Clinical trials: Whole Body Imaging
Obesity, NAFLD
Low-Calorie Diet in People With Prediabetes/Metabolic Syndrome
Significant weight reduction, achieved by low-calorie diet (LCD), will mobilise ectopic fat (visceral and particularly liver fat), improving insulin sensitivity and other metabolic syndrome components, with secondary beneficial…
- Conditions
- Obesity, NAFLD, Fatty Liver, Pre Diabetes
- Trial name
- CALIBRATE (NCT04786418)
- Testing
- Standard of care, Low-calorie diet
- Where
- United Kingdom
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Multiple Sclerosis
Entire-body PET Scans for Multiple Sclerosis
To evaluate whether an entire-body positron emission tomography (PET) scanner can be exploited to improve evaluation, monitoring and measurement of both peripheral and central demyelination in multiple sclerosis (MS) patients.
- Trial name
- EPSMS (NCT04390009)
- Testing
- Entire-body PET-CT scans, Amyvid radiopharmaceutical
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brain Health Alliance
Cancer, Metabolic Disease
An Observational Study On TheAccuracy Of Whole-Body Magnetic Resonance Imaging (Wb-Mri) ScreeningTo Predict Clinically Significant Diagnoses In General Population Subjects Interested In Proactive And Advanced General Preventive Healthcare.
This is a prospective, single-arm, observational study capturing data from whole-body magnetic resonance imagining (WB-MRI) from up to 100,000 male and female subjects 18 years of age or older recruited at multiple clinical sites…
- Conditions
- Cancer, Metabolic Disease, Aneurysm, Neurologic Disorder
- Trial name
- Hercules (NCT06212479)
- Testing
- MRI Scan
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Hercules
Stroke
A Mobile Brain/Body Imaging Platform for the Assessment and Optimization of Post-stroke Overground Robotic Gait Treatments
The study aims to identify neural biomarkers that can be used to monitor the recovery of locomotion and movement of post-stroke patients, both in natural settings and with enriched treatment using robotic device.
- Trial name
- COBI (NCT07510633)
- Testing
- overground wearable robotic device
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dr. Franco Molteni
Attention
Evaluating Multivariate MRI Maps of Body Awareness
Meditation skills, or paying attention to internal mental states, are thought to improve people's health. This study is developing a new brain measure of meditation skills, called the EMBODY Task, using functional magnetic…
- Trial name
- EMBODY (NCT03344081)
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Diabetes Mellitus, Type 2, PreDiabetes
18F-FDOPA PET/CT Imaging in Patients Undergoing Metabolic Surgery
The aim of the study is to compare the endocrine function of pancreas between pre and post metabolic surgery in patients with type 2 diabetes or prediabetes.
- Conditions
- Diabetes Mellitus, Type 2, PreDiabetes, Obesity
- Trial name
- NCT03821961
- Testing
- Metabolic Surgery
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Obesity
Ultrasound Imaging For Facilitating Labour Epidurals in Obese Parturients
The efficacy of an epidural depends mainly on accurate placement of the catheter in the epidural space. Therefore, identification of the epidural space is the most vital part of the procedure.
- Trial name
- NCT00439998
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Structure and Function of MRI
Ultrahigh Field Body MR Imaging
The primary objective of this study is to develop new ways to acquire MRI data and/or new ways to analyze the acquired data.
- Trial name
- NCT02236143
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Major Depressive Disorder (MDD), Schizophenia Disorder
Prospective Observational Study of the Relationship Between Sociodemographic Factors, Blood-based Biomarkers and Psychiatric Symptoms in Neurodegenerative Diseases and Mental Disorders
This is a prospective observational study to identify sociodemographic factors that predict mental health outcomes in the European population and provide evidence linking common, modifiable sociodemographic risk factors for…
- Conditions
- Major Depressive Disorder (MDD), Schizophenia Disorder, Bipolar 1 Disorder, Alzheimer Disease
- Trial name
- Synapsing-SD (NCT07239843)
- Where
- Spain
- Volunteers
- 1,310 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Overweight and Obesity
Neuronal and Behavioral Effects of an Implicit Priming Approach to Improve Eating Behaviors in Obesity
The purpose of this study is to determine how different behavioral interventions designed to alter food perceptions and behaviors affect brain responses to food, eating behaviors, and body weight.
