Clinical trials: Validation Studies
Validation Studies, Magnetic Resonance Spectroscopy
Magnetic Resonance & Optical Spectroscopy Validation
The purpose of this study is to develop and refine techniques for using magnetic resonance and optical spectroscopy to investigate how your body uses energy.
- Trial name
- NCT01827527
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Psychological Well Being
Digital Self-Assessment of Well-Being: Validation of the Libellules Tool Against Gold-Standard Psychological Scales
The Libellules (WB6Dim) study aims to validate a digital self-assessment tool for measuring individual well-being across six dimensions: sleep and recovery, emotional climate, self-esteem, perceived autonomy, energy reservoir…
- Trial name
- NCT07301879
- Where
- France
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Clover Link
Healthy, Hypertension
A Validation Study of Selfie Technology for Assessment of Vital Signs
The aim of this study is to compare accuracy of DocMe, a video technology developed by DocMe Health Technologies, with previously validated medical devices used for measurements of heart rate, heart rate variability, respiratory…
- Trial name
- NCT05117762
- Where
- United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- DocMe Technologies Ltd
Oxygen Deficiency
Validation of the O3 Regional Somatic Tissue Oxygenation Monitor
Testing the absolute accuracy of the Masimo O3 regional oximeter in reading somatic tissue oxygenation in healthy volunteers under controlled hypoxia.
- Trial name
- NCT04584788
- Testing
- Masimo O3 Regional Oximeter
- Where
- Netherlands
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Neoplasms, Cancer
Blood Cell RNA-Based Cancer Detection
Early diagnosis of cancer may provide patients with more treatment options and hopefully prolong survival. The purpose of this multi-center study is to collect peripheral blood from newly diagnosed cancer patients and healthy…
- Trial name
- eRBCDet (NCT05839834)
- Testing
- Blood test
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Chronic Obstructive Pulmonary Disease Severe
Efficacy of an Advanced Auto-titrating NIV in COPD
Patients with chronic obstructive pulmonary disease (COPD) can eventually progress to respiratory failure, where they cannot adequately exchange oxygen and carbon dioxide, leading to worsening breathlessness, frequent…
- Trial name
- NCT04848012
- Testing
- Auto-titrating non-invasive ventilation
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Endometriosis
Turkish Validation Study of Endometriosis Health Profile -30 (EHP-30) Test
For the Turkish validation Study of the Endometriosis Health Profile test (EHP-30) consisting of 30 questions, this 30-question test will be applied to 228 patients after 2 different translations to be applied after the…
- Trial name
- NCT04862364
- Testing
- Endo Patients with Endometriosis Health Profile -30 (EHP-30) Test
- Where
- Turkey (Türkiye)
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Male Infertility
A Novel Sperm Selection Method Provides Advantages Over Conventional Approaches
The goal of this clinical trial is to know if a novel sperm selection device (CA0) has a similar performance than the standard selection method in teratozoospermic and azoospermic men.
- Trial name
- NCT06545318
- Testing
- Density Gradient Centrifugation, CA0 chamber
- Where
- Mexico
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Center of Innovation Technology & Reproductive Medicine
Cancer
Pan-canceR Early DetectIon projeCT (PREDICT)
PREDICT is a prospective, multicenter study for the early detection of pan-cancer through cell-free DNA (cfDNA) methylation-based model, in which approximately 14,000 participants will be enrolled.
- Trial name
- NCT04817306
- Testing
- Multi-cancer early detection test
- Where
- 3 sites in China
- Volunteers
- 14,026 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Hypoxia
Pulse Oximeter Validation Study for the Perin Health Patch
The goal of this clinical trial is to evaluate the accuracy of the Perin Health Patch, a chest-worn pulse oximeter, in healthy adult volunteers by comparing its measurements to arterial blood gas analysis during controlled…
- Trial name
- NCT07027150
- Testing
- Chest Worn Pulse Oximeter
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Perin Health Devices
HLH, Hemophagocytic Lymphohistiocytoses
Prospective Validation of the OHI Index
Hemophagocytic lymphohistiocytosis (HLH) associated with hematologic malignancies (HM-HLH) is a syndrome with an abysmal prognosis (10-30% 5 years overall survival).
