Clinical trials: Variability
Healthy Volunteers
Energy Drink Habituation Effects on Young Adults
The consumption of energy drinks has significantly increased in recent years but their adverse effects are not yet efficiently known.
- Trial name
- NCT04223167
- Testing
- Red Bull Energy Drink, Water
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Experimental Pain
Gender, Pain, and Placebo Analgesia
The response to standard pain stimuli in males and females is investigated, together with the effect of informing participants about the effect of a painkiller. Physiological response to pain is recorded.
- Trial name
- NCT00314392
- Testing
- Information (behavior)
- Where
- Norway
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Cognitive Fatigue, Mental Fatigue
Effects of Cognitive Fatigue on Heart Rate Variability and Skin Conductance
This study aims to examine the effects of cognitive fatigue on heart rate variability and skin conductance and develop a machine learning model.
- Conditions
- Cognitive Fatigue, Mental Fatigue, Behavioral Performance, Heart Rate Variability
- Trial name
- FRESH (NCT05011318)
- Testing
- Baseline, Fatigue Manipulation
- Where
- Singapore
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Grief, Cardiovascular Health
Cardiovascular Effects of Grieving
Self-affirmation (SA) theory proposes that people are motivated to maintain a positive self-image of being worthy, stable, and capable.
- Conditions
- Grief, Cardiovascular Health, Emotion
- Trial name
- SAGE (NCT07356635)
- Testing
- Value-affirmation
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Functional Gastrointestinal Disorders (FGIDs)
A Heart Rate Variability (HRV) Biofeedback Training in Functional Gastrointestinal Disorders (FGID)
Functional Gastrointestinal Disorders (FGIDs) are conditions characterized by chronic gastrointestinal symptoms without evidence of pathology. These disorders are believed to result from alterations in gut-brain communication.
- Trial name
- BF_FDGI (NCT06687057)
- Testing
- HRV Biofeedback Training
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Healthy
Analysis of Atropine and Propranolol Induced Changes
The purpose of this study is to learn the effects of genetic make up on response to the drugs atropine and propranolol, to examine how changes in heart rate and blood pressure can be measured, and to test a new statistical…
- Trial name
- NCT00251602
- Testing
- Atropine, Propranolol, Normal Saline
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Infertility, Heart Rate Variability
Trajectory of Psychological Distress Among Infertility Women
Background: Infertility is a serious reproductive health issue and affects 48.5 million couples worldwide. Women undergoing fertility treatment often experienced psychological distress but also social stigma that is close linked…
- Conditions
- Infertility, Heart Rate Variability, Biofeedback
- Trial name
- NCT04829877
- Testing
- Web-based mind-body intervention with HRVB, Web-based mind-body intervention
- Where
- Taiwan
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Breast Cancer-Related Lymphedema, Autonomic Dysfunction
Evaluation of Sympathetic Skin Response and Its Relationship With Clinical Response to Complex Decongestive Therapy in Patients With Postmastectomy Lymphedema
This prospective observational single-center study aimed to evaluate sympathetic skin response (SSR) in patients with postmastectomy upper extremity lymphedema and to investigate the relationship between SSR parameters and…
- Conditions
- Breast Cancer-Related Lymphedema, Autonomic Dysfunction, Postmastectomy Lymphedema
- Trial name
- BCRL-SSR (NCT07585253)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Concussion
Vascular Assessment of Regulation Index Arrays Registry
The objective of this patient registry is to collect and analyze physiological data associated with baseline and brain injury identified in standard clinical practice (Normal Values, Recovery Curves, Correlation between Symptoms…
- Trial name
- VARIA (NCT02435082)
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- NeuroChaos Solutions, Inc.
Acute Psychophysiological Responses to Heart Rate Variability Biofeedback
Effects of Brief Heart Rate Variability Biofeedback on Physiological and Emotional Responses
This completed randomized laboratory study investigated the immediate effects of a single 10-minute session of heart rate variability biofeedback (HRV-B) on cardiac activity, forehead physiological signals, and emotional…
- Trial name
- NCT07911215
- Testing
- Psychoeducational Video Viewing, Heart Rate Variability Biofeedback
- Where
- Israel
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Premature Ejaculation
Vagus Nerve Stimulation in Premature Ejaculation
Introduction: Premature ejaculation (PE), one of the most common sexual dysfunctions in men, negatively affects sexual function and quality of life.
