Clinical trials: Vaginal Delivery
Normal Vaginal Delivery
Oral Misoprostol Solution in Comparison to Vaginal Misoprostol in Induction of Labor
Induction of labour at term is a common obstetric intervention. Induction of labour is the artificial initiation of labour before its spontaneous onset for the purpose of delivery of the fetoplacental unit using mechanical or…
- Trial name
- NCT03863392
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
HIV Infections
Safety and Pharmacokinetic Trial in Healthy HIV-Negative Women to Assess the Delivery of Dapivirine From a Vaginal Ring
The proposed study is a single center, double-blind placebo-controlled trial to assess the safety and tolerability of the dapivirine ring as compared to a placebo ring when inserted for 28 days in 16 healthy, HIV-negative women.
- Trial name
- NCT02920827
- Testing
- Dapivirine Vaginal Ring
- Where
- Belgium
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- International Partnership for Microbicides, Inc.
Focus is on Healthy Subjects
Vaginal Detection of Orally Delivered Probiotic Strains in Healthy Women
The purpose of the present study is to obtain more information on the transit of orally ingested probiotics to the vagina.
- Trial name
- VSS2 (NCT07246161)
- Testing
- Probiotic Formula 1, Probiotic Formula 2, Probiotic Formula 3
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Prolonged Labour
Can Ultrasound Predict Labor Outcome in Operative Vaginal Deliveries?
To assess whether ultrasound methods can predict outcome of operative vaginal deliveries in nulliparous women at term with singleton pregnancies and prolonged second stage of labor.
- Trial name
- NCT01878591
- Where
- Norway
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Helse Stavanger HF
Maternal Care for Other Abnormalities of Cervix
Maternal Consequences of Membrane Stripping
This study aims to investigate the maternal effects of membrane stripping during vaginal birth. This study was designed as an experimental case-control study.
- Trial name
- NCT06373250
- Testing
- Membrane stripping group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Behavior, Perceptions
The Effects of Sımulatıon Used in Vagınal Chıldbırth on Malpractıce Tendency And Perceptıons of Care Behavıors
H1a: The simulation-based training used to provide delivery skills have an effect on malpractice trends of midwifery students. H1b: The simulation-based training used to provide delivery skills have an effect on midwifery…
- Trial name
- NCT04656574
- Testing
- Simulation-based training
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Aysegul Durmaz
Full Term Singleton Pregnancy
Demonstration of a New Device to Measure the Force of Delivering a Baby
This study is an observational study to prove that a new device, which measures the force of delivering a baby, (US patent 6,684,165) functions as described in the patent. This is the first time this has been used with patients.
- Trial name
- NCT00964444
- Testing
- Peisner device
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pinnacle Health System
Vaginal Laceration During Delivery
The PAIN (Pelvic Area Injection for Numbness) Study
Postpartum pain can interfere with patient's ability to care for themselves, and their newborn, and untreated pain is associated with risk of greater opioid use, postpartum depression, and development of persistent pain.
- Trial name
- PAIN (NCT05972681)
- Testing
- Bupivacaine, Epinephrine
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Other Specified Complications of Labor and Delivery
Vaginal Delivery Debrief Checklist to Improve Team Communication
This study is to determine if using a standardized debrief checklist after vaginal delivery improves communication between the vaginal delivery health care team members and if using the checklist increases a sense of enhanced…
- Trial name
- VDD (NCT01822158)
- Testing
- Vaginal Delivery Debrief Checklist
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Providence Health & Services
Birth, First, Experience, Life
The Effect of Focus on Vaginal Examination Experience and Pain Level: a Randomized Controlled Trial
Vaginal examination contains many negative emotions such as pain, fear, stress, and discomfort for women. When the literature was examined, no study was found in which the focus method was used to reduce or eliminate the feelings…
- Conditions
- Birth, First, Experience, Life, Pain
- Trial name
- NCT05471219
- Testing
- Primiparous pregnant women who will undergo vaginal examination by focusing on visual traces
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Dilek Yigit Vural
Trial of Labor After Cesarean, Vaginal Birth After Cesarean
The Effectiveness and Safety of the Trial of Labor in Full Term Pregnant Women With Cesarean Section After Spontaneous Labor
This study is a multi-center, prospective, observational clinical trial study. 510 full-term pregnant women will be enrolled as subjects, and the ratio of eligible subjects in the two groups is 1:1.
