Clinical trials: Wound Healing Complication
Healing Wound, Alveolar; Wound
Ultrasound for Socket Healing Evaluation
The design is a single blinded, dual comparative study of ultrasound versus micro-CT/LASCA in one study group. Up to a total of 140 subjects registered will be recruited.
- Conditions
- Healing Wound, Alveolar; Wound, Alveolar Bone Loss, Image
- Trial name
- NCT06017193
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Wound Healing Disorder, Wounds and Injuries
Bone Bioactive Liquid Efficiency in Improving Dental Implant Osteointegration Oral Soft Tissue Hellingand Oral Surgery
The investigators implanted 264 Galaxy TS implants (with or without BBL) in 33 patients across both jaws. Implant stability and osseointegration were assessed using Initial Stability Quotient (ISQ) measurements, computed…
- Conditions
- Wound Healing Disorder, Wounds and Injuries, Wound Surgical
- Trial name
- BBLIS (NCT06371430)
- Testing
- Dental Implant insertion and tooth extraction
- Where
- Spain
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Biointelligent Technology Systems SL
Surgical Wound Healing, Scar Tissue
Reducing Wound Complications in Breast Surgery Using hACM
The purpose of this study is to evaluate whether intraoperative application of human amnion chorion membrane (hACM) improves wound healing and scar outcomes in breast surgery.
- Trial name
- NCT07881939
- Testing
- Dehydrated Human Amnion Chorion Membrane
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Tourniquets, Knee Arthroplasty, Total
Tourniquet Pressure in Primary Total Knee Arthroplasty
This proposed novel randomized control trial (RCT) seeks to address this gap in TKA protocol by gaining a better understanding of the relationship between tourniquet pressure and time, and intraoperative performance and…
- Conditions
- Tourniquets, Knee Arthroplasty, Total, Knee Replacement, Total
- Trial name
- NCT02830087
- Testing
- Tourniquet Cuff Pressure
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Osteoarthritis of Knee, Edema
Microcurrent Stimulation Reduces Post-Operative Swelling and Healing Time Following Knee Replacement Surgery
The purpose of this study is to determine if patients undergoing a total knee arthroplasty (TKA) experience a clinically significant reduction in healing time when treated post operatively with a specific form of micro and…
- Conditions
- Osteoarthritis of Knee, Edema, Wounds and Injuries
- Trial name
- NCT02623660
- Testing
- ODIN1, Standard Care, Diagnostic Device Testing
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bioelectric Research Corporation
Postoperative Pain, Recurrence
Desarda Repair Compared to Lichtenstein Repair for the Treatment of Inguinal Hernias
The Lichtenstein technique for hernia repair is safe and simple, but the underlying mesh prosthesis has its setbacks, as it acts as a mechanical barrier5.
- Conditions
- Postoperative Pain, Recurrence, Wound Complication
- Trial name
- NCT04850131
- Testing
- Desarda repair
- Where
- Pakistan
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Benazir Bhutto Hospital, Rawalpindi
Pain, Postoperative, Healing Wound
Evaluation of the Effects of Medicaments Used After Free Gingival Graft on Postoperative Complications.
In our study, three different medicaments were evaluated in terms of postoperative complications after free gingival grafting (FGG).
- Conditions
- Pain, Postoperative, Healing Wound, Hemorrhage, Analgesia
- Trial name
- NCT05386667
- Testing
- Majezik %0.25 oral spray, Aftamed oral spray, Crystalin oral spray
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Postoperative Pain, Postoperative Edema
Patient Satisfaction and Recovery Outcomes Associated With Perioperative ELIXIR MD Use
The goal of this observational registry study is to characterize postoperative recovery outcomes in adult patients receiving standard-of-care perioperative light therapy using an FDA-cleared photobiomodulation device as part of…
- Conditions
- Postoperative Pain, Postoperative Edema, Postoperative Ecchymosis, Surgical Wound Healing
- Trial name
- NCT07311889
- Testing
- Perioperative photobiomodulation light therapy
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Elixir MD Inc
Impacted Mandibular Third Molar, Wound Healing
Adjacent Molar Outcomes After Third Molar Surgery With PRF or Collagen Sponge
This study aims to compare platelet-rich fibrin (PRF) and an absorbable collagen sponge in extraction sockets following impacted mandibular third molar removal in terms of postoperative clinical healing and periodontal and…
- Conditions
- Impacted Mandibular Third Molar, Wound Healing, Postoperative Pain
- Trial name
- PRFvsCOLL-3M (NCT07530068)
- Testing
- Platelet-rich fibrin (PRF), Absorbable Collagen Sponge
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Gazi University
Diabetic Foot Ulcers
Non-Invasive Assessment of Wound Healing With Optical Methods
The objective of this project is to further the development of a non-invasive optically based NIR (Near Infrared) device to enable the quantitative diagnosis, monitoring and treatment optimization of chronic wounds (especially…
- Trial name
- NCT00578604
- Testing
- diffuse near infrared spectroscopy measurements
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Drexel University College of Medicine
Cesarean Section Complications, Wound Breakdown
Antimicrobial Dressing Versus Standard Dressing in Obese Women Undergoing Cesarean Delivery
This will be an open label pilot randomized controlled clinical trial. Women undergoing cesarean delivery will be randomized to have standard wound dressing care or chlorohexidine gluconate (CHG) impregnated wound dressing…
- Conditions
- Cesarean Section Complications, Wound Breakdown, Wound Infection, Satisfaction
- Trial name
- NCT03887299
- Testing
- ReliaTect™ Post-Op Dressing (contains chlorohexidine gluconate or CHG), Standard Wound Care
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Obesity, Morbid, Obesity
CiNPT for Abdominoplasties in Post-bariatric Patients Study
The overarching goal of this research is to assess whether the post-operative use of closed-incision Negative Pressure Therapy (ciNPT) accelerates healing of surgical wounds, improves surgical outcomes, and reduces the rate of…
- Conditions
- Obesity, Morbid, Obesity, Obesity, Abdominal, Wound
- Trial name
- CAPS (NCT04214236)
- Testing
- ciNPT group, Control group
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera, Ospedale Civile di Legnano
Pelvic Organ Prolapse, Surgery
Comparison of Two Apical Repair Methods in Women Undergoing Repairs for Prolapse
To date no study has determined prospectively which technique is superior to prevent recurrent Pelvic Organ Prolapse (POP) after vaginal hysterectomy- a major unmet clinical need.
