Clinical trials: Wrinkle Appearance
Wrinkles
Silk'n HST for Wrinkle Reduction - Clinical Study Protocol
The objective of the study is to evaluate the safety, efficacy and usage compliance of the home-use device Silk'n HST for self-treatment of periorbital wrinkles and skin laxity and improvement of skin appearance.
- Trial name
- NCT02913547
- Testing
- Silk'n HST
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Home Skinovations Ltd.
Skin Aging
Evaluation of the Safety and Effectiveness of the Investigational Product in Improvement of the Appearance of Wrinkles and General Aspect of the Skin
The study investigates the safety and effectiveness of SILIMED® brand MEDGEL ANTIAGE with indication for improvement of the appearance of wrinkles and general aspects of the skin.
- Trial name
- NCT05997654
- Testing
- MEDGEL ANTIAGE
- Where
- Brazil
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Silimed Industria de Implantes Ltda
Wrinkle
Study to Identify if Saie Beauty's Under Eye Concealer Works to Improve Under-Eye Skin Appearance and Reduce Imperfections
Saie Beauty has developed 'Hydrabeam Sheer Brightening Under Eye Concealer' that is specifically designed for improving under-eye skin health.
- Trial name
- NCT05231681
- Testing
- Saie Beauty's Hydrabeam Sheer Brightening Under Eye Concealer
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Saie Beauty
Hair Loss/Baldness, Wrinkle Appearance
Autologous Adipose Cells Therapy
Autologous Adipose Cell Therapy is a series of process designated to address the demerits of the traditional autologous fat grafting and dermal fillers, while enhancing the versatility and aesthetic outcomes.
- Conditions
- Hair Loss/Baldness, Wrinkle Appearance, Volume, Fine Lines
- Trial name
- NCT06869252
- Testing
- Autologous Adipose Cells Therapy
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- CERM INC.
Skin Appearance, Skin Texture
Clinical Evaluation of a Multi-functional Beauty Device on Cosmetic Skin Outcomes
This study is designed to evaluate changes in cosmetic skin appearance and safety following at-home use of a multi-functional beauty device over a 4-week treatment period among approximately 50 participants.
- Conditions
- Skin Appearance, Skin Texture, Skin Sagging, Wrinkles
- Trial name
- NCT07871708
- Testing
- Multi-functional Home-use Beauty Device, Topical Skincare Serum, Skincare Mask
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- APR Co., Ltd.
Skin Aging
Proof of Concept Anti-ageing Clinical Study in Healthy Subjects
The objective of this POC clinical study is to evaluate the moisturising effects on fine lines and wrinkles, texture, barrier function, hydration and elasticity delivered by 4 weeks of twice daily application of the test product…
- Trial name
- NCT03180645
- Testing
- Test product (Moisturising cream), Positive control (Commercial market place moisturising cream), No treatment
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Age-related Changes in Skin Appearance and Physiology
Effect of Collagen Peptides on Skin Health: A Clinical Trial
The goal of this clinical trial is to evaluate whether daily oral supplementation with 2.5 g of specific bioactive collagen peptides (SCP) can improve skin physiology in healthy adult women aged 35-55 years.
- Trial name
- BCP-Skin (NCT07516756)
- Testing
- Specific Collagen Peptides
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Collagen Research Institute
Wrinkle
BTL-785F Device for Non-invasive Treatment of Wrinkles and Improvement of the Face Appearance
This study will evaluate the clinical safety and the performance of the BTL-785F system equipped with the BTL-785-7 applicator for non-invasive treatment of facial wrinkles.
- Trial name
- NCT05524805
- Testing
- BTL-785-7 Treatment
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Wrinkle
The Effects of a 5-Step Skin Regimen on Pigmentation and Appearance Related Biophysical Properties
This study is to analyze the effects of a 5-step skin care regimen on various skin parameters such as pigmentation, and firmness and elasticity of the skin around the eyes.
- Trial name
- NCT05688527
- Testing
- Cleansing Balm, Toning Essence, Facial Serum
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Wrinkle
BTL-785F Device for Non-invasive Reduction of Wrinkles and Overall Facial Improvement
This study will evaluate the clinical safety and the performance of the BTL-785F system equipped with the BTL-785-7 applicator for non-invasive treatment of facial wrinkles.
- Trial name
- NCT05524779
- Testing
- BTL-785-7
- Where
- 5 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Wrinkle, Aging
Study to Identify if Chemist Confessions Retinol Cream Works to Improve the Appearance of Early Signs of Aging.
