Clinical trials: Vaccine Uptake
Immunization, Vaccination
The STOP-HPV Trial 1: Communication Intervention
Most adolescents who receive human papillomavirus (HPV) vaccine are vaccinated in pediatric practices, yet missed opportunities (MOs) for HPV vaccination occur often and lead to low HPV vaccination rates.
- Trial name
- STOP-HPV (NCT03599557)
- Testing
- STOP-HPV communication intervention
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Covid-19 Vaccination
Effect of Messaging on Pragmatic Outcomes Within an Integrated Healthcare System
COVID-19 vaccination among patients at high risk for severe disease has declined in the United States since 2022. Prior research, including discrete choice experiments (DCEs), has demonstrated that vaccine preferences are…
- Trial name
- EMPOWeR (NCT07838038)
- Testing
- Vaccine choice message, Vaccine choice + platform-framed message, Vaccine choice + HCP trust-framed message
- Where
- United States
- Volunteers
- 1,300,000 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
COVID-19
Conversation With Family Doctor to Increase COVID-19 Vaccine Uptake
The investigators will randomise individuals from family doctors' lists of patients that are at risk of severe Coronavirus Disease 2019 (COVID-19), and that are not registered as having taken the vaccine against the disease.
- Trial name
- NCT05207137
- Testing
- Telephone call about vaccination
- Where
- Norway
- Volunteers
- 654 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
Influenza, Infectious Disease
Brief Influenza Vaccine Education to Pregnant Women
The investigators will conduct a brief educational intervention to pregnant women who have not yet received the influenza vaccine in this pregnancy to improve the uptake of seasonal influenza vaccine.
- Conditions
- Influenza, Infectious Disease, Pregnancy
- Trial name
- NCT01772901
- Testing
- Influenza Vaccine Intervention
- Where
- 4 sites in Hong Kong
- Volunteers
- 321 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Influenza, Behavior and Behavior Mechanisms
Nationwide Utilization of Danish Government Electronic Letter System for Confirming the Effectiveness of Behavioral Nudges in Increasing InFLUenza Vaccine Uptake Among Older Adults
In randomized clinical trials and observational studies, influenza vaccination has been shown to be effective in reducing influenza-related illness, hospitalizations, cardiovascular events, and mortality in select populations.
- Trial name
- NUDGE-FLU-2 (NCT06030726)
- Testing
- Behavioral Economic Principles
- Where
- Denmark
- Volunteers
- 881,373 people, healthy volunteers welcome
- Sponsor
- Tor Biering-Sørensen
COVID-19 Vaccination
A Multicomponent Clinic-based Intervention to Promote COVID-19 Vaccine Intention and Uptake Among Diverse Youth and Adolescents
The goal of this study is to refine and test CONFIDENCE, a multi-component clinic-based intervention in pediatric or family practice clinical settings.
- Trial name
- CONFIDENCE (NCT05722652)
- Testing
- CONFIDENCE
- Where
- United States
- Volunteers
- 667 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
COVID-19
Can Doctors Reduce COVID-19 Misinformation and Increase Vaccine Uptake in Ghana? A Cluster-randomised Controlled Trial
Whilst Ghana was one of the first countries to start vaccinating its population against COVID-19, less than 30% of the population was fully vaccinated at the end of 2022.
- Trial name
- NCT06191211
- Testing
- Motivational Interviewing, AIMS, Facility engagement
- Where
- Ghana
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- London School of Economics and Political Science
Cervical Cancer
Delivery, Uptake and Acceptability of HPV Vaccination in Tanzanian Girls
The aims of this study are: 1. To determine feasibility of a school-based human papillomavirus (HPV) vaccination programme in Tanzania. 2.
- Trial name
- NCT01173900
- Testing
- Gardasil® HPV vaccine
- Where
- Tanzania
- Volunteers
- 5,532 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
HPV
Multi-level School-based Intervention to Improve HPV Vaccine Uptake and Completion in South Africa
Human Papillomavirus (HPV) is the most common sexually transmitted infection globally, and is causally linked to cervical, anogenital, and oropharyngeal cancers.
- Trial name
- NCT05919901
- Testing
- HPV Vaccine Communication Strategy
- Where
- South Africa
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Cervical Cancer Screening, Vaccination Uptake
Characteristics of Human Papillomavirus (HPV) Infections and HPV Vaccine Attitudes Among Slovenian Women After the Introduction of HPV Vaccination
Cervical cancer (CC), primarily caused by persistent infection with high-risk human papillomavirus (HPV) types, remains a significant public health issue.
- Trial name
- NCT06995157
- Testing
- Offering HPV vaccine
- Where
- Slovenia
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Vaccination
Can Stories Encourage the Elderly to Vaccinate? Combining Viewer-tailored Personal Narrative Videos With Informational Videos to Improve Vaccine Uptake Among Older Adults
This study will compare the use of informational videos only, personal story videos only, and the combination of both, to see which is most effective in increasing vaccination among older adults.
