Clinical trials: Traumatic Injuries
Adult ALL, Post-traumatic Stress Disorder
Effects of an EMDR Intervention on Traumatic and Obsessive Symptoms
The Eye Movement Desensitization and Reprocessing Protocol (EMDR) was first developed by Francine Shapiro in 1987 and can be adapted for online and in presence administration.
- Conditions
- Adult ALL, Post-traumatic Stress Disorder, Obsessive-Compulsive Disorder, Disgust
- Trial name
- MDL (NCT06110702)
- Testing
- EMDR
- Where
- Italy
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Stress
Comparative Effectiveness of Stress Management
Many formerly homeless adults with chronic mental illness experience treatment resistant symptoms for which pharmaceutical agents and cognitive behavioral therapy are not effective.
- Trial name
- NCT03203902
- Testing
- Psychoeducation and Therapeutic Touch
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Columbia University
Traumatic Injury
Prevention of Injury in Military Settings Through the Use of Body Awareness.
The POSITION project aims to investigate the cognitive mechanism of postural body awareness as a risk factor for injury and as a target for a primary prevention strategy based on the Resource Optimization of Armed Forces (ROAF)…
- Trial name
- POSITION (NCT05451394)
- Testing
- ROAF, Active Comparator
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Substance-Related Disorders, Depression
Wraparound for High-risk Families with Substance Use Disorders: Examining Family, Child, and Parent Outcomes
The investigators propose a Hybrid Type 1 effectiveness-implementation quasi-experimental trial. Participants are drawn from two different communities contemporaneously.
- Conditions
- Substance-Related Disorders, Depression, Stress Disorders, Post-Traumatic, Child Abuse
- Trial name
- NCT04637581
- Testing
- Wraparound
- Where
- 4 sites in United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Posttraumatic Stress Disorder
The Role of Expectations in the Development of Intrusive Memories
In the experimental study, the well-established trauma film paradigm will be used to investigate the impact of expectations on the development of intrusive memories as a hallmark symptom of PTSD.
- Trial name
- NCT03950869
- Testing
- Positive Expectation Manipulation, Negative Expectation Manipulation
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
Concussion, Brain, Mild Traumatic Brain Injury
A Highly Portable Device for Assessment of Mild Traumatic Brain Injury in Deployed and Far-Forward Settings
The purpose of this study is to develop a highly portable, ruggedized diagnostic tool for concussion, EyeBOX Lens (EBLens), that can be utilized in deployed field and far-forward settings.
- Trial name
- NCT05527041
- Testing
- EyeBOX Lens (EBLens)
- Where
- United States
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Oculogica, Inc.
Concussion, Mild
Sex and Age Ultrasound Response to Differential Jugular Vein Pressure
Clinical trials have suggested that this device is effective in mitigating changes in brain structure and function in athlete populations.
- Trial name
- NCT03017937
- Testing
- Q-collar
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Traumatic Brain Injury, Parkinson's Disease
Imaging Biomarkers of Delayed Sequelae in Trauma Brain Injury
The purpose of this study is to learn if a new brain imaging technology called DaTscan can detect subtle changes in the brain that are similar to those seen in early Parkinson's disease (PD).
- Trial name
- NCT01516281
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Caregivers
Improving Outcomes for Care Partners of Persons With Traumatic Brain Injury
Care partners of persons with traumatic brain injury (TBI) are often faced with considerable physical and emotional stress resulting from their caregiver role.
- Trial name
- NCT04570930
- Testing
- Just-in-time adaptive intervention (JITAI), Control
- Where
- 2 sites in United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Brain Concussion, Brain Injuries
Screening Brain MRI in High School Football: Does the Guardian Cap Reduce the Risk of Traumatic Brain Injury
Screening Brain magnetic resonance imaging (MRI) with Fluid-attenuated Inversion Recovery (FLAIR) and Susceptibility Weighted Imaging (SWI) sequences will be performed pre and post season on high school football players.
- Conditions
- Brain Concussion, Brain Injuries, Diffuse Axonal Injury, Athletic Injuries
- Trial name
- NCT02757053
- Testing
- Guardian Cap
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Mosaic Life Care
Brain Injury Traumatic Mild, Concussion, Brain
Dual-task Assessment and Rehabilitation for Individuals With Residual Symptoms After mTBI
This research aims to develop an intervention that combines mTBI-specific motor and cognitive challenges into a progressive and challenging rehabilitation program.
