Clinical trials: Weakness
Old Age; Debility
Older People Gait: Physiomechanics and Functionality
The aim of study is to investigate gait in active elderly people regarding the kinematic parameters of gait, indicators of physical fitness and quality of life.
- Trial name
- NCT04348539
- Testing
- Balance training
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Old Age; Debility
Fall Prevention Pathways
Falls are a leading cause of injury and loss of independence in older adults, with evidence supporting exercise-based interventions and remote monitoring as effective strategies for reducing fall risk.
- Trial name
- NCT07824141
- Testing
- The Fall Prevention Pathway (FPP)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Emory University
Old Age; Debility, Psychological Distress
Mindfulness-based Short Intervention for Seniors - Decentering Effects on Cognitive Functions and Psychological Distress
The present study examined the effect of a short Mindfulness-based intervention emphasizing a 'decentering' component on elderly seniors.
- Conditions
- Old Age; Debility, Psychological Distress, Cognitive Change
- Trial name
- NCT04165005
- Testing
- decentering, guided imagery
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ben-Gurion University of the Negev
Chronic Stroke, Weakness, Muscle
Use of Hand-held Dynamometry to Obtain Objective Measures of Lower Extremity Force Production With Chronic Stroke
This study wants to know if using handheld dynamometry (HHD) to test leg strength in persons who have had a stroke, will reduce mistakes and give therapists better information to use for therapy.
- Trial name
- NCT05941962
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Frail Elderly Syndrome
Protocols and Guidelines for the Use of Digital Twins in Frail Older People
The Proto-Aging study aims to define experimental protocols and guidelines to enable the development of musculoskeletal models (digital twins) of elderly people, with the ultimate goal to comprehensively characterize frail elders…
- Trial name
- Proto-Aging (NCT05854316)
- Testing
- Comprehensive Biomechanical assessment
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Oxidative Stress, Inflammation
Oxidative Stress and Nutritional Supplementation Intervention Study
A major means whereby oxidative stress promotes aging-related disease is by activating inflammatory pathways. Decreasing oxidative stress and inflammation should ameliorate many of the problems associated with aging, including…
- Conditions
- Oxidative Stress, Inflammation, Aging, Dementia
- Trial name
- Oxi-Stress (NCT01234506)
- Testing
- secoisolariciresinol diglucoside
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Age-related Strength Loss
High-Intensity Interval Training in a Community Gym
This study will deliver a 9 week high intensity interval training (HIIT) class using functional movements within a community based gym. The class will be twice a week.
- Trial name
- NCT06976060
- Testing
- High-Intensity Interval Training
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Creighton University
Symptomatic Cervical Disc Disease
2-level Cervical Disc Replacement Comparing Prodisc C SK & Vivo to Mobi-C
A multi-center, prospective, randomized, controlled comparison of the prodisc C SK and prodisc C Vivo to the control, a similar, legally marketed total disc replacement device in subjects with symptomatic cervical disc disease…
- Trial name
- SMART (NCT04012996)
- Testing
- prodisc C SK and/or Vivo, Mobi-C Cervical Disc
- Where
- 30 sites in United States
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Centinel Spine
Electroacupuncture, Urinary Incontinence
Electroacupuncture Treatment for Urinary Incontinence (UI) in Women
The investigators have developed an investigation comparing electroacupuncture with pelvic floor exercises in female urinary incontinence (UI).
- Conditions
- Electroacupuncture, Urinary Incontinence, Women, Pelvic Floor Muscle Weakness
- Trial name
- ELECAPUN (NCT04842695)
- Testing
- electroacupuncture group
- Where
- Spain
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Dignity, Old Age; Debility
INNOVATEDIGNITY: Co-designing Digital Health Technologies With Older People in Homecare Settings.
One of the crucial components of successful ageing is to live independently in old age. Yet in UK alone, nearly 300000 older people require assistance with 3 or more essential daily tasks like eating, bathing and mobility which…
- Conditions
- Dignity, Old Age; Debility, Healthy Aging, Digital Technology
- Trial name
- NCT04884711
- Testing
- No Interventions. Participants will be using their everyday digital health technologies., In depth Interviews, Focus Group Discussions
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Brighton
Trigger Point, Muscle Weakness
Effects of Deep Trigger Point Dry Needling on Strength Measurements of the Gluteus Medius Musculature
The purpose of this study will be to assess the effect that the application of deep trigger point dry needling to latent trigger points has on strength measurements.
