Clinical trials: Visualization
Visual Acuity
Clinical Evaluation of Approved and Investigational Contact Lenses Using New UV Additive
Randomized, 8-visit dispensing study over 14 weeks to evaluate the safety and efficacy of an investigational contact lens with a new UV blocker compared to a marketed contact lens.
- Trial name
- NCT02982018
- Testing
- senofilcon A with new UV blocker, senofilcon A
- Where
- 6 sites in United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Retinal Vein Occlusion, Age Related Macular Degeneration
Efficacy and Safety of Lucentis® (Ranibizumab Intravitreal Injections) in Chilean Patients With Diabetic Macular Edema.
Ranibizumab is a humanized anti-vascular endothelial growth factor (VEGF) monoclonal antibody fragment approved in Chile by the Instituto de Salud Pública for the treatment of diabetic macular edema (DME), retinal vein occlusion…
- Trial name
- NCT02140411
- Testing
- Ranibizumab Intravitreal injections
- Where
- Chile
- Volunteers
- 21 people
- Sponsor
- Novartis Pharmaceuticals
Acute Noninfectious Posterior, Intermediate, or Pan Uveitis
Study of FTY720 in Patients With Uveitis
This study will assess the safety, tolerability, and efficacy of FTY720 in patients with acute, noninfectious intermediate, posterior and pan uveitis
- Trial name
- NCT01791192
- Testing
- FTY720, Oral Corticosteroid
- Sponsor
- Novartis Pharmaceuticals
Visual Acuity
Clinical Evaluation of Daily Disposable Etafilcon A Cosmetic Contact Lenses (2022)
This is a multi-site, 4-visit, brand-masked, bilateral, 2x2 cross-over dispensing study to evaluate visual acuity.
- Trial name
- NCT05480514
- Testing
- TEST LENS, CONTROL LENS
- Where
- 2 sites in Hong Kong
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Function
Visual Function After Bilateral Implantation of AcrySof® Toric
The objective of this study was to evaluate visual function of AcrySof Toric and AcrySof Natural Intraocular Lenses (IOLs) following implant for replacement of cataract.
- Trial name
- NCT00758550
- Testing
- AcrySof® Toric IOL, AcrySof Natural
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Alcon Research
Macula Thickening
Efficacy of Topical Ketorolac Versus Placebo for Improving Visual Outcomes Following Multifocal IOL Implantation
The purpose of this study was to evaluate the efficacy of ketorolac 0.4% on quality of vision and macula thickening in patients undergoing cataract surgery using the ReStor® multifocal IOL.
- Trial name
- NCT00433225
- Testing
- Prednisolone Acetate, Ketorolac 0.4%, Gatifloxacin 0.3%
- Where
- United States
- Sponsor
- Innovative Medical
Astigmatism
Evaluation of Orientation and Visual Acuity of Four Toric Soft Contact Lenses When Head is Tilted at 90 Degrees
The purpose of this study is to determine the relative performance of a new toric soft contact lens against three toric contact lens currently available in market, specifically with orientation and visual acuity when head is…
- Trial name
- NCT00583908
- Testing
- senofilcon A, balafilcon A toric, lotrafilcon B toric
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Relapsing Remitting Multiple Sclerosis, Optic Neuropathy
Nanocrystalline Gold to Treat Remyelination Failure in Chronic Optic Neuropathy In Multiple Sclerosis
The objective of this trial is to assess the efficacy and safety of CNM-Au8 as a remyelinating treatment for vision-impairing MS lesions in participants who have chronic vision impairment as a result of Relapsing-Remitting…
- Conditions
- Relapsing Remitting Multiple Sclerosis, Optic Neuropathy, Optic; Neuritis, With Demyelination
- Trial name
- VISIONARY-MS (NCT03536559)
- Testing
- CNM-Au8
- Where
- 7 sites in United States, Australia and 1 more
- Volunteers
- 73 people
- Sponsor
- Clene Nanomedicine
Visual Acuity
Evaluation of Senofilcon A With New UV-blocker on a Neophyte Population
This is a 5-visit, single-arm, open-label, dispensing study. Each subject will be bilaterally fit with the test article for approximately 4 weeks of reusable daily wear with lens replacement occurring 2-weeks after initial…
- Trial name
- NCT03742271
- Testing
- senofilcon A
- Where
- 11 sites in United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Evaluation of Approved and Investigational Contact Lenses
This study is a randomized, 5-visit, partial subject masked, 2x3 bilateral crossover, dispensing clinical trial. During the study, each test article will be worn in a daily wear modality for at least 6 hours per day and 5 days…
- Trial name
- NCT03228212
- Testing
- CONTROL, TEST
- Where
- 5 sites in United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Colonic Diseases, Bowel Diseases
Evaluation of PillCam™ Colon 2 in Visualization of the Colon
To evaluate the performance of PillCam COLON 2 in regards to detection of patients with polyps where colonoscopy is considered as the gold standard reference.
