Clinical trials: Wound; Knee
Knee Injuries
The Effectiveness of a Coach-Focused Intervention on Preventing Knee Injuries in Amateur Football Players
The goal of this clinical trial is to find out if a coach-focused intervention can help prevent sudden-onset, severe knee injuries in youth and senior amateur football players.
- Trial name
- NCT06846008
- Testing
- Ahead of the Game, Usual Practice
- Where
- Denmark
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Marius Henriksen
Meniscus Tear, Tibial, Osteoarthritis, Knee
Arthroscopic Partial Meniscectomy Versus Exercise Therapy for Meniscal Injuries in Older Patients, a 5 Year Follow up.
Arthroscopic partial meniscectomie (APM) offers little short-term to medium-term benefit above sham surgery or non-surgical management for knee function in most patients with a symptomatic degenerative meniscus tear.
- Trial name
- NCT05068843
- Testing
- arthroscopic partial meniscectomy, Physical therapy
- Volunteers
- 321 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Rupture of Anterior Cruciate Ligament, Infiltration
Local Infiltration Analgesia vs Adductor Canal Block for Analgesia After Anterior Cruciate Ligament Reconstruction
Early rehabilitation after anterior cruciate ligament reconstruction is of paramount importance and requires optimal pain control based on a multimodal concept, including injection of local anaesthetics.
- Conditions
- Rupture of Anterior Cruciate Ligament, Infiltration, Regional Anesthesia Morbidity
- Trial name
- NCT02524652
- Testing
- Ropivacaine 0.5% 20 mLs
- Where
- Switzerland
- Volunteers
- 104 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Total Knee Arthroplasty, Osteo Arthritis Knee
In Vivo Kinematics for Subjects Having a MicroPort Medial Pivot or DePuy Attune PCR TKA
In vivo knee kinematics will be assessed for 20 subjects that have been implanted with either a MicroPort Medial Pivot or DePuy Attune posterior cruciate retaining (PCR) total knee arthroplasty (TKA) by Dr.
- Conditions
- Total Knee Arthroplasty, Osteo Arthritis Knee, Knee Injuries, Knee Imlant
- Trial name
- TKA PCR (NCT04103502)
- Testing
- MicroPort Medial Pivot TKA, DePuy Attune PCR TKA
- Where
- 3 sites in United States
- Sponsor
- The University of Tennessee, Knoxville
Meniscus Injury, Knee Osteoarthritis
Knee Arthroscopy Cohort Southern Denmark (KACS)
PURPOSE: To investigate the natural time course of patient-reported outcomes after meniscus surgery and identify factors associated with good and bad outcome after surgery.
- Trial name
- KACS (NCT01871272)
- Testing
- Arthroscopic Meniscus Surgery
- Where
- 4 sites in Denmark
- Volunteers
- 491 people
- Sponsor
- University of Southern Denmark
Anterior Cruciate Ligament Injury
Effect of Tourniquet Use on the Pivot Shift Test
This prospective study will evaluate whether tourniquet inflation affects the results of the pivot shift test in patients undergoing anterior cruciate ligament (ACL) reconstruction.
- Trial name
- NCT07831941
- Testing
- Thigh Tourniquet Inflation
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Umraniye Education and Research Hospital
Sprain
Ketoprofen 10% Cream for Treatment of Pain Associated With Mild to Moderate Acute Soft Tissue Injury
Transdel Pharmaceuticals is investigating a topical cream formulation consisting of 10% ketoprofen for the local treatment of pain associated with mild to moderate acute soft tissue injury in this confirmatory Phase 3 trial.
- Trial name
- NCT01223053
- Testing
- Ketoprofen 10% cream
- Sponsor
- Imprimis Pharmaceuticals, Inc.
ACL Tear, ACL Sprain
Knee vs. Ankle Training on Knee Mechanics After ACLR
This study will be conducted to investigate if there is any difference between starting rehabilitation program after ACL reconstruction with knee joint training followed by ankle joint training and starting it with ankle joint…
- Conditions
- ACL Tear, ACL Sprain, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Injuries
- Trial name
- NCT05241795
- Testing
- Knee then Ankle rehabilitation protocol, Ankle then Knee rehabilitation protocol
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- October 6 University
Amputation, Traumatic, Phantom Sensation
Investigating The Effect of Phantom Sensation on Gait in Individuals With Unilateral Below-Knee Amputation
Amputation is a problem that can be encountered for many reasons, can cause functional disability in varying severities and puts a multifaceted financial burden on individuals, society, and states.
