Clinical trials: Viral Pneumonia
Pneumonia, Viral, COVID-19 Pneumonia
AI-based System for Assessing Suspected Viral Pneumonia Related Lung Changes
The AI-based system designed to process chest computed tomography (CT) aims to 1) detect the presence of pathologic patterns associated with interstitial changes in pneumonia; 2) highlight areas on the images with the probable…
- Trial name
- NCT06501599
- Testing
- Medical software (AI-based system)
- Where
- Russia
- Volunteers
- 563 people, healthy volunteers welcome
- Sponsor
- Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department
Pneumonia, Viral
Study on Efficacy and Safety of Reparixin in the Treatment of Hospitalized Patients With Severe COVID-19 Pneumonia.
The study objective is to assess Efficacy and safety of Reparixin treatment as compared to placebo (both on top of standard treatment) in adult patients with severe COVID-19 pneumonia.
- Trial name
- NCT04878055
- Testing
- Reparixin
- Where
- 17 sites in United States, Italy
- Volunteers
- 287 people
- Sponsor
- Dompé Farmaceutici S.p.A
Covid19
"Efesovir" (FS-1) for COVID-19, Phase 2
Study of the efficacy and safety of the new drug "Efesovir" in comparison with the drug "Remdesivir" in the treatment of patients hospitalized with COVID-19.
- Trial name
- NCT05060705
- Testing
- Efesovir
- Where
- Kazakhstan
- Volunteers
- 62 people
- Sponsor
- Scientific Center for Anti-infectious Drugs, Kazakhstan
COVID-19, Respiratory Tract Infections
Tobacco Use and the Risk of COVID-19 and Adverse Outcomes
This is an observational study of pooled population-based samples in three Nordic countries. Country-specific data has already been analysed in previous studies in Sweden, Finland, and Norway.
- Conditions
- COVID-19, Respiratory Tract Infections, Infections, Pneumonia, Viral
- Trial name
- NCT05321433
- Where
- Sweden
- Volunteers
- 757,585 people
- Sponsor
- Karolinska Institutet
Pneumonia, Pneumonia, Viral
Diagnostic Accuracy of Pocket-size Lung Ultrasound in Pneumonia Etiology and Complications in Hospitalized Children
1. Background and study aims Pneumonia is the leading infectious cause of death in children worldwide. Although the diagnosis is clinical, a chest radiograph (CXR) is often necessary to clarify it, exposing the patient to…
- Conditions
- Pneumonia, Pneumonia, Viral, Pneumonia, Bacterial
- Trial name
- POCUS-L (NCT06296693)
- Testing
- Pocket-size lung ultrasound for etiological definition of pneumonia and surveillance of complications in children hospitalized
- Volunteers
- 76 people
- Sponsor
- Centro Hospitalar Universitário de Santo António
COVID-19 Infection
A Trial Looking at the Use of Camostat in People Who Have Tested Positive for Coronavirus (COVID-19) (SPIKE-1)
This is a phase II randomised, multicentre, prospective, open label clinical trial. The trial aims to recruit patients who test positive for COVID-19 who have mild symptoms and therefore can treat their symptoms in the community.
- Trial name
- SPIKE-1 (NCT04455815)
- Testing
- Camostat
- Where
- 9 sites in United Kingdom
- Volunteers
- 34 people
- Sponsor
- Cancer Research UK
Infection Viral, Coronavirus
PREdiction of DIagnosed Covid-19 infecTion in IUC Patients
Coronavirus 2019 (COVID-19) is a respiratory tropism virus transmitted through droplets emitted into the environment of infected persons.
- Conditions
- Infection Viral, Coronavirus, ARDS, Pneumonia
- Trial name
- PREDICT (NCT04327180)
- Where
- France
- Volunteers
- 368 people
- Sponsor
- University Hospital, Lille
COVID-19, Pneumonia, Viral
Effectiveness of Covid-19 Vaccination in Eswatini Against SARS-CoV-2 Associated Hospitalization and Death
Since late December 2019, the novel human coronavirus (SARS-CoV-2) first reported in China, has spread worldwide. Vaccines to prevent SARS-CoV-2 infections have been developed in record time and several candidate vaccines have…
- Trial name
- NCT04914832
- Testing
- AZD1222
- Where
- Eswatini
- Volunteers
- 75,012 people, healthy volunteers welcome
- Sponsor
- Shabir Madhi
Covid19, SARS (Severe Acute Respiratory Syndrome)
Double-Blind, Randomized, Placebo-Controlled, Multi-Center Phase 3 Study to Evaluate the Efficacy and Safety of Fostamatinib in COVID-19 Subjects
The study is a double-blind, randomized, placebo-controlled, multi-center, Phase 3 study to evaluate the efficacy and safety of fostamatinib in COVID-19 subjects.
- Conditions
- Covid19, SARS (Severe Acute Respiratory Syndrome), SARS Pneumonia, SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere
- Trial name
- NCT04629703
- Testing
- Fostamatinib
- Where
- 47 sites in United States, Argentina and 2 more
- Volunteers
- 280 people
- Sponsor
- Rigel Pharmaceuticals
Complication of Medical Care, Pneumonia, Viral
Antiviral Drugs on the Treatment of SARS-CoV-2
Retrospective Non-Randomized Analytical Cohort Study of Completed SARS-CoV2 COVID19 Cases
- Trial name
- FavRem (NCT04727775)
- Testing
- Favipiravir, Remdesivir
- Where
- 2 sites in Kazakhstan
- Volunteers
- 150 people
- Sponsor
- Astana Medical University
COVID, SARS-CoV 2
Characteristics of Patients With COVID-19 in Meta State, Colombia
This observational study aims to collect detailed clinical information on confirmed or suspected patients of COVID-19 treated in hospitals from Meta State, Colombia. The objectives are: 1.
