Clinical trials: in Croatia
Multisystem Inflammatory Syndrome in Children (MIS-C)
Quality of Life in Children After Multisystem Inflammatory Syndrome in Children
The aim of this observational study is to assess whether Multisystem Inflammatory Syndrome (MIS-C) in children affects their quality of life.
- Trial name
- MIS-C (NCT07126028)
- Where
- Croatia
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Kristina Lah Tomulić
Healthy Volunteers, Muscle Strength
Acute Effects of Stretching, Kinesio Taping, Cold Water Immersion and Foam Rolling on Wrist Strength and Precise Force and Position Control
Static stretching, dynamic stretching, elastic (Kinesio) taping, brief cold water immersion and foam rolling are used daily in sport and rehabilitation to prepare the forearm and hand, but it is not known whether, immediately…
- Conditions
- Healthy Volunteers, Muscle Strength, Motor Control
- Trial name
- NCT07886736
- Testing
- Static stretching, Assisted dynamic stretching, Kinesio taping
- Where
- Croatia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Grgur Kovačić
Compliance, Periodontitis
Association Between Periodontal Status and the Interrupted Supportive Periodontal Therapy During the COVID-19 Pandemic
This cross-sectional observational study compared the clinical periodontal status and oral health-related quality of life between patients who continued regular supportive periodontal therapy (SPT) visits during the COVID-19…
- Conditions
- Compliance, Periodontitis, Periodontal Therapy
- Trial name
- NCT07866664
- Testing
- Prolonged interruption of supportive periodontal therapy (≥24 months)
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Alveolar Bone Loss, Tooth Loss / Rehabilitation
Bone and Soft Tissue Healing After Socket Preservation With NOVAMag or Permamem Membranes
After tooth extraction, the surrounding bone and soft tissue may undergo dimensional reduction. Socket preservation involves placement of a bone graft into the extraction socket and coverage with a membrane to support healing…
- Conditions
- Alveolar Bone Loss, Tooth Loss / Rehabilitation, Alveolar Bone Grafting, Socket Preservation
- Trial name
- NCT07856693
- Testing
- NOVAMag Membrane, permamem Membrane, Alveolar Socket Preservation With an Allogeneic Bone Graft
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Knee Osteoarthritis (Kellgren-Lawrence Grade 1-3), Knee Osteoarthritis
Comparison of Leucocyte-rich PRP and Leucocyte-poor PRP in Treating Mild to Moderate Knee Osteoarthritis
The purpose of this study is to show that there is no difference in patient clinical scores when patients with knee pain are treated with joint application of high dose white blood cell PRP (platelet-rich plasma) and low dose…
- Conditions
- Knee Osteoarthritis (Kellgren-Lawrence Grade 1-3), Knee Osteoarthritis, PRP, Platelet-rich Plasma (PRP)
- Trial name
- NCT07857954
- Testing
- Intra-articular platelet-rich plasma
- Where
- Croatia
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- St. Catherine Specialty Hospital
Healthy Volunteers
Skin Barrier Function in Women Using UV Nail Lamps
The goal of this observational study is to compare objective parameters of skin barrier function between healthy adult women who regularly use UV lamps during nail treatments and women who do not use UV lamps.
- Trial name
- NCT07700186
- Where
- Croatia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Crohn Disease
Decoding Personalized Nutritional, Microbiome and Host Patterns Impacting Clinical and Prognostic Features in Crohn's Disease
This is a three-arm, non-interventional observational study designed to investigate the relationship between Crohn's disease (CD), the microbiome, and diet in children.
- Trial name
- NCT04283864
- Testing
- endoscopy examination
- Where
- 8 sites in Canada, Croatia and 5 more
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Weizmann Institute of Science
Ulcerative Colitis (UC)
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
The Phase 1 study described herein will evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of XmAb942 in healthy volunteers (Parts A and B).
- Trial name
- NCT06619990
- Testing
- XmAb942
- Where
- 98 sites in United States, Argentina and 13 more
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Xencor, Inc.
