Clinical trials: acne
Acne Vulgaris
Efficacy of Silk - Like Bedding Fabric Pillow Case in the Treatment of Acne Vulgaris
The purpose of this research study is to better understand how this study pillowcase works when people use it to treat acne. Most people, including people with acne, sleep six to eight hours each night in direct contact with…
- Trial name
- NCT00767104
- Testing
- Silk like Pillowcase, Cotton Pillowcase
- Volunteers
- 40 people
- Sponsor
- Wake Forest University
Acne Vulgaris, Post Inflammatory Hyperpigmentation
The Use of Onexton in Moderate Acne Vulgaris for Patients With Skin of Color
This is a single-center, open label pilot study. The study is comprised of 5 study visits; Screening, Baseline, and Weeks 4, 8, and 16.
- Trial name
- NCT03402893
- Testing
- ONEXTON Topical Gel
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Derm Research, PLLC
Acne Vulgaris
To Study Generic Clindamycin 1%/Benzoyl Peroxide 5% Topical Gel (Glenmark Generics, Ltd) in the Treatment of Acne Vulgaris.
This is a randomized, double-blind, multiple-site, placebo-controlled, parallel-group study, designed to compare the efficacy and safety of generic Clindamycin 1%/ Benzoyl peroxide 5% topical gel (Glenmark Generics, Ltd), and the…
- Trial name
- NCT02465632
- Testing
- Clindamycin 1%/Benzoyl Peroxide 5% Topical Gel, BenzaClin® Topical Gel, Clindamycin 1%/Benzoyl Peroxide 5%
- Where
- 15 sites in United States, Belize
- Volunteers
- 1,100 people
- Sponsor
- Glenmark Pharmaceuticals Ltd. India
Acne
An Efficiency of a Moisturizer Containing Licochalcone A, L-carnitine and 1,2-decanediol With Adapalene Gel in Acne
Acne is an inflammation of sebaceous glands and follicles. Applying topical treatments such as adapalene gel may cause irritant adverse effects.
- Trial name
- NCT02173054
- Testing
- Adapalene gel with Eucerin, Adapalene gel
- Where
- Thailand
- Volunteers
- 120 people
- Sponsor
- Mahidol University
Acne Vulgaris
Dose Range Study of CD5789 in Acne Vulgaris
To assess the efficacy and safety of different concentrations of CD5789 cream in participants with acne vulgaris for the purpose of dose identification.
- Trial name
- NCT01616654
- Testing
- CD5789 25 µg/g cream, CD5789 50 µg/g cream, CD5789 100 µg/g cream
- Where
- 24 sites in United States
- Volunteers
- 304 people
- Sponsor
- Galderma R&D
Acne Vulgaris
A Study of the Safety, Engraftment, and Action of NB01 in Adults With Moderate Acne
Acne vulgaris is a multifactorial disease caused by overgrowth of Propionibacterium acnes (P. acnes), impaction of hair follicles, excessive sebum production and hormonal dysregulation.
- Trial name
- NCT03450369
- Testing
- NB01
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Naked Biome, Inc.
Scarring, Acne
Evaluation of the Cutera Enlighten™ Laser With Micro-Lens Array (MLA) Handpiece Attachment
The purpose of this pivotal investigation is to evaluate the efficacy and safety of the Cutera enlighten multi-wavelength 532 nm and 1064 nm picosecond pulse duration laser and an investigational micro-lens array (MLA) handpiece…
- Trial name
- NCT03430921
- Testing
- Enlighten™ Laser and a MLA Attachment
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Acne Vulgaris
Study of Efficacy and Safety of CJM112 in Patients With Moderate to Severe Inflammatory Acne
The study was designed primarily to assess preliminary efficacy and safety of CJM112 in patients with moderate to severe inflammatory acne and to determine if CJM112 has an adequate clinical profile for further clinical…
- Trial name
- NCT02998671
- Testing
- CJM112
- Where
- 10 sites in United States, Germany and 1 more
- Volunteers
- 52 people
- Sponsor
- Novartis Pharmaceuticals
Acne Vulgaris
Afamelanotide in Patients Suffering With Acne Vulgaris
This study aims to evaluate the effect of afamelanotide on the facial inflammatory acne-related lesions in patients with mild to moderate acne vulgaris, including tolerability of afamelanotide by patients with moderate acne…
- Trial name
- NCT04943159
- Testing
- Afamelanotide
- Volunteers
- 3 people
- Sponsor
- Clinuvel Pharmaceuticals Limited
Acne Vulgaris
Weekly Isotretinoin Therapy Study
In current Dermatology practice, options for moderate acne vulgaris remain limited. The mainstay of treatment for moderate acne remains long courses of oral antibiotics despite emerging antibiotic resistance.
- Trial name
- WIT (NCT04594759)
- Testing
- Isotretinoin
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Medical University of South Carolina
Acne
Clinical End Point Study of Generic Adapalene and Benzoyl Peroxide Gel Versus Epiduo® Forte Gel in Treatment of Acne Vulgaris
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Design, Multiple-Site Clinical Study to Evaluate the Therapeutic Equivalence and Safety of adapalene and benzoyl peroxide gel, 0.3%/2.5% (Actavis Laboratories UT, Inc.) to…
- Trial name
- NCT02651220
- Testing
- Epiduo® Forte Gel, Adapalene and Benzoyl Peroxide Gel
- Where
- 20 sites in United States, Belize
- Volunteers
- 1,001 people, healthy volunteers welcome
- Sponsor
- Actavis Inc.