- Trial name
- NCT01087528
- Testing
- PillCam™ (Capsule Endoscopy) Colon 2 capsule
- Where
- 4 sites in United States
- Volunteers
- 51 people
- Sponsor
- Medtronic - MITG
Human Papillomavirus (HPV), Cervical Intraepithelial Neoplasia
Validation of a Lab-free Low-cost Screening Test for Prevention of Cervical Cancer
The purpose of this study is to validate Automated Visual Evaluation (AVE), specifically the CINFinder version developed by DL Analytics, a point-of-care screening and triage diagnostic tool for cervical cancer based on the…
- Conditions
- Human Papillomavirus (HPV), Cervical Intraepithelial Neoplasia, Uterine Cervical Neoplasms, Cervical Cancers
- Trial name
- OPTICS (NCT06815939)
- Testing
- HPV Test, EVA System, Visual Inspection with Acetic Acid (VIA)
- Where
- El Salvador
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- DL Analytics
Dry Eye Syndromes, Dry Eye
Comparative Study of Rohto Dry-Aid® and Systane® Ultra in Patients With Dry Eye
The objective of this study is to evaluate the efficacy of Rohto Dry-Aid® in comparison to Systane® Ultra on visual function and tear film stability in patients diagnosed with Dry Eye.
- Trial name
- NCT03183089
- Testing
- Rohto Dry-Aid®, Systane® Ultra
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The Mentholatum Company
Onychomycosis of Toenails
Evaluation of the Performance of a Fungal Nail Treatment on the Visual Signs of Onychomycosis
This is a prospective, open label, non-comparative clinical investigation to evaluate the performance of a Fungal Nail Treatment on the visual signs of onychomycosis.
- Trial name
- NCT02546258
- Testing
- A Fungal Nail Treatment
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Visual Acuity, Astigmatism
LFR-260 vs Traditional Phoropter in Visual Acuity Testing
The purpose of this study is to establish if LFR-260 (investigational device) is not inferior in effectiveness to a traditional phoropter (control device) when applied in visual acuity test in subjects undergoing a full routine…
- Conditions
- Visual Acuity, Astigmatism, Anisometropia
- Trial name
- NCT05259163
- Testing
- LFR-260 portable phoropter, Traditional phoropter (SOC)
- Where
- 2 sites in United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Evolution Optiks Limited
Leber Hereditary Optic Disease
Efficacy and Safety Study of Bilateral IVT Injection of GS010 at Two Dose Levels in LHON Patients
The goal of this Clinical trial is to assess the safety and efficacy of GS010 at two dose levels on visual acuity and retinal mitochondrial activity in patients affected with ND4 Leber Hereditary Optic Neuropathy (LHON)
- Trial name
- REVISE (NCT07303296)
- Testing
- GS010 High dose, GS010 Low dose
- Where
- France
- Volunteers
- 14 people
- Sponsor
- GenSight Biologics
Cataract, Presbyopia
Comparative Analysis of the Visual Performance and Patient Satisfaction After Cataract Surgery With Implantation of a Medicontur Monofocal (877PAY) or a Medicontur Extended Depth of Focus (877PEY) IOL
The purpose of this multi-center, prospective, randomized, comparative clinical investigation was to evaluate and compare the visual performance at far, intermediate and near distances, the presence of photopic phenomena and…
- Conditions
- Cataract, Presbyopia, Ametropia
- Trial name
- NCT06642779
- Testing
- VFQ- 25 (Visual Function Questionnaire), Optical Biometry, Slit lamps / Fundoscopy / Biomicroscopy
- Where
- 3 sites in Hungary
- Volunteers
- 64 people
- Sponsor
- Medicontur Medical Engineering Ltd
Cataract, Dry Eye
Efficacy of Topical Cyclosporine Versus Tears for Improving Visual Outcomes Following Multifocal IOL Implantation
The purpose of this study is to evaluate the efficacy on quality of vision and dry eye signs and symptoms in patients undergoing cataract surgery using the ReZoom® multifocal IOL.
- Trial name
- NCT00349583
- Testing
- Topical Cyclosporine, Tears
- Where
- United States
- Sponsor
- Innovative Medical
Narrow Angle Patients at Risk for Angle Closure Glaucoma
Dysphotopsia Following Laser Peripheral Iridotomy
To establish the correlation of the location of the Nd:YAG laser peripheral iridotomy to the post operative visual symptoms experienced by some patients.
- Trial name
- NCT01758237
- Testing
- Neodymium-doped: Yttrium Aluminum Garnet (Nd:YAG) laser, Nd:YAG Laser Peripheral Iridotomy
- Where
- Canada
- Volunteers
- 214 people
- Sponsor
- Credit Valley EyeCare
Pathological Myopic Choroidal Neovascularization
601 Versus Ranibizumab in Patients With Pathological Myopic Choroidal Neovascularization (pmCNV)
To evaluate the safety and efficacy of intravitreal recombinant humanized anti-VEGF monoclonal antibody in patients with visual impairment due to pmCNV
- Trial name
- NCT04922151
- Testing
- 601, Ranibizumab
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.