Clinical trials: Variability
Sleep Disorder
Effects of an Osteopathic Treatment Protocol on Sleep Quality
SIngle-centre interventional single-blinded randomized controlled trial, with random assignment of the subjects in two groups (intervention and control, 1: 1 ratio) and to be carried out with volunteers that present alterations…
- Trial name
- NCT04955392
- Testing
- Osteopathic treatment protocol
- Where
- Spain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ramón Mateos Alpuente
Somatoform Disorders, Irritable Bowel Syndrome
Neurovegetative Decoupling in Somatoform Disorders : Biofeedback Interest
Evaluation of the physiological and clinical effects of the biofeedback training with patients suffering from somatoform disorders, depending on their neurovegetative profile related to a visceral-brain decoupling.
- Conditions
- Somatoform Disorders, Irritable Bowel Syndrome, Psychogenic Non-Epileptic Seizure
- Trial name
- BIOFEESOMATO (NCT04807933)
- Testing
- Heart rate variability Biofeedback [HRV-BFB]
- Where
- France
- Volunteers
- 46 people
- Sponsor
- University Hospital, Grenoble
Diabetes Complications
Pyridostigmine and Its Effects on Autonomic Modulation in Diabetic Patients
The purpose of the study is to determine if pyridostigmine bromide improves heart rate variability of type 2 diabetes mellitus subjects with cardiovascular autonomic neuropathy.
- Trial name
- NCT00953914
- Testing
- Pyridostigmine
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Blood Pressure Immeasurable
Development of a Prediction Model for Intraoperative Blood Pressure Variability
Objective: The aim of this study was to use machine learning to predict and interpret intraoperative high blood pressure variability（IHBPV）. Design: Retrospective cohort study. Setting: Beijing Tsinghua Chang Gung Hospital .
- Trial name
- NCT05698433
- Testing
- No intervention
- Where
- China
- Volunteers
- 47,520 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Hearing Loss, Age-Related, Speech Intelligibility
Benefits of Choir for Older Adults With Unaddressed Hearing Loss (WP2)
Unaddressed age-related hearing loss is highly prevalent among older adults, typified by negative consequences for speech-in-noise perception and psychosocial wellbeing.
- Conditions
- Hearing Loss, Age-Related, Speech Intelligibility, Psychosocial Functioning
- Trial name
- NCT06580847
- Testing
- Group Singing, Audiobook Club
- Where
- 7 sites in United States, Australia and 3 more
- Volunteers
- 210 people
- Sponsor
- Toronto Metropolitan University
Hemodialysis Patients
Reducing Dialysate Sodium Effect on Blood Pressure Variability in Hemodialysis Patients
In this study the investigators aim to test the effect of lowering dialysate sodium concentration on visit-to-visit blood pressure variability in hemodialysis patients who have achieved their dry weight.
- Trial name
- NCT05169125
- Testing
- standard hemodialysis, lower dialysate sodium dialysis
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Atopic Dermatitis
Atopic Dermatitis Research Network (ADRN) Influenza Vaccine Pilot
A new flu vaccine which is injected into the skin instead of into the muscle has recently been approved by the Food and Drug Administration for vaccination of the general population including patients with atopic dermatitis (AD).
- Trial name
- NCT01518478
- Testing
- Fluzone® Intradermal (Sanofi Pasteur Inc.)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Grief, Cardiovascular Health
Cardiovascular Effects of Grieving
Self-affirmation (SA) theory proposes that people are motivated to maintain a positive self-image of being worthy, stable, and capable.
- Conditions
- Grief, Cardiovascular Health, Emotion
- Trial name
- SAGE (NCT07356635)
- Testing
- Value-affirmation
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Heart Diseases, Hyperglycemia
Remifentanil and Glycemic Response in Cardiac Surgery
This study evaluates the effect of using remifentanil during cardiopulmonary bypass surgery to supress the hyperglycemic response in perioperative period.
- Trial name
- NCT02349152
- Testing
- Remifentanil, Fentanyl
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Kathirvel Subramaniam
Coronary Artery Disease
Antiplatelet Response, Interval Variability & Events in Percutaneous Coronary Intervention (ARIVE-PCI) Registry
Subjects in this study have recently had or are scheduled for a percutaneous coronary intervention (PCI) as part of their normal, routine medical care. This procedure should restore the blood flow in the vessels of the heart.
