Clinical trials: Weight Loss, completed
Obesity
Weight Loss With Exenatide Treatment
The investigators are conducting a study that will investigate the possible mechanisms of weight loss associated with exenatide treatment and the metabolic characteristics of high responders (i.e.
- Trial name
- NCT01590433
- Testing
- Exenatide, Dietary counseling
- Where
- United States
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Jody Dushay
Thyroid, Obesity
Thyroid in Bariatric Surgery
This study is expected to provide novel data regarding potential structural and functional changes of the thyroid gland in morbidly obese adults following significant weight loss through bariatric surgery.
- Conditions
- Thyroid, Obesity, Insulin Resistance, Autoimmune Thyroiditis
- Trial name
- ThyrBar (NCT03048708)
- Testing
- Bariatric surgery
- Volunteers
- 10 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Obesity
Weight Loss Maintenance of a New Bioactive Compound (Metobes-Long)
The objective of the present study was to investigate the acute and sub-chronic effect of a supplement containing green tea extract, capsaisin, caffeine, tyrosine and calcium or placebo taken t.i.d on thermogenesis, body fat…
- Trial name
- NCT00302276
- Testing
- Metobes-compound
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Breast Cancer, Prostate Cancer
Survivorship Promotion In Reducing IGF-1 Trial
This is a prospective, single-center randomized trial with three arms, and an allocation ratio of 1:1:1. The study design is an efficacy study to evaluate the effect of metformin and coach-directed behavioral weight loss versus…
- Conditions
- Breast Cancer, Prostate Cancer, Lung Cancer, Colon Cancer
- Trial name
- SPIRIT (NCT02431676)
- Testing
- Metformin, Coach Directed Behavioral Weight Loss, Self-control weight loss
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Obesity, Overweight
Use of Facebook as a Motivating Factor in a Weight-reduction Program for Obese and Overweight Adolescents
The purpose of this study is to determine if Facebook can be used as a motivating factor for obese or overweight adolescents in a weight-reduction program.
- Trial name
- NCT01819376
- Testing
- Facebook Status Update
- Where
- Mexico
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- TecSalud Investigación Clínica
Overweight and Obesity
Effects of Inhibitory Control Training in Eating Behaviors
Overweight and obese individuals will be randomly assigned to a food-specific or generic inhibitory control training. Food intake, weight, and neural indices of inhibitory control will be assessed prior, immediately after the…
- Trial name
- N2ICT (NCT03599115)
- Testing
- Inhibitory Control Training
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Brigham Young University
Obesity
Effect of Low-calorie Diet and Orange Juice on Body Weight and Metabolic Parameters of Obese Subjects
This study aimed to verify if combination of a low calorie diet and orange juice consumption results in weight loss and ameliorates metabolic obesity-related biomarkers.
- Trial name
- LCD-OJ-OBESE (NCT02914249)
- Testing
- Orange juice (500 mL/d)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- São Paulo State University
Protein Metabolism
Optimal Protein Dose Per Meal During Weight Loss in Perspective to Maintaining Muscle Mass
The primary aim of the trial is to determine the optimal dose of protein per meal in relation to enhancing muscle protein synthesis and thereby in perspective counteract muscle loss during weight loss.
- Trial name
- NCT03326284
- Testing
- 15 g protein hypocaloric, 35 g protein hypocaloric, 60 g protein hypocaloric
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Bariatric Surgery
Gaining Optimism After Weight Loss Surgery (GOALS) II
This randomized controlled trial examines the feasibility, acceptability, and preliminary impact of an adapted positive psychology-motivational interviewing (PP-MI) intervention for physical activity among patients who have…
- Trial name
- GOALS (NCT04868032)
- Testing
- Positive Psychology-Motivational Interviewing, Physical Activity Education Control
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Massachusetts General Hospital
Neoplasm Metastasis, Bone Neoplasms
The Palliative Radiotherapy And Inflammation Study - PRAIS
Radiation therapy (RT) is one of the primary treatments for bone cancer pain due to metastatic cancer disease. About 6 of 10 patients obtain pain relief from RT.