- Trial name
- NCT05177341
- Testing
- Determining Preferred Walking Speed
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Trakya University
Knee Injury, Knee Osteoarthritis
Monitoring Of Helsingborg Acute Knee Injuries (MOHAK)
Using magnetic resonance imaging (MRI), laboratory analyses and patient reported outcomes, the overall aim of this study is to investigate structural injuries and biochemical alterations in the acutely injured knee and to relate…
- Trial name
- NCT01382173
- Where
- Sweden
- Volunteers
- 192 people
- Sponsor
- Lund University
Football Players, Sport Injury
Neuromuscular and Proprioceptive Training in Football Players
The objective of this study was to determine the effect of proprioceptive and neuromuscular training on landing errors and balance of the football players.
- Conditions
- Football Players, Sport Injury, Sports Physical Therapy
- Trial name
- NCT04051554
- Testing
- Neuromuscular and Proprioceptive Training, Conventional Training
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
ACL Tear, ACL
Comparing Adductor Canal Block and Adductor Canal Block-Local Infiltration Analgesia for Post-operative Pain Management
Anterior cruciate ligament (ACL) reconstruction is one of the most commonly performed surgeries amongst young orthopedic surgery patients.
- Conditions
- ACL Tear, ACL, ACL Injury
- Trial name
- NCT04721119
- Testing
- Local Infiltration Anesthetic, Local Infiltration Anesthetic + Adductor Canal Block
- Volunteers
- 100 people
- Sponsor
- Ottawa Hospital Research Institute
ACL Tear
Comparison of Methods in Post Operative Knee Arthroscopy Rehabilitation
The aim of this study is to investigate the efficacy of blood flow restriction (BFR) therapy in post-operative rehabilitation following knee arthroscopy for primary ACL reconstruction.
- Trial name
- ACL BFR (NCT05735236)
- Testing
- BFR Cuff
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of Colorado, Denver
Isolated Cartilage Injury of the Knee
Sprifermin (AS902330) in Cartilage Injury Repair (CIR)
Several people all over the world suffer from cartilage injuries in the knee. Symptoms include pain, joint swelling, and loss of function. Without repair, cartilage injury may ultimately lead to osteoarthritis (OA).
- Trial name
- NCT01066871
- Testing
- Sprifermin (AS902330) 10 mcg, Sprifermin (AS902330) 30 mcg, Sprifermin (AS902330) 100 mcg
- Where
- Germany
- Volunteers
- 74 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Patellar (or Kneecap) Instability and Mal-alignment
CT Analysis of the Patellofemoral Joint in Patients Having Knee Surgery
The primary hypothesis is that measures of patellofemoral alignment obtained from the investigational cone beam CT scanner will be reduced, but still correlated to those obtained from the conventional CT scan.
- Trial name
- PF (NCT02257099)
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- State University of New York at Buffalo
Knee Injuries
Comparison Of Isometric And Isokinetic Strength Training Effects On Physical Performance In Athletes With Knee Pain
Frequent sports events causing more injuries in athletes causing decline in their performance. Injuries around knee joint are common. Strength training of hamstring and quadriceps are effective tool in rehabilitation.
- Trial name
- NCT03641781
- Testing
- isometric strength training and isokinetic strength training
- Volunteers
- 50 people
- Sponsor
- Isra University
Anterior Cruciate Ligament Injuries, Sport Injury
Better and Safer Return to Sport
A prospective cohort design will be used to assess differences in outcomes between pivoting sport athletes with anterior cruciate ligament reconstruction (ACLR) who follow usual care and those who follow a treatment algorithm…
- Trial name
- BEAST (NCT04049292)
- Testing
- Better and safer return to sport (BEAST), Usual care
- Where
- 2 sites in Norway
- Volunteers
- 250 people
- Sponsor
- Norwegian School of Sport Sciences
Anterior Cruciate Ligament Injuries
The Influence of Neuromuscular Training on Whole-body Movement Strategies and Knee Mechanics During Change-of-direction Tasks in Sports Science Students
Background Knee injuries are common during sports that require fast change-of-direction (COD) movements such as sidestepping and pivoting during soccer, basketball, handball, and related sports.
- Trial name
- NCT05014009
- Testing
- FIFA11+ and multidirectional training (MD), FIFA11+ and linear sprint training (MD)
- Where
- Austria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universitaet Innsbruck
Brain Injury
Biofeedback Gait Retraining for Stiff Knee Gait Correction
The research team has developed a visual kinematic biofeedback system which is designed to help children with hemiplegic cerebral palsy (CP) correct a pattern of reduced knee extension in terminal swing and early stance.
- Trial name
- NCT05105763
- Testing
- Sequential switched feedback training on the knee and the hip (Condition A), Feedback training on the knee alone (Condition B)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kessler Foundation
Patella Fracture, Aging
Patella Fracture : A Randomized Controlled Trial
This is a multi-centre, randomized controlled trial comparing operative and non operative treatment for displaced patella fractures in elderly, low-demand patients.
- Trial name
- NCT03445819
- Testing
- Group A: Surgical Treatment, Group B: Conservative Treatment
- Where
- 3 sites in Canada
- Volunteers
- 84 people
- Sponsor
- Unity Health Toronto
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