Clinical trials: thyroid
Iodine Excess in Pregnancy, Selenium Excess in Pregnancy
The Correlation Between Iodine and Selenium Status in Pregnancy and Risk of Thyroid Disease
Two hundred and ninety pregnant women with gestational age less than 20 weeks will be recruited in this study. Selenium and iodine conditions, and risk of thyroid disease will be monitored until termination of pregnancy, with…
- Conditions
- Iodine Excess in Pregnancy, Selenium Excess in Pregnancy, Iodine Deficiency in Pregnancy, Selenium Deficiency in Pregnancy
- Trial name
- NCT03761602
- Testing
- Not applicable (for observational studies)
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Rongrong Li
Obesity, Colon Cancer
Proteomic Analysis of Patients Undergoing Bariatric Surgery
The expression of proteins in the blood of obese individuals is different from the expression of proteins in healthy individuals, and is also different in individuals after bariatric surgery.
- Conditions
- Obesity, Colon Cancer, Thyroid Cancer, Esophageal Cancer
- Trial name
- NCT06787807
- Testing
- bariatric surgery
- Where
- Brazil
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Thyroid
The Efficacy and Safety of Thunderbeat in Thyroid Surgery
The aim of this study is to compare the results of total thyroidectomy using the Thunderbeat device to that with the harmonic scalpel.
- Trial name
- Thunderbeat (NCT02304172)
- Testing
- Thunderbeat (Group A), Harmonic (Group B)
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Healthy
BE of Euthyrox® Tablets (Merck Nantong Versus Merck Darmstadt Sites)
The purpose of this study is to demonstrate bioequivalence (BE) between Euthyrox® tablets manufactured at Merck Nantong (Test Euthyrox) versus the tablets manufactured at Merck Darmstadt (Reference Euthyrox).
- Trial name
- NCT05174000
- Testing
- Test Euthyrox®, Reference Euthyrox®
- Where
- China
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Thyroid Nodule
Role of TIRADS and Bethesda Scoring Systems in Management of Thyroid Nodules
role of TIRADS and Bethesda scoring system in management of thyroid nodules as these methods are ultrasound clasification that helps increase the diagnostic effectiveness of thyroid nodules and reduces the use of preopeative FNA…
- Trial name
- NCT06417463
- Testing
- thyroidectomy opeartion
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sohag University
Thyroid Cancer
Thyroid Cancer Among Chornobyl Clean-up Workers in Ukraine: Pilot Study
Background: The Ukrainian Research Center for Radiation Medicine and the U.S. National Institutes of Health have been studying cancer risks and outcomes in individuals who participated in the decontamination clean-up process…
- Trial name
- NCT01265381
- Where
- Ukraine
- Volunteers
- 673 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Vitamin B12 Deficiency
Autoantibodies to Gastric Parietal Cells in Rheumatoid Arthritis Patients
A review of the literature reveals that very few studies have assessed the potential co-existence of vitamin B12 deficiency due to gastric parietal cell autoantibodies. While Segal et al.
- Trial name
- NCT01876329
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Keesler Air Force Base Medical Center
Thyroid Nodule, Thyroid Cancer
The Safety and Feasibility of Radiofrequency Ablation to Treat Low-risk Thyroid Cancer
The goal of this clinical trial is to test radiofrequency ablation (RFA) in thyroid cancers ≤2 cm in diameter. The main question it aims to answer is: What is the feasibility of RFA use for low-risk thyroid cancers (≤2 cm)?…
- Trial name
- NCT06929650
- Testing
- Radiofrequency ablation
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Pregnancy Related, Thyroid Stimulating; Hormone, C
Correlation Between Levothyroxine and Blood Th17/Treg in Pregnant Women With Normal-high TSH and Positive TPOAb
The purpose of this clinical trial is to understand the impact of different doses of levothyroxine on the immune inflammatory response in pregnant women with normal-high TSH and positive TPOAb in the first half of pregnancy.
- Trial name
- NCT06527859
- Testing
- Levothyroxin
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Third Affiliated Hospital of Zhengzhou University
Diabetes Mellitus, Hypertension
Evidence-based Laboratory Test Order Sets in Primary Care
Cluster randomised controlled trial to evaluate what the effect is of evidence-based order sets aimed at five indications on the appropriateness of laboratory test ordering in primary care.
