Clinical trials: Weakness, Muscle
Weakness, Muscle
Effects of INDUS810 on Body Composition, Muscular Performance, and Training Adaptations
The purpose of this 12-week, interventional study is to determine the effects of oral supplementation with Indus810 (dietary supplement with active ingredient Fenugreek) on body composition, muscular performance, and training…
- Trial name
- NCT03850106
- Testing
- Indus810
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- The Center for Applied Health Sciences, LLC
Muscle Strength, Muscle Weakness
Reliability and Validation of New Manual Dynamometer to Measure Lower Limb Strength
INTRODUCTION: There are several ways to assess muscle strength: not only subjective ways, but also high standard equipment, such as isokinetic dynamometers. These, however, are expensive, and require extensive training.
- Trial name
- NCT05573139
- Testing
- Assessment of muscle strength by manual dynamometry
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Unilateral Primary Osteoarthritis of Hip
Comparing the Clinical Effects of Posterior Approach Versus Lateral Approach in Osteoarthritis Patients With a THA
The aim of this study is to investigate the clinical outcome of the two different, but widely used, surgical approaches (Posterior approach and Lateral approach) of primary total hip arthroplasty in patients diagnosed with…
- Trial name
- COMPALA (NCT01616667)
- Testing
- Total hip arthroplasty
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Age-related Muscle Decline
CALM-AF-AI: Counteracting Age-related Loss of Muscle With AAV-Follistatin Combined With Angiogenesis-Inducing VEGF Plasmid Gene Therapy
This Phase 1/2a, open-label, non-randomized study is designed to evaluate the safety and tolerability of intramuscular AAV9-Follistatin gene therapy administered either as monotherapy or in combination with a VEGF-encoding…
- Trial name
- CALM-AF-AI (NCT07443826)
- Testing
- AAV9-Follistatin gene therapy, VEGF Plasmid
- Where
- Honduras
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Unlimited Biotechnology LLC
Neurologic Diseases, Hemiparesis
NuroSleeve Powered Brace & Stimulation System to Restore Arm Function
The purpose of this study is to investigate if a person with weakness or paralysis in one or both arms, can use the NuroSleeve combined powered arm brace (orthosis) and muscle stimulation system to help restore movement in one…
- Conditions
- Neurologic Diseases, Hemiparesis, Quadriplegia, Muscular Dystrophies
- Trial name
- NCT04798378
- Testing
- Neurosleeve
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Poor Performance Status, Muscle Weakness
Innovative Training Program for Elderly in Need of Care Individuals
The goal of this randomized controlled study was to examine the effects of a 8 weeks innovative training regime (stochastic resonance whole-body vibration [SR-WBV] and virtual virtual games [VG]) in the skilling up phase on…
- Trial name
- NCT02102919
- Testing
- SR-WBV, Virtual Games (VG), Aktiv Tramp (Swiss Frei AG, Switzerland)
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bern University of Applied Sciences
Muscle Tightness, Muscle Weakness
Stretching Techniques of Knee Muscles and Their Effect on Joint Range, Suppleness and Muscle Activity in Elderly
The goal of this clinical trial was to compare the effect of two different types of stretching techniques in elderly population. The main questions it aims to answer are: 1.
- Trial name
- NCT05785416
- Testing
- Proprioceptive Neuromuscular Stretching - Contract Relax stretching (PNF-CR), Static Stretching (SS)
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Deepak Malhotra
Surgical Smoke Exposure, Occupational Exposure to Surgical Smoke
THE EFFECT OF SURGICAL MASK AND N95 MASK USE ON SURGICAL SMOKE IN OPERATING ROOM NURSES
This study was conducted to compare the effect of surgical mask and N95 mask use on physical symptoms due to surgical smoke in operating theatre nurses.
- Conditions
- Surgical Smoke Exposure, Occupational Exposure to Surgical Smoke, Headache, Dizziness
- Trial name
- NCT07404956
- Testing
- Surgical Mask, N95 Mask
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Stroke
Internally Versus Externally Guided Body Weight-Supported Treadmill Training (BWSTT) for Locomotor Recovery Post-stroke
The overriding goal of this proposal is to identify the critical physiological and biomechanical effects of BWSTT for promoting improved locomotor function in persons with post-stroke hemiparesis.
- Trial name
- NCT00125619
- Testing
- Locomotor training
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Postural Kyphosis, Neck Pain
Comparison Between Effect of Posterior Cervical Weighting and Deep Cervical Flexion Exercise on Forward Head Posture
It has been reported that the head protrudes forward relative to the body from the sagittal plane associated with the anterior shifting of the line of gravity (LOG) relative to the base of support (BOS).
