Clinical trials: Validation Studies
Muscle Atrophy
Can Ultrasound be Used as a Measure of Muscle Quality? A Validation Study Comparing Ultrasound With MRI and MRS in Older and Younger Persons.
This study aims to see if ultrasound can be used as a reliable and valid method to measure fatty infiltration, muscle thickness and muscle architecture to provide a quick, cheap and mobile alternative measure of muscle quality to…
- Trial name
- NCT05729880
- Testing
- MRI, MRS, Ultrasound
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Pelvic Floor Dyssynergia
Reliability and Validation of 3-D Electromagnetic Tracking During Pelvic Floor Muscle (PFM) Activation - a Pilot Study
Now a days the ultrasound is seen as a valid and reliable measurement tool to test the Pelvic Floor Muscle (PFM) movement (Sherburn, Murphy, Carroll, Allen, \& Galea, 2005).
- Trial name
- NCT01590927
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Moser, Helene
Lymphedema
Validation of the MoistureMeterD in Local Edema by Histamine
In lymphedema there is increase in water content of the tissue. We studied a device (MoistureMeterD) which is suitable to detect water contact in the tissue.
- Trial name
- NCT01833156
- Testing
- MoistureMeterD
- Where
- Netherlands
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Nij Smellinghe Hosptial
Endometriosis (Diagnosis), Identification of Biomarkers in Serum
CellAdhesionMolecule EndometriosisRatio - CAMERA
Background: Endometriosis, which is characterized by the growth of endometrial stroma and glands outside of the uterine cavity, is estimated to occur in 6-10% of women of reproductive age.
- Trial name
- CAMERA (NCT04294017)
- Where
- Austria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Heinrich Husslein
Validation, Blood Pressure
Is Continuous Non-Invasive Monitoring Accurate When Used on the Lower Extremity: Finger Vs Toe?
The goal of this observational study is to assess the validity of a continuous non-invasive blood pressure monitoring device, Acumen IQ cuff (Edwards Lifesciences LLC, Irvine, CA), when used on the toe in healthy volunteers.
- Conditions
- Validation, Blood Pressure, Device
- Trial name
- NCT06805435
- Testing
- Continuous non-invasive blood pressure monitoring
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riverside University Health System Medical Center
Rotator Cuff, Syndrome, Frozen Shoulder
Validation of a Kinematic Functional Shoulder Score Including Only Essential Movements
A lot of shoulder function evaluation scores exist but none has been universally accepted as a gold standard. Recent studies have demonstrated the potential of computerized movement analysis with embedded sensors for objective…
- Conditions
- Rotator Cuff, Syndrome, Frozen Shoulder, Humerus, Fracture, Other Instability of Joint, Shoulder Region
- Trial name
- NCT01431417
- Where
- Switzerland
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Haute Ecole de Santé Vaud
Depressive Disorder, Major
Study to Evaluate the Performance Validity and Test-Retest Reliability of a Computer-Administered Cognitive Test Battery in Participants With Major Depressive Disorder (MDD)
The purpose of this study is to examine concurrent validity of 8 computerized tests intended for the assessment of cognitive function in participants with Major Depressive Disorder (MDD), relative to 8 corresponding and…
- Trial name
- NCT03014544
- Testing
- Computer- administered test battery, Examiner- administered test battery
- Where
- 20 sites in United States
- Volunteers
- 585 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Omphalitis
Omphalitis Community Based Algorithm Validation Study
The objective of this study is to develop and test a simple community-based diagnostic algorithm for omphalitis in sub-Saharan Africa.
- Trial name
- OCAVS (NCT01687621)
- Testing
- Diagnostic Algorithm for Community Based Worker for Omphalitis
- Where
- Zambia
- Volunteers
- 1,009 people, healthy volunteers welcome
- Sponsor
- Boston University
Healthy
A Study to Validate Treadmill Parameters
The purpose of this study is to evaluate the accuracy with which a microprocessor-controlled treadmill delivers controlled postural disturbances.
- Trial name
- NCT05333263
- Testing
- Treadmetrix
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Intubation, Intratracheal, Airway Management
A Novel Score for Procedural Difficulty During Videolaryngoscopic Intubation
Videolaryngoscopy generally improves the glottic view compared with direct laryngoscopy, yet a good view does not always translate into easy delivery of the tracheal tube.
- Conditions
- Intubation, Intratracheal, Airway Management, Videolaryngoscopy
- Trial name
- ZVL-DT (NCT07873138)
- Testing
- Videolaryngoscopic tracheal intubation
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Nagihan Emiroglu
Sleep Apnea
Validation of Software for Assessment of Sleep Apnea From Data Acquired by a Wearable Smartwatch
This clinical validation study aims to evaluate the utility of Fitbit's Sleep Apnea Alert software for minimally invasive monitoring of sleep apnea events to alert users of their risk of sleep apnea.