- Conditions
- Diabetes Mellitus, Hypertension, Cardiovascular Diseases, Fatigue
- Trial name
- NCT02950142
- Testing
- CPOE with order sets for lab testing, CPOE without order sets for lab testing
- Where
- Belgium
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Sub-clinical Hypothyroidism, Hypothyroidism
Validation of a New TSH Test
The aim of this research project, which is realised with the partnership of the enterprise Siamed'Xpress (Marseille), is to validate a new TSH diagnostic test in vitro, to allow an earlier screening of hypothyroidism.
- Conditions
- Sub-clinical Hypothyroidism, Hypothyroidism, Euthyroidism
- Trial name
- NCT01997554
- Testing
- Blood sample
- Where
- 2 sites in France
- Volunteers
- 1,654 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Thyroid Dysfunction
Serum Thyroid Function After Iodinated Contrast Administration
This study investigated the changes in serum thyroid function and urinary iodine levels before and after the use of iodinated contrast to analyze the prevalence of thyroid dysfunction in the Chinese euthyroid adults after using…
- Trial name
- NCT05786846
- Testing
- Iodinated contrast agents
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Thyroid Cancer
Efficacy of Subfascial Approach in Thyroidectomy to Quality of Life in Thyroid Disease Patients
Subfascial approach method in thyroidectomy maybe result in better quality of life than conventional approach method in thyroid disease patients
- Trial name
- NCT01616316
- Testing
- subfascial flap, subplatysmal flap
- Where
- South Korea
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Thyroid Cancer, Breast Cancer
Dexamethasone Reduces Postoperative Emesis by Decreasing PGF2α and LTC4 Levels
Hypothesis: Dexamethasone reduces postoperative emesis in thyroidectomy and mastectomy patients.
- Trial name
- NCT01811199
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Marmara University
Congenital Hypothyroidism
Infants With Primary Congenital Hypothyroidism and Development
A review of the literature has focused primarily on the cognitive and motor development of children with congenital hypothyroidism, but no studies on sensory processing skills have been found.
- Trial name
- NCT07280104
- Testing
- neurological status, sensory processing functions, Motor development
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Fatigue, Hypothyroidism
The Effect of Aroma on Fatigue Scores Among Women With Hypothyroidism
This study evaluates the effects of an inhaled blend of essential oils on fatigue scores among women who have hypothyroidism. Half of the participants will receive an essential oil blend to inhale daily for two weeks while the…
- Trial name
- NCT03465176
- Testing
- Aromatherapy Blend
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nutraceuticals Research Institute
Computerized Cytomorphometry
Diagnostic and Prognostic Significance of Computerized Cytologic Morphometry of the Thyroid Neoplasm
The prevalence of thyroid nodule is worldwide high. About 40% of normal population has thyroid nodules and about 5% are malignancy.
- Trial name
- NCT03105648
- Testing
- computerized cytomorphometry
- Where
- Taiwan
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Hypothyroidism
Bioequivalence of Two Levothyroxine Tablet Formulations in Healthy Indian Volunteers
GSK markets a drug called levothyroxine or T4 that is used to treat patients with hypothyroidism. Till date, the active drug substance or active pharmaceutical ingredient (API) for levothyroxine tablets marketed in India has been…
- Trial name
- NCT01536678
- Testing
- Levothyroxine
- Where
- India
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Recurrent Early Pregnancy Loss, Thyroid Diseases
Thyroxine Therapy for Recurrent Pregnancy Loss in Hypothyroid Women
The goal of this clinical trial is to investigate the influence of thyroxine supplementation on pregnancy outcomes in women with varying levels of Thyroid-Stimulating Hormone (TSH), who have experienced recurrent pregnancy loss…
- Trial name
- NCT06036576
- Testing
- Levothyroxine Pill
- Where
- Iraq
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Al-Kindy College of Medicine
Thyroid Cancer
Myeloid Cell Reprogramming in Thyroid Carcinoma
This study investigates the reprogramming of myeloid cells in patients with thyroid carcinoma. The investigators hypothesize that tumor-derived factors change the function of myeloid cells (peripheral blood and bone…
- Trial name
- NCT03397238
- Where
- Netherlands
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center