Clinical trials: Traumatic Injuries
Traumatic Brain Injury
Balance After Traumatic Brain Injury
A moderate traumatic brain injury (TBI) occurring in early or middle adulthood might have long-lasting effects on the brain that can accelerate the decline of physical and cognitive function in older age.
- Trial name
- NCT05714150
- Testing
- Complex Balance Tasks
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Brain Concussion
The s100β Levels in Patients With Mild Brain Injury.
Mild traumatic brain injury (TBI) accounts for the majority of TBI. At present, whether TBI has traumatic intracranial lession is mainly diagnosed by computed tomography (CT), while only 5% of mild TBI has positive CT results.
- Trial name
- NCT06131242
- Testing
- It is an observational study
- Volunteers
- 494 people, healthy volunteers welcome
- Sponsor
- Sumei Lu
Post Traumatic Stress Disorder, Childbirth Experience
"Connected Caesarean Section": Creating a Virtual Link Between Mothers and Their Infants to Improve Maternal Childbirth Experience: A Pilot Trial
One third of mothers rate their childbirth as traumatic. The prevalence of childbirth-related posttraumatic stress disorder (CB-PTSD) is of 4.7% and the prevalence of childbirth-related posttraumatic stress symptoms (CB-PTSS) of…
- Trial name
- e-motion-pilot (NCT05319665)
- Testing
- Head-mounted display
- Where
- Switzerland
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Mild Traumatic Brain Injury
HEAD Injury Serum Markers and Multi-modalities for Assessing Response to Trauma
The goal of HeadSMART II (HEAD injury Serum markers and Multi-modalities for Assessing Response to Trauma II) is to develop an In-Vitro Diagnostic, the BRAINBox TBI test, to aid in the diagnosis and prognosis of patients with…
- Trial name
- HeadSMART II (NCT04423198)
- Testing
- Cognitive Assessment, Patient Reported Neurological Outcome Assessments, Blood Draw
- Where
- 11 sites in United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- BRAINBox Solutions Inc
Stroke, Ischemic, Stroke Hemorrhagic
Exploring Accessible Beauty for Individuals With Upper Extremity Deficits
The purpose of this study is to investigate the accessibility of beauty products for individuals with upper extremity disabilities.
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Stroke (CVA) or TIA, Stroke, Acute
- Trial name
- NCT05945784
- Testing
- Use of Rare Beauty makeup products
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Sport Related Concussion
Pilot Study on the Correlation Between Accelerations Experienced
Concussion, or mild traumatic brain injury, accounts for 85% of brain injuries and is common in both professional and amateur sports.
- Trial name
- BIOIMPACT (NCT07507253)
- Testing
- Analyze correlations between the measurements of the variations in biomarkers with those obtained by an instrumented mouthguard measuring accelerations.
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Sys2Diag
Concussion, Brain
Comparing and Interactive Concussion Education Platform to Current Education Standards
Purpose: The purpose of this study is to evaluate the effectiveness of a theory- driven education platform to improve concussion-related norms and perceptions in an effort to improve student-athletes concussion-related…
- Trial name
- NCT04122274
- Testing
- NCAA education sheet, Decision-based interactive concussive education platform
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
PTSD - Post Traumatic Stress Disorder, Cognitive Dysfunction
Trifecta Research Study
This observational study evaluates the impact of Ibogaine-Magnesium (IM), 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT), Magnetic e-Resonance Therapy (MeRT), and Physiological Supplementation (PS) on posttraumatic stress disorder…
- Conditions
- PTSD - Post Traumatic Stress Disorder, Cognitive Dysfunction, Brain Injury, Depression - Major Depressive Disorder
- Trial name
- NCT07717866
- Testing
- Magnetic e-Resonance Therapy (MeRT), Ibogaine Hydrochloride with Magnesium Sulfate, 5-methoxy-N,N-dimethyltryptamine
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Axial Therapeutic Research
Post-Traumatic Stress Disorder
Effect of Propranolol on Preventing Posttraumatic Stress Disorder
This study will assess the effectiveness of taking propranolol soon after a traumatizing incident in reducing the incidence and severity of posttraumatic stress disorder in acutely traumatized individuals.
