Clinical trials: Vision Impairment and Blindness
Vision Loss Partial, Vision; Loss, Both Eyes
Effect of Visual Retraining After Stroke
This project is intended to collect data using standard clinical tests and psychophysics to quantify the effect of visual cortical damage on the structure of the residual visual system, visual perception, spatial awareness, and…
- Conditions
- Vision Loss Partial, Vision; Loss, Both Eyes, Hemianopia Homonymous, Hemianopia
- Trial name
- urochester (NCT06121219)
- Testing
- Training in the Blind Field
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Retinal Degeneration, Vision Impairment and Blindness
Multicenter Study of Transcranial Magnetic Stimulation on Vision Restoration
The goal of this clinical trial is to learn if transcranial magnetic stimulation (TMS) works to restore vision in adults with severe retinal degeneration. It will also learn about the safety of TMS treatment.
- Trial name
- NCT07425717
- Testing
- Transcranial magnetic stimulation targeting occipital visual cortex
- Where
- 4 sites in China
- Volunteers
- 136 people
- Sponsor
- Shanghai High Myopia Study Group
Cerebral Visual Impairment
A Computerized, Adaptive Therapeutic Gaming Approach Training Visual Perceptual Skills in Children With CVI
This clinical trial aims to compare the effectiveness of our adaptive, therapeutic game to the effectiveness of the same game, without the adaptive component.
- Trial name
- iVision2_WP3 (NCT05014503)
- Testing
- Adaptive Therapeutic gaming, Non-adaptive Therapeutic gaming
- Where
- Belgium
- Volunteers
- 73 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Retinopathy of Prematurity (ROP), Prematurity Complications
Retinopathy of Prematurity - Visual Function and Retinal Structure
Children born prematurely may develop a characteristic retinal disease named retinopathy of prematurity (ROP). This disease could lead to retinal detachment and blindness.
- Conditions
- Retinopathy of Prematurity (ROP), Prematurity Complications, Cerebral Visual Impairment, Visual Field Defect
- Trial name
- NCT07427719
- Where
- Norway
- Volunteers
- 140 people
- Sponsor
- Oslo University Hospital
Stroke, CVA (Cerebrovascular Accident)
MORbidity PRevalence Estimate In StrokE
Information regarding the likely progress of post-stroke symptoms is vitally important to stroke survivors to allow them to plan for the future and to adjust to life after stroke.
- Conditions
- Stroke, CVA (Cerebrovascular Accident), CVA; Sequelae, Stroke, Ischemic
- Trial name
- MORe PREcISE (NCT03605381)
- Where
- 3 sites in United Kingdom
- Volunteers
- 500 people
- Sponsor
- Aneurin Bevan University Health Board
Hemianopia, Visual Field Defect Following Cerebrovascular Accident
Screening and Rehabilitation of Visual Field Defects in Post-Stroke Patients
In this study, the investigators will use a wearable device capable of performing this bedside assessment to evaluate the incidence of visual field loss in post-stroke patients.
- Trial name
- SCRiCaViPS (NCT07317739)
- Testing
- Early multisensory audio-visual stimulation training, Early visual field test
- Volunteers
- 300 people
- Sponsor
- Fondazione David Chiossone - Impresa Sociale
Visual Field Defect, Peripheral, Stroke
Improving Visual Field Deficits With Noninvasive Brain Stimulation
This is a randomized, pilot interventional study in participants with visual field deficit (VFD) caused by cortical lesion. Damage to the primary visual cortex (V1) causes a contra-lesional, homonymous loss of conscious vision…
- Conditions
- Visual Field Defect, Peripheral, Stroke, Visual Impairment, Hemianopsia
- Trial name
- NCT05085210
- Testing
- transcranial random noise stimulation (tRNS), Computer Based Visual Training, Virtual Reality Based Visual Training
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Beth Israel Deaconess Medical Center
Central Visual Impairment
Training Oculo-motor Control to Improve Vision When Using a Preferred Retinal Locus
When high-detail vision is lost due to a retinal disease such as macular degeneration, people see poorly, and have difficulty with eye movements (oculo-motor control).
- Trial name
- NCT05637385
- Testing
- Training of perception and oculo-motor control
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Russell L. Woods
Retinitis Pigmentosa, Usher Syndrome Type 2
Study to Evaluate the Efficacy Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene With Early to Moderate Vision Loss (Celeste)
The purpose of this study is to evaluate the efficacy safety and tolerability of QR-421a administered via intravitreal injection (IVT) in subjects with Retinitis Pigmentosa (RP) due to mutations in exon 13 of the USH2A gene with…
- Conditions
- Retinitis Pigmentosa, Usher Syndrome Type 2, Deaf Blind, Retinal Disease
- Trial name
- NCT05176717
- Testing
- QR-421a
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 5 people
- Sponsor
- Laboratoires Thea
Stroke Induced Vision Loss, Hemianopia
Visual Restoration for Hemianopia
The purpose of this research is to assess the efficacy of a visual training task on reducing the size of a visual field deficit caused by brain damage in adults, and its ability to improve visual functions in this patient…
- Conditions
- Stroke Induced Vision Loss, Hemianopia, Quadrantanopia
- Trial name
- NCT03350919
- Testing
- Training in the blind field, Training in the intact field
- Where
- 3 sites in United States
- Volunteers
- 48 people
- Sponsor
- University of Rochester
Endothelial Dysfunction, Sublingual Capillary Glycocalyx and Density
Prematurity as Predictor of Children's Cardiovascular-renal Health
Extreme preterm birth interferes with the development of the cardiovascular system. Both macro- as well as microvasculature undergoes extensive, organ specific maturation.