- Trial name
- NCT03580200
- Testing
- Trigger Point Dry Needling
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Emily Slaven, PT, PhD
Pelvic Floor Muscle Weakness
Comparison of Teaching Methods of Pelvic Floor Muscle Contraction in Women
The aim of our study; To evaluate the effectiveness of different teaching methods on correct pelvic floor muscle contraction in women who have not received pelvic floor muscle training (PFMT) before.
- Trial name
- NCT06306703
- Testing
- group1, group2, group 3
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Duygu Sultan Oge
Stroke, Ischemic, Stroke Hemorrhagic
Exploring Accessible Beauty for Individuals With Upper Extremity Deficits
The purpose of this study is to investigate the accessibility of beauty products for individuals with upper extremity disabilities.
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Stroke (CVA) or TIA, Stroke, Acute
- Trial name
- NCT05945784
- Testing
- Use of Rare Beauty makeup products
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Muscle Weakness
Growth Differentiation Factor 15 in ICU Acquired Muscle Weakness
Intensive care unit -acquired weakness (ICU- AW) is a common consequence linked to a worse outcome as evidenced by prolonged mechanical ventilation, longer ICU stays, greater mortality rates and a lower quality of life for…
- Trial name
- NCT06713746
- Testing
- growth differentiation factor 15
- Where
- Egypt
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Minia University
Osteoarthritis, Sarcopenia
The Strong Brain Study
To evaluate operational aspects of studying pre to post surgery/hospitalization changes in the integrity of a major white matter pathways and how these contribute to reductions in the ability to produce forceful muscle…
- Trial name
- NCT02320864
- Testing
- Total knee replacement surgery
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Florida
Childhood Cancer, Muscle Weakness
Imaging Skeletal Muscle Mitochondrial OXPHOS Activity In Acute Lymphoblastic Leukemia Survivors
The participants are being asked to take part in this trial, because the participant is a survivor of childhood cancer or agreed to be part of a volunteer group to understand the relation between cancer and cancer treatment and…
- Trial name
- NCT06819475
- Testing
- Magnetic Resonance Imaging, Magnetic Resonance Spectroscopy, Physical function assessment
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Ankle Disease, Muscle Weakness
Gluteal Musculature Activation to Improve Ankle Stability
The goal of this observational study is to to evaluate and correlate muscle activation in the gluteal musculature and ankle stability in a healthy population.
- Trial name
- TOBEMG (NCT06114654)
- Testing
- Physical Therapy
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Frailty Syndrome, Geriatric Health
Longitudinal Assessment of Lung Function and Respiratory Muscle Strength Following Training of the Inspiratory Muscles in Frail Older Adults (IMT-3)
This study aims to evaluate the effects of an 8-week inspiratory muscle training program on lung function and respiratory muscle strength in frail older adults aged 80 years and above.
- Conditions
- Frailty Syndrome, Geriatric Health, Respiratory Muscle Weakness, Age-Related Frailty
- Trial name
- NCT07556445
- Testing
- Inspiratory Muscle Training
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Francisco de Vitoria
Dementia, Weakness in the Exercise of the Family Caregiver Role of Older Adults With Dementia
Conectando Corazones Intervention in Family Caregivers of an Older Adult With Dementia
The objective of this randomized clinical trial, with pre-test and post-test measurements in an experimental group and a comparison group, was to evaluate the effect of the systematized nursing intervention "Conectando Corazones"…
- Trial name
- CONNECTING-FC (NCT07695194)
- Testing
- Conectando corazones, Conventional intervention
- Where
- Colombia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad de la Sabana
Weakness, Muscle, Muscle Weakness
Short Term Immobilization of the Lower Limb
The purpose of this study is to determine the effects of one week of knee-joint immobilization on muscle size, strength, neuromuscular function, and brain function.
- Conditions
- Weakness, Muscle, Muscle Weakness, Muscle Loss, Muscle Atrophy
- Trial name
- STILL (NCT05072652)
- Testing
- Neuromuscular Electrical Stimulation, Action Observation + Mental Imagery
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Central Florida