Clinical trials: Urinary Infections
Urinary Tract Infection
Silver Alloyed Urinary Catheters and Incidence of Catheter Acquired Urinary Tract Infections (UTI)
This study is a single blinded (Outcome Assessors), multicenter randomized controlled study designed to investigate if a silver alloyed urinary catheter with antibacterial properties can reduce the incidence of catheter acquired…
- Trial name
- NCT01054690
- Testing
- Bactiguard Infection Protection (BIP) Cathter., Silicone Urinary Catheter
- Where
- 3 sites in Sweden
- Volunteers
- 511 people
- Sponsor
- Region Skane
Urinary Infections
Prevention of Catheter Associated Lower Urinary Infections Using the Oxys Indwelling Catheter
The safety and efficacy of a urinary catheter designed to prevent catheter associated urinary infections is studied.
- Trial name
- NCT02658903
- Testing
- Oxys Catheter, Covidien Mona-Therm Foley catheter
- Where
- Switzerland
- Volunteers
- 54 people
- Sponsor
- Oxys Medical AG
Fever Without Source
Impact of a PCT(Procalcitonin) Rapid Test -Based Approach on ATB (Antibiotics) Use in Children With Fever Without Source
Because a newly available point-of-care test may have real interest especially for children in the Emergency Department (ED) setting, by limiting painful and stressful venipunctures and decreasing the length of stay in the ED…
- Trial name
- DIAFEVER (NCT03607162)
- Testing
- DIAFEVER algorithm
- Where
- 26 sites in France, Switzerland
- Volunteers
- 4,928 people
- Sponsor
- Nantes University Hospital
Dehydration, Daily Fluid Intake
Robotics as a Useful Tool to Improve the Hydration of the Elderly
The aim of this clinical trial is to evaluate the effectiveness of a hydration educational program executed through a robot in comparison with the usual hydration program in terms of fluid intake and general health status of the…
- Conditions
- Dehydration, Daily Fluid Intake, Urinary Infections
- Trial name
- Hidroponent (NCT06520033)
- Testing
- humanoid robot, Usual care
- Where
- Spain
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Universitat de Lleida
Community-Acquired Infections, Respiratory Tract Infections
Validation of Vital Signs and Symptoms for the Diagnosis of Serious Infections in Children in the Paediatric A&E.
Validation of Vital Signs and Symptoms for the Diagnosis of Serious Infections in Acutely Ill Children in a High Prevalent Setting: The Paediatric Accidents \& Emergencies through prospective observational data collection…
- Conditions
- Community-Acquired Infections, Respiratory Tract Infections, Sepsis, Urinary Tract Infections
- Trial name
- ERNIE3 (NCT01396798)
- Where
- Belgium
- Volunteers
- 1,500 people
- Sponsor
- KU Leuven
Urinary Tract Infections
Comparative Study to Evaluate Efficacy and Safety of Gepotidacin to Nitrofurantoin in Treatment of Uncomplicated Urinary Tract Infection (UTI)
The study will be conducted to evaluate the therapeutic response (combined per participant microbiological and clinical response) of oral gepotidacin compared to oral nitrofurantoin for treatment of uncomplicated UTI (acute…
- Trial name
- NCT04187144
- Testing
- Gepotidacin, Nitrofurantoin
- Where
- 113 sites in United States, Australia and 4 more
- Volunteers
- 1,606 people
- Sponsor
- GlaxoSmithKline
Urinary Tract Infections, Catheter-Related Infections
Short-course Methenamine Hippurate for Prevention of Post-operative UTI
The investigators will determine the efficacy of an innovative short regimen of methenamine hippurate on prevention of post-operative UTI in patients requiring short-term catheterization after pelvic reconstructive surgery…
- Trial name
- NO-UTI (NCT02358993)
- Testing
- methenamine hippurate, Ciprofloxacin
- Where
- 4 sites in United States
- Volunteers
- 201 people
- Sponsor
- University of Pennsylvania
Diabetes Mellitus, Type 2
Post-authorisation Safety Study in Patients With Type 2 Diabetes to Assess the Risk of Liver Injury, Kidney Injury, Urinary Tract and Genital Infections, and Diabetic Ketoacidosis in Patients Treated With Empagliflozin, Compared to DPP-4 Inhibitors
Empagliflozin (Jardiance), a highly potent and selective inhibitor of the sodium-glucose cotransporter 2 (SGLT2), was approved in Europe in May 2014 for the treatment of type 2 diabetes mellitus (T2DM) to improve glycaemic…
- Trial name
- NCT02864914
- Testing
- Empagliflozin, DPP-4 inhibitors
- Where
- United Kingdom
- Volunteers
- 333,580 people
- Sponsor
- Boehringer Ingelheim
Urinary Tract Infections
Urinary Tract Infections in Older Persons Admitted to a Psychogeriatric Ward
Urinary tract infections are one of the most common types of infections in older persons. The general aim of this study is to improve the epidemiological knowledge and develop a better diagnostic algorithm for urinary tract…
- Trial name
- UTI_UCP (NCT02368847)
- Testing
- Diagnostic tests
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Uncomplicated Urinary Tract Infection, Patient With Uncomplicated UTI
Effectiveness of Visual Storytelling Intervention on Antibiotic Adherence in UTI Patients
This study aims to evaluate the effectiveness of a visual storytelling intervention in improving antibiotic adherence among adults with urinary tract infections (UTIs).
