Clinical trials: Wound Seroma
Breast Cancer, Seroma
Seroma Reduction and Drain Free Mastectomy
To prove that omitting drains after mastectomy and flap fixation does not contribute to higher incidence of seroma formation and therefore reducing patient disutility such as seroma aspirations and visits to the outpatient…
- Conditions
- Breast Cancer, Seroma, Wound Complication
- Trial name
- SARA (NCT04035590)
- Testing
- No drain, With drain
- Where
- Netherlands
- Volunteers
- 250 people
- Sponsor
- Zuyderland Medisch Centrum
Seroma
Fibrin Glue in Inguinal Lymphadenectomy
Seroma is one of the most common encountered morbidities after inguinal lymph node dissection (ILND). It can cause not only much nuisance to both patients and doctors but also its presence can lead to many complications.
- Trial name
- NCT04666051
- Testing
- Application of fibrin glue sealant
- Volunteers
- 32 people
- Sponsor
- Menoufia University
Obesity, Morbid, Obesity
CiNPT for Abdominoplasties in Post-bariatric Patients Study
The overarching goal of this research is to assess whether the post-operative use of closed-incision Negative Pressure Therapy (ciNPT) accelerates healing of surgical wounds, improves surgical outcomes, and reduces the rate of…
- Conditions
- Obesity, Morbid, Obesity, Obesity, Abdominal, Wound
- Trial name
- CAPS (NCT04214236)
- Testing
- ciNPT group, Control group
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera, Ospedale Civile di Legnano
Malignant Melanoma, Carcinoma, Squamous Cell
Post-Operative Drainage Following Lymph Node Dissection
The purpose of this study is to determine whether the use of fibrin sealant reduces post-operative drainage following groin and axillary lymph node dissection.
- Trial name
- NCT00324272
- Testing
- Fibrin Sealant (Tisseel) used in the Experimental Arm.
- Volunteers
- 74 people
- Sponsor
- Oxford University Hospitals NHS Trust
Surgical Site Infection, Wound Complication
VAC Dressings for Colorectal Resections
Surgical Site Infections (SSIs) and wound complications are common occurrences following colorectal resection surgery. Incisional Negative Pressure Wound Therapy (iNPWT) has developing evidence for improving wound complication…
- Conditions
- Surgical Site Infection, Wound Complication, Wound Dehiscence, Seroma
- Trial name
- VACCRR (NCT02967627)
- Testing
- Incisional Negative Pressure Wound Therapy (iNPWT), Sterile Gauze Dressing
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Surgical Wound Infection, Hematoma
Comparing Outcomes Of Single Layer Versus Multilayer Leg Closure Techniques Following Great Saphenous Vein Harvesting For CABG
This study aims to address the knowledge gap by comparing the outcomes of single-layer and multi-layer leg closure techniques following great saphenous vein harvesting for Coronary artery bypass grafting. Research question: 1.
- Conditions
- Surgical Wound Infection, Hematoma, Seroma Following Procedure, Prolonged Hospital Stay
- Trial name
- CABG (NCT07355452)
- Testing
- Multi-layer closure (MLC), singlelayer closure for leg wound
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- National Institute of Cardiovascular Diseases, Pakistan
Amputation, Amputation; Postoperative, Sequelae
Evaluation of Closed Incision Negative Pressure Dressing (PREVENA) to Prevent Lower Extremity Amputation Wound Complications
This study is a prospective, multi-center, two-arm, unblinded, and randomized controlled trial with a goal of evaluating the impact of a closed incision negative pressure dressing (PREVENA) on incidence of post-operative wound…
- Conditions
- Amputation, Amputation; Postoperative, Sequelae, Wound Dehiscence, Seroma
- Trial name
- PREVENA-AMP (NCT03773575)
- Testing
- PREVENA™ PEEL & PLACE™ Dressing Kit
- Where
- 3 sites in United States, Italy
- Volunteers
- 272 people
- Sponsor
- Thomas Jefferson University
Parotid Neoplasms, Post-operative Complications
Swedish National Parotidectomy Study (SNaPs): Drainless Versus Standard Surgery
The purpose of this study The purpose of this study is to find out if it is safe to perform surgery on the parotid gland (the large salivary gland in front of the ear) without using a wound drain.
- Conditions
- Parotid Neoplasms, Post-operative Complications, Seroma as Procedural Complication
- Trial name
- SNaPs (NCT07620184)
- Testing
- Active wound drainage (Standard of Care), Omission of active wound drain
- Where
- 3 sites in Sweden
- Volunteers
- 600 people
- Sponsor
- Uppsala University Hospital
Major Puerperal Infection, Postpartum, Wound Complications
Negative Pressure Wound Therapy After Cesarean Delivery
This study is aimed at determining whether or not the use of a wound suction device placed on the cesarean incision instead of a standard sterile dressing will decrease the prevalence of wound complications and wound infections…
- Conditions
- Major Puerperal Infection, Postpartum, Wound Complications, Wound Seroma, Caesarean Section Wound Separation
- Trial name
- NCT01637870
- Testing
- Prevena negative pressure wound system
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Abbey Hardy-Fairbanks
Surgical Wound Infection
Prophylactic Negative Wound Pressure Therapy (PICO-7) Following Groin Incisions in Vascular Surgery (PICO-Vasc Study)
Comparison between waterproof sterile dressing OPSITE Post-Op Visible, Smith \& Nephew, UK and PICO-7, Smith \& Nephew, UK in terms of inguinal surgical wound infection and complications after lower limb revascularization.