Hidradenitis Suppurativa, Acne Inversa
A Study to Evaluate the Efficacy, Safety and Tolerability of Bermekimab in Patients With Hidradenitis Suppurativa
This study further evaluates the efficacy of bermekimab in treating moderate to severe hidradenitis suppurativa in adults. 1/3 of patients will receive weekly injections of bermekimab, 1/3 will receive alternating every other…
- Conditions
- Hidradenitis Suppurativa, Acne Inversa, Suppurative Hidradenitis
- Trial name
- NCT04019041
- Testing
- bermekimab
- Where
- 33 sites in United States
- Volunteers
- 153 people
- Sponsor
- Janssen Research & Development, LLC
Acne Vulgaris
CD5789 (Trifarotene) Long Term Safety Study on Acne Vulgaris
Multi-center, open-label, non-comparative safety and efficacy study with 52 Weeks of treatment on the face and trunk for acne vulgaris.
- Trial name
- NCT02189629
- Testing
- CD5789 (trifarotene)
- Where
- 32 sites in United States, Czechia and 2 more
- Volunteers
- 453 people
- Sponsor
- Galderma R&D
Acne Vulgaris
Comparison of Epiduo Associated With Lymecycline Versus Epiduo Vehicle Associated With Lymecycline in Acne Vulgaris
Randomized, controlled, multi-center, double-blind, parallel-group comparison study in Subjects with moderate to severe acne vulgaris on the face.
- Trial name
- TEAM (NCT01014689)
- Testing
- Adapalene/ BPO gel with Lymecycline capsules, Adapalene/ BPO vehicle gel with Lymecycline capsules
- Where
- 28 sites in Australia, Belgium and 7 more
- Volunteers
- 378 people
- Sponsor
- Galderma R&D
Acne Vulgaris
A Dose-ranging Study of DRM01 in Subjects With Acne Vulgaris
The objectives of this study are to assess the safety and efficacy DRM01 Topical Gel compared to vehicle in patients with acne vulgaris.
- Trial name
- NCT02431052
- Testing
- Olumacostat Glasaretil, Vehicle
- Where
- 34 sites in United States, Canada
- Volunteers
- 420 people
- Sponsor
- Dermira, Inc.
Acne
Adapalene-Benzoy Peroxide (BPO) Gel in the Treatment of Acne Vulgaris as a 6-month Maintenance
The purpose of this study is to demonstrate the efficacy of Adapalene 0.1% /Benzoyl Peroxide 2.5% Gel compared to its Vehicle Gel as an acne maintenance treatment in Subjects previously treated with Adapalene-BPO Gel or…
- Trial name
- ACCESS II (NCT00687908)
- Testing
- Adapalene 0.1% / Benzoyl Peroxide 2.5% Gel, Vehicle Gel
- Where
- 33 sites in United States, Canada and 1 more
- Volunteers
- 243 people
- Sponsor
- Galderma R&D
Acne Vulgaris
A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Participants With Acne Vulgaris
Efficacy and Safety of Imsidolimab in Participants with Acne Vulgaris
- Trial name
- NCT04856917
- Testing
- Imsidolimab
- Where
- 15 sites in United States, Canada
- Volunteers
- 123 people
- Sponsor
- Vanda Pharmaceuticals
Acne Vulgaris
Clinical Study Comparing the Efficacy and Safety of IDP-126 Gel in the Treatment of Acne Vulgaris
This is a multicenter, randomized, double-blind, vehicle-controlled, 12-week study designed to assess the safety, tolerability, and efficacy of IDP-126 Gel in comparison IDP-126 Vehicle Gel at Weeks 2, 4, 8, and 12.
- Trial name
- NCT04214639
- Testing
- IDP-126 Gel, IDP-126 Vehicle Gel
- Where
- 13 sites in United States, Canada
- Volunteers
- 183 people
- Sponsor
- Bausch Health Americas, Inc.
Acne
Comparative Safety and Efficacy of Two Treatments in the Treatment of Acne Vulgaris
The purpose of this study is to compare the safety and efficacy of Perrigo's product to an FDA approved product for the treatment acne vulgaris
- Trial name
- NCT02515305
- Testing
- Clindamycin and Benzoyl Peroxide Gel (combination), Clindamycin and Benzoyl Peroxide Gel (Reference) (combination)
- Where
- United States
- Volunteers
- 890 people
- Sponsor
- Padagis LLC
Acne Vulgaris
Clinical Trial in Subjects With Mild to Moderate Acne Vulgaris
The purpose of this study is to demonstrate the safety, tolerability and efficacy of B244 administered over 12 weeks to participants with mild to moderate acne vulgaris relative to placebo.
- Trial name
- NCT02832063
- Testing
- B244
- Where
- United States
- Volunteers
- 372 people
- Sponsor
- AOBiome LLC