Clinical trials: v
Nipah Virus Infection
Safety and Immunogenicity of a Nipah Virus Vaccine
A first-in-human, phase 1 trial is to be conducted in a healthy adult population in the US to assess the safety and immunogenicity of three ascending Nipah vaccine (HeV-sG-V; Hendra virus soluble glycoprotein vaccine) dosages.
- Trial name
- NCT04199169
- Testing
- HeV-sG-V
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Auro Vaccines LLC
SARS-CoV2 Infection, Covid19
Pregnant and Lactating Individuals & Newborns COVID-19 Vaccination Prospective Cohort Study
The PLAN-V Study is an Ontario-based prospective, longitudinal study that will consist of extensive biosampling and detailed data collection from pregnant women/individuals, who have received the COVID-19 vaccine during their…
- Conditions
- SARS-CoV2 Infection, Covid19, Vaccine Reaction, Pregnancy Related
- Trial name
- PLAN-V (NCT05115617)
- Where
- 7 sites in Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Pharmacokinetics
Fasted Bioequivalence Study of 2 Olanzapine Film-coated Tablets, 5 mg, in Healthy, Adult Male and Female Subjects.
This study was designed to assess the bioequivalence of Olanzapine tablets of two different manufacturers and to investigate the safety and tolerability of Olanzapine tablets of two different manufacturers.
- Trial name
- NCT05123976
- Testing
- Olanzapine film-coated tablets 5 mg (JSC Farmak, Ukraine), Zyprexa® coated tablets 5 mg (Eli Lilly, Nederland B V)
- Where
- Czechia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Joint Stock Company "Farmak"
Metabolism, Inborn Errors, Lipid Metabolism, Inborn Errors
Fat and Sugar Metabolism During Exercise in Patients With Metabolic Myopathy
This study aims to characterize the pathophysiological mechanisms of 21 different metabolic myopathies. The study will focus on exercise capacity and the metabolic derangement during exercise.
- Conditions
- Metabolism, Inborn Errors, Lipid Metabolism, Inborn Errors, Carbohydrate Metabolism, Inborn Errors, Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency
- Trial name
- NCT02635269
- Testing
- Sugar
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Diarrhea, Cholera
PK Study of iOWH032 in Adult Male/Female Healthy Volunteers & Adult Males With Cholera
This study will assess if the pharmacokinetics, safety and tolerability of iOWH032 are grossly different in 1) Bangladeshi healthy population and 2) Bangladeshi cholera patients. This is not a hypothesis-driven research study.
- Trial name
- PISCES (NCT01823939)
- Testing
- iOWH032
- Where
- Bangladesh
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- PATH
Dietary Habits, Dietary Modification
Fresh to You: Multilevel Approaches in Low Income Housing to Increase F&V Intake
Live Well, Viva Bien (LWVB) is an NCI-funded, cluster randomized controlled trial (RCT) that was conducted in 15 subsidized housing complexes to evaluate the efficacy of a multicomponent intervention comprised of a year-round…
- Trial name
- LWVB (NCT02669472)
- Testing
- Environmental Intervention, Educational Intervention, Control
- Volunteers
- 1,598 people, healthy volunteers welcome
- Sponsor
- Brown University
Pain, Symptomatic Irreversible Pulpitis
The Effectiveness of Single Antibiotic Paste Nitrofurantoin Versus Double Antibiotic Paste
In our study, we used nitrofurantoin as a root canal medication in patients suffering from symptomatic irreversible pulpitis in alleviating pain compared with double antibiotic paste.
- Trial name
- NCT05600023
- Testing
- Nitrofurantoin, Double Antibiotic
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine
Vascular Lesion, Pigmented Lesions
Evaluation of Safety and Efficacy of IPL Presets for Cutaneous Lesions
Single-center, Prospective, Open-Label with Before-After Study Design. Each subject will receive up to three (3) consecutive treatments at 1-month interval.
- Trial name
- NCT05630690
- Testing
- IPL with smart diagnostic handpiece
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lumenis Be Ltd.
Postoperative Nausea and Vomiting
Evaluation of the Effect of Two Types of Fluid in the Recovery From Anaesthesia. Voluven 6% v Hartmanns
Avoiding nausea and vomiting is one of the most important for patient comfort and satisfaction, and preventing unplanned overnight stays in hospital following surgery.
- Trial name
- NCT01122459
- Testing
- fluid administration
- Where
- Ireland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Rotunda Hospital
Diabetic Retinopathy
PST/Laser v. Laser Alone for CSME
Prospective randomized clinical trial comparing Laser Alone v. Laser and posterior sub-tenon injection of triamcinolone acetonide for primary and refractory clinically significant macular edema.