- Trial name
- NCT07300774
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Athletic Performance, Sports Performance
Effects of Afternoon Napping, Caffeine, and Standardised Active Recovery on Evening Athletic Performance
This study evaluated whether afternoon napping, caffeine ingestion, and a standardised active recovery and nutritional protocol could influence evening physical and cognitive performance in healthy university athletes.
- Conditions
- Athletic Performance, Sports Performance, Exercise Performance, Circadian Rhythm
- Trial name
- NAP-CAF-REC (NCT07652424)
- Testing
- Afternoon Nap, Caffeine, Standardised Active Recovery and Nutritional Protocol
- Where
- Tunisia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Higher Institute of Sport and Physical Education of Sfax
Postoperative Pain
The Effect of Local Anaesthetic Volume on Nerve Block Duration and Nerve Block Duration Variability
The aim is to investigate the effect of perineural administration of a series of different volumes of local anaesthesia (ropivacaine 0.2%) on nerve block duration and the variability of the duration in the common peroneal nerve…
- Trial name
- NCT02829697
- Testing
- Ropivacaine
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Glucocorticoids Toxicity, Glucose Intolerance
Pharmacogenomics of the Variability in the In Vivo Response to Glucocorticoids
This study evaluates the effect of acute administration of oral prednisone in white blood cells counts and glucose tolerance and the relationship of these measures with changes in gene expression in healthy volunteers.
- Trial name
- NCT03023891
- Testing
- Prednisone
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Burnout, Professional
Impact of Heart Rate Variability Modulation on Stress Management Among Physicians
The purpose of this research is to examine a wearable device called Apollo that emits gentle vibrations found to benefit mood, energy, and focus. We want to understand how it affects burnout in physicians.
- Trial name
- NCT05731856
- Testing
- Apollo Wearable
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Michelle Thompson
Non Dependant 60 to 75 Year-old Men and Women
Multidimensional Phenotyping Towards Personalized Preventive Nutritional Support for Elderly People
There is high inter-individual variability in the response to feeding, which is determined by multiple interacting factors such as age, sex, genotype, gut microbiota, eating behaviors, physical activity or even socio-demographic…
- Trial name
- MetabotypAGE (NCT06163794)
- Testing
- Nutritional postprandial test
- Where
- 3 sites in France
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Heart Rate Variability, Burnout
Helping Overcome Pressure and Exhaustion: Empowerment Classes for Southeast Asian Migrant Care Workers
As Taiwan's population ages, Southeast Asian migrant care workers are widely employed to fill the care labor gap. These workers often face symptoms of burnout and emotional stress due to long working hours and high-pressure…
- Conditions
- Heart Rate Variability, Burnout, Depression
- Trial name
- HOPE (NCT06532305)
- Testing
- HOPE empowerment classes
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Healthy Adult Participants
The Effect of A Slow-Paced Breathing Intervention on Heart Rate Variability, Stress, and Dysfunctional Breathing Patterns in Healthy Young Adults
The primary aim of this study is to evaluate the effects of a controlled breathing exercises-on autonomic nervous system functions (HRV) and perceived stress levels in healthy young adults with dysfunctional breathing patterns.
- Trial name
- SPB-HRV-RCT (NCT07874750)
- Testing
- slow-paced breathing
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Exercise
Smartphone-Based Use of Phonocardiography Technique for Estimating Heart Rate and Heart Rate Variability: Performance Study
This study aims to investigate the use of heart sound recordings, or phonocardiograms, recorded with smartphones' built-in microphones and accessory microphones to estimate heart rate (HR) and heart rate variability (HRV).
- Trial name
- NCT06848179
- Testing
- Computer algorithms, Exercise
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Preoperative Vegetative Stress
Correlation Between State-Trait-Anxiety-Inventory and Heart Rate Variability
The purpose of the study is to investigate whether there is a correlation between the vegetative stress evaluated by the State-Trait-Anxiety-Inventory (STAI-Test) and the measurement of heart rate variability (HRV).
- Trial name
- NCT06093750
- Where
- Austria
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ludwig Boltzmann Institute for Traumatology - The research center in cooperation with AUVA