)
- Testing
- AtraumaticTeeth Extraction, Atraumatic Teeth Extraction/Grafted Extraction Sockets
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Tooth Loss, Bone Loss, Alveolar
Immediate Implant Outcomes With and Without Bone Augmentation
To evaluate immediate implant placement feasibility and esthetic outcomes in severely damaged sockets that received simultaneously bone reconstruction (cortical bone shield) and implant placement versus intact sockets that needed…
- Conditions
- Tooth Loss, Bone Loss, Alveolar, Dental Diseases, Dental Trauma
- Trial name
- NCT05157009
- Testing
- implant placement
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Verdugo, Fernando, DDS
Alveolar Bone Resorption, Preserving the Alveolar Ridge
Radiographic Evaluation in Alveolar Preservation Using Platelet-rich Fibrin. Randomized Controlled Trial
This randomized controlled trial is designed to assess the use of platelet-rich fibrin (PRF), a biomaterial derived from a participant's own blood, in alveolar ridge preservation following premolar extraction for orthodontic…
- Trial name
- NCT06900036
- Testing
- Platelet-Rich Fibrin (PRF) Application for Alveolar Preservation
- Where
- Ecuador
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Universidad Católica de Cuenca