- Trial name
- NCT06890403
- Testing
- Informational Animation Video, Personal Narrative Video
- Where
- United States
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Vaccine Confidence, Adolescent Vaccination
Tailored Vaccine Messaging for Parents/Caregivers of Adolescents
his study will evaluate whether tailored vaccine messaging improves vaccination-related outcomes among parents and caregivers of adolescents.
- Conditions
- Vaccine Confidence, Adolescent Vaccination, Vaccine Uptake
- Trial name
- VACCINE-WEST (NCT07878442)
- Testing
- Tailored Vaccine Messaging, Standard Vaccine Message
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Utah
COVID-19 Vaccines, Telemedicine
Improving Pediatric COVID-19 Vaccine Uptake Using an mHealth Tool
This study will determine the effectiveness of a vaccine communication mobile health app on parental decisions to vaccinate their children against coronavirus disease 2019 (COVID-19).
- Conditions
- COVID-19 Vaccines, Telemedicine, Vaccine Hesitancy, Pediatric ALL
- Trial name
- MoVeUP (NCT05386355)
- Testing
- COVID-19 Vaccine Uptake App, General Health App
- Where
- 15 sites in United States
- Volunteers
- 1,934 people, healthy volunteers welcome
- Sponsor
- IDeA States Pediatric Clinical Trials Network
Influenza Vaccination
PROmotion of FLU Vaccine Uptake in the Emergency Department - PROFLUVAXED
The goal of this research is to increase influenza vaccine acceptance and uptake in vulnerable populations whose primary (and often only) health care access occurs in emergency departments (ED Usual Source of Care Patients).
- Trial name
- PROFLUVAXED (NCT05836818)
- Testing
- Question (Q), Messaging (M)
- Where
- 8 sites in United States
- Volunteers
- 776 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
COVID-19, Vaccine Uptake
Addressing Vaccine Hesitancy and Increasing COVID-19 Vaccine Uptake Among African American Young Adults in the South
The study staff will conduct a hybrid type 1 effectiveness implementation 2-arm trail with 360 Black young adults from Alabama, Georgia, and North Carolina.
- Trial name
- NCT05490329
- Testing
- Tough Talks COVID
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Florida State University
Stroke, Influenza Human
Vaccination Nudges From Pharmacists
The goal of this individual-level pragmatic randomized policy trial is to learn about the impact of behavioural nudges via mailed letters on increasing influenza and travel vaccination uptake in Alberta, Canada.
- Conditions
- Stroke, Influenza Human, Influenza Vaccines, Health Behavior Change
- Trial name
- NCT07161739
- Testing
- Behavioural Nudge (Influenza Risk Reduction), Behavioural Nudge (Travel Vaccination Benefit)
- Where
- Canada
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Influenza, Human
Impact of Patient Education on Influenza Vaccine Uptake Among Community-dwelling Chinese Elderly
The purpose of this study is to test the effectiveness of brief face-to-face patient education in increasing uptake of influenza vaccine among Chinese elderly in the community.
- Trial name
- NCT02741843
- Testing
- Patient Education
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Covid19, Vaccine Refusal
VEText Message Framing and Covid-19 Vaccine Uptake Among at Risk Veterans
This is a prospective, randomized controlled trial that will evaluate the effectiveness of two different targeted outreach interventions aimed at increasing Covid-19 vaccine uptake.
- Trial name
- VEText (NCT04805931)
- Testing
- Behavioral economics
- Where
- United States
- Volunteers
- 4,311 people, healthy volunteers welcome
- Sponsor
- VA Puget Sound Health Care System
Human Papillomavirus Vaccination, Cervical Cancer Prevention
Integrating HPV Education Into School Health Programs in Cambodia and Kenya
The Clinton Health Access Initiative conducted a mixed-methods, school-based interventional study in Cambodia and Kenya to evaluate whether integrating age-appropriate human papillomavirus (HPV) education into existing school…
- Trial name
- NCT07784283
- Testing
- Integrated HPV Education
- Where
- 5 sites in Cambodia, Kenya
- Volunteers
- 9,054 people, healthy volunteers welcome
- Sponsor
- Clinton Health Access Initiative Inc.
Influenza Vaccine, Healthcare Workers
Nudge and Motivational Interviewing Interventions to Improve Influenza Vaccine Uptake Among Healthcare Workers in China
The goal of this clinical trial is to learn if nudge-based interventions and motivational interviewing work to improve influenza vaccination uptake among healthcare workers in China.
- Trial name
- NCT07157163
- Testing
- Phase 1: standardized nudge messages, Phase 1: personalized nudge messages + chatbot, Phase 2: motivational Interviewing
- Volunteers
- 4,050 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention, China