- Conditions
- Postural Kyphosis, Neck Pain, Deformity of Spine, Deformity
- Trial name
- FHP (NCT04796051)
- Testing
- Neck orthosis - with posterior cervical weight, Deep cervical flexors exercise
- Where
- Egypt
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Muscle Weakness
Functional Change With MMS
Evaluate the safety and efficacy of magnetic muscle stimulation (MMS) of abdominal muscle.
- Trial name
- FMS (NCT04506502)
- Testing
- The ZELTIQ System
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Chronic Kidney Disease, Renal Insufficiency, Chronic
Reliability of Muscle Strength and Activation Assessment Tools and Effects of an Online Therapeutic Exercise Program in Patients With Chronic Kidney Disease
This research aims to evaluate the reliability and reproducibility of muscle strength and activation measurement tools, including isokinetic dynamometry and surface electromyography, in patients with chronic kidney disease (CKD).
- Conditions
- Chronic Kidney Disease, Renal Insufficiency, Chronic, Muscle Weakness, Sarcopenia
- Trial name
- NCT07292311
- Testing
- Reliability Assessment, Online Therapeutic Exercise
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Diabetes Mellitus, Type 2, Polyneuropathy Diabetes
Resistance Training in Patients With Diabetic Neuropathy
This is a population-based study of type 2 diabetes patients with and without neuropathy recruited from the Danish National Type 2 Diabetes cohort (DD2).
- Conditions
- Diabetes Mellitus, Type 2, Polyneuropathy Diabetes, Diabetes Complications, Diabetic Peripheral Neuropathy
- Trial name
- NCT03252132
- Testing
- 12-week resistance training
- Where
- Denmark
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Danish Pain Research Center
Sarcopenia, Covid19
Sarcopenia and Related Factors in Coronavirus Disease 2019 (COVID-19) Following Intensive Care
The primary aim of this study is to evaluate the patients who had pneumonia or severe acute respiratory distress syndrome (ARDS) due to COVID-19 in terms of sarcopenia and related factors following Intensive Care Unit (ICU).
- Conditions
- Sarcopenia, Covid19, Intensive Care Unit Acquired Weakness
- Trial name
- NCT05474157
- Testing
- Standard care treatment for COVID-19 in Intensive Care Unit
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Koç University
Neck Pain, Range of Motion
Comparative Effect of Neck Isometrics and Deep Cervical Flexion Exercises on Neck Pain Among Breastfeeding Females.
Neck pain is a common complaint among breastfeeding females, potentially attributed to sustained postures and muscle imbalance. Breastfeeding females experiencing neck pain, aged between 18-40 years, will be recruited through…
- Conditions
- Neck Pain, Range of Motion, Muscle Weakness, Breastfeeding
- Trial name
- NCT06877728
- Testing
- Neck isometric exercises: 3 times weekly for 6 consecutive weeks (18 sessions)
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Statin Intolerance
Effects of Epicatechin on Statins for Mitochondrial Dysfunction and Impaired Exercise Capacity
The purpose of this study is to gain insight into the side-effects of statin consumption, and assess the ability of epicatechin (a compound in dark chocolate) to counteract or reverse these changes.
- Trial name
- NCT02490527
- Testing
- Pure epicatechin capsules (50mg), Simvastatin (40mg)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Muscle Weakness
Delivra Topical Creatine for Improving Muscular Power
Creatine is a nutritional supplement that is often ingested to improve exercise performance. The advent of a new product that is applied to the skin overlying muscle offers potential benefit, if the creatine can be targeted to…
- Trial name
- NCT02960425
- Testing
- Delivra TM Livsport preworkout cream
- Where
- 3 sites in Canada
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Muscle Weakness, Dynapenia
Mirror Neurons in Older Participants
A critical problem facing aging adults is muscle weakness. Whereas scientists have traditionally attributed the loss of muscle strength with aging to muscle atrophy, emerging evidence suggests that impairments in the…
- Conditions
- Muscle Weakness, Dynapenia, Sarcopenia
- Trial name
- MNOP (NCT03946709)
- Testing
- Action Observation
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Muscular Atrophy, Muscle Weakness
Combined Effects of Nutritional and Exercise Countermeasures
The purpose of this study is to see if a combination of resistance exercises and amino acid capsules can reduce muscle loss and maintain muscle function during bedrest.
- Trial name
- NCT00447044
- Testing
- Resistance Exercise, diet orange soda, essential amino acids
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Muscle Strength, Muscle Weakness
Performance Output With Haptics - Evaluating Athlete Response and Unrealized Potential
This minimal risk, randomized, double-blind, placebo controlled Institutional Review Board (IRB)-approved observational study with functional measurements, will evaluate athletic performance after use of a drug- free…
- Trial name
- POWER-UP (NCT06430879)
- Testing
- VICTORY PATCH
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- SuperPatch Limited LLC