Clinical trials: Urologic Diseases
Hyperparathyroidism, Secondary, Kidney Failure, Chronic
A Phase 2 Study of an Oral Vitamin D Compound (DP001) in Secondary Hyperparathyroidism in Patients on Hemodialysis
The goal of this study is to test a new vitamin D compound for its ability to reduce parathyroid hormone levels in patients who are on hemodialysis.
- Trial name
- 2MD-7H-2B (NCT01922843)
- Testing
- DP001 softgel capsules
- Where
- 14 sites in United States
- Volunteers
- 62 people
- Sponsor
- Deltanoid Pharmaceuticals
Kidney Stone
Fluid Intake Application to Reduce Kidney Stone Risks
The purpose of this investigation is to prospectively evaluate the benefit of different methods of educating patients regarding their fluid intake through a readily available daily cellular phone application to improve overall…
- Trial name
- NCT01928108
- Testing
- iPhone Application, Android Application
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of North Carolina, Chapel Hill
Lupus Nephritis
Effect of Mesenchymal Stem Cell Transplantation for Lupus Nephritis
Mesenchymal Stem Cell (MSC) has been shown to have immunosuppressive and repairing properties. Manifestations of systemic lupus eryhematosus(SLE) may in most patients be ameliorated with medications that suppress the immune…
- Trial name
- NCT00659217
- Testing
- mesenchymal stem cell
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Organ Transplant Institute, China
Over-Active Bladder
VESIcare For Improving OAB Symptoms in Patients Undergoing IGRT of the Prostate
The purpose of this study is to determine if Vesicare (Solifenacin succinate) is effective in treating over-active bladder symptoms during radiation therapy of the prostate.
- Trial name
- NCT01777217
- Testing
- Solifenacin succinate
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Advanced Research Network
End-Stage Renal Disease
Heparin-Free Chronic HemoDialysis Assessment
Intermittent hemodialysis is a complex technique which requires careful monitoring of anticoagulation levels to prevent clotting and reduce the risk of bleeding complications.
- Trial name
- HepFreeHD (NCT06224140)
- Testing
- Heparin Anticoagulation, Regional Anticoagulation Procedure (RAP)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Urologic Cancer, Thrombosis
Thrombembolism After Robot- Assisted Surgery in Urology
Cancer patients have an increased risk of perioperative complications undergoing surgery procedures. Postoperative complications caused by thrombembolic events after robot- assisted surgery in major urological procedures have…
- Conditions
- Urologic Cancer, Thrombosis, Embolism, Surgery--Complications
- Trial name
- NCT04796740
- Where
- Germany
- Volunteers
- 450 people
- Sponsor
- University Hospital Schleswig-Holstein
Chronic Kidney Disease
Study to Evaluate the Prospective Payment System
To describe trends in treatment patterns of Small Dialysis Organizations (SDOs) prior to and during the implementation of the Centers for Medicare and Medicaid Services' (CMS') policy [End Stage Renal Disease (ESRD) Prospective…
- Trial name
- STEPPS™ (NCT01717989)
- Where
- 41 sites in United States, Puerto Rico
- Volunteers
- 2,248 people
- Sponsor
- Amgen
Urothelial Carcinoma, Bladder Cancer
Urothelial Cancer Tumor Bio-markers and Physical-spectroscopic Characteristic
Our multicenter observational study is a non-profit prospective study. The study was born from the Amplitude Project, which comprise the SOD of Minimally Invasive Robotic Urological Surgery and Renal Transplants of AOU Careggi…
- Conditions
- Urothelial Carcinoma, Bladder Cancer, Urothelial Neoplasm, Urothelial Carcinoma Bladder
- Trial name
- NCT04770974
- Testing
- Biomarkers and proteomics
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- University of Florence
Chronic Kidney Disease
Impact of Specialised Renal Care in Patients With Chronic Kidney Disease
This is a prospective randomised trial studying patients with stage 3 to 5 chronic kidney disease (CKD) in order to determine the impact of specialised care by nephrologists compared to guidelines-directed management by primary…
- Trial name
- IMPLICATE (NCT00929760)
- Testing
- specialised renal care
- Where
- Switzerland
- Volunteers
- 242 people
- Sponsor
- Patrick Saudan
End Stage Renal Disease
The 2-minute Walk Test in Hemodialysis Patients
Walking tests are widely used to assess functional capacity in different populations because of their ease of administration, interpretability and representativeness of activities of daily living.The aim of our study was to…
- Trial name
- NCT06650215
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Primary IgA Nephropathy
The Effect of Nefecon® in Patients With Primary IgA Nephropathy at Risk of Developing End-stage Renal Disease
The objective of the study is to evaluate efficacy and safety of two different doses of NEFECON in the treatment of patients with primary IgA nephropathy (IgAN) at risk of developing end-stage renal disease, under rigorous blood…
- Trial name
- NEFIGAN (NCT01738035)
- Testing
- NEFECON
- Where
- 58 sites in Belgium, Czechia and 8 more
- Volunteers
- 150 people
- Sponsor
- Calliditas Therapeutics AB
Acute-On-Chronic Liver Failure, Ascites
Efficacy, Safety and Tolerability of VS-01 in Adult Patients With Acute-on-Chronic Liver Failure and Ascites (UNVEIL-IT)®
A Phase 2, multi-center, randomized, controlled, open-label study to evaluate the effects of the intraperitoneal, liposomal formulation VS-01 in patients with an acute episode of hepatic and/or extrahepatic organ dysfunctions and…
- Trial name
- NCT05900050
- Testing
- VS-01 on top of SOC, SOC (Control Group)
- Where
- 26 sites in United States, Belgium and 5 more
- Volunteers
- 15 people
- Sponsor
- Genfit
Acute Kidney Injury
Differential Adaptation of Renal Function in Intense Physical Exercise
In recent years there has been a significant increase in the number of participants in high intensity and duration sports events.