- Conditions
- HLH, Hemophagocytic Lymphohistiocytoses, Hemophagocytic Syndrome, Hematologic Malignancy
- Trial name
- HLH (NCT05882175)
- Where
- 2 sites in Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Lymphedema
Validation of the MoistureMeterD in Local Edema by Histamine
In lymphedema there is increase in water content of the tissue. We studied a device (MoistureMeterD) which is suitable to detect water contact in the tissue.
- Trial name
- NCT01833156
- Testing
- MoistureMeterD
- Where
- Netherlands
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Nij Smellinghe Hosptial
Healthy
Cardiac Linear and Torsional Contractility Measurements With a New Technology: Multi Dimensional Kineticardiography
This study aims to validate the possibility to track cardiac contractility changes with a new technology called 'Heart Kinetic' (HK). HK measurements will be realized and compared echocardiography.
- Trial name
- MultiKinVal (NCT03107351)
- Testing
- Cardiac contractility assessments with Kino-cardiograph, Cardiac assessment repeatability with Kino-cardiograph
- Where
- Belgium
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Proof Of Concept Study
Measuring Hydrogen Peroxide in Exhaled Breath Condensate in HV
The purpose of this study is to evaluate the performance of an Exhaled Breath Condensate (EBC) device. EBC measurements can be used for the assessments of lung inflammation in asthma and chronic obstructive pulmonary disease…
- Trial name
- NCT05844553
- Testing
- Measurement of inhaled measuring hydrogen peroxide in exhaled breath
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Healthy
Pilot Study to Assess Feasibility, Reliability and Validity of the e-SSRS-IVR
The proposed study is designed to evaluate the clinical contents of the e-SSRS-IVR with respect to 1.the intent of the instrument (assess face and content validity), 2. system validation with respect to programming integrity, 3.
- Trial name
- e-SSRS-IVR (NCT00921466)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rogers Center for Research & Training, Inc.
Allergic Rhinitis, Rhinoconjunctivitis
Red Maple Trials Cat Allergen Natural Exposure Chamber Validation in Cat-allergic Subjects
To assess the reproducibility of the allergic response in the cat allergic subjects, measured as the change from baseline of the Total Nasal Symptom Score (TNSS) on the two challenge days.
- Conditions
- Allergic Rhinitis, Rhinoconjunctivitis, Exposure
- Trial name
- NEC (NCT03414801)
- Testing
- Allergen Exposure
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Red Maple Trials Inc.
Child Malnutrition, Wasting Syndrome
Laser Height Measuring Device Study in Vietnam
This study will evaluate whether a portable laser device can accurately measure the height and length of children younger than 5 years in Quang Nam, Vietnam.
- Conditions
- Child Malnutrition, Wasting Syndrome, Stunting
- Trial name
- NCT07906067
- Testing
- Laser Height/Length Measuring Device, ShorrBoard
- Where
- Vietnam
- Volunteers
- 571 people, healthy volunteers welcome
- Sponsor
- World Vision US
TURKISH VALIDITY AND RELIABILITY STUDY OF THE CORONAVIRUS IMPACT SCALE
The Coronavirus Impact Scale Validity and Reliability Study
This research; The Turkish validity and reliability study of the "Coronavirus Impact Scale" developed by Stoddard and Kaufman (2020) will be conducted in order to bring a new measurement tool to our country.
- Trial name
- NCT05017506
- Testing
- A survey will be made.
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ordu University
Suicide Prevention
Validation and Testing of a Suicide Prevention Program to Improve Mental Well-Being Among Adolescents in Gilgit Baltistan, Pakistan: A Pre/Post-Intervention Protocol
Background Globally, around 800,000 people die annually by committing suicide with a disproportionate burden of 77% of these deaths occurring in low- and middle income countries.
- Trial name
- Protocol (NCT06721364)
- Testing
- Suicide prevention treatment
- Where
- Pakistan
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Unrecognized Condition
Turkish Adaptation of Romantic Relationship Sabotage Scale Validity and Reliability Study
In this cross-sectional and relationship-seeking study, it was aimed to adapt the Romantic Relationship Sabotage Scale (T-RSS), developed by Racquel Peel, into Turkish, for the reasons why partners sabotage the relationship in…
- Trial name
- T-RSS (NCT05795998)
- Testing
- Adaptation of the Sabotage in Romantic Relationships Scale into Turkish and its validity and reliability analyzes
- Where
- Turkey (Türkiye)
- Volunteers
- 495 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey