Clinical trials: Variability
Diabetes Mellitus
Potential Correlation Between Heart Rate Variability With Cardiovascular Risk at Different Stages of Metabolic Syndrome
The study aims to assess the beat-to-beat Heart rate variability (HRV) in different stages of metabolic diseases, including pre-diabetic and diabetic patients, compared to non-diabetic individuals.
- Trial name
- NCT06305195
- Testing
- heart rate variability test
- Where
- Egypt
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Obesity, Severe Obesity
Energy Expenditure From ECAL Indirect Calorimeter in a Multicomponent Weight Management Service
Whether greater weight loss is as a result of a smaller reduction in energy expenditure with caloric restriction is not known. Resting energy expenditure and 24-hour energy expenditure vary substantially between individuals.
- Conditions
- Obesity, Severe Obesity, Sleep Apnoea
- Trial name
- ECAL (NCT03638895)
- Testing
- ECAL Indirect Calorimeter, Diet, exercise & behaviour modification therapy
- Where
- United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Adults With Variability in Their Mood
Restorative Neurophysiology: Backing up and Restoring the Brain (BandR)
Study to examine the extent to which neurophysiological states recorded for a specific person on one day can be induced on a subsequent day
- Trial name
- BandR (NCT07252011)
- Testing
- Transcranial alternating current stimulation (tACS), Neuro/biofeedback, Recall
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Hypertension, Vitamin D Deficiency
The Impact of Vitamin D Supplementation in Hypertensive Vitamin D Deficient Patients.
This study will assess the impact of Vitamin D supplementation on hypertensive patients with Vitamin D deficiency, it will also investigate the relationship between serum Vitamin D, irisin levels, blood pressure, and heart rate…
- Trial name
- NCT06645041
- Testing
- Vitamin D (Cholecalciferol )
- Where
- 3 sites in Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sulaimani
Diabetes, Obesity
Glycemic Index - Variability Among Individuals
The purpose of this study is to determine the variability in glycemic index determinations for individual foods and food combinations.
- Conditions
- Diabetes, Obesity, Metabolic Syndrome, Cardiovascular Disease
- Trial name
- NCT01023646
- Testing
- Carbohydrate + Protein, Carbohydrate + Fat, Fiber
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Tufts University
Cognitive Fatigue, Mental Fatigue
Effects of Natural Sounds on Attention Restoration in Virtual Reality
This study aims to examine whether listening to natural sounds in a noisy virtual reality environment compared to no natural sounds influences physiological markers.
- Conditions
- Cognitive Fatigue, Mental Fatigue, Behavioral Performance, Heart Rate Variability
- Trial name
- VEARS (NCT05679869)
- Testing
- Masking Sound, No masking sound
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Hypertension, Autonomic Dysfunction
Autonomic Regulation of Blood Pressure and Heart Rate During Orthostasis and Exercise in Healthy and Hypertensive Individuals
The goal of this observational study is to assess arterial stiffness and autonomic regulation of blood pressure and heart rate in healthy adults and people with arterial hypertension during orthostatic stress and graded physical…
- Conditions
- Hypertension, Autonomic Dysfunction, Orthostatic Hypotension
- Trial name
- NCT07482462
- Where
- Slovenia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Athletic Performance, Cognitive Fatigue
TCP-600 Supplementation and Performance Response in Professional Football Players
This study will examine whether a 28-day supplementation protocol containing taurine, caffeine, and phosphatidylserine can help professional male football players maintain physical performance, cognitive function…
- Conditions
- Athletic Performance, Cognitive Fatigue, Exercise Recovery, Football-Specific Performance
- Trial name
- TCP600-RESP (NCT07710547)
- Testing
- Taurine, Caffeine, Phosphatidylserine
- Where
- 3 sites in Poland
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Vizja University in Warsaw
Autonomic Nervous System Activity, Cardiovascular
Investigation of Autonomic Stress Response Patterns in College Students With Varying Physical Activity Levels
This study aims to investigate the differences in cardiovascular stress response patterns among individuals with various physical activity levels (sedentary controls and different types of athletes).
- Conditions
- Autonomic Nervous System Activity, Cardiovascular, Physical Activity Level
- Trial name
- ANS Stress/PA (NCT07360821)
- Testing
- Cardiopulmonary Exercise Testing
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Stress
AI and Mindfulness Meditation for Stress Reduction in Medical Students
The goal of this clinical trial is to learn if two stress-reduction methods can lower stress in medical students. The study compares a wearable device and a mindfulness program.
- Trial name
- NCT07591935
- Testing
- Mindfulness-Based Stress Reduction Course, Apollo Neuro Wearable
- Where
- Anguilla
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Saint James School of Medicine
Anesthesia, General, Fluid Therapy
Management of Intraoperative Fluids in Ambulatory Surgery
This is a single-center prospective randomized control trial (RCT) to determine whether the continuous monitoring of the plethysmographic variability index (PVI) during low-risk surgeries, can be used to optimize the…
- Conditions
- Anesthesia, General, Fluid Therapy, Ambulatory Surgical Procedures
- Trial name
- MIFAS (NCT03193320)
- Testing
- Fluid therapy protocol
- Where
- Venezuela
- Volunteers
- 243 people, healthy volunteers welcome
- Sponsor
- Policlinica Metropolitana
Head and Neck Cancers
SOMESThesia and ALIMentation
Cancer patients are at high risk for undernutrition. A study with head and neck cancer patients showed that 50% suffered from undernutrition (Prevost et al., 2014).
- Trial name
- SOMEST'ALIM (NCT05272917)
- Testing
- Sensorial tests, food preferences questionnaires
- Where
- 2 sites in France
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Copd, Aging
Evaluation of Cardiac Variability After a Vitamine D Protocol and Whole Body Vibration
Evaluation of heart rate variability in time and frequency domains, in Chronic Obstructive Pulmonary Disease (COPD) after 03 months of vitamine D supplementation and whole body vibration (WBV) training
- Trial name
- NCT03679325
- Testing
- vitamine D, whole body vibration (WBV)
- Where
- Brazil
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Maíra F Pessoa
Smartphone Users, Smartphone Addiction, Anxiety, and Skin Conductance
The Relationship Among Electroencephalography,Skin Conductance Response,Heart Rate Variability and Mental Health Among Smartphone Users After Receiving Texting or Calling
The number of smartphone users in Taiwan continues to increase exponentially. Smartphone addiction tends to not only disrupt the ability of social communication but cause physical and psychological problems as well.
- Trial name
- NCT04133597
- Testing
- social media stimuli (Line app)
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Sleep
Stable Sleep Pattern Before Sleep Loss
Sleep is now recognized as important for disease prevention. Too little or too much sleep contributes to cardiovascular disease. Leading health organizations recommend adults sleep 7-9 hours per night for optimal health.
- Trial name
- NCT06201390
- Testing
- Sleep consistency
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Myopia
Assessment of Measurement Variability Across Automated Biometry Devices
This is a non-interventional prospective, comparative study of white-to-white, corneal thickness, and anterior chamber depth measurements as taken on the Orbscan II compared to the IOL Master 700 (Zeiss), IOL Master 500 (Zeiss)…
- Trial name
- NCT06045325
- Testing
- Orbscan II, IOL Master 700, IOL Master 500
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Berkeley Eye Center
Insomnia, Anxiety
Evaluation of Physiological Effects Induced by Low Level Light Irradiation on the Acupoints of the Hand
The goal of this clinical trial is to determine if low-level laser therapy (LLLT) and LED-based low-level light therapy (LLLT) are effective in inducing relaxation and improving sleep quality and anxiety levels in individuals…
- Conditions
- Insomnia, Anxiety, Acupuncture, Low-level Laser Therapy
- Trial name
- Acupuncture (NCT07190417)
- Testing
- LEDs and laser light
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Autonomic Nervous System Imbalance, Hypovolemia
Autonomic Challenges From Mild Hypovolemia and Mechanical Ventilation
Heart Rate Variability (HRV) analysis has been studied in the critically ill patients although it is affected by several uncontrolled variables in the clinical conditions.
- Conditions
- Autonomic Nervous System Imbalance, Hypovolemia, Positive-Pressure Respiration
- Trial name
- NCT03244891
- Testing
- Increase of central volume, Ventilation mode
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- ASST Fatebenefratelli Sacco
Burnout, Burnout Syndrome
Continuous Heart Rate Variability Monitoring in Doctors; Understanding Patterns of Stress and Recovery and Their Relationship With Self-reported Resilience, Burnout and Wellbeing.
Burnout is an increasing concern in the medical professions. This study aims to utilise established, validated self-report measures combined with continuous heart rate variability measurements to better understand the stress and…
- Conditions
- Burnout, Burnout Syndrome, Occupational Stress, Stress
- Trial name
- HEART-ED (NCT06721312)
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Autonomic Neuropathy
A Comparison Between Pupillometry, Heart Rate Variability and Metaiodobenzylguanidine Scintigraphy for the Diagnosis of Early Diabetic Autonomic Neuropathy in Type 1 Diabetes
This study will examine if one of the following methods: pupillometry, spectral analysis of heart rate variability and metaiodobenzylguanidine scintigraphy, is more capable to detect early diabetic autonomic neuropathy in…
- Trial name
- NCT01822431
- Testing
- metaiodobenzylguanidine scintigraphy
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- AHEPA University Hospital