- Conditions
- Pelvic Organ Prolapse, Surgery, Quality of Life, Complication
- Trial name
- NCT03113513
- Testing
- fixation of the vaginal apex
- Where
- Austria
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Wound Healing, Alveolitis of Jaw
Effect of Curcumin Topical Spray on Wound Healing After Tooth Extraction
This randomized, single-blind, controlled clinical trial aims to evaluate the effects of a topical curcumin spray on post-extraction wound healing and postoperative symptoms in adults undergoing first molar extraction.
- Conditions
- Wound Healing, Alveolitis of Jaw, Tooth Extraction, Curcumin
- Trial name
- NCT07874789
- Testing
- Curcumin Topical Spray, Chlorhexidine Topical Spray
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Impacted Third Molar, Postoperative Pain
Natural Enzyme Mouthwash After Third Molar Surgery
This clinical study investigates whether a natural enzyme-containing mouthwash (ORAL7®) can improve healing, pain and mouth opening after the surgical removal of impacted lower wisdom teeth (mandibular third molars), compared to…
- Conditions
- Impacted Third Molar, Postoperative Pain, Trismus, Wound Healing
- Trial name
- NCT07627945
- Testing
- ORAL7® Mouthwash, 0.2% Chlorhexidine Gluconate Mouthwash
- Where
- Malaysia
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- MBD MARKETING SDN. BHD.
Failed Back Surgery Syndrome
Low Level Laser Therapy to Reduce Comorbidity in Spinal Surgery
Each year, more than one million individuals worldwide are submitted to laminectomies, with a failure rate higher than 40%. Postlaminectomy epidural adhesion is implicated as a main cause of ''failed back surgery syndrome'' and…
- Trial name
- LASPINE (NCT02529657)
- Testing
- Low Level Laser Therapy
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Diabetes Mellitus, Diabetes Complications
Comparison of Resin Salve and Octenidine in Patients With Neuropathic Diabetic Foot Ulcers
Prevalence of diabetic foot ulcers are reported to be 15% in patients who suffer from diabetes and ulcerations are present in 84% of all diabetes-related amputations.
- Conditions
- Diabetes Mellitus, Diabetes Complications, Diabetic Neuropathies, Wound Infection
- Trial name
- NCT02169167
- Testing
- Resin salve treatment, Octenidine treatment
- Where
- Poland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Janne J. Jokinen
Wound Heal, Diabetic Foot Ulcer
Effect of Topical Ozone on The Healing Diabetic Foot Ulcer
Despite conflicting and contradictory evidence regarding its efficacy, some wound care centres have advocated and adopted ozone for treating DFU. However, there are gaps in the application of topical ozone therapy.
- Conditions
- Wound Heal, Diabetic Foot Ulcer, Ozone
- Trial name
- NCT05977309
- Testing
- Topical ozone therapy
- Where
- Indonesia
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Asmat Burhan
Inguinal Hernia, Surgery--Complications
Bassini Inguinal Hernia Repair: Obsolete Or Still A Viable Surgical Option?
Retrospective review of hernia surgery patients at HHMcGuire VAMC focusing on repair type and postoperative complications.
- Conditions
- Inguinal Hernia, Surgery--Complications, Surgical Complication
- Trial name
- NCT04888078
- Testing
- Bassini hernia repair
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Hunter Holmes Mcguire Veteran Affairs Medical Center
Pain, Postoperative
Platelet Rich Fibrin VS Hyaloronic Acid in Management of Pain After Harvesting a Free Gingival Graft
Comparative study to assess the efficacy of topical application of 0.2% hyaluronic acid vs platelet rich fibrin in decreasing a postoperative pain following free gingival graft procedure . .
- Trial name
- NCT03814707
- Testing
- Topical application of 0.2% hyaluronic acid gel, Platelet rich fibrin
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- mostafa soliman