Clinical trials: asthma
Asthma
Community Empowerment to Pilot a Novel Device for Monitoring Rescue Medication Use in Urban Children With Asthma
Background: Pediatric asthma is the most common chronic illness among children and is associated with poor quality of life, activity restriction, school absences, and thousands of physician visits annually.
- Trial name
- NCT02517047
- Testing
- CareTRx
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Boston Children's Hospital
Asthma
A Study of the Effectiveness and Safety of Different Doses of Fluticasone Propionate Taken From a Dry Powder Inhaler in Adolescents and Adults Who Have Asthma That is Not Controlled by Asthma Medications Not Containing Steroids
This is a randomized, double-blind, placebo- and open-label active controlled, parallel-group, multicenter, dose ranging study in male or female subjects ages 12 years and older with persistent asthma who are uncontrolled on…
- Trial name
- NCT01479621
- Testing
- Fp MDPI, Flovent Diskus, albuterol/salbutamol
- Where
- 189 sites in United States, Bulgaria and 7 more
- Volunteers
- 909 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Chest Wall Oscillation for Asthma and COPD Exacerbations Trial (COAT)
The objective of this study was to evaluate the use of high frequency chest wall oscillation (HFCWO) early in the treatment of adults hospitalized for acute asthma or chronic obstructive pulmonary disease (COPD).
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease (COPD), Undifferentiated Asthma/COPD
- Trial name
- NCT00181285
- Testing
- High Frequency Chest Wall Oscillator
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Chicago
Uncontrolled Asthma, Young Adults
Medication Adherence With Telehealthcare Medication Therapy Management
Improving Medication Adherence with Telehealthcare Medication Therapy Management to Change Health Outcomes in Adolescents and Young Adults with Asthma (MATCH) is a multi-center, randomized parallel group study targeted to an…
- Trial name
- MATCH (NCT03978936)
- Testing
- Medication Therapy Management (MTM) Video Telehealthcare, Electronic Adherence Self-Management (EAM)
- Where
- 21 sites in United States
- Volunteers
- 375 people
- Sponsor
- Johns Hopkins University
Healthy, Cystic Fibrosis (CF)
MRI for Non-Invasive Imaging in Neonates and Children
The purpose of this study is to develop rapid MRI techniques for imaging the lung with hyperpolarized helium-3 gas as an inhaled contrast agent.
- Conditions
- Healthy, Cystic Fibrosis (CF), Asthma, Bronchopulmonary Dysplasia (BPD)
- Trial name
- NCT02163681
- Testing
- Hyperpolarized Helium-3 MRI of the chest
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Asthma
Evaluation of Tiotropium 5 µg/Day Delivered Via the Respimat® Inhaler Over 48 Weeks in Patients With Severe Persistent Asthma on Top of Usual Care (Study I)
The trial is a randomised, double-blind, placebo-controlled, parallel-group trial to evaluate the efficacy and safety of 5 µg tiotropium over a 48-week treatment period as compared to placebo.
- Trial name
- NCT00772538
- Testing
- tiotropium 5mcg/day
- Where
- 73 sites in United States, Australia and 12 more
- Volunteers
- 459 people
- Sponsor
- Boehringer Ingelheim
Asthma
Flexibility and Strength Training in Asthma
The aim of the study is proof of concept and to establish the feasibility of performing a study of resistive flexibility and strength training (RFST) in patients with asthma, with the future goal of designing a larger randomized…
- Trial name
- FASTA (NCT02370004)
- Testing
- Resistive Flexibility and Strength Training
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Brigham and Women's Hospital
Exercise Induced Asthma
Comparing Symbicort® As-Needed or Bricanyl As-Needed or Pulmicort® Once Daily + Bricanyl As-Needed in Asthma Patients
1. The primary objective of this study is: To evaluate the magnitude of the protective effect of the combination of budesonide and formoterol on an as-needed basis compared to the use of terbutaline as-needed on exercise induced…
- Trial name
- MIA (NCT00989833)
- Testing
- budesonide, terbutaline, budesonide/formoterol
- Where
- 10 sites in Norway, Sweden
- Volunteers
- 66 people
- Sponsor
- AstraZeneca
Asthma
Effect of Symbicort on GR Localisation in Asthma
To investigate a possible interaction between formoterol and budesonide on GR-translocation and to compare the effect of different doses of Symbicort (80/4.5 and 2x80/4.5 mcg) with the effect of budesonide (200 mcg and 800 mcg)…
- Trial name
- NCT00159263
- Testing
- Formoterol Inhalant Powder, Budesonide Powder, Budesonide and Formoterol Product
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Imperial College London
Asthma
physicAl aCtiviTy In minOrity womeN With Asthma Intervention
The ACTION intervention: physicAl aCtiviTy In minOrity womeN with asthma is a 3lifestyle physical activity intervention refined to be applicable for sedentary African American (AA) women with asthma.