- Trial name
- NCT00229918
- Testing
- triamcinolone acetonide
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Edward Hines Jr. VA Hospital
Hypotension, Anesthesia
Methohexital v Propofol as General Anesthetic in Patients on ACEIs or ARBs
Patient undergoing general anesthesia in elective surgery will be assigned to receive either methohexital or propofol general anesthesia.
- Trial name
- NCT02624050
- Testing
- Methohexital, Propofol
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Efficiency and Safey of Radial Artery Cannulation
Novel Local Infiltration Anesthesia for Radial Artery Cannulation.
This clinical trial aims to compare the pain scores and cannulation success rates of conventional, bar-shaped, and V-shaped local infiltration anesthesia in participants' radial artery cannulation.
- Trial name
- NCT05735132
- Testing
- Conventional Line-blocking, Bar-blocking, V-blocking
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- First People's Hospital of Chenzhou
Anesthesia, ERAS
Impact of General Anesthesia v/s Spinal Anesthesia on ERAS Parameters in Intestinal Stoma Reversal
Randomized, Interventional ,Open labeled, Parallel Assignment and Superiority trial.
- Conditions
- Anesthesia, ERAS, Surgical Stomas, Ileostomy - Stoma
- Trial name
- SPIGERAS (NCT06226753)
- Testing
- Type of anaesthesia used
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
White Spot Lesion of Tooth
Combined Application of Diode Laser and Different Remineralizing Agents on White Spot Lesions
Dental caries is a very common condition, and although it has become less common, it still represents a serious public health risk.
- Trial name
- Whitespot (NCT05871619)
- Testing
- Remin Pro, X Pur Remin, Fluoride varnish
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Total Hip Arthroplasty (THA), Impaction
Automated V Manual Impactor Study
This study investigates the use of an automated impactor device in total hip arthroplasty versus manual malleting method and the physiological strain on the surgeon.
- Conditions
- Total Hip Arthroplasty (THA), Impaction, Physiological Strain
- Trial name
- NCT06903767
- Testing
- Automated Impaction (HAMMR), Manual Malleting
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Sexual Function Scores, Postoperative Recovery
V-NOTES Versus Laparoscopy for Sterilization and Sexual Function
The goal of this randomized clinical trial is to compare two minimally invasive surgical approaches, transvaginal natural orifice transluminal endoscopic surgery (V-NOTES) and conventional laparoscopy, in women undergoing…
- Trial name
- VNOTES-LS-FSFI (NCT07637201)
- Testing
- V-NOTES Bilateral Tubal Ligation or Salpingectomy, Laparoscopic Bilateral Tubal Ligation or Salpingectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Tepecik Training and Research Hospital
Restoration of Carious Class v Anterior Teeth
Aesthetic Performance of Two Injectable Resin Composites in Class V Cavities: A Randomized Clinical Trial
Using bioactive injectable resin composite in anterior class v carious lesions can provide better aesthetic outcome and marginal integrity by releasing multiple ions, including fluoride.
- Trial name
- NCT06950762
- Testing
- Giomer based injectable composite, Universal injectable resin composite
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Scarring, Skin Aging
Open-label, Prospective, Multicenter Study to Evaluate the Cutera Excel V™ Laser and a Micro-Lens Array Attachment
Open-label, Prospective, Study to Evaluate the Cutera excel V laser at 532 nm in a low fluence, high repetition rate mode and the Micro-Lens Array attachment used with excel V laser at 1064 nm and 532 nm for the improvement of…
- Trial name
- NCT03424148
- Testing
- Excel V™ Laser & Micro-Lens Array Attach
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Class V Dental Caries
Assessment of Alkasite Restorative Material Versus Resin Modified Glass Ionomer in Class V Cavities: A Clinical Trial
This study will be conducted to evaluate the clinical assessment of an alkasite based resin composite restorative material compared to resin modified glass ionomer based restorative material in class V cavities of anterior teeth…
- Trial name
- NCT06673888
- Testing
- Resin modified glass ionomer, alkasite based restorative material
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Influenza
A Re-licensing Study to Assess the Efficacy of Inflexal V Formulated With WHO Recommended 2008/2009 Influenza Virus Strains for the Northern Hemisphere
A study to assess whether the Northern Hemisphere 2008/2009 season influenza vaccine Inflexal V fulfills the EMEA requirements for re-registration of influenza vaccines
- Trial name
- NCT01303510
- Testing
- Inflexal V
- Where
- Switzerland
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Crucell Holland BV