Clinical trials: asthma
Inhaled Steroid-Dependent Asthma
Bridging the Gap Between Prescription and Practice: Impact of Nurse-Led Inhaler Education
Asthma and chronic obstructive pulmonary disease (COPD) are among the most prevalent chronic respiratory conditions worldwide, affecting hundreds of millions of individuals and contributing substantially to morbidity, mortality…
- Trial name
- NCT07442617
- Testing
- Inhaler technique
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University Hospital
Arthritis, Asthma
Mobility Assessment in Multi-morbidity
Multimorbidity (the presence of two or more coexisting long-term conditions) is a significant challenge facing the NHS, especially given UK's ageing population and the association with high levels of illness burden and healthcare…
- Conditions
- Arthritis, Asthma, Atrial Fibrillation, Bronchiectasis
- Trial name
- Multi-mobility (NCT06473168)
- Volunteers
- 55 people
- Sponsor
- Northumbria University
Asthma in Children
Scaling up the Integrated Care Pathway for Acute Asthma to All Osakidetza Pediatric Services Through a Cluster-randomized SMART Design
The main goal of this study is to evaluate the effectiveness of adaptive sequential implementation strategies based on facilitation in promoting the sustainable and widespread adoption and scaling up of the Integrated Care…
- Trial name
- NCT07642388
- Testing
- Internal + External Facilitation for Implementation, Internal + External Facilitation for Sustainability, Internal Facilitation
- Where
- Spain
- Volunteers
- 4,680 people
- Sponsor
- Basque Health Service
Asthma, Asthma Attack
Individualizing Treatment for Asthma in Primary Care (Full Study)
While asthma therapy is becoming more individualized based on asthma phenotypes, more research is needed to tailor newer therapies to individuals.
- Conditions
- Asthma, Asthma Attack, Asthma Exacerbations
- Trial name
- iTREAT-PC (NCT07052942)
- Testing
- Inhaled corticosteroid (ICS), Azithromycin, Asthma Symptom Monitoring Web-based Application
- Where
- 13 sites in United States
- Volunteers
- 3,200 people
- Sponsor
- DARTNet Institute
Bronchial Asthma
Assessment of Asthma Exacerbation in Children by Modified Pulmonary Index Score
Asthma is a heterogeneous disease, usually characterized by chronic airway inflammation. It is defined by the history of respiratory symptoms such as wheeze, shortness of breath, chest tightness and cough that vary over time and…
- Trial name
- NCT03190759
- Volunteers
- 1 people
- Sponsor
- Assiut University
Allergic Bronchopulmonary Aspergillosis, ABPA
Real-World Effectiveness of Depemokimab in Allergic Bronchopulmonary Aspergillosis With Severe Eosinophilic Asthma
An open-label study will evaluate effects of Depemokimab in the treatment of severe eosinophilic asthma in patients with allergic bronchopulmonary aspergillosis
- Conditions
- Allergic Bronchopulmonary Aspergillosis, ABPA, Severe Eosinophilic Asthma
- Trial name
- NCT07828327
- Testing
- Depemokimab
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Qianfoshan Hospital
Asthma
Exhaled Breath Condensate as a Measure of Airway Inflammation in Children With Asthma
This study will evaluate the usefulness of a new procedure for evaluating asthma in children. The method measures the pH (a measure of acidity and alkalinity) of exhaled breath condensate (water vapor created by the lungs).
- Trial name
- NCT00078208
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Asthma
Study of the Effect of Mometasone Furoate/Formoterol (MF/F), Montelukast and Beclomethasone Dipropionate (BDP) on Plasma Cortisol Levels of Children 5-11 Years Old With Persistent Asthma (P05574)
The purpose of this study is to assess the effect of one of five possible study medications used in the treatment of asthma on blood plasma cortisol levels in children aged 5-11 years with persistent asthma.
- Trial name
- NCT01615874
- Testing
- MF/F Metered Dose Inhaler (MDI) 25/5 mcg, MF/F MDI 50/5 mcg, MF/F MDI 100/5 mcg
- Sponsor
- Organon and Co
Asthma
Evaluation of an Asthma Treatment Strategy Based on Exhaled Nitric Oxide Measurements in Adolescents
The purpose of ICAC-01 is to determine whether an asthma treatment strategy that measures exhaled nitric oxide (eNO) to indicate disease progression is more effective in treating asthma symptoms when combined with existing asthma…
- Trial name
- NCT00114413
- Testing
- Inhaled corticosteroids, eNO measurement
- Where
- 12 sites in United States
- Volunteers
- 547 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Bronchial Asthma
Treatment of Bronchial Asthma With Borage and Echium Seed Oils
The aim of this trial is to determine the efficacy of a combination of two botanicals oils, borage seed oil and echium seed oil, as a potential treatment for bronchial asthma.
