Clinical trials: Veterans
Mental Illness, Physical Illness
Evaluation of Peer Specialists on VA PACTs
In August 2014, the White House issued an Executive Action mandating that 25 VA medical centers place Peer Specialists (Veterans recovered from mental illness who are trained to support other Veterans with mental illness) on…
- Trial name
- Peers on PACT (NCT02732600)
- Testing
- Facilitated Implementation
- Where
- 25 sites in United States
- Volunteers
- 5,616 people
- Sponsor
- VA Office of Research and Development
Cigarette Smoking
Improving the Delivery of Smoking Cessation Guidelines in Hospitalized Veterans
The primary objective of this study is to determine whether a nurse-initiated intervention, which couples brief inpatient counseling and proactive telephone counseling by a centralized tobacco quitline, improves 6-month cessation…
- Trial name
- NCT00816036
- Testing
- Smoking Cessation Guideline Implementation
- Where
- 4 sites in United States
- Volunteers
- 898 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Colorectal Cancer
Text Messaging to Improve Adherence To Repeat Colonoscopy In a Veterans Affairs (VA) Hospital
Colorectal cancer is a common but preventable condition, and increasing colorectal cancer screening is one of the most impactful public health contributions in the field of gastroenterology.
- Trial name
- NCT06185374
- Testing
- Text Message Instructions/Motivation
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Posttraumatic Stress Disorder, Moral Injury
Pilot Study Testing a Web-Based Moral Elevation Intervention for Veterans With PTSD and Moral Injury
Given the prevalence of posttraumatic stress disorder (PTSD) and moral injury in combat Veterans and the limitations to current treatments, novel approaches are needed to target both PTSD and moral injury and directly impact…
- Trial name
- NCT03906240
- Testing
- Moral Elevation intervention
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- VA Office of Research and Development
Occupational Exposure
High-Intensity Interval Training to Improve Symptoms of Deployment-Related Respiratory Disease
Some military personnel who have been exposed to burn pit emissions, desert dust, and other airborne hazards experience new respiratory symptoms after deployment.
- Trial name
- NCT05849168
- Testing
- Exercise training
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of Colorado, Denver
Stress Disorder, Post Traumatic
D-cycloserine and Virtual Reality Exposure to Treat Iraq War Veterans With PTSD
This study will determine whether a combination of virtual reality exposure therapy and D-cycloserine will reduce post-traumatic stress disorder symptoms in Iraq war veterans.
- Trial name
- NCT00356278
- Testing
- D-Cycloserine, Alprazolam, Virtual Reality Exposure Therapy
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Emory University
Posttraumatic Stress Disorder
PROlonGed ExpoSure Sertraline
The current research study aims to compare the effectiveness of two proven treatments for posttraumatic stress disorder (PTSD): Prolonged Exposure (PE), sertraline, and their combination.
- Trial name
- PROGrESS (NCT01524133)
- Testing
- Sertraline, Prolonged Exposure Therapy
- Where
- 4 sites in United States
- Volunteers
- 223 people
- Sponsor
- VA Ann Arbor Healthcare System
Traumatic Brain Injury
ACTIVE: Activity Therapy to Increase Veteran Engagement
Depression is common after traumatic brain injury (TBI) and may have wide-ranging consequences. Post-TBI depression may impede reintegration into the family and community and lead to lower quality of life and heightened suicide…
- Trial name
- ACTIVE (NCT04976621)
- Testing
- Behavioral Activation, Treatment as Usual
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- VA Office of Research and Development
Prostate Cancer
Vitamin D Supplementation in Veterans With Early-Stage Prostate Cancer
Vitamin D promotes the differentiation of prostate cancer cells, maintains the differentiated phenotype of prostate epithelial cells, and can induce prostate cancer cell death, raising the possibility that vitamin D deficiency…
- Trial name
- vit D & PCa (NCT00953225)
- Testing
- vitamin D3
- Where
- 2 sites in United States
- Volunteers
- 83 people
- Sponsor
- VA Office of Research and Development
Well-being
Develop and Validation of Measurement-Based Transition Assistance
Although some Veterans seek help when they experience post-military readjustment challenges, many do not. One factor that stands in the way of Veterans' willingness to seek help for these challenges is their lack of knowledge…
- Trial name
- MBTA (NCT05384171)
- Testing
- Measurement-Based Transition Assistance (MBTA)
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- VA Office of Research and Development
Frailty
Prehabilitation of Veterans With Exercise and Nutrition
The goal of VA's RR\&D office is to maximize functional recovery. This proposal will allow the investigators to test an intervention that combines the fundamentals of Physical Medicine and Rehabilitation with state-of-the-art…
- Trial name
- PREVENT (NCT04485611)
- Testing
- Supervised aerobic + resistance training and nutritional support
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Chronic Pain, Gulf War Illness
Treating Chronic Pain in Gulf War Illness
The purpose of this study is to determine whether yoga is effective for the treatment of chronic pain in Gulf War Illness.