- Trial name
- NCT04929418
- Testing
- 10 km continuous running, 1.5 km continuous swimming
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital Clínico Universitario de Valladolid
Renal Artery Obstruction
Gadobutrol Enhanced MRA of the Renal Arteries
Subjects referred for a routine CTA (computed tomography angiography) or MRA (magnetic resonance angiography) will be invited to participate in the study and subjects will be involved in the study for between 2 and 12 days.
- Trial name
- GRAMS (NCT01344460)
- Testing
- Gadobutrol (Gadovist, BAY86-4875)
- Where
- 70 sites in United States, Argentina and 11 more
- Volunteers
- 317 people
- Sponsor
- Bayer
Chronic Renal Failure
Outcome of Arterio-venous Fistula for Adult Hemodialysis Patients in Assiut Governorate
identification of the factors that affect the outcome of arteriovenous fistula in chronic renal failure patients that newly established regular dialysis in Assiut Governorate 1.
- Trial name
- NCT03397381
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Chronic Renal Disease
Nephrotoxicity of Iopamidol Versus Iodixanol in High-Risk Patients
The purpose of this study is to compare the incidence of contrast-induced nephropathy (CIN) following the administration of iopamidol-370 (Iopamiro-370) and iodixanol-320 (Visipaque 320) in patients with chronic kidney disease…
- Trial name
- NEIHR (NCT01402219)
- Testing
- Iopamidol injection 76%, iodixanol
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Guangdong Provincial People's Hospital
Infection Due to Indwelling Urinary Catheter
Effect of CAUTI Prevention Alert - A Randomized Control Trial
This study proposes to expand upon previous research by studying the effects of a urinary-catheter removal alert on duration of urinary catheter use and frequency of CAUTIs with a large, randomized controlled trial within a…
- Trial name
- NCT02054065
- Testing
- CAUTI Decision Support
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Montefiore Medical Center
Diabetic Kidney Disease (DKD)
Vascular Endothelial Growth Factor-B (VEGF-B) Blockade With the Monoclonal Antibody CSL346 in Subjects With Diabetic Kidney Disease
This phase 2a, double-blind, randomized, placebo-controlled study will assess the efficacy, safety, tolerability, and pharmacokinetics (PK), of repeat doses of CSL346 in subjects with diabetic kidney disease (DKD) and albuminuria…
- Trial name
- NCT04419467
- Testing
- CSL346
- Where
- 37 sites in United States, Australia and 4 more
- Volunteers
- 114 people
- Sponsor
- CSL Behring
Hospital Infection, Urinary Tract Infections
The Global Prevalence of Infections in Urology Study
Urology departments from all over the world are invited to join the Global Prevalence Study on Infections in Urology (GPIU-study) and the GPIU Prostate Biopsy Side Study.
- Trial name
- GPIU (NCT03665467)
- Where
- 4 sites in Germany, Hungary and 2 more
- Volunteers
- 2,000 people
- Sponsor
- European Association of Urology Research Foundation
Bladder Cancer
Multimodal Rehabilitation Program to Bladder Cancer Patients
The incidence of bladder cancer is increasing. Denmark have approximately 1800 incidence per year. The disease is most frequently in males above the age of 70 years.
- Trial name
- MRPBC (NCT01329107)
- Testing
- Multimodal Intervention
- Where
- 2 sites in Denmark
- Volunteers
- 129 people
- Sponsor
- University of Aarhus
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