- Trial name
- NCT00158262
- Testing
- Propranolol
- Where
- 2 sites in United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Post Traumatic Stress Disorder
Observational Study of the Evaluation of Post Traumatic Stress Post Stroke
This prospective, observational, multicentre study evaluates the existence of Post-traumatic stress disorder following a stroke at 3 and 6 months after the management of the patient.
- Trial name
- SPTD (NCT04299841)
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- CHI MONT DE MARSAN ET PAYS DES SOURCES
Acute Stress Disorder, Anxiety
Safety & Efficacy of Intranasal Dexmedetomidine, Fentanyl & Midazolam in the Pediatric Emergency Room
The hypothesis is that intranasal dexmedetomidine will provide significantly more effective analgesia and anxiolysis for subjects undergoing a simple laceration repair when compared to either intranasal fentanyl or intranasal…
- Conditions
- Acute Stress Disorder, Anxiety, Pain
- Trial name
- NCT05057689
- Testing
- Intranasal Dexmedetomidine (4 mcg/kg), Intranasal Fentanyl (2 mcg/kg), Intranasal Midazolam (5 mg/kg)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Child Sexual Abuse, Post-Traumatic Stress Disorder, PTSD
Intensive Inpatient Trauma-Focused Cognitive Behavioral Therapy (II-TF-CBT) for Adolescents With PTSD Following Sexual Abuse
This study looks at a treatment program for children and teens who have post-traumatic stress disorder (PTSD) after sexual abuse. The program is called II-TF-CBT.
- Trial name
- NCT07732335
- Testing
- II-TF-CBT
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Chronic Pain, PTSD
Management of Chronic Pain and PTSD in Gulf War Veterans With tDCS+Prolonged Exposure
Gulf War Veterans (a DoD/VA defined service era corresponding to the first Gulf War under operations Desert Storm and Desert Shield 1990-1991), especially those who present with Post-Traumatic Stress Disorder (PTSD), are…
- Trial name
- NCT04236284
- Testing
- Home-based tDCS, Prolonged Exposure Therapy
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Concussion, Brain, Mild Traumatic Brain Injury
The Effects of Environmental Distractions on SCAT6 Outcomes
The purpose of this study is to assess the effects of visual and auditory distractions on SCAT5 scores. The study is designed to identify the effects of about 80 participants completing the SCAT5 in college-aged athletes.
- Trial name
- NCT05886400
- Testing
- SCAT6, Visual/ Auditory Distraction
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Indiana University
Brain Concussion, Reflex, Pupillary
Utility of Pupillary Metrics in Diagnosis and Management of Concussion in Children
The purpose of this study is to gather information and compare the potential use of pupillometry to identify concussions and post concussive syndrome with standard age appropriate assessments.
- Conditions
- Brain Concussion, Reflex, Pupillary, Post-Concussion Syndrome, Brain Injuries, Traumatic
- Trial name
- NCT04540445
- Testing
- Pupillary Assessment
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Orange County
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Head Injury, Face
Craneofacial Injuries in Rink Hockey Athletes
To collect the number of injuries that affect the face and head in rink hockey athletes prospectively during a regular season.
- Conditions
- Head Injury, Face, Concussion, Brain
- Trial name
- NCT05400551
- Where
- 2 sites in Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Oviedo
Chronic Subdural Hematoma
Randomized Controlled Trial Investigating Optimal Treatment for Chronic Subdural Hematoma
Setup of comparative trial The goal of this study is to determine whether one surgical treatment for chronic subdural hematoma is better than the other.
- Trial name
- NCT02655445
- Testing
- Mini-craniotomy, Twist Drill Craniostomy, Burr Hole Craniostomy
- Where
- Belgium
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Post-Traumatic Stress Disorder
Neural Correlates of Cognitive Rehabilitation in Post-Traumatic Stress Disorder (PTSD)
Post Traumatic Stress Disorder (PTSD) is an emotional disorder that can also lead to problems with attention and memory. Cognitive training has been successfully used to improve attention and processing speed in other patient…
- Trial name
- NCT00928941
- Testing
- cognitive training, video game
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Mental Disorders, Psychological Trauma
Hospital Cohort Survey of Public Health Post-attack of July 14, 2016
The terrorist attack on the ram truck, which occurred on 14 July 2016 on the Promenade des Anglais in Nice, involved a significant number of casualties in the civilian population: 86 dead including 10 children and adolescents…
- Trial name
- ECHOS (NCT03353805)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
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