Clinical trials: Wrinkle Appearance
- Condition Wrinkle Appearance
- Funder type Industry (pharma, biotech, devices)
- Accepts healthy volunteers yes
Skin Aging
Proof of Concept Anti-ageing Clinical Study in Healthy Subjects
The objective of this POC clinical study is to evaluate the moisturising effects on fine lines and wrinkles, texture, barrier function, hydration and elasticity delivered by 4 weeks of twice daily application of the test product…
- Trial name
- NCT03180645
- Testing
- Test product (Moisturising cream), Positive control (Commercial market place moisturising cream), No treatment
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Wrinkles
Silk'n HST for Wrinkle Reduction - Clinical Study Protocol
The objective of the study is to evaluate the safety, efficacy and usage compliance of the home-use device Silk'n HST for self-treatment of periorbital wrinkles and skin laxity and improvement of skin appearance.
- Trial name
- NCT02913547
- Testing
- Silk'n HST
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Home Skinovations Ltd.
Wrinkle Appearance, Skin Quality
A Study to Evaluate the Efficacy of Collagen 16 Serum Alone, Against and as an Adjunct to Radiesse® Biostimulation Procedure in Female Trial Participants With Aged Skin
This study aims at assessing the efficacy of improving skin aging signs of a serum containing collagen 16 combined with a biostimulation device in healthy female subjects aged between 30 and 70 years over a period of 13 weeks.
- Trial name
- NCT07446361
- Testing
- Group 1 (Biostimulation + Test product), Group 3 (Test product Alone)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Vichy Laboratoires
Wrinkle
The Effects of a 5-Step Skin Regimen on Pigmentation and Appearance Related Biophysical Properties
This study is to analyze the effects of a 5-step skin care regimen on various skin parameters such as pigmentation, and firmness and elasticity of the skin around the eyes.
- Trial name
- NCT05688527
- Testing
- Cleansing Balm, Toning Essence, Facial Serum
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Laser Therapy, Rejuvenation
Evaluation of Non-ablative and Fractional Combination Treatment for Improvement in Skin's Appearance
The study is designed to determine the safety, efficacy, patient comfort and patient satisfaction of the combined treatment of Refirme ST and Matrix RF both devices approved under 510k clearances.
- Trial name
- NCT01403597
- Testing
- Refirme ST Applicator and Matrix RF Applicator
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Skin Appearance, Skin Texture
Clinical Evaluation of a Multi-functional Beauty Device on Cosmetic Skin Outcomes
This study is designed to evaluate changes in cosmetic skin appearance and safety following at-home use of a multi-functional beauty device over a 4-week treatment period among approximately 50 participants.
- Conditions
- Skin Appearance, Skin Texture, Skin Sagging, Wrinkles
- Trial name
- NCT07871708
- Testing
- Multi-functional Home-use Beauty Device, Topical Skincare Serum, Skincare Mask
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- APR Co., Ltd.
Wrinkle
BTL-785F Device for Non-invasive Treatment of Wrinkles and Improvement of the Face Appearance
This study will evaluate the clinical safety and the performance of the BTL-785F system equipped with the BTL-785-7 applicator for non-invasive treatment of facial wrinkles.
- Trial name
- NCT05524805
- Testing
- BTL-785-7 Treatment
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Forehead Wrinkles
Effectiveness and Safety Study of the Iovera Device for the Temporary Reduction in the Appearance of Forehead Wrinkles
Evaluate the effectiveness and safety of the iovera device for the temporary reduction in the appearance of forehead wrinkles.
- Trial name
- NCT01950065
- Testing
- iovera
- Where
- 6 sites in United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Pacira Pharmaceuticals, Inc
Appearance of Facial Wrinkles, Aesthetic
Evaluation of a Non-cross-linked Hyaluronic Acid Medical Device ("Electri" and "XELA REDERM") for Improving Facial Skin Appearance
The goal of this clinical investigation is to learn whether injectable implants based on non-cross-linked hyaluronic acid (Electri and XELA REDERM) improve the aesthetic appearance of facial skin in adult women.
- Conditions
- Appearance of Facial Wrinkles, Aesthetic, Hydration, Facial Skin Wrinkles
- Trial name
- RegHyal-01 (NCT06984432)
- Testing
- XELA REDERM (non-cross-linked hyaluronic acid 1.1%, 1.8%, or 2.2%), Electri (non-cross-linked hyaluronic acid 0.55%)
- Where
- 4 sites in Poland, Ukraine
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Institute Hyalual GmbH
Skin
A Double-Blind, Randomized, Placebo-Controlled Study Evaluating the Nutritional Supplement Lumenato and Its Impact on Skin Parameters in Healthy Female Subjects
The purpose of this study is to evaluate perceived changes in skin health and appearance after taking the study product daily for 12 weeks. The study product is a soft gel supplement containing tomato oil.