- Conditions
- Endothelial Dysfunction, Sublingual Capillary Glycocalyx and Density, Visual Disturbances and Blindness, Ventricular Dysfunction, Left
- Trial name
- PREMATCH (NCT02147457)
- Where
- Belgium
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Visual Rehabilitation, Oddball Design
In-person and Telehealth Visual Rehabilitation for Children With Low Vision
Restorative visual rehabilitation is frequently used to enhance the visual development and function of children with low vision.
- Conditions
- Visual Rehabilitation, Oddball Design, Cerebral Visual Impairment, Passive Visual Stimulation
- Trial name
- NCT06701617
- Testing
- restorative visual rehabitation
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Blindness Congenital
Comparison of Balance and Coordination Parameters of Visually Impaired and Healthy Individuals
The aim of this [observational study] is to examine balance in multiple aspects by comparing balance, coordination, and gait parameters between congenitally blind individuals and healthy individuals with multiple scales.
- Trial name
- NCT06687915
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Blindness
The Impact of Rehabilitation on Quality of Life in Visually Impaired
The project has four primary objectives: 1) Determine if blind rehabilitation improves the quality of life of legally blind veterans; 2) Determine the relationship between quality of life and visual function; 3) Determine if…
- Trial name
- NCT00013403
- Testing
- Blindness
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- US Department of Veterans Affairs
Cerebral Palsy, Visual Impairment
Turkish Validity and Reliability of the Visual Function Classification System (VFCS)
Cerebral Palsy (CP) is the most common childhood disorder that occurs with a lesion in the developing infant brain, seen in 2-3/1000 live births.
- Conditions
- Cerebral Palsy, Visual Impairment, Visual Disorder, Cerebral Visual Impairment
- Trial name
- NCT05102955
- Testing
- Observational questionnaires
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Macular Degeneration
Vascular Endothelial Growth Factor (VEGF) Trap-Eye: Investigation of Efficacy and Safety in Wet Age-Related Macular Degeneration (AMD)
This study is a phase III, double-masked, randomized, study of the efficacy and safety of VEGF Trap-Eye in patients with neovascular age-related macular degeneration.
- Trial name
- VIEW 2 (NCT00637377)
- Testing
- Ranibizumab, Aflibercept Injection (EYLEA, VEGF Trap-Eye, BAY86-5321)
- Where
- 189 sites in Argentina, Australia and 24 more
- Volunteers
- 1,240 people
- Sponsor
- Bayer
Feeding Behavior, Sensory Integration Disorder
Feeding Behavior Intervention in Children with Cerebral Visual Impairment
This study was planned to investigate the effects of nutritional education given in addition to sensory integration intervention on feeding behavior, sensory processing and developmental areas in children with Cerebral Visual…
- Conditions
- Feeding Behavior, Sensory Integration Disorder, Cerebral Visual Impairment
- Trial name
- NCT06827743
- Testing
- feeding behavior education, Sensory integration intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Trakya University
Visual Impairment, Cerebral Visual Impairment
VIPPSTAR-G1 Digital Early Intervention for Visual Impairment
Visual impairment in infancy is associated with significant risks for neurodevelopmental impairment. Early intervention based on enriched visual and multisensory experiences may promote neuroplasticity and improve developmental…
- Conditions
- Visual Impairment, Cerebral Visual Impairment, Neurodevelopmental Disorders, Prematurity
- Trial name
- VIPPSTAR-G1 (NCT07717671)
- Testing
- VIPPSTAR Digital Early Intervention, Standard Clinical Care
- Where
- 5 sites in Belgium, Italy and 1 more
- Volunteers
- 150 people
- Sponsor
- Università degli Studi di Brescia
Blindness
Sensory Substitution and Brain Plasticity Following Vision Loss
The goal of this clinical investigation is to learn how the brain responds when visual information is converted into patterns of sound or touch in blind and sighted participants.
- Trial name
- SenSubMRI (NCT07450677)
- Testing
- Electrotactile display (BrainPort), Vision-to-sound converter (AI Sight)
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Stanford University
Vision Loss Partial, Vision; Loss, Both Eyes
Understanding Visual Processing After Occipital Stroke
The purpose of this study is to investigate how visual orientation discrimination and metacognition (i.e., perceptual confidence) are affected by occipital stroke that causes hemianopia and quadrantanopia in adults.
- Conditions
- Vision Loss Partial, Vision; Loss, Both Eyes, Hemianopia, Homonymous, Hemianopia
- Trial name
- NCT06352086
- Sponsor
- University of Rochester