Clinical trials: Visual Outcome
Hypoxic-Ischemic Encephalopathy, Neonatal Encephalopathy
Healthy Little Eyes
The purpose of this research study is to gather more information on how eye injury is related to a baby's future development and see if eye function and brain test results can be used, along with current measures, to better…
- Conditions
- Hypoxic-Ischemic Encephalopathy, Neonatal Encephalopathy, Encephalopathy
- Trial name
- NCT05971446
- Testing
- Visual Evoked Potential (VEP), Electroretinogram (ERG)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Appendicolith, Appendicitis
Laparoscopic Appendectomy Performed by Junior SUrgeonS: Impact of 3D Visualization on Surgical Outcome
Laparoscopy has revolutionized the approach to a number of surgical problems causing a re-evaluation of several clinical strategies.
- Conditions
- Appendicolith, Appendicitis, Appendicitis With Perforation, Appendicitis Peritonitis
- Trial name
- LAPSUS (NCT03770897)
- Testing
- 3D Laparoscopic Appendectomy, 2D Laparoscopic Appendectomy
- Where
- Italy
- Volunteers
- 128 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Preterm Less Than 32wks With IVH, WMI/PVL, Late Preterm or Term (37-42wks) With Neonatal Encephalopathy Treated With Hypothermia for HIE
Cerebral/ Cortical Visual Impairment: Screening, Identification and Outcome Prediction in Neonates
Cerebral/Cortical Visual Impairment (CVI) is the leading cause of childhood visual impairment in the United States and other industrialized countries.
- Trial name
- CVI (NCT07275021)
- Testing
- Prospective Clinical and Neurodevelopmental Data Collection
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Brigham and Women's Hospital
Age-related Macular Degeneration, Polypoidal Choroidal Vasculopathy
Visual Outcome in Patients With Symptomatic Macular Polypoidal Choroidal Vasculopathy (PCV) Treated With Either Ranibizumab as Monotherapy or Combined With Verteporfin Photodynamic Therapy (vPDT)
This study compared the effect of ranibizumab administered as monotherapy versus ranibizumab administered in combination with verteporfin photodynamic therapy (PDT) on visual acuity in patients with symptomatic macular polypoidal…
- Trial name
- EVEREST II (NCT01846273)
- Testing
- Ranibizumab, Verteporfin PDT
- Where
- 41 sites in Hong Kong, Japan and 5 more
- Volunteers
- 321 people
- Sponsor
- Novartis Pharmaceuticals
Pituitary Tumor, Optic Chiasm Disorder
Visual Outcome After Transsphenoidal Surgery for Pituitary Macroadenoma
Endoscopic endonasal transsphenoidal surgery is a procedure for the treatment of pituitary macroadenomas that cause visual impairment through optic chiasm compression.
- Trial name
- RetroADEN (NCT03363126)
- Testing
- Endonasal transsphenoidal pituitary tumor removal
- Volunteers
- 88 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Age Related Macular Degeneration, Diabetic Macular Edema
Cytokine and Visual Outcome Variations in Eyes Receiving Aflibercept
Objective: To determine the association between baseline aqueous cytokine levels and treatment intervals for patients under a variable dosing regimen with intravitreal aflibercept in patients with neovascular age-related macular…
- Conditions
- Age Related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion, Macular Edema
- Trial name
- COVARIANT (NCT03056079)
- Testing
- Intravitreal aflibercept
- Where
- 2 sites in Canada
- Volunteers
- 168 people
- Sponsor
- Unity Health Toronto
Attention, Visual Perceptual Weakness
Result of tDCS in ASD Children With Comorbidities Like PANDAS, Rare Genetic Diseases or Autoimmune Disorders
Results of the application of 100 sessions of tDCS for 12 months in children between 6 and 11 years old with autism spectrum disorder with rare diseases, genetic problems or PANDAS
- Conditions
- Attention, Visual Perceptual Weakness, Social Behavior, Fluency Disorder
- Trial name
- tDCS&ASD (NCT06368726)
- Testing
- tDCS or Transcranial Direct Current Stimulation, Risperidone
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Spanish Foundation for Neurometrics Development
Cataract
Clinical Outcome After Implantation of Two Different Multifocal Toric IOLs: Liberty (677MTY) and PanOptix®
This study is to compare the rotational stability, visual outcome and patient satisfaction after implantation with either Liberty 677MTY, a multifocal diffractive-refractive IOL based on EPS technology manufactured by Medicontur…
- Trial name
- NCT05895396
- Where
- Hungary
- Volunteers
- 35 people
- Sponsor
- Medicontur Medical Engineering Ltd
Age Related Macular Degeneration, Diabetic Macular Edema
Cytokine and Visual Outcome Variations in Eyes Receiving Ranibizumab
Objective: To determine the association between baseline aqueous cytokine levels and treatment intervals for patients under a variable dosing regimen with intravitreal ranibizumab in patients with neovascular age-related macular…
- Conditions
- Age Related Macular Degeneration, Diabetic Macular Edema, Macular Edema, Retinal Vein Occlusion
- Trial name
- COVERT (NCT03056092)
- Testing
- Intravitreal ranibizumab
- Where
- 2 sites in Canada
- Volunteers
- 168 people
- Sponsor
- Unity Health Toronto
Retinitis Pigmentosa
A Study of Encapsulated Cell Technology (ECT) Implant for Participants With Early Stage Retinitis Pigmentosa
The purpose of this study is to look at the safety and effectiveness of CNTF implants on vision in persons with retinitis pigmentosa, Usher type II \& III, and Choroideremia.
