Clinical trials: psoriasis
Evaluate Bone Changes in Patients With PsA
Abatacept Bone Effects in Psoriatic Arthritis With Bone Biomarker
Observation has pointed out, that osteitis present in the MRI scans, predicts bone erosion and that this in accordance with the concept by underlining the importance of bone marrow involvement in arthritis [Krabben A, 2013].
- Trial name
- NCT04106804
- Testing
- Abatacept 125 MG/ML
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Psoriasis Vulgaris
The Efficacy Of A Dead Sea Mineral Enriched Body Cream vs Its Carrier as an Adjuvant Treatment For Psoriatic Patients
This is a two-center study aimed to assess the efficacy of Dead Sea Minerals in alleviating symptoms of Psoriasis Vulgaris, in 50 patients undergoing phototherapy.
- Trial name
- NCT01651559
- Where
- 2 sites in Israel
- Volunteers
- 50 people
- Sponsor
- Ahava Dead Sea Laboratories
Bullous Dermatoses, Psoriasis
Intradermal Tozinameran for Patients With Immune-mediated Dermatologic Diseases
This is a randomised controlled trial conducted to prove that the immunological performance of intradermal tozinameran (i.e., Pfizer-BioNTech COVID-19 vaccine) is no worse than the standard intramuscular route in patients with…
- Conditions
- Bullous Dermatoses, Psoriasis, COVID-19 Vaccines
- Trial name
- NCT05406908
- Testing
- tozinameran
- Where
- Thailand
- Volunteers
- 109 people
- Sponsor
- Mahidol University
Psoriasis
Genomic Study for the Prediction of Efficacy and Adverse Effects of CD11a Monoclonal Antibodies(Raptiva)
The pathogenesis of psoriasis has evolved from epidermal hyperproliferation to immune dysregulation in recent years. A Th1 cytokine profile is universally found is psoriasis.
- Trial name
- NCT00602823
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Chronic Plaque-type Psoriasis
Comparison of Secukinumab Versus Guselkumab in Clearing Psoriatic Plaques Refractory to Ustekinumab
The aim of this study was to describe the effect of direct IL-17A inhibition with secukinumab as compared with the selective inhibition of IL-23 with guselkumab (p19 subunit blocker) in controlling inflammation in psoriatic…
- Trial name
- ARROW (NCT03553823)
- Testing
- Skin biopsies
- Where
- 14 sites in United States, Canada and 1 more
- Volunteers
- 40 people
- Sponsor
- Novartis Pharmaceuticals
Psoriasis (PsO), Randomised Controlled Trial
Sulodexide in Controlling the Recurrence of Psoriasis
This is a multicenter, randomized, double-blinded，controlled clinical trial. The purpose of the study is to evaluate the efficacy and safety of Sulodexide versus placebo in preventing psoriasis recurrence in patients with plaque…
- Trial name
- NCT06982196
- Testing
- Sulodexide
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Xijing Hospital
Psoriasis
Impact of Clinical and Psychological Factors on Satisfaction With Treatment in Psoriatic Patients on Biological Therapy
Psoriasis is a chronic-recurrent inflammatory disease with a significant impact on patients' physical and psychological well-being.
- Trial name
- PsoSAT (NCT07498543)
- Testing
- Questionnaire
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Catholic University of the Sacred Heart
Psoriatic Arthritis
To Evaluate the Efficacy and Safety of SHR0302 Tablet in Subjects of Active Psoriatic Arthritis
This study is a phase 3 study,to evaluate the efficacy and safety of different doses of JAK1 inhibitor SHR0302 in subjects with active psoriatic arthritis.
- Trial name
- NCT04957550
- Where
- China
- Volunteers
- 418 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Psoriasis, Aging
Effects of Tildrakizumab on Epigenetic Age
Design: Single-center open-label clinical trial. Objective: Evaluate if tildrakizumab reverses peripheral blood leukocyte DNA methylation (epigenetic aging) observed in chronic psoriasis. Number of subjects: 30.
- Conditions
- Psoriasis, Aging, Epigenetic Disorder, Inflammation; Skin
- Trial name
- NCT05110313
- Testing
- TILDRAKIZUMAB
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Carlos Wambier
Crohn's Disease, Rheumatoid Arthritis
OTIS Cimzia Pregnancy Registry
The purpose of the OTIS Autoimmune Diseases in Pregnancy Study is to monitor planned and unplanned pregnancies exposed to certain medications, to evaluate the possible teratogenic effect of these medications and to follow live…
- Conditions
- Crohn's Disease, Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis
- Trial name
- NCT01797224
- Where
- United States
- Volunteers
- 925 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Psoriatic Arthritis
Clinical Impact of Acthar in the Psoriatic Arthritis Patient (CLIPS)
Demonstrate the clinical value of Acthar TM in patients with active Psoriatic Arthritis who lack adequate response to DMARDS, and the quantification of response by clinical, serologic and structural parameters.