- Trial name
- NCT04356456
- Testing
- Lumenato
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- LycoRed Ltd.
Age-related Changes in Skin Appearance and Physiology
Effect of Collagen Peptides on Skin Health: A Clinical Trial
The goal of this clinical trial is to evaluate whether daily oral supplementation with 2.5 g of specific bioactive collagen peptides (SCP) can improve skin physiology in healthy adult women aged 35-55 years.
- Trial name
- BCP-Skin (NCT07516756)
- Testing
- Specific Collagen Peptides
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Collagen Research Institute
Aging, Premature
Safety and Performance of DKL Crosslinked Sodium Hyaluronate 23 Dermal Filler for Improvement of NLF Appearance
This is a pivotal, prospective active-controlled, randomized, double blinded (blinded evaluator and subject), intra-individual split-face comparison, non-inferiority study of DKL crosslinked sodium hyaluronate 23 versus Juvederm…
- Trial name
- NCT05021913
- Testing
- DKL crosslinked sodium hyaluronate 23, Juvéderm Volift™ with lidocaine (Allergan, Inc)
- Where
- Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dr. Korman Laboratories Ltd.
Skin Aging, Weight Loss
Effect of Revival Soy on Weight Loss and Skin, Hair, and Nails in Premenopausal Women
The purpose of this study is to determine if dietary consumption of Revival Soy can improve the appearance of the skin, hair, and finger nails and support weight loss in overweight, premenopausal women.
- Trial name
- NCT00352157
- Testing
- Revival Soy Dietary Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Physicians Pharmaceuticals, Inc.
Wrinkle
Study to Identify if Saie Beauty's Under Eye Concealer Works to Improve Under-Eye Skin Appearance and Reduce Imperfections
Saie Beauty has developed 'Hydrabeam Sheer Brightening Under Eye Concealer' that is specifically designed for improving under-eye skin health.
- Trial name
- NCT05231681
- Testing
- Saie Beauty's Hydrabeam Sheer Brightening Under Eye Concealer
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Saie Beauty
Appearance of Facial Wrinkles
Safety and Efficacy of Single Therapy Versus Double and Triple Therapy of the Pellevé™ Wrinkle Treatment System for the Treatment of Moderate Facial Wrinkles
The study will enroll and treat a patients to assess improvement in the appearance of facial wrinkles.
- Trial name
- NCT01299103
- Testing
- Pelleve Wrinkle Treatment System
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ellman International
Skin Aging
Evaluation of the Safety and Effectiveness of the Investigational Product in Improvement of the Appearance of Wrinkles and General Aspect of the Skin
The study investigates the safety and effectiveness of SILIMED® brand MEDGEL ANTIAGE with indication for improvement of the appearance of wrinkles and general aspects of the skin.
- Trial name
- NCT05997654
- Testing
- MEDGEL ANTIAGE
- Where
- Brazil
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Silimed Industria de Implantes Ltda
Wrinkle
BTL-785F Device for Non-invasive Reduction of Wrinkles and Overall Facial Improvement
This study will evaluate the clinical safety and the performance of the BTL-785F system equipped with the BTL-785-7 applicator for non-invasive treatment of facial wrinkles.
- Trial name
- NCT05524779
- Testing
- BTL-785-7
- Where
- 5 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Aging, Wrinkle Appearance
Anti-aging Efficacy Study on One Cosmetic Product Containing Mitopure
The aim of this study is to investigate the impact of a topical product on skin health and aging
- Trial name
- HCP-S1 (NCT07517887)
- Testing
- Skin care product
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Facial Skin Aging, Facial Volume Loss
Comparing Facial Aging Between Identical Twins With 3D Imaging
Identical twins share the same genes, which makes them a powerful way to study how lifestyle and environment - rather than genetics - affect how faces age.
- Conditions
- Facial Skin Aging, Facial Volume Loss, Wrinkle Appearance
- Trial name
- NCT07760532
- Testing
- GLP-1 Receptor Agonists
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ponsky Facial Aesthetics And Plastic Surgery, Llc
Wrinkle, Aging
Study to Identify if Chemist Confessions Retinol Cream Works to Improve the Appearance of Early Signs of Aging.
Chemist Confessions has developed a retinol cream with the aim to improve the appearance of early signs of aging, such as fine lines, dark spots, hyperpigmentation, and crow's feet.
- Trial name
- NCT05039476
- Testing
- Retinol face cream
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Chemist Confessions, Inc.