Chemist Confessions has developed a retinol cream with the aim to improve the appearance of early signs of aging, such as fine lines, dark spots, hyperpigmentation, and crow's feet.
- Trial name
- NCT05039476
- Testing
- Retinol face cream
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Chemist Confessions, Inc.
Aging, Premature
Safety and Performance of DKL Crosslinked Sodium Hyaluronate 23 Dermal Filler for Improvement of NLF Appearance
This is a pivotal, prospective active-controlled, randomized, double blinded (blinded evaluator and subject), intra-individual split-face comparison, non-inferiority study of DKL crosslinked sodium hyaluronate 23 versus Juvederm…
- Trial name
- NCT05021913
- Testing
- DKL crosslinked sodium hyaluronate 23, Juvéderm Volift™ with lidocaine (Allergan, Inc)
- Where
- Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dr. Korman Laboratories Ltd.
Wrinkle Appearance, Skin Quality
A Study to Evaluate the Efficacy of Collagen 16 Serum Alone, Against and as an Adjunct to Radiesse® Biostimulation Procedure in Female Trial Participants With Aged Skin
This study aims at assessing the efficacy of improving skin aging signs of a serum containing collagen 16 combined with a biostimulation device in healthy female subjects aged between 30 and 70 years over a period of 13 weeks.
- Trial name
- NCT07446361
- Testing
- Group 1 (Biostimulation + Test product), Group 3 (Test product Alone)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Vichy Laboratoires
Facial Rhytides, Skin Folds, Loss of Volume and Skin Quality
A Study to Evaluate Participant Satisfaction With Facial Appearance Overall and the Aesthetic and Psychosocial Impact of Combined Facial Treatment
The objective of this study is to quantify the psychological and emotional impact of comprehensive aesthetic treatment with a portfolio of Allergan products by measuring the change in participant's satisfaction with facial…
- Trial name
- NCT03712449
- Testing
- JUVÉDERM®, BOTOX Cosmetic®, BELKYRA®
- Where
- 7 sites in Canada
- Volunteers
- 59 people
- Sponsor
- Allergan
Moderate to Severe Glabellar Lines
A Study to Assess the Effectiveness and Safety of IPN10200 in Adult Chinese Participants With Moderate to Severe Wrinkle-like Lines Between the Eyebrows
The purpose of this study is to find out about the effectiveness and safety of a single dose of corabotase (also known as IPN10200) compared to placebo works in participants with moderate to severe glabellar lines.
- Trial name
- LAURITE 3 (NCT07779252)
- Testing
- Corabotase
- Where
- 9 sites in China
- Volunteers
- 160 people
- Sponsor
- Ipsen
Skin Aging, Weight Loss
Effect of Revival Soy on Weight Loss and Skin, Hair, and Nails in Premenopausal Women
The purpose of this study is to determine if dietary consumption of Revival Soy can improve the appearance of the skin, hair, and finger nails and support weight loss in overweight, premenopausal women.
- Trial name
- NCT00352157
- Testing
- Revival Soy Dietary Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Physicians Pharmaceuticals, Inc.
Aging, Wrinkle Appearance
Anti-aging Efficacy Study on One Cosmetic Product Containing Mitopure
The aim of this study is to investigate the impact of a topical product on skin health and aging
- Trial name
- HCP-S1 (NCT07517887)
- Testing
- Skin care product
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Skin
A Double-Blind, Randomized, Placebo-Controlled Study Evaluating the Nutritional Supplement Lumenato and Its Impact on Skin Parameters in Healthy Female Subjects
The purpose of this study is to evaluate perceived changes in skin health and appearance after taking the study product daily for 12 weeks. The study product is a soft gel supplement containing tomato oil.
- Trial name
- NCT04356456
- Testing
- Lumenato
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- LycoRed Ltd.
Laser Therapy, Rejuvenation
Evaluation of Non-ablative and Fractional Combination Treatment for Improvement in Skin's Appearance
The study is designed to determine the safety, efficacy, patient comfort and patient satisfaction of the combined treatment of Refirme ST and Matrix RF both devices approved under 510k clearances.
- Trial name
- NCT01403597
- Testing
- Refirme ST Applicator and Matrix RF Applicator
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Forehead Wrinkles
Effectiveness and Safety Study of the Iovera Device for the Temporary Reduction in the Appearance of Forehead Wrinkles
Evaluate the effectiveness and safety of the iovera device for the temporary reduction in the appearance of forehead wrinkles.
- Trial name
- NCT01950065
- Testing
- iovera
- Where
- 6 sites in United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Pacira Pharmaceuticals, Inc