- Trial name
- ABR UTI (NCT06885658)
- Testing
- Visual Storytelling Intervention for Antibiotic Adherence
- Where
- Pakistan
- Volunteers
- 358 people
- Sponsor
- Xi'an Jiaotong University
Kidney Stone
The Interplay Between Oxalate, Immunity and Infection
This study consists of having subjects, those with calcium oxalate kidney stones as well as healthy controls, consume low and oxalate enriched diets to investigate the role of oxalate on crystalluria (the presence of crystals in…
- Trial name
- NCT04605055
- Testing
- Low Oxalate Diet, High Oxalate Diet
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Lower Urinary Tract Infection
Clinical Study to Evaluate the Efficacy of the Dietary Supplement UROMANNOSA® in Women With Recurrent Lower Urinary Tract Infections
To analyze the clinical impact of a food supplement composed of D Mannose, cranberry extract (Cran-max) and Vitamin D3 in the prevention of recurrent lower urinary tract infections (UTI)
- Trial name
- NCT04880343
- Testing
- Group (A), Group (B)
- Where
- Spain
- Volunteers
- 108 people
- Sponsor
- Carmen Gonzalez Enguita
Woman Aged 18 to 65
Prevention of Cystitis.
3436/5000 Urinary tract infections are a real public health issue. The frequency of these infections in France is estimated between 6 and 8 million in primary care (1) which represents 15% of antibiotics prescribed in primary…
- Trial name
- NCT03744338
- Testing
- questionnaire
- Where
- France
- Volunteers
- 773 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Infection, Pneumonia
To Evaluate the Treatment Effect of an Anti-Infective Agent for Different Kinds of Infections (0826-052)
To collect clinical response data with the use of ertapenem in approved indications.
- Conditions
- Infection, Pneumonia, Urinary Tract Infection
- Trial name
- NCT00398099
- Testing
- MK0826, ertapenem sodium / Duration of Treatment: 14 Days
- Volunteers
- 30 people
- Sponsor
- Merck Sharp & Dohme LLC
Urinary Tract Infections, Acute Pyelonephritis
Safety and Efficacy Study of Cefepime/VNRX-5133 in Patients With Complicated Urinary Tract Infections
This study will assess the safety and efficacy of cefepime/VNRX-5133 compared with meropenem in both eradication of bacteria and in symptomatic response in patients with cUTIs.
- Trial name
- CERTAIN-1 (NCT03840148)
- Testing
- Cefepime/VNRX-5133 (taniborbactam), Meropenem
- Where
- 78 sites in United States, Argentina and 13 more
- Volunteers
- 661 people
- Sponsor
- Venatorx Pharmaceuticals, Inc.
Urinary Tract Infections
Finafloxacin 300 mg Twice a Day (b.i.d.) Versus Ciprofloxacin 250 mg Twice a Day (b.i.d) in Patients With Lower Uncomplicated UTI (uUTI)
To compare the bacteriological eradication rates of Finafloxacin and Ciprofloxacin in female patients with uUTI.
- Trial name
- FLUT (NCT00722735)
- Testing
- Finafloxacin, Ciprofloxacin
- Where
- 2 sites in Germany, Singapore
- Volunteers
- 36 people
- Sponsor
- MerLion Pharmaceuticals GmbH
Urinary Tract Infections
Phase II Proof of Concept Study in Uncomplicated UTI
A study of the efficacy and safety of MPC-SHRC for the relief of symptoms associated with uncomplicated urinary tract infections.
- Trial name
- NCT03129295
- Testing
- MPC-SHRC
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Mission Pharmacal
Urinary Symptoms, Systemic Sclerosis
Lower Urinary Tract Symptoms in Systemic Sclerosis
Urinary symptoms must be frequent in Scleroderma. In one hand, mobility limitation by joint stiffness and skin sclerosis, forced diuresis due to heart involvement (cardiomyopathy or pulmonary hypertension), diuretics use and…
- Trial name
- NCT01971294
- Where
- 4 sites in France, Italy and 1 more
- Volunteers
- 334 people
- Sponsor
- University Hospital, Geneva
Recurrent Urinary Tract Infections
Probiotic Supplement for Recurrent UTIs in Healthy Women (L. Plantarum, L. Rhamnosus, B. Lactis)
This randomized, double-blind, placebo-controlled trial will evaluate the efficacy of a probiotic food supplement containing Lactiplantibacillus plantarum PBS067, Lacticaseibacillus rhamnosus LRH020, and Bifidobacterium animalis…
- Trial name
- BIO-RUTI-26 (NCT07884929)
- Testing
- Dietary Supplement containing probiotics
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Synbalance S.r.l.
Healthcare-associated Pneumonia (HCAP), Bloodstream Infections (BSI)
Study of Cefiderocol (S-649266) or Best Available Therapy for the Treatment of Severe Infections Caused by Carbapenem-resistant Gram-negative Pathogens
This study is designed to provide evidence of efficacy of cefiderocol in the treatment of serious infections in adult patients caused by carbapenem-resistant Gram-negative pathogens.
- Conditions
- Healthcare-associated Pneumonia (HCAP), Bloodstream Infections (BSI), Hospital Acquired Pneumonia (HAP), Complicated Urinary Tract Infection (cUTI)
- Trial name
- CREDIBLE - CR (NCT02714595)
- Testing
- Cefiderocol, Best Available Therapy
- Where
- 85 sites in United States, Brazil and 14 more
- Volunteers
- 152 people
- Sponsor
- Shionogi
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