- Trial name
- ARIVE-PCI (NCT01278043)
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- University of Chicago
Cardiovascular Diseases, Coronary Disease
Heart Rate Variability and Sudden Cardiac Death
To evaluate the ability of heart rate variability to identify myocardial infarction patients at high risk of dying, particularly from sudden cardiac death.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Infarction
- Trial name
- NCT00005235
- Where
- United States
- Volunteers
- 715 people
- Sponsor
- Columbia University
Asthma
Heart Rate Variability Biofeedback: It's Role in Asthma Therapeutics
The goal of this research study to see whether biofeedback therapy helps treat asthma, and if so, how it works. Biofeedback is a treatment method that can teach how to bodily control.
- Trial name
- BioAce (NCT02766374)
- Testing
- Heart rate variability biofeedback
- Where
- 2 sites in United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Fred Wamboldt, MD
Diabetes, Obesity
Glycemic Index - Variability Among Individuals
The purpose of this study is to determine the variability in glycemic index determinations for individual foods and food combinations.
- Conditions
- Diabetes, Obesity, Metabolic Syndrome, Cardiovascular Disease
- Trial name
- NCT01023646
- Testing
- Carbohydrate + Protein, Carbohydrate + Fat, Fiber
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Tufts University
Hypothyroidism
Walking for Hypothyroidism Trial (WHT)
Women with hypothyroidism often report persistent fatigue, weight gain, autonomic dysregulation, and stress despite stable levothyroxine therapy.
- Trial name
- WHT (NCT07205042)
- Testing
- Supervised Walking Program
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- University of Karachi
Poor Sleep Quality
Effects of a Programmed Reflexology Therapy on Sleep Quality, Insomnia, Fatigue, and Heart Rate Variability Among Individuals With Poor Sleep Quality
The goal of this clinical trial is to evaluate whether a structured reflexology therapy can improve sleep, reduce insomnia severity, and alleviate fatigue in adults with poor sleep quality, and to understand how it affects…
- Trial name
- NCT07402460
- Testing
- manual reflexology treatment, Feet massage using an electric massager (FEM)
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Heart Rate Variability
Effects of Arm Crank Versus Treadmill Exercises on Heart Rate Variability in Adult Subjects.
Cardiovascular response to exercise affects the capacity of all body organs depending upon intensity, duration and mode of exercises.
- Trial name
- NCT03068182
- Testing
- Arm crank, Treadmill, Exercise
- Where
- Saudi Arabia
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Type 1 Diabetes, Diabetes Complications
Individualised Postprandial Glucose Responses in Type 1 Diabetes
Type 1 diabetes (T1D) is a lifelong disease which stops the body from producing insulin - an important hormone that controls blood sugar (glucose) levels.
- Conditions
- Type 1 Diabetes, Diabetes Complications, Postprandial Hyperglycemia
- Trial name
- NCT05231642
- Testing
- Nutritional Interventional
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- University of Sunderland
Treatment Resistant Schizophrenia, Clozapine Adverse Reaction
Effect of Atenolol Versus Ivabradine on HRV in TRS Patients on Clozapine With Tachycardia: A Randomised Control Trial.
Clozapine is the only drug approved for Treatment Resistant Schizophrenia. However, it has been associated with many adverse drug reactions including agranulocytosis, myocarditis, sialorrhea, constipation, orthostasis…
- Conditions
- Treatment Resistant Schizophrenia, Clozapine Adverse Reaction, Heart Rate Variability, Tachycardia
- Trial name
- NCT06505668
- Testing
- Atenolol 25 mg, Ivabradine 10mg
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Muscle Relaxation
Interindividual Variability in Duration of Action of Rocuronium in Pediatric Patients
Muscle relaxants represent an important part of general anesthesia in adult and pediatric patients. Their role is to facilitate intubation and enable some surgical interventions.
- Trial name
- DurAct (NCT05529420)
- Testing
- measurement of the depth of neuromuscular blockade
- Where
- Czechia
- Volunteers
- 107 people
- Sponsor
- Brno University Hospital
Atrial Fibrillation, Type 2 Diabetes
The Effect of High-Intensity Interval Training on Glucose Variability and Atrial Fibrillation Symptoms
The incidence of atrial fibrillation (AF), the most common heart rhythm disorder, is increasing. The symptoms of AF include: unpleasant heartbeats; difficulty breathing; tiredness; dizziness; and, reduced exercise capacity.
- Trial name
- Glucose-AF (NCT04190212)
- Testing
- High-intensity interval training + standard care
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Ottawa Heart Institute Research Corporation
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