- Trial name
- PICO-Vasc (NCT04840576)
- Testing
- Regular waterproof sterile dressing., Prophylactic Negative Pressure Dressing
- Where
- Spain
- Volunteers
- 132 people
- Sponsor
- Corporacion Parc Tauli
Breast Cancer, Seroma
EvaLuating negAtive pressUre Wound theRapy in brEast coNserving Surgery
Negative pressure wound therapy (NPWT) could improve surgical outcomes and reduce complications like SSI, wound dehiscence and seroma in closed surgical wounds.
- Conditions
- Breast Cancer, Seroma, Wound Complication
- Trial name
- LAUREN (NCT05509829)
- Testing
- Negative pressure wound therapy
- Where
- Netherlands
- Volunteers
- 300 people
- Sponsor
- Zuyderland Medisch Centrum
Seroma, Wound Dehiscence
Prevention of Seroma Formation and Wound Complications Using NPWT Devices
The specific aim of this study is to improve post-operative wound care in the morbidly-obese body-contouring patient population following massive weight loss undergoing either panniculectomy or formal abdominoplasty, those…
- Conditions
- Seroma, Wound Dehiscence, Wound Infection
- Trial name
- NCT02147288
- Testing
- Renasys*GO Negative Pressure Wound Therapy System
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Yale University
Breast Reconstruction, Breast Cancer
Comparison of PEAK PlasmaBlade™ to Conventional Diathermy in Abdominal Based Free Flap Breast Reconstruction
Electrosurgery allows for dissection with simultaneous haemostasis. One of its disadvantages is that the heat production can cause injury to the surrounding tissue which may result in wound healing problems and an increased rate…
- Trial name
- NCT04350411
- Testing
- Conventional diathermy, PEAK PlasmaBlade™
- Where
- United Kingdom
- Volunteers
- 108 people
- Sponsor
- Anglia Ruskin University
Wounds, Infections
Acid Base and Electrolytes Patterns in Drains Operational Wounds and Its Relation to Complications
Objective- The purpose of this study is to evaluate a connection between PH,PCO2,HCO3,PO2,Na,K,Glu and Lactate patterns in vacuum drains of different plastic operational wounds and its relation to infections and seroma formation.
- Conditions
- Wounds, Infections, Seroma
- Trial name
- NCT01454167
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Breast Cancer - Female
Effects of Negative Pressure Wound Bandaging After Mastectomy
Participant information sheet: Mastectomy is a surgical method used to treat breast cancer. A mastectomy involves the removal of the entire breast. A common postoperative complication after a mastectomy is seroma, i.e.
- Trial name
- NEPTAM (NCT07607366)
- Testing
- PICO negative pressure wound therapy by Smith and Nephew
- Where
- Sweden
- Volunteers
- 76 people
- Sponsor
- Dalarna County Council, Sweden
Melanoma, Complication
Early Complications After Axillary and Inguinal Lymph Node Dissection in Stage III Melanoma Patients
This prospective randomized non-inferiority study is designed to compare the rate and severity of complications after axillary and inguinal lymph node dissection in stage III melanoma patients in a study group where the drain is…
- Trial name
- NCT04680182
- Testing
- Suction drain
- Where
- Norway
- Volunteers
- 104 people
- Sponsor
- Oslo University Hospital
Hernia Inguinal
A Comparative Study Between TAPP and Lichtenstein Techniques for Inguinal Hernia Surgery
This study is comperative study between TAPP And Lichtenstein Techniques for Inguinal Hernia surgery.The Lichtenstein tension-free open hernioplasty involves placing a tailored polypropylene mesh over the inguinal canal defect…
- Trial name
- NCT07067281
- Testing
- Lichtenstein Tension-Free Mesh Hernioplasty, Laparoscopic Transabdominal Preperitoneal (TAPP) Repair
- Where
- India
- Volunteers
- 60 people
- Sponsor
- GSVM Medical College
Cesarean Section, Surgical Site Infection
Steri-Strip Application Versus Standard Wound Closure for Cesarean Section Incisions
This study is evaluating whether Steri-Strips® provide additional benefits when used after cesarean section (C-section) surgery.
- Conditions
- Cesarean Section, Surgical Site Infection, Wound Dehiscence, Seroma
- Trial name
- STRIP-CS (NCT07686913)
- Testing
- Steri-Strip™ Skin Closures, Standard Cesarean Wound Closure
- Where
- United States
- Volunteers
- 610 people
- Sponsor
- Riverside University Health System Medical Center
Surgical Complication
The Effect of Local Application of Tranexamic Acid Versus Placebo on Postoperative Complications in Plastic Surgery
Study objective: This is a study to investigate whether applying the drug tranexamic acid (TXA) onto a surgical wound surface may affect the incidence of surgical complications such as re-bleeding needing intervention, wound…
- Trial name
- TRANOP (NCT06270407)
- Testing
- Tranexamic Acid 100 MG/ML, 0.9%sodium chloride
- Where
- 11 sites in Denmark, Finland and 1 more
- Volunteers
- 3,000 people
- Sponsor
- St. Olavs Hospital
Ventral Hernia, Incisional Hernia
Comparison of Sublay and Onlay Mesh Repair in Ventral Hernia
This study is designed to compare two different surgical methods for repairing ventral abdominal wall hernias: sublay mesh repair and onlay mesh repair.
- Trial name
- NCT07140471
- Testing
- Onlay Mesh Repair, Sublay Mesh Repair
- Where
- Pakistan
- Volunteers
- 96 people
- Sponsor
- Sana Ehsan ullah