- Conditions
- Chronic Pain, Gulf War Illness, Chronic Illness
- Trial name
- NCT02378025
- Testing
- Yoga Group, Pain Management Wellness Group
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Palo Alto Veterans Institute for Research
Anxiety, Depression
Improving Obesity Self-Care Among Mentally Ill Veterans
The purpose of this study is to find out which of two programs, MH MOVE! or the enhanced usual care MOVE! program is most effective in improving participation in and completion of MOVE! among Veterans with depression, anxiety…
- Conditions
- Anxiety, Depression, PTSD, Obesity
- Trial name
- MH MOVE! (NCT02642536)
- Testing
- MH MOVE, Enhanced Usual Care
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- VA Office of Research and Development
Persian Gulf Syndrome
Acupuncture in the Treatment of Gulf War Illness
This unblinded Phase II clinical trial tested the effects of individualized acupuncture treatments offered in extant acupuncture practices in the community; practitioners had at least 5 years of experience plus additional…
- Trial name
- NCT01305811
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- New England School of Acupuncture
Low Back Pain
Selecting Effective Combinations of Treatment for Low Back Pain
Back pain is the #1 contributor to disability in the United States (US), and second only to hearing problems as a reason for new Veteran disability compensation.
- Trial name
- SELECT LBP (NCT03520387)
- Testing
- Lumbar medial branch nerve radiofrequency ablation (LRFA), Simulated LRFA with targeted steroid injections, AcTIVE-CBT
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- VA Office of Research and Development
Gulf War Veterans' Illness
CAM in Veterans With Gulf War Illnesses
The purpose of this study is to explore the effectiveness Gulf War Health Education (GWHE) and iRest Yoga Nidra (mindfulness meditation)/auricular (ear) acupuncture for Veterans with Gulf War Veterans' Illnesses (GWVI).
- Trial name
- GW-CAM (NCT02180243)
- Testing
- Mindfulness meditation/Acupuncture, Gulf War Health Education
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- VA Office of Research and Development
Transplant
Improving Transplant Medication Safety Through A Technology and Pharmacist Intervention
Medication safety issues in Veteran organ transplant recipients, including side effects and errors, are a major issue leading to graft failure and death.
- Trial name
- ISTEP (NCT03860818)
- Testing
- Health services delivery
- Where
- United States
- Volunteers
- 2,196 people
- Sponsor
- VA Office of Research and Development
Tobacco Dependence, Veterans
Identifying Effective Treatment for Veterans Unwilling to Quit Smoking
This project will generate knowledge about the effectiveness of Enhanced Chronic Care, an intervention designed to enhance treatment use and smoking abstinence in Veterans who are initially unwilling to quit.
- Trial name
- NCT04061720
- Testing
- Enhanced Chronic Care, Standard Care
- Where
- United States
- Volunteers
- 502 people
- Sponsor
- VA Office of Research and Development
Post Traumatic Stress Disorders
Can Service Dogs Improve Activity and Quality of Life in Veterans With PTSD?
Service Dogs are trained to assist people with disabilities to accomplish tasks which permit the individual to be more functional in their home and social environment.
- Trial name
- SDPTSD (NCT02039843)
- Testing
- Emotional Support Dogs, Service Dogs
- Where
- 4 sites in United States
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Prostatic Neoplasms
A Study to Learn About Novel Hormonal Therapies (NHTs) for Metastatic Castration-sensitive Prostate Cancer (mCSPC) in People Who Were in the Armed Forces
The purpose of this study is to learn about- for how long are NHTs taken by men to treat mCSPC. NHTs in this study include study medicines: abiraterone, apalutamide, enzalutamide.
- Trial name
- NCT06151418
- Testing
- Novel hormonal therapy
- Where
- United States
- Volunteers
- 2,313 people
- Sponsor
- Pfizer