- Trial name
- NCT00806442
- Testing
- Borage Seed Oil and Echium Seed Oil, Corn Oil
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Brigham and Women's Hospital
Asthma
Clinical Trial on Education Method of Fluterol® Inhalation Inhaler for Asthma Control
A multi-center, randomized, open, non-inferiority, Phase 4 study
- Trial name
- NCT03110874
- Testing
- one-way education, two-way education
- Volunteers
- 184 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Asthma
Protocol CAUSE-03 / CHEETAH
This is a one-year longitudinal, observational study of 250 urban children and adolescents with asthma and 60 without asthma, ages 6-17 years old.
- Trial name
- CHEETAH (NCT06136091)
- Where
- 8 sites in United States
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Atrial Fibrillation (AF), Heart Failure
Somatic Health Screening for Adults in Outpatient Psychiatric Care in Denmark (SomaScreen)
People with severe mental illness have a substantially increased risk of undiagnosed and insufficiently treated somatic disease.
- Conditions
- Atrial Fibrillation (AF), Heart Failure, Asthma (Diagnosis), Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- SomaScreen (NCT07518446)
- Testing
- Somatic Health Screening for Adults in Outpatient Psychiatric Care in Denmark (SomaScreen)
- Where
- Denmark
- Volunteers
- 2,800 people
- Sponsor
- Amager Hospital
Asthma in Children
Using Social Media to Decrease Healthcare Utilization for Pediatric Asthma
The purpose of this study is to evaluate if social media enhanced education (SME) will reduce total number of treatment days defined as summation of days of subsequent hospital admission, emergency room visits, and clinic visits…
- Trial name
- NCT05013788
- Testing
- Social Media Enhanced Education, Usual Asthma Education
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- The University of Texas Health Science Center, Houston
Asthma, Bronchial Diseases
Individualizing Treatment for Asthma in Primary Care
This is a patient level randomized trial for teenagers and adults with asthma who will be randomized to four arms - enhance usual care, rescue inhaled corticosteroids, azithromycin and both rescue inhaled corticosteroids and…
- Conditions
- Asthma, Bronchial Diseases, Respiratory Tract Infections, Lung Diseases, Obstructive
- Trial name
- iTREAT-PC (NCT06272370)
- Testing
- Asthma Symptom Monitoring online tools, Inhaled Steroids, Azithromycin Pill
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- DARTNet Institute
Asthma
An Observational Study of the Use and Safety of Xolair® During Pregnancy
The Xolair® Pregnancy Registry is an observational study established by Genentech to obtain data on pregnancy outcomes in women who are exposed to Xolair®.
- Trial name
- EXPECT (NCT00373061)
- Testing
- Xolair®
- Where
- United States
- Volunteers
- 309 people
- Sponsor
- Genentech, Inc.
Asthma
A Study to Assess the Effects of Fluticasone Furoate and GW642444M Combination in Healthy Subjects and in Subjects With Mild, Moderate or Severe Hepatic Impairment.
In relation to their severity, hepatic diseases can significantly modify drug absorption and disposition and consequently can interfere with drug efficacy and/or produce toxicity.
- Trial name
- NCT01266941
- Testing
- Inhaled FF 200mcg/GW642444M 25mcg
- Where
- 3 sites in Czechia, Slovakia
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Asthma, Allergy
Dietary Interventions in Asthma Treatment: Sprouts Study
Sulforaphane (SFN) is a naturally occurring isothiocyanate that is a potent inducer of Phase II enzymes which play a critical role in preventing oxidative stress (via activation of Nrf2).
- Trial name
- NCT01183923
- Testing
- Broccoli Sprouts, Alfalfa Sprouts
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Johns Hopkins University
Asthma
Specific Use-Result of Spiriva Respimat® in Asthmatics
The study objective is to investigate the safety and effectiveness of Spiriva Respimat in patients with mild to moderate persistent asthma under real-world use
- Trial name
- NCT03188120
- Testing
- Spiriva Respimat
- Where
- Japan
- Volunteers
- 193 people
- Sponsor
- Boehringer Ingelheim
Asthma, Hypertension
Implementation of an Asthma Program to Improve Asthma Identification and Education in Children
The primary objective of this study is to document the prevalence and associations between asthma, hypertension, and obesity in children living in Pittsburgh, Pennsylvania and its surrounding regions.
- Conditions
- Asthma, Hypertension, Obesity
- Trial name
- NCT01692080
- Testing
- Asthma education
- Where
- United States
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Duquesne University
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