Clinical trials: the Diabetic Process
Diabetic Foot Infections, Chronic Venous Insufficiency
Clinical Study in Adult Patients With Purulent-inflammatory Processes of the Skin and Soft Tissues, Phase I-II of the Wound Process
The purpose of this study is to estimate efficiency, tolerance, safety of "Foscelantan, medicinal plate 4.0x5.0 cm in package No.
- Trial name
- OLENKRON-01 (NCT06232421)
- Testing
- Foscelantan, Povidon-iodine
- Where
- 2 sites in Belarus
- Volunteers
- 224 people
- Sponsor
- Research Institute for Physical Chemical Problems of the Belarusian State University
Diabetes Mellitus
Pain and Comfort in Diabetic Foot Ulcer Care
The purpose of this study is to reveal the effect of cold application of 0.9% NaCl solution used during diabetic foot ulcer (DFU) care on the pain and comfort levels of patients.
- Trial name
- NCT06644235
- Testing
- Cold Application
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Mardin Artuklu University
Peripheral Arterial Disease, Diabetic Foot
Efficacy and Safety of Intramuscular PDA-002 in Subjects With Diabetic Foot Ulcer With and Without PAD.
This is a Phase 2, multicenter, randomized, double-blind, placebo-controlled, dose-ranging study evaluating the efficacy and safety of intramuscular administration of human placenta-derived cells (PDA-002) in subjects with…
- Trial name
- DFU-002 (NCT02264288)
- Testing
- PDA-002
- Where
- 45 sites in United States
- Volunteers
- 159 people
- Sponsor
- Celularity Incorporated
Diabetic Foot Ulcer, Diabetic Foot
Modified Platform Trial Evaluating PpLHACM and SOC Versus SOC Alone in the Treatment of Nonhealing DFUs
This study will evaluate two human amnion/chorion membrane (ppLHACM) products and Standard of Care (SOC) versus SOC alone in the closure of nonhealing diabetic foot ulcers (DFUs).
- Conditions
- Diabetic Foot Ulcer, Diabetic Foot, Foot Ulcer Due to Type 2 Diabetes Mellitus, Foot Ulcer, Diabetic
- Trial name
- CAMPAIGN (NCT06600724)
- Testing
- Standard of Care, EPIEFFECT, EPIXPRESS
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- MiMedx Group, Inc.
Diabetic Foot Ulcer, Leg Ulcer
Open Label Single Arm Proof of Concept Trial to Evaluate the Efficacy and Safety of Cytori Celution System in Diabetic Leg Ulcers
To evaluate the efficacy and safety of Cytori Celution System in Hungarian patients with diabetic leg ulcers.
- Conditions
- Diabetic Foot Ulcer, Leg Ulcer, Autologous Adipose Stromal Vascular Fraction, Mesenchymal Stem Cells
- Trial name
- NCT05274295
- Testing
- Diabetic leg ulcer treatment with adipous SVF
- Where
- Hungary
- Volunteers
- 5 people
- Sponsor
- Szeged University
Pressure Ulcer
Adipose-Derived Stromal Cells (ASC's) for Pressure Ulcers
This pilot study of 12 patients will test the safety and efficacy of applying autologous, adipose-derived stromal cells (ASCs), uncultured, on a Stage III or IV pressure ulcer or diabetic foot ulcers.
- Trial name
- NCT02375802
- Testing
- Adipose-derived stromal cells
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Mayo Clinic
Endometriosis Related Pain, Overactive Bladder
A Trial to Learn How a New Liquid Form of BAY1817080 is Tolerated and Taken up by the Body of Healthy Male Participants (Part A). By Labeling BAY1817080 With a Radioactive Substance (Carbon 14) Researchers Want to Learn How the Study Drug is Processed and Excreted by the Body After Dosing (Part B)
Researchers are looking for a new way to treat people suffering either from a condition where the bladder is unable to hold urine normally (overactive bladder), or a condition in which tissue similar to the tissue that normally…
- Conditions
- Endometriosis Related Pain, Overactive Bladder, Diabetic Neuropathic Pain, Refractory or Unexplained Chronic Cough
- Trial name
- NCT04487431
- Testing
- BAY1817080, [14C]BAY1817080
- Where
- Netherlands
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Bayer
Diabetic Foot Ulcer
Treatment of Chronic Wounds in Diabetic Foot Syndrome With Allogeneic Adipose Derived Mesenchymal Stem Cells
The aim of this study is to investigate efficiency of applying of adipose-derived mesenchymal stem cells (ADSC) in treatment of chronic wounds in diabetic foot syndrome.
- Trial name
- 1ABC (NCT03865394)
- Testing
- Application of allogeneic ADSC stem cells in fibrin gel, Standard care in diabetic foot ulcer
- Where
- Poland
- Volunteers
- 46 people
- Sponsor
- Medical University of Warsaw
Diabetes Mellitus, Type 2
Allogeneic Mesenchymal Human Stem Cells Infusion Therapy for Endothelial DySfunctiOn in Diabetic Subjects
This is a 16 subject trial to demonstrate the safety of allogeneic hMSCs administered via infusion therapy for diabetic subjects with endothelial dysfunction.
