Clinical trials: Vascular Surgical Procedures
Occlusions Vein, Chronic Venous Insufficiency
Cyanoacrylate Closure Versus Surgical Stripping for Incompetent Saphenous Veins
The purpose of this study is to evaluate the non-inferior, clinical outcomes after cyanoacrylate closure comparing the surgical stripping for incompetent saphenous veins.
- Trial name
- CASS (NCT03835559)
- Testing
- Cyanoacrylate closure, Surgical stripping
- Where
- 2 sites in South Korea
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Kyung Hee University Hospital at Gangdong
Intracerebral Hemorrhage
Clinical Outcomes Following Parafascicular Surgical Evacuation of Intracerebral Hemorrhage: A Pilot Study
This study is determining the clinical outcomes, based on neurological testing, for the parafascicular minimally invasive clot evacuation technique. We will collect data from the time of surgery up until 90 days post procedure.
- Trial name
- MISPACE (NCT01971359)
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- OSF Healthcare System
Cesarean Section, Pregnancy Related
Brain Oxygenation in Newborns Due to Neuroaksial Methods
Epidural and spinal anesthesia techniques are frequently used all over the world in elective cesarean section operations. To evaluate the effects of epidural and spinal anesthesia techniques applied in cesarean section surgery on…
- Conditions
- Cesarean Section, Pregnancy Related, Cerebral Hypoxia, Anesthesia, Regional
- Trial name
- oxygenation (NCT06316596)
- Testing
- Spinal Anesthesia, Epidural Anesthesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Acute Myocardial Infarction
Molecular and Morphologic Characterization of Circulating Endothelial Cells
The primary hypothesis of this study is that circulating endothelial cells (CECs) harbor key genetic and structural characteristics predisposing individuals to acute atherosclerotic plaque rupture and heart attack.
- Trial name
- CEC (NCT01005485)
- Where
- United States
- Volunteers
- 664 people, healthy volunteers welcome
- Sponsor
- Scripps Translational Science Institute
Complication of Surgical or Medical Care
Incidence, Predictors and Validation of Risk Scores to Predict Myocardial Infarction After Noncardiac Vascular Surgery
Evaluate the incidence and predictors of post-operative mortality after noncardiac Vascular Surgery and compare the performance of existing risk scores.
- Trial name
- NCT04051749
- Testing
- Noncardiac Vascular Surgery
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar De São João, E.P.E.
Obesity, Diabetes
Effects of Prevena Therapy on Obese and or Diabetic Patients With Surgical Groin Sites
The purpose of the study is to determine the effects of Prevena therapy on decreasing groin surgical site infections in patients who are obese and /or diabetic having vascular surgery.
- Conditions
- Obesity, Diabetes, Peripheral Vascular Disease
- Trial name
- NCT01983215
- Testing
- Prevena vac
- Where
- United States
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Dr. Jean E. Starr, MD
Artery Disease, Peripheral, Aortic Diseases
Relationship Between Morbimortality and Basal Activated Clotting Time (ACT) in Patients Undergoing Vascular Surgery
Check whether patients with higher comorbidity and risk of complication, estimated using the V (p) -POSSUM score, ACS NSQIP and the ASA classification, present higher baseline activated clotting time values.
- Conditions
- Artery Disease, Peripheral, Aortic Diseases, Carotid Artery Diseases, Other Disease
- Trial name
- NCT04703582
- Testing
- Activated clotting time
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Chronic Periodontitis, Atherosclerotic Cardiovascular Disease
Short-term Changes on C-Reactive Protein (CRP) Levels After Non-surgical Periodontal Treatment
The hypotheses tested were that levels of C-Reactive Protein (CRP) would be higher in patients with chronic periodontitis in comparison with those without periodontal disease and that the non-surgical periodontal treatment would…
- Trial name
- NCT01433744
- Testing
- Non-surgical periodontal treatment
- Where
- Brazil
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- State University of Maringá
Coronary Artery Bypass Grafting, Coronary Artery Disease
Comparison of RIMA-SVG and Ao-SVG Techniques in Coronary Artery Bypass Grafting
This randomized, double-blind, single-center clinical trial was divided into two groups, RIMA-SVG and Ao-SVG, according to the surgical method.
- Conditions
- Coronary Artery Bypass Grafting, Coronary Artery Disease, Saphenous Vein, Graft Patency
- Trial name
- NCT06787651
- Testing
- RIMA-SVG, Ao-SVG
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Second Hospital of Jilin University
Pelvic Organ Prolapse
Comparing Postoperative Pain After Vessel Sealing Device Versus Conventional Suturing Methods for Vaginal Hysterectomy and Pelvic Reconstructive Surgery
This study will investigate pain outcomes for patients undergoing vaginal hysterectomy with pelvic reconstructive surgery using the LigasureTM vessel sealing device as compared to conventional clamping and suturing methods.
