Clinical trials: Upper Limb Disability
Acute Injury of Upper Extremity
Impact of Keeping a Personal Recovery Diary on Upper Extremity Disability
Primary null hypothesis: Keeping a personal diary has no effect on upper-extremity disability (assessed w/ PROMIS [Patient Reported Outcome Measurement Information System] upper extremity) 8 weeks after injury.
- Trial name
- NCT02361580
- Testing
- Diary
- Volunteers
- 9 people
- Sponsor
- Massachusetts General Hospital
Cerebral Palsy
Piloting Movement-to-Music With Arm-based Sprint-Intensity Interval Training Among Children With Physical Disabilities
This study is investigating the potential effects of a high-intensity home-exercise program among children with cerebral palsy. The program includes rhythmic movements to music that are adapted for wheelchair uses and…
- Trial name
- NCT05619211
- Testing
- Sprint-Intensity Interval Training with Telecoaching
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Multiple Sclerosis, Pathologic Processes
Upper Extremity Function in Multiple Sclerosis Patients With Advanced Disability Treated With Ocrevus
The investigators are measuring the effectiveness of Ocrevus™ in helping patients with hand or arm weakness, especially if posed by a more advanced MS patient than those included in the clinical trials.
- Conditions
- Multiple Sclerosis, Pathologic Processes, Demyelinating Diseases, Nervous System Diseases
- Trial name
- NCT03562975
- Testing
- Ocrelizumab
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of South Florida
Hunter Syndrome
A Study of Elaprase in Children and Adults With Hunter Syndrome (Mucopolysaccharidosis II) in India
The main aim of this study is to learn more about the safety profile of Elaprase in Indian children and adults with hunter syndrome.
- Trial name
- NCT05058391
- Testing
- Elaprase
- Where
- 5 sites in India
- Volunteers
- 5 people
- Sponsor
- Takeda
Stroke
New Tool to Enhance Post-stroke Upper Extremity Disability
Individuals with low socioeconomic status (SES) are more likely to have a stroke, more disabled at 3 months, and less likely to be independently ambulatory.
- Trial name
- NCT05277389
- Testing
- START - Startle Adjuvant Rehabilitation Therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Arizona State University
Hunter Syndrome
Study of Intrathecal Idursulfase-IT Administered in Conjunction With Elaprase® in Pediatric Patients With Hunter Syndrome and Early Cognitive Impairment
Study HGT-HIT-094 is a multicenter study designed to determine the effect on clinical parameters of neurodevelopmental status of monthly IT administration of idursulfase-IT 10 mg for 12 months in pediatric patients with Hunter…
- Trial name
- AIM-IT (NCT02055118)
- Testing
- idursulfase-IT, No IT treatment
- Where
- 9 sites in United States, Australia and 5 more
- Volunteers
- 58 people
- Sponsor
- Shire
Injuries, Injury Arm
Virtual Reality for Pain in Acute Orthopedic Injuries
The goal of this study is to pilot test a skills-based virtual reality (VR) for acute orthopedic injury. It will measure the feasibility, signals of improvement, exploratory pain mechanisms, and user experience of an established…
- Conditions
- Injuries, Injury Arm, Injury;Sports, Injury, Knee
- Trial name
- NCT05552430
- Testing
- RelieveVRx
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Massachusetts General Hospital
Stroke, Physical Disability
Concomitant Sensory Stimulation During Therapy to Enhance Hand Functional Recovery Post Stroke
The objective of this study is to determine if combining vibration with hand task practice is superior to hand task practice alone.
- Trial name
- NCT04569123
- Testing
- real stimulation, No stimulation
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Medical University of South Carolina
Distal Radius Fracture, Post Operative Pain Control
Single Shot vs Catheter Infraclavicular Brachial Plexus Block After Distal Radius Fracture Repair
The purpose of this study is to compare infraclavicular brachial plexus shot single shot block to continuous catheter nerve block done in adult patients who have under gone surgery to repair distal radius fractures.
- Trial name
- NCT02744352
- Testing
- 20ml bolus of 0.5% ropivicaine, 0.2% of ropivacaine at 8 milliliter/hour
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Pennsylvania
Arm Illness
The Effect of Questionnaire Content on Measures of Pain Intensity, Magnitude of Disability, and Symptoms of Depression in Patients With Arm Illness
The investigators plan a prospective randomized study to see whether negative questions affect measures of mood, pain, or disability. A total of 175 patients will participate at Massachusetts General Hospital.
- Trial name
- NCT02209259
- Testing
- PROMIS Upper Extremity Function, Pain intensity, PROMIS depression
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Massachusetts General Hospital
Stroke, Physical Disability
Neuroplasticity With Daily Use of a Sensorimotor Priming Vibration System to Improve Hand Function After Stroke
More than 4 million stroke survivors in the U.S. suffer from post-stroke sensorimotor hand disability, which is typically permanent and difficult to treat.
- Trial name
- NCT04026399
- Testing
- peripheral vibration stimulation, therapy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Medical University of South Carolina
Prader-Willi Syndrome
A Study of Oral ARD-101 in Patients With Prader-Willi Syndrome
A Phase 2, Single-Arm, Open-Label Study to Evaluate the Safety and Efficacy of ARD-101 in Patients with Prader-Willi Syndrome
- Trial name
- NCT05153434
- Testing
- ARD-101
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- Aardvark Therapeutics, Inc.
Breast Cancer, Chronic Pain
Reducing Pain and Disability After Breast Cancer Surgery
The purpose of this study is to determine if the combination of thoracic paravertebral block and multimodal analgesia will decrease chronic pain and arm morbidity in patients undergoing breast cancer surgery with lymph node…
- Trial name
- RELIeF (NCT01089933)
- Testing
- Thoracic Paravertebral Block (TPVB), Local Anesthetic
- Where
- Canada
- Volunteers
- 129 people
- Sponsor
- Ottawa Hospital Research Institute
Upper Extremity Injury, Sport Injury
Throwers Ten Exercises On Upper Extremity Function and Explosive Power in Wheelchair Basketball and Basketball Players
Basketball is a challenging sport that requires participants to demonstrate physical fitness and special athletic skills at high levels.
- Conditions
- Upper Extremity Injury, Sport Injury, Shoulder Pain, Muscle Weakness
- Trial name
- NCT04019990
- Testing
- The effect of throwers ten exercise programme on wheelchair basketball and ambulant basketball players
- Where
- Cyprus
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hacettepe University