- Trial name
- NCT05107908
- Testing
- Active Implicit Priming, Control Implicit Priming, Food Exposure Task
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Whole Body Imaging, Prostate
AI Technologies for Enhanced and Celerated High-Field WB-MRI
Single-center, cross-sectional observational study assessing the feasibility of advanced accelerated MRI sequences versus standard ones in terms of image quality, diagnostic reliability, and acquisition time.
- Conditions
- Whole Body Imaging, Prostate, MRI, Lung
- Trial name
- AITECH-MRI (NCT07678320)
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Metabolic Diseases
Magnetic Resonance Imaging in Metabolic Diseases
This study aims to leverage structural, functional, and metabolic magnetic resonance imaging (MRI) of the brain to identify imaging features that correlate with clinical parameters.
- Trial name
- NCT06709846
- Where
- Germany
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Bariatric Surgery Candidate
Change in Reward System Activation and Gut Microbiota Following RYGB and Sleeve Gastrectomy for Weight Loss vs. Control-Heads Up Ancillary
Bariatric surgery is considered an effective long-term intervention for the treatment of obesity and associated complications. While bariatric surgery has been shown to result in a large sustained weight loss, the degree of…
- Trial name
- NCT02735564
- Testing
- Bariatric Surgery
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Lung Cancer, Nonsmall Cell
[18F]F-AraG/Total Body PET Imaging and Healthy Subjects and Lung Cancer Patients
In this pilot study, healthy volunteers and patients with Non-Small Cell Lung Cancer will undergo [18F]F-AraG dynamic imaging on the uEXPLORER total body Positron Emission Tomography/Computerized Tomography scanner to obtain…
- Trial name
- NCT04678440
- Testing
- [18F]F-AraG Imaging
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Normal Body Weight, Obesity
Endocrine and Neural Control of Eating in Women
The purpose of this study is to better understand how female sex hormones influence the food intake in the gut system through the release of satiety hormones as well as through central regulative mechanisms in the brain that…
- Trial name
- NCT02994420
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Overweight and Obesity, Cancer
Devaluing Foods to Change Eating Behavior
Excessive eating of energy-dense foods and obesity are risk factors for a range of cancers. There are programs to reduce intake of these foods and weight loss, but the effects of the programs rarely last.
- Trial name
- NCT03557710
- Testing
- Devaluing energy-dense foods for cancer-control
- Where
- United States
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- University of Oregon
PASC Post Acute Sequelae of COVID-19
Multiparametric [18F]F-AraG Imaging in Post-Acute Sequelae of COVID-19 (PASC)
This study uses total-body [¹⁸F]F-AraG PET/CT imaging to investigate immune activation and vascular changes in individuals with post-acute sequelae of SARS-CoV-2 infection (PASC), also known as Long COVID.
- Trial name
- NCT07076862
- Testing
- A.1 - [¹⁸F]F-AraG PET/CT (90-min dynamic + 4-h static), A.2 - [¹⁸F]F-AraG PET/CT (60-min dynamic only), B.1 - [¹⁸F]F-AraG PET/CT (90-min dynamic + 4-h static)
- Where
- 2 sites in United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Coronary Heart Disease, Stroke
Hamburg City Health Study - a German Cohort Study
The Hamburg City Health Study (HCHS) is a large, prospective, long-term, population-based cohort study and a unique research platform and network to obtain substantial knowledge about several risk and prognostic factors in major…
- Conditions
- Coronary Heart Disease, Stroke, Dementia, Cancer
- Trial name
- HCHS (NCT03934957)
- Where
- Germany
- Volunteers
- 45,000 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Obesity
MRI Based Study to Assess Brain-gut Axis in Obesity
The mechanism of neural communication between the brain and gut in the regulation of food intake is complex and not fully understood.
- Trial name
- BGImaging (NCT05437653)
- Testing
- Nutritional Drink A, Nutritional Drink B
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Visceral Obesity, Atherosclerosis
Abdominal Fat and Imaging Measurements of Heart Disease
Although it is frequently mentioned in the media that overweight and obesity have reached epidemic proportions worldwide and in this country, some Canadians are perplexed and sometimes confused about the role of obesity in…
- Conditions
- Visceral Obesity, Atherosclerosis, Metabolic Syndrome
- Trial name
- NCT01447745
- Where
- Canada
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- Laval University