- Trial name
- NCT03478059
- Testing
- Cognitive and Motor Dual-task Intervention
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Allina Health System
Complex Regional Pain Syndromes, Fibromyalgia
Virtual Environment Rehabilitation for Patients With Motor Neglect Trial
Motor neglect describes a loss of function without a loss of strength, reflexes or sensation. Motor neglect has been described in patients with traumatic brain injury, stroke and chronic pain conditions, e.g.
- Conditions
- Complex Regional Pain Syndromes, Fibromyalgia, Stroke, Traumatic Brain Injury
- Trial name
- VERMONT (NCT03887962)
- Testing
- Virtual Environment Biofeedback, Treadmill walking with no Virtual Environment Biofeedback
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Traumatic Knee Arthrotomy
Sensitivity Diagnosing Traumatic Knee Injuries With and Without Injection of Blue Dye Into the Knee Joint
The purpose of this study is to determine if adding blue dye improves the saline load test, which is a way to detect a traumatic intraarticular knee injury by injecting normal saline into the knee and looking for outflow through…
- Trial name
- NCT01073124
- Testing
- Saline Load Test
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Communication Disorder, Social
Roll for Intervention - TBI Group Treatment
Communication group intervention for individuals with Traumatic Brain Injury based on INSIGHT protocol (Keegan et al, 2020) with roll playing game focus
- Trial name
- NCT05517161
- Testing
- INSIGHT
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Moravian University
Mild Traumatic Brain Injury, Concussion, Mild
Neural Injury in Adolescents With Concussion
This study utilizes multimodal brain imaging to obtain quantitative biomarkers of brain injury and to improve understanding of the biological basis of brain pathology in adolescents with concussion.
- Conditions
- Mild Traumatic Brain Injury, Concussion, Mild, Acute Brain Injury
- Trial name
- NCT03011983
- Testing
- MEG, MRI, Neuropsychology assessment
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Gingival Recession, Gingival Abrasion
Evaluation of Gingival Fissures Associated With Soft and Medium Toothbrushes
Gingival fissures (GF) have been suggested as risk indicators for clinical attachment loss (CAL) and gingival recession, especially in free surfaces and in patients with low plaque scores.
- Conditions
- Gingival Recession, Gingival Abrasion, Wounds and Injuries
- Trial name
- NCT03367481
- Testing
- Toothbrush type
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Concussion
Innovative Concussion Prevention Device
Significant morbidity, mortality, and related costs are caused by traumatic brain injury (TBI). A simple, effective, and lightweight device worn by athletes or war fighters in the field, designed to mitigate TBI resulting from…
- Trial name
- NCT02901028
- Testing
- Laboratory testing, Blood and Urine Draws
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Stress, Emotional, Stress-related Mental Disorders
Effects of Parent-Adolescent Joint Interventions for Adolescents With Adverse Childhood Experiences
The study aims to examine the effectiveness of joint parent-adolescent intervention in improving the mental health outcomes of participants, specifically by reducing symptoms of depression, anxiety, and PTSD, as measured by the…
- Conditions
- Stress, Emotional, Stress-related Mental Disorders, Adverse Childhood Experiences
- Trial name
- EASY-PEP (NCT06619821)
- Testing
- Emotiaonl skill enhancement, PCE promotion, Psychoeducation
- Where
- 2 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Peking University
Post Traumatic Stress Disorder, Depression
CARE Study for Paramedics in Singapore
The purpose of this study is to compare the effectiveness of two different online education courses (Oxford-Online and Mind-Online) for preventing stress related conditions among paramedics who have been working during a period…
- Conditions
- Post Traumatic Stress Disorder, Depression, Anxiety Disorders and Symptoms, Burnout
- Trial name
- NCT07457801
- Testing
- Oxford-Online, Mind-Online
- Where
- Singapore
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Traumatic Dental Injuries
The Degree of Knowledge and Attitude of Egyptian Physicians Regarding Emergency Treatment of Traumatic Dental Injuries
This study intends to evaluate physicians' fundamental knowledge and attitude regarding the management of TDIs in Egypt. A convenience sample of physicians will be enrolled in this cross-sectional study, and they will be asked to…
- Trial name
- NCT06437275
- Testing
- Questionnaire for the degree of knowledge and attitude
- Where
- Egypt
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Cairo University
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