- Conditions
- COVID, SARS-CoV 2, SARS Pneumonia, SARS (Disease)
- Trial name
- NCT04456426
- Sponsor
- Hospital Departamental de Villavicencio
Influenza, Pneumonia
Rapid Empiric Treatment With Oseltamivir Study (RETOS)
Current guidelines recommend early initiation of empiric antibiotic therapy to cover typical and atypical bacteria that may cause community-acquired pneumonia (CAP).
- Trial name
- RETOS (NCT01248715)
- Testing
- oseltamivir
- Where
- 5 sites in United States
- Volunteers
- 1,107 people
- Sponsor
- University of Louisville
COVID-19
Study Evaluating Diltiazem in Combination With Standard Treatment in the Management of Patients Hospitalized With COVID-19 Pneumonia
SARS-CoV-2 infection is responsible for hypoxemic pneumonia, which is sometimes serious and associated with excess mortality. To date, with the exception of dexamethasone, which has shown clinical efficacy by reducing the…
- Trial name
- DICOV (NCT05563168)
- Where
- 21 sites in France
- Sponsor
- Hospices Civils de Lyon
SARS-CoV2 Infection
Characteristics of Critically Ill Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection (COVID-19)
A multicenter observational, prospective cohort study that consisted of a large-scale data source of hospital ICU admissions and patient-level clinical data in Spain.
- Trial name
- GETCOV-2 (NCT04948242)
- Where
- Spain
- Volunteers
- 5,000 people
- Sponsor
- Hospital Universitari Joan XXIII de Tarragona.
Rehabilitation, Pneumonia, Viral
Rehabilitation Treatment of Patients With COVID-19
This is single centre retrospective study with propensity score matching. The aim of the study is to develop criteria for determining groups of patients with a new coronavirus infection based on clinical, laboratory and…
- Conditions
- Rehabilitation, Pneumonia, Viral, COVID-19, Quality of Life
- Trial name
- COVID-REHAB (NCT05808361)
- Testing
- exercises, massage
- Where
- Russia
- Volunteers
- 180 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Pneumonia, Viral, Covid19
Diaphragmatic Echography in COVID-19 Pneumonia
We hypothesized that diaphragm thickness is concerned in acute respiratory failure of COVID19 patients and its ultrasound measure at the begining of hospitalisation is a good predictor of poor outcome.
- Conditions
- Pneumonia, Viral, Covid19, Respiratory Failure
- Trial name
- COVIDUSDIAP (NCT05805579)
- Testing
- Diaphragmatic echography
- Where
- Spain
- Volunteers
- 171 people
- Sponsor
- Javier Lázaro
Viral Pneumonia
PTH - Preemptive Treatment for Herpesviridae
The aim of this study is to show that a preemptive treatment by ganciclovir (for positive CMV viremia) or aciclovir (for positive HSV oro-pharyngeal PCR) is able to increase the number of ventilator-free days at Day 60.
- Trial name
- PTH (NCT02152358)
- Testing
- Aciclovir, Ganciclovir
- Where
- France
- Volunteers
- 317 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Covid19, Hyperactive Delirium
Valproate Alone or in Combination With Quetiapine for Severe COVID-19 Pneumonia With Agitated Delirium
The primary purpose of this research is to determine whether Valproate alone, and in combination with Quetiapine, lowers confusion and agitation in persons with severe Corona Virus Disease (COVID)19 pneumonia during weaning from…
- Conditions
- Covid19, Hyperactive Delirium, Pneumonia, Viral
- Trial name
- NCT04513314
- Testing
- Valproate, Quetiapine, Standard of Care
- Sponsor
- University of Miami
COVID-19, Acute Respiratory Distress Syndrome
DEXamethasone EARLY Administration in Hospitalized Patients With Covid-19 Pneumonia
The aim of this study is to evaluate the efficacy of dexamethasone in hospitalized adults with COVID-19 pneumonia who do not require supplementary oxygen on admission, but have high risk of developing acute respiratory distress…
- Conditions
- COVID-19, Acute Respiratory Distress Syndrome, Pneumonia, Viral
- Trial name
- EARLYDEXCoV2 (NCT04836780)
- Testing
- Dexamethasone
- Where
- 3 sites in Spain
- Volunteers
- 126 people
- Sponsor
- Hospital Universitario Infanta Leonor
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Coronavirus Disease 2019 (COVID-19)
A Study to Learn About the Medicine Called Nirmatrelvir Used in Combination With Ritonavir in People With Weakened Immune Systems or at Increased Risk for Poor Outcomes Who Are Hospitalized Due to Severe COVID-19
A Study to Learn About the Medicine Called Nirmatrelvir Used in Combination With Ritonavir in People with Weakened Immune Systems or at Increased Risk for Poor Outcomes who are Hospitalized Due to Severe COVID-19
- Conditions
- Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Coronavirus Disease 2019 (COVID-19), Immunocompromised, Hospitalization
- Trial name
- EPIC-HOS (NCT05545319)
- Testing
- Nirmatrelvir, Ritonavir
- Where
- 11 sites in United States, Bulgaria
- Sponsor
- Pfizer