- Trial name
- ACTION (NCT03265665)
- Testing
- ACTION Intervention, Enhanced usual care
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of Illinois Chicago
Asthma
iTRACC (Improving Technology-Assisted Recording of Asthma Control in Children)
The goal of this study is to determine whether a sensor-enabled, clinically integrated, mobile health asthma program can improve asthma outcomes among 4-17 year old children with moderate-to-severe asthma.
- Trial name
- iTRACC (NCT02994238)
- Testing
- Remote Health Management Sensor Platform
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Dr. Deneen Vojta
Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention, Heart Disease
Social Work Intervention Focused on Transitions
In response to Program Announcement (PA)-09-164, "NIH Exploratory/Developmental Research Grant Program (R21) a randomized pilot study testing the efficacy of SWIFT: Social Work Intervention Focused on Transitions among at-risk…
- Conditions
- Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention, Heart Disease, Diabetes, Hypertension
- Trial name
- SWIFT (NCT02232126)
- Testing
- SWIFT home intervention
- Where
- 2 sites in United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Asthma
Text2Breathe: Enhance Parent Communication to Reduce Pediatric Asthma Disparities
Text2Breathe (T2B) is a randomized controlled trial aimed at improving communication between parents and their children's' primary care providers about asthma.
- Trial name
- T2B (NCT03032159)
- Testing
- Text2Breathe Study Group
- Where
- 2 sites in United States
- Volunteers
- 221 people
- Sponsor
- Seattle Children's Hospital
Asthma
A Safety and Efficacy Study of Tralokinumab in Adults With Asthma
The purpose of this study is to determine whether the addition of tralokinumab to standard asthma medication is effective in the treatment of adults with asthma.
- Trial name
- NCT01402986
- Testing
- Tralokinumab 300 mg, Q2W, Tralokinumab 300 mg, Q2/4W
- Where
- 89 sites in United States, Argentina and 13 more
- Volunteers
- 689 people
- Sponsor
- MedImmune LLC
Asthma
PEEP as Rescue Therapy for Asthmatics With Elevated BMI
The purpose of this study is to test the effect of increasing lung volume with a simple hand-held device to both prevent, and also to relieve, airway constriction in people with asthma and a BMI ≥ 30 kg/m2.
- Trial name
- NCT02696980
- Testing
- Positive Expiratory Pressure
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Vermont
Asthma
Effectiveness of Chinese Herbal Therapy for Asthma
The purpose of this study is to determine the efficacy of an anti-asthma herbal medicine intervention (ASHMI) in adult asthmatics
- Trial name
- NCT00712296
- Testing
- ASHMI 4, ASHMI 12
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Asthma, COPD
The Natural History of Small Airways Physiology in Diseased and Healthy States
Spirometry is a useful clinical tool for the assessment and monitoring of lung disease, however, it does not provide information on peripheral airways resistance.
- Conditions
- Asthma, COPD, Interstitial Lung Disease, Cystic Fibrosis
- Trial name
- NCT00677560
- Where
- United Kingdom
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Asthma, Diabetes Mellitus
A One Year Clinical Trial Assessing the Usefulness and Safety of Inhaled Insulin in Diabetics With Asthma
A One Year Clinical Trial Assessing the Usefulness and Safety of Inhaled Insulin in Diabetics with Asthma
- Trial name
- NCT00139659
- Testing
- Inhaled Insulin, Subcutaneous Insulin
- Where
- 102 sites in United States, Brazil and 3 more
- Volunteers
- 288 people
- Sponsor
- Pfizer
Asthma
Safety and Efficacy of GW685698X an Inhaled Corticosteroid Once Daily and Twice Daily for the Treatment of Asthma
The purpose of this study is to compare once and twice daily GW685698 in asthma
- Trial name
- NCT00766090
- Testing
- GW685698X
- Where
- 16 sites in United States
- Volunteers
- 190 people
- Sponsor
- GlaxoSmithKline
Asthma, Croup
Comparison of Dexamethasone Oral Preparations to Assess Taste and Acceptance in Children With Asthma and Croup
Study of the palatability and acceptability of dexamethasone oral tablets crushed and placed in apple sauce or pudding in comparison with the IV solution mixed with sugar syrup and given orally.
- Trial name
- NCT03705273
- Testing
- Dexamethasone IV for PO, Dexamethasone crushed tablets
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Vanderbilt University Medical Center
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