- Trial name
- CLIPS (NCT03419650)
- Testing
- ACTHar
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- IRIS Research and Development, LLC
Scalp Psoriasis, Pustular Palmo-plantar Psoriasis
IL-17 Role in Variants of Psoriasis
The goal of this project is to study some mechanisms involved in the dysregulation of the immune system observed in the skin of subjects with psoriasis.
- Conditions
- Scalp Psoriasis, Pustular Palmo-plantar Psoriasis, Non-pustular Palmo-plantar Psoriasis, Elbow Psoriasis
- Trial name
- NCT02078297
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Innovaderm Research Inc.
Psoriasis, Psoriatic Arthritis
Effectiveness of Interdisciplinary Care Compared to Usual Care in Patients With Immune-Mediated Inflammatory Diseases
The overall aim of this study is to determine the effectiveness of an interdisciplinary combined clinic intervention compared to usual care in a population of patients with two or more Immune-mediated inflammatory diseases…
- Conditions
- Psoriasis, Psoriatic Arthritis, Axial Spondyloarthritis, Hidradenitis Suppurativa
- Trial name
- NCAS-1 (NCT04200690)
- Testing
- Interdisciplinary management, Usual-care management
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- University of Aarhus
Plaque Psoriasis
A Phase 3 Study in Moderate-to-Severe Plaque Psoriasis With Piclidenoson to Study Safety and Efficacy
This is a double-blind, placebo-controlled study in adults with a diagnosis of moderate-to-severe chronic plaque psoriasis to test the efficacy and safety of piclidenoson in this patient population.
- Trial name
- NCT06643260
- Testing
- piclidenoson
- Volunteers
- 705 people
- Sponsor
- Can-Fite BioPharma
Nail Psoriasis, Plaque Psoriasis
A Study to Evaluate the Safety and Efficacy of Adalimumab in Subjects With Chronic Plaque Psoriasis and Nail Psoriasis
This study is being conducted to assess the safety and efficacy of adalimumab in participants with nail psoriasis.
- Trial name
- NCT02016482
- Testing
- Adalimumab
- Volunteers
- 217 people
- Sponsor
- AbbVie
Psoriasis
Spanish Registry of Systemic Treatments in Psoriasis
The purpose of Biobadaderm is a to study the safety of systemic therapy in psoriasis.
- Trial name
- Biobadaderm (NCT02075697)
- Where
- 13 sites in Spain
- Volunteers
- 3,500 people
- Sponsor
- Fundación Academia Española de Dermatología
Plaque Psoriasis
Monocyte Biomarkers in Moderate to Severe Plaque Psoriasis Subjects Treated With Apremilast
This is an open label pilot study of the impact of treatment with standard dosing of Otezla for 16 weeks on AM-endotype psoriasis patients, identified by elevated (>150% of normal): 1.) Intermediate (CD14++CD16+) monocytes, or…
- Trial name
- NCT03442088
- Testing
- Apremilast
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University Hospitals Cleveland Medical Center
Rheumatoid Arthritis (RA), Atopic Dermatitis (AD)
A Study of Oral Upadacitinib (RINVOQ) Tablets to Assess Adverse Events and Change in Disease Symptoms in Korean Participants With Moderate to Severe Active Rheumatoid Arthritis, Atopic Dermatitis, Ankylosing Spondylitis or Psoriatic Arthritis
Rheumatoid Arthritis (RA) is an inflammatory disease of the joints characterized by the swelling of multiple joints and tenderness caused by progressive inflammatory synovitis, which leads to serious and debilitating diseases.
- Conditions
- Rheumatoid Arthritis (RA), Atopic Dermatitis (AD), Ankylosing Spondylitis (AS), Psoriatic Arthritis (PsA)
- Trial name
- NCT04541810
- Where
- 116 sites in South Korea
- Volunteers
- 2,369 people
- Sponsor
- AbbVie
Psoriasis
A Survey on the Role and Benefits of Online Social Networks on Filipino Patients With Psoriasis
With the rise of usage of the internet, online social networks have recently been gaining popularity. Joining these groups can be beneficial to patients with chronic medical illness, such as psoriasis.This was a cross-sectional…
- Trial name
- NCT01465061
- Testing
- Online support group
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of the Philippines
Generalized Pustular Psoriasis, Erythrodermic Psoriasis
A Study of Ixekizumab (LY2439821) in Participants in Japan With Generalized Pustular Psoriasis and Erythrodermic Psoriasis
The reason for this study is to see if the study drug ixekizumab is safe and effective in participants with generalized pustular psoriasis and erythrodermic psoriasis.
- Trial name
- NCT03942042
- Testing
- Ixekizumab
- Where
- 7 sites in Japan
- Volunteers
- 12 people
- Sponsor
- Eli Lilly and Company
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