- Trial name
- NCT03775291
- Testing
- Simultaneous assessment of sleep apnea by polysomnogram and wearable device
- Where
- 6 sites in United States, Ireland
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- Fitbit LLC
Mild Cognitive Impairment (MCI), Healthy Aging
cMIND AI Web Tool Usability Study (Hong Kong)
This study is testing a new web-based tool that uses artificial intelligence (AI) to help older adults in Hong Kong check how healthy their Cantonese-style meals are for brain health.
- Conditions
- Mild Cognitive Impairment (MCI), Healthy Aging, Nutrition
- Trial name
- NCT07735013
- Testing
- Web-Based AI Dietary Assessment System
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hong Kong Metropolitan University
NAFLD, NASH - Nonalcoholic Steatohepatitis
Development and Validation of a Multi-target, Blood-based NAFLD Diagnosis Test
Multi-omics approach was used to identify patterns of serological biomarkers to diagnose NAFLD. The purpose of this study is to develop and validate a blood-based assay to diagnose NAFLD by collecting blood sample from healthy…
- Trial name
- NCT05108415
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- HBI Solutions Inc.
Attitude of Health Personnel
Manual Therapy Behavior Scale in Physiotherapists
The aim of this study is to develop a scale to assess the manual therapy application behaviors of physiotherapists in Türkiye, based on the Theory of Planned Behavior (Ajzen, 1991).
- Trial name
- NCT07296380
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Uşak University
Obstructive Sleep Apnea
Evaluation of Post-surgical Improvement in OSA Patients After Imaging of Upper Airway Using CBCT and DISE vs DISE Only
CBCT is considered an innovative imaging modality that can view the upper respiratory airway anatomy in a 3D manner. Recent studies tried to evaluate the accuracy of CBCT in analyzing the upper respiratory airway and its related…
- Trial name
- NCT04727346
- Testing
- CBCT, DISE
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pancreatic Cancer Stage I, Pancreatic Cancer Stage II
Clinical Validation of Immunovia Next-Generation Blood Biomarker Test to Detect Early-Stage Pancreatic Cancer
This is a case-control study to clinically validate the performance of a protein biomarker test to differentiate Stage I and Stage II pancreatic ductal adenocarcinoma (PDAC) patient samples from samples acquired from control…
- Conditions
- Pancreatic Cancer Stage I, Pancreatic Cancer Stage II, Cancer Diagnosis, PDAC - Pancreatic Ductal Adenocarcinoma
- Trial name
- CLARITI (NCT06947382)
- Where
- 15 sites in United States, Canada and 2 more
- Volunteers
- 1,066 people, healthy volunteers welcome
- Sponsor
- Immunovia, Inc.
Cardiovascular Risk Factor, Cardiovascular Diseases
VOPITB a New Devices to Determine Peripheral Arterial Stiffness: Validation Study
Our group has developed a device called "Velocidad Onda de Pulso Indice Tobillo Brazo (VOPITB)" . In this device the oscillometric method is used for easily and accurately measure the pulse wave velocity PWV in the arms and legs…
- Conditions
- Cardiovascular Risk Factor, Cardiovascular Diseases, Atherosclerosis of Artery
- Trial name
- NCT04303546
- Testing
- arterial stiffness measurements
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Gastroparesis
ABCA2 GIRMS Analytical Validation Clinical Performance Study
The purpose of this study is to collect human breath samples for use in a validation study intended to demonstrate equivalent clinical performance measures of new ABCA2 GIRMS (Automated Breath Carbon Analyzer-2 Gas Isotope Ratio…
- Trial name
- NCT04607304
- Testing
- ABCA2 GIRMS
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Cairn Diagnostics
Sleep, Sleep Disorder
Validation Study of Sleep Tracking Devices
In this study, a two-part recursive convolutional neural networks model was developed, extracting features for each epoch window independently from before and after sleep onset (epoch encoder), and then trained in the context of…
- Trial name
- NCT06357039
- Testing
- Sleep tracking device
- Where
- Turkey (Türkiye)
- Volunteers
- 305 people, healthy volunteers welcome
- Sponsor
- PNAPS Health Informatics and Space Technologies Inc.
Myopia, Hyperopia
Comparing Low-cost Handheld Autorefractors - a Practical Approach to Measuring Refraction in Low Resource Settings
Study compares four portable vision measurement and eye-imaging technologies in terms of accuracy and time and ease of use with older adult (ages 40-100) participants in a developing-country setting (India).
- Trial name
- NCT03456245
- Testing
- Vision device validation
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)