- Trial name
- NCT05192954
- Testing
- LigaSureTM vessel sealing device
- Where
- 2 sites in United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Marlana McDowell
Incentive Spirometry, Oxygen Saturation
The Effects Incentive Spirometry Use in Coronary Artery Bypass Surgery
Background: Incentive spirometry is used in addition to care, especially in reducing pulmonary complications after surgery. Complications in the cardiovascular and pulmonary systems can basically be determined by blood values and…
- Trial name
- NCT05192785
- Testing
- Incentive Spirometry Group
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Hemostasis, Perioperative Bleeding
Appropriateness of Hemostatic Agent Use in Cardiovascular Surgery (HAEMOVAX)
Hemostatic agents are widely used in cardiac and vascular surgery to support intraoperative bleeding control. Despite their clinical relevance and substantial economic impact, little is known about real-world patterns of use…
- Conditions
- Hemostasis, Perioperative Bleeding, Cardiovascular Surgery, Cardiac Surgery
- Trial name
- HAEMOVAX (NCT07699016)
- Testing
- observational study
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Milan
Coronary Artery Disease, Atrial Fibrillation (AF)
Cardiovascular Innovation & Research Institute 's NEXUS Registry, the Whole is Greater Than the Parts.
Information gathered from the patients via a disease specific questionnaire will be married to data from the National Cardiovascular Data Registry (NCDR®).
- Trial name
- NCT03428048
- Testing
- Hybrid procedure, Endocardial ablations, left atrial appendage occlusion
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Cardiovascular Innovation and Research Institute
Cardiac Surgical Procedures, Coronary Artery Disease
Clinical Outcomes in Patients Treated With SternaLock Blu
The primary objective of this study is to evaluate the rate of deep sternal wound infection at 30 days post-operative following a full median sternotomy in patients treated with SternaLock Blu for rigid sternal fixation.
- Conditions
- Cardiac Surgical Procedures, Coronary Artery Disease, Heart Valve Diseases
- Trial name
- SECURE (NCT03709693)
- Testing
- SternaLock Blu
- Where
- 4 sites in United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
MRSA - Methicillin Resistant Staphylococcus Aureus Infection
Vascular Surgical Antibiotic Prophylaxis Study (VSAPS 2)
The current recommended antibiotic, Cefazolin, treatment for vascular surgery, provides coverage only for Methicillin-Sensitive Staphylococcus Aureaus (MSSA), other gram-positive bacteria, and some gram-negative bacteria which…
- Trial name
- NCT01612052
- Testing
- Antibiotic Prophylaxis
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- CAMC Health System
Analgesia, Obstetrical, Postpartum Hemorrhage
Prospective Effect of Intravenous Ketorolac on Opioid Use, EBL and Complications Following Cesarean Delivery
In this randomized, double-blind control trial to evaluate the effect of ketorolac given at the time of cord clamp has on estimated blood loss and postcesarean pain control.
- Conditions
- Analgesia, Obstetrical, Postpartum Hemorrhage, Opioid Use, Nonsteroidals (NSAIDs)Toxicity
- Trial name
- NCT02509312
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Hemorrhoids, Fissure in Ano
Multi-Drug Analgesia vs. Standard Solution for Anal Surgery
The primary aim is to test the magnitude and duration of analgesia provided by single dose multi-drug analgesia administered for perianal block, and compare with standard solution (Marcaine \& Lidocaine in 1:1 mixture - Total 60…
- Conditions
- Hemorrhoids, Fissure in Ano, Fistula;Rectal
- Trial name
- NCT03105674
- Testing
- Multi-drug local anesthetics (Combination), Standard local anesthetics (Combination)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Columbia University
Acute Kidney Injury, Hypotension
Is Permissive Hypotension Truly Harmless? Early Biomarker Evidence of Subclinical Kidney Injury in Rhinologic Surgery
This study aims to investigate the effects of permissive hypotension, which is routinely used in rhinologic surgeries such as rhinoplasty, septoplasty, and functional endoscopic sinus surgery (FESS), on renal function.
- Trial name
- NCT07328620
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Gazi University
Critical Limb Threatening Ischaemia, Depression Disorder
Symptoms of Anxiety and/or Depression and SDM in Older Patients With CLTI
Mental health disorders are common in older people and are often unrecognised. Those living with mental health disorders who are being considered for vascular surgery have worse post operative outcomes, including longer length of…
- Conditions
- Critical Limb Threatening Ischaemia, Depression Disorder, Anxiety
- Trial name
- NCT07529886
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Patient Care Team, Coronary Artery Disease
Developing an Intervention to Improve the Non-Technical Skills of the Cardiac Surgical Teams
Teams of several medical professionals conduct high-risk cardiac surgical procedures. These professionals work in complex, stressful operating room environments requiring effective communication and teamwork skills.
- Conditions
- Patient Care Team, Coronary Artery Disease, Coronary Artery Bypass, Surgery
- Trial name
- NCT06257511
- Testing
- Simulation-Based Mastery Learning of the Non-technical skills
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University