- Conditions
- Trial of Labor After Cesarean, Vaginal Birth After Cesarean, Spontaneous Labor
- Trial name
- NCT05215041
- Testing
- Non intervention
- Where
- China
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Episiotomy Wound, Anemia
Use of Tranexamic Acid After Vaginal Delivery with Episiotomy a RCT Placebo Control Trail
The objective of this study is to assess the effect of TA treatment on decline in Hb levels following vaginal delivery with an episiotomy, compared to a control group not receiving TA.
- Conditions
- Episiotomy Wound, Anemia, Early Postpartum Hemorrhage, Hemoglobin
- Trial name
- NCT05448456
- Testing
- Tranexamic acid
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assuta Ashdod Hospital
Vaginosis, Bacterial, Abortion, Spontaneous
Bacterial Vaginosis Screening and Treatment to Reduce Infective Complications, Abortion and Preterm Delivery
To determine whether screening of pregnant women with history of previous preterm delivery or with premature contractions for bacterial vaginosis using VS-SENSE, and treatment of positive women will reduce the risk of spontaneous…
- Conditions
- Vaginosis, Bacterial, Abortion, Spontaneous, Premature Birth
- Trial name
- NCT00491270
- Testing
- VS Sense
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Perineal Trauma
Effect of Nursing Care Bundle Upon Perineal Trauma Reduction and Birth Outcomes During Vaginal Birth
This study aimed to evaluate the effect of implementing a nursing care bundle upon perineal trauma reduction and birth outcomes during vaginal birth. A quasi-experimental design was employed.
- Trial name
- NCT07505524
- Testing
- nursing care bundle
- Where
- Palestinian Territories
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Al-Quds University
Pelvic Floor Disorders
Pelvic Floor Function After Vaginal and Cesarean Delivery Among Egyptian Women
A cross sectional study for assessment of pelvic floor functions after 6 months to 4 years after normal vaginal delivery or Cesarean section
- Trial name
- NCT03126604
- Testing
- female sexual function index
- Where
- Egypt
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Cairo University
Labor Pain, Comfort
Using Wet Towel During Labor
The goal of this clinical trial is to learn whether the wet towel method applied during the first stage of labor can reduce labor pain and anxiety and improve childbirth comfort in first-time mothers.
- Conditions
- Labor Pain, Comfort, Labor Anxiety
- Trial name
- NCT07808840
- Testing
- Wet Towel
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Low Back Pain, Pregnancy
The Effect of Kinesio Taping During Labor on Low Back Pain, Vaginal Birth Self-Efficacy, Postpartum Comfort Perception, and Newborn Apgar Scores
The Kinesio Taping® technique and Kinesio Tex® tape were invented by Japanese chiropractor and acupuncturist Dr. in 1973. Developed by Kenzo Kase.
- Conditions
- Low Back Pain, Pregnancy, Midwifery, Birth Self-efficacy
- Trial name
- kinesio tape (NCT07459231)
- Testing
- Kinesio Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ege University
Postpartum Hemorrhage
Administration Of Calcium Gluconate for The Reduction of Blood Loss During Vaginal Delivery
Postpartum hemorrhage is one of the leading causes of maternal morbidity following childbirth. Even when excessive bleeding is not clinically recognized, some women experience a significant decrease in hemoglobin levels after…
- Trial name
- NCT07714902
- Testing
- calcium gluconate
- Where
- Israel
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Contraception
The Direct Access Study: Access to Hormonal Birth Control Through Community Pharmacies
Hormonal birth control methods include birth control pills, patches, and vaginal rings; they are normally available only with a doctor's prescription.
- Trial name
- NCT00065871
- Testing
- Contraceptive Screening by Pharmacist, Contraceptive Prescribing by Pharmacist
- Where
- 5 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Preterm Birth
Prolonged Progesterone to Prevent Preterm Birth From IVF - ET
To investigate the incidence of preterm birth in IVF fresh embryo transplantation cycle patients after prolonged vaginal progesterone treatment
- Trial name
- NCT05787509
- Testing
- Progesterone Sustained-release vaginal gel
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University