- Trial name
- NCT00447980
- Testing
- NT-501
- Where
- 12 sites in United States
- Volunteers
- 73 people
- Sponsor
- Neurotech Pharmaceuticals
Visual To Compare the Visual Outcome Between AcrySof™ IQ Vivity™ and TECNIS Synergy™ Intraocular Lens (Model ZFR00V )
A Comparative Study of Visual Outcome of Two Extended Depth of Focus Intraocular Lenses After Cataract Surgery
The investigators aim to compare the visual performance of the most recently introduced extended depth of focus intraocular lenses ; AcrySofTM IQ VivityTM and TECNIS SynergyTM ( an extended depth of focus IOL ) regarding the…
- Trial name
- NCT05647421
- Testing
- IOL implantation
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Macular Edema Due to BRVO/CRVO
Ranibizumab Treatment for Retinal Vein Occlusion
In retinal vein occlusion, predictive factors for visual outcome after ranibizumab treatment have not been evaluated comprehensively.
- Trial name
- NCT01968616
- Testing
- Ranibizumab, 0.5mg, Intravitreal
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Kyoto University, Graduate School of Medicine
Pediatric Cataract, Congenital Cataract
Shanghai Pediatric Cataract Study
The purpose of this study is to evaluate the long-term visual outcome of the cataract surgery using a large-scale and comprehensive database of pediatric cataract participants, including congenital and traumatic cataract.
- Conditions
- Pediatric Cataract, Congenital Cataract, Traumatic Cataract, Visual Outcome
- Trial name
- NCT03063216
- Testing
- intraocular lens implantation
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Evidence Based Cataract Study Group
Premature Birth
Early Intervention in Preterm Infants: Short and Long Term Developmental Outcome After a Parental Training Program
Preterm infants, during their stay in the Neonatal Intensive Care Unit (NICU), face a period of stressful environment, which may negatively impact early brain development and subsequent neurobehavioral outcomes.
- Trial name
- NCT02983513
- Testing
- Early Intervention
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Cataract, Presbyopia Correction
The Purpose is to Evaluate Visual Acuity for Distance, Intermediate and Near and Additionally Contrast Sensitivity at 25% and 10% of Illumination After Implantation of Trifocal IOL, Extended Range of Vision IOL, Bifocal IOL With Low Addition and Monofocal IOL
The objective of this study was to evaluate the effect of intraocular lens (IOL) selection on visual acuity and refractive outcomes, to assess the impact of IOL type on postoperative contrast sensitivity, and to investigate…
- Conditions
- Cataract, Presbyopia Correction, Visual Acuity
- Trial name
- IOL (NCT07008768)
- Testing
- Cataract surgery and refractive lens exchange surgery, TRIFOCAL IOL, EROV IOL
- Where
- Croatia
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- University Eye Hospital Svjetlost
Pain, Acute Postoperative
Comparison Of Outcome Of Wound Closure After Thyroid Surgery With And Without Platysma Suturing
Comparison Of Outcome Of Wound Closure After Thyroid Surgery With And Without Platysma Suturing in terms of wound scar and pain.
- Trial name
- NCT06485011
- Testing
- Paltysma suturing, Without Platysma suturing
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Children Hospital and Institute of Child Health, Lahore
Breast Cancer
Improvement of the Operative Outcome in Patients With Primary VEGF + Unifocal Breast Cancer or DCIS Through the Intraoperative Visualization of the Tumor Using Molecular Imaging and Bevacizumab-IRDye-800CW
It is a prospective, open, non-randomized, multicenter, one-armed, blinded (surgeon), diagnostic clinical trial according to AMG and MPG.
- Trial name
- DoT-FMI (NCT05359874)
- Testing
- Bevacizumab-IRDye800CW
- Sponsor
- Technical University of Munich
Diabetic Macular Edema
Pain and Visual Outcome in Intravitreal Bevacizumab Injection
In this double blind clinical trial, 1000 patients suffering from diabetic macular edema, age-related macular degeneration, neovascularization due to proliferative diabetic retinopathy and cystoid macular edema secondary to…
- Trial name
- pain & visual (NCT02790775)
- Testing
- Anti-VEGF in quadrant 1, Anti-VEGF in quadrant 2, Anti-VEGF in quadrant 3
- Where
- Iran
- Volunteers
- 1,004 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Chiasmal; Lesion, Prechiasmal; Lesion
Intraoperative Continuous Flash Visual Evoked Potentials Monitoring During Endoscopic Skull Base Surgery
Skull base surgeries performed in areas involving the visual pathway are associated with varying levels of postoperative visual dysfunction.
- Trial name
- NCT04068220
- Testing
- intraoperative FVEPs monitoring
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Fahad AlKherayf
Suture Materials, Wound Healing
Patient-Reported Outcomes of Four Intraoral Suture Materials
When patients undergo minor oral surgery, dentists use various types of stitches (sutures) to help the gums heal. These stitches can be made of different materials, and some might feel more comfortable, cause less pain, or…
- Conditions
- Suture Materials, Wound Healing, Patient Comfort, Oral Health-Related Quality of Life
- Trial name
- NCT07569237
- Testing
- Silk Suture (Braided, Non-absorbable), Polyglactin 910 Suture (Braided, Absorbable), Polyamide Suture (Monofilament, Non-absorbable)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Jordan