- Trial name
- ACESO (NCT02886884)
- Testing
- 20 million Allogeneic Mesenchymal Human Stem Cells, 100 million Allogeneic Mesenchymal Human Stem Cells
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Joshua M Hare
Eye Diseases, Retinitis Pigmentosa
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Exosomes for NAION
This trial will study the safety and efficacy of intranasal delivery of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cell exosomes for the treatment of non-arteritic ischemic optic neuropathy
- Conditions
- Eye Diseases, Retinitis Pigmentosa, Diabetic Retinopathy, Macular Degeneration
- Trial name
- NCT05147701
- Testing
- cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cell exosomes
- Where
- 2 sites in United States, Greece
- Volunteers
- 20 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Erectile Dysfunction
Bone Marrow Mesenchymal Stem Cells in Erectile Dysfunction (ED)
Recovery of erectile function using bone marrow mesenchymal stem cells (MSCs) after in vitro expansion under restricted culturing conditions.
- Trial name
- NCT02945462
- Testing
- autologous mesenchymal stem cells
- Volunteers
- 4 people
- Sponsor
- University of Jordan
Diabetic Peripheral Neuropathy
Effect Of Mesenchymal Stem Cells Transfusion on the Diabetic Peripheral Neuropathy Patients .
A debilitating consequence of diabetes mellitus (DM) is neuropathy which globally affects between 20 -30% of diabetic patients and up to 50% in other studies.
- Trial name
- NCT02387749
- Testing
- mesenchymal stem cells
- Volunteers
- 10 people
- Sponsor
- Cairo University
Age-related Macular Degeneration, Retinal Vein Occlusion
Computer-based Tutorial and Automated Speech Recognition for Intravitreal Drug Injections
Evaluation if a computer-based tutorial ("MacInfo" tool) improves the patients' knowledge about intravitreal drug injections, associated risks, and the underlying diseases of treatment-naive patients.
- Conditions
- Age-related Macular Degeneration, Retinal Vein Occlusion, Diabetic Macular Edema
- Trial name
- NCT04142164
- Testing
- MacInfo presentation
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Critical Limb Ischemia (CLI)
Clinical Trial I/II Opened, Randomized and Controlled for the Study of the Use of Stem Cells Therapy in Insulinized Diabetic Patients Type 2 With Critical Ischemia in Lower Limbs (CLI): Study of the Needs of Insulin
To study the effect of the stem cells therapy autologous mononuclear from the bone marrow, autologous progenitor endothelial CD133 cells from the bone marrow and autologous mesenchymal stem cells from adipose tissue on the…
- Trial name
- NCT02287974
- Testing
- Stem cell infusion
- Where
- 2 sites in Spain
- Volunteers
- 20 people
- Sponsor
- Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud
Diabetic Peripheral Neuropathy (DPN)
A Randomized Controlled Trial on the Efficacy and Safety of Umbilical Cord Mesenchymal Stem Cell Therapy in Subjects With Moderate to Severe Diabetic Peripheral Neuropathy
This clinical trial aims to evaluate the efficacy and safety of human umbilical cord mesenchymal stem cell (hUC-MSC) injection in the treatment of adults with moderate to severe diabetic peripheral neuropathy.
- Trial name
- RELEASE-DPN (NCT07183761)
- Testing
- Experimental Group, Conventional therapy group
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Min Long
Diabetes Mellitus, Type 2
Effect of Vitamin C, D and Zinc Supplementation on the Immune and Inflammatory Process in Type 2 Diabetic Subjects
Type 2 Diabetes Mellitus According to the World Health Organization (WHO), there are more than 346 million individuals with diabetes, of which 90% are type 2.
- Trial name
- NCT03734445
- Testing
- Vitamin Supplement
- Volunteers
- 120 people
- Sponsor
- Universidad Autonoma del Estado de Mexico
Diabetic Foot Ulcer
Evaluation of the Safety and Efficacy of Live ASCs in the Treatment of Diabetic Foot Syndrome.
The goal of this study is to evaluate the safety and efficacy of an advanced therapy medicinal product containing live allogeneic adipose-derived mesenchymal stem cells (ADSC/ASC) for the treatment of diabetic foot ulcers in a…
- Trial name
- FOOTCELL (NCT06843122)
- Testing
- Allogeneic ADSC/ASC (alloADSC-DFU-RL)
- Where
- Poland
- Volunteers
- 105 people
- Sponsor
- Medical University of Warsaw
Diabetic Nephropathies
Use of Wharton Jelly in Diabetic Nephropathy
Wharton Jelly derived Mesenchymal stem cells will be injected in the renal parenchyma of patients with Diabetic Nephropathy
- Trial name
- NCT03288571
- Testing
- Wharton Jelly Mesenchymal stem cells
- Volunteers
- 20 people
- Sponsor
- Sophia Al-Adwan
Type 1 Diabetes Mellitus
MSC Administration for the Management of Type 1 Diabetic Patients
The purpose of this study is to evaluate whether the administration of multipotent stromal cell also referred as to mesenchymal stem cells (MSCs), modified Type 1 Diabetes progression.
- Trial name
- DMT1-MSC (NCT02893306)
- Testing
- MSCs
- Where
- Chile
- Volunteers
- 10 people
- Sponsor
- Universidad del Desarrollo
Non-exudative Age-related Macular Degeneration, Diabetic Retinopathy
Clinical Trial of Autologous Intravitreal Bone-marrow CD34+ Stem Cells for Retinopathy
This pilot study is to determine whether it would be safe and feasible to inject CD34+ stem cells from bone marrow into the eye as treatment for patients who are irreversibly blind from various retinal conditions.
- Conditions
- Non-exudative Age-related Macular Degeneration, Diabetic Retinopathy, Retina Vein Occlusion, Retinitis Pigmentosa
- Trial name
- NCT01736059
- Testing
- CD34+ bone marrow stem cells intravitreal
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, Davis