- Trial name
- PRAIS (NCT02107664)
- Testing
- Palliative RT for bone cancer pain
- Where
- 3 sites in Norway
- Volunteers
- 580 people
- Sponsor
- Norwegian University of Science and Technology
Pediatric Obesity
Fixed Diet Plan and Calorie Counting Diet in Adolescents
Obesity is a chronic illness and multifactorial etiology, related to genetic factors, environmental and behavioral. Features association with several metabolic abnormalities in childhood, leading to increased risk of…
- Trial name
- NCT02741908
- Testing
- Calorie counting diet, Fixed diet plan
- Volunteers
- 66 people
- Sponsor
- MARCIO CORRÊA MANCINI
Overweight and Obesity
Neuronal and Behavioral Effects of an Implicit Priming Approach to Improve Eating Behaviors in Obesity
The purpose of this study is to determine how different behavioral interventions designed to alter food perceptions and behaviors affect brain responses to food, eating behaviors, and body weight.
- Trial name
- NCT05107908
- Testing
- Active Implicit Priming, Control Implicit Priming, Food Exposure Task
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Obesity, Gliosis, Weight-Loss
A Cohort Study of Weight Loss and Gliosis
Patients and clinicians need better options to prevent the weight regain that almost universally follows a weight loss intervention. In lay terms, a new, higher "set point" seems to occur after people gain weight.
- Trial name
- NCT03578887
- Testing
- Behavioral Weight Loss Program, Roux-en-Y Gastric Bypass or Sleeve Gastrectomy
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Washington
Nephrolithiasis, Uric Acid
Pathogenesis of Uric Acid Nephrolithiasis: Role of Pioglitazone/Weight Loss
The investigators will randomize overweight and obese iuan patients to Pio (45 mg/day, highest approved dose or placebo), WL (10% of body weight, following the established program used in the Diabetes Prevention Program), or…
- Trial name
- NCT04370093
- Testing
- Pioglitazone 45 mg, Weight Loss, Pioglitazone + Weight Loss
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Texas Southwestern Medical Center
Obesity, Insulin Resistance
Intervention Study With Omega-3 Fatty Acids for Weight Loss and Insulin Resistance in Adolescents
The purpose of this study is to evaluate if a supplement containing omega-3 long chain polyunsaturated fatty acids for three months reduce obesity and insulin resistance to obese adolescents if administered together with a…
- Trial name
- O3WLIRADOL (NCT01456221)
- Testing
- Omega3 and an hypocaloric diet., Sunflower oil with an hypocaloric diet.
- Where
- Mexico
- Volunteers
- 366 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Ketogenic Diet, Weight Loss
Impact of Exogenous Ketones on Indices of Keto-Adaptation in Obese Subjects on Weight Reducing Diets.
This project will be a three-group controlled 6-wk feeding study where all meals are prepared and provided to obese participants. All participants will be fed a 25% energy-restricted diet.
- Trial name
- STAK (NCT06449287)
- Testing
- Diet, Blood Draw, Ketone/Glucose Monitoring
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Obesity, Weight Loss
Evaluation of Safety, Efficacy and Thermogenesis-induction of RZL-012 in Overweight and Obese Volunteers
Obesity is a direct result of food-intake in excess of body energy expenditure. Thus, induction of increased energy expenditure via the activation of thermogenesis at targeted anatomical sites can counterbalance obesity.
- Conditions
- Obesity, Weight Loss, Overweight and Obesity
- Trial name
- NCT03171415
- Testing
- RZL-012
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Raziel Therapeutics Ltd.
Obesity, Overweight
Pilot Trial of "My Meal Mate" (MMM), a Smartphone Application for Weight Loss
The aim of this study is to implement an exploratory pilot trial of "My Meal Mate" (MMM), a smartphone application developed to facilitate weight loss, assessing its feasibility and acceptability.
- Trial name
- NCT01744535
- Testing
- "My Meal Mate" (smartphone application), Paper food diary, Online food diary
- Where
- United Kingdom
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Obesity or Overweight
A Research Study to See How Well CagriSema Helps People in East Asia With Excess Body Weight Lose Weight
This study will look at how well the new medicine CagriSema helps people with excess body weight lose weight compared to another medicine, semaglutide. The participants will receive one injection once a week.
- Trial name
- NCT05813925
- Testing
- Cagrilintide, Semaglutide
- Where
- 28 sites in Japan, Taiwan
- Volunteers
- 331 people
- Sponsor
- Novo Nordisk A/S
Obesity, Surgery
Omics Profiling of Weight Loss With Bariatric Surgery
Understanding how foods and nutrients are digested, absorbed and metabolized when weight is stable and during weight loss induced by bariatric surgery procedure using the technologies of genomics, transcriptomics, proteomics…
- Trial name
- Bariatric (NCT02757638)
- Testing
- Stable isotope infusion
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
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