Wisdom Tooth Removal, Dental Anesthesia
Effect of Subperiosteal Ropivacaine After Third Molar Extraction
This study examined whether an additional injection of the long-acting local anesthetic ropivacaine at the surgical site could reduce pain and improve recovery after removal of lower wisdom teeth.
- Conditions
- Wisdom Tooth Removal, Dental Anesthesia, Ropivacaine
- Trial name
- NCT07844824
- Testing
- Ropivacaine 0.75%, Saline (0.9% NaCl)
- Where
- Croatia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Irritant Contact Dermatitis
Glycyrrhetinic Acid and Acute Irritant Dermatitis
Irritant dermatitis is one of the most common inflammatory skin disorders, caused by exposure to external substances that induce inflammation and immune activation.
- Trial name
- NCT07286487
- Testing
- SLS induced irritation, No Treatment, Low Dose Glycyrrhetinic Acid Formulation
- Where
- Croatia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Skin Barrier Function, Skin Hydration
Study of a Peptide Cream's Effect on the Facial Skin Barrier Using a Side-by-Side Comparison
The goal of this clinical trial is to evaluate whether a topical face cream containing the peptide Acetyl Hexapeptide-37 improves skin hydration and strengthens the skin barrier compared to a placebo cream in healthy adult…
- Conditions
- Skin Barrier Function, Skin Hydration, Topical Peptide Effects on Facial Skin Barrier Function
- Trial name
- NCT07548424
- Testing
- Acetyl Hexapeptide-37 Cream
- Where
- Croatia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Metabolic Syndrome, Inactivity/Low Levels of Exercise
Impact of Lifestyle on Health Maintenance: A Randomized Controlled Trial
This study aims to evaluate the impact of public health interventions on changes in healthy lifestyle habits over time and their subsequent effects on health outcomes.
- Conditions
- Metabolic Syndrome, Inactivity/Low Levels of Exercise, Unhealthy Diet, Unhealthy Alcohol Use
- Trial name
- LifeHealth-RCT (NCT07314957)
- Testing
- Intervention of physical activity, Mediterranean Diet Education, Behavioral: Stress-Resilience Training
- Where
- Croatia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zadar
Hypertension, Endothelial Function
Endothelial Extracellular Vesicles as Biomarkers of Endothelial Activation in Adults With Newly Diagnosed Hypertension
Hypertension is associated with endothelial dysfunction, an early event in the development of cardiovascular disease. Endothelial extracellular vesicles (EEVs) have emerged as promising biomarkers of endothelial activation and…
- Trial name
- HYPER-endoEV-a (NCT07728630)
- Where
- Croatia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Pediatric Hypertension, Primary Hypertension
Endothelial Extracellular Vesicles as Biomarkers of Endothelial Activation in Children With Newly Diagnosed Hypertension
Childhood hypertension is associated with early endothelial dysfunction and an increased risk of future cardiovascular disease. Endothelial extracellular vesicles (EEVs) have emerged as promising biomarkers of endothelial…
- Conditions
- Pediatric Hypertension, Primary Hypertension, Endothelial Dysfunction
- Trial name
- HYPER-endoEV-c (NCT07728643)
- Where
- Croatia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Skin Barrier Disruption and Recovery
Helichrysum Italicum Extract in Irritant Contact Dermatitis
The goal of this clinical trial is to evaluate the efficacy and safety of a topical cream containing Immortelle (Helichrysum italicum) extract in promoting skin barrier recovery and reducing signs of irritant contact dermatitis…
- Trial name
- NCT07676253
- Testing
- Helichrysum italicum Extract Cream
- Where
- Croatia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Perimenopause, Menopause
CARAMEL Observational Study
CARAMEL is a project funded by the European Commission under the Horizon Europe programme. Its aim is to develop a personalized prevention approach based on state-of-the-art artificial intelligence models for cardiovascular risk…
- Conditions
- Perimenopause, Menopause, Cardiovascular (CV) Risk, Women (Between 30 to 60 Years Old)
- Trial name
- CARAMEL-OS (NCT07695376)
- Where
- 6 sites in Colombia, Croatia and 3 more
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Biogipuzkoa Health Research Institute
Hypertension, Cardiovascular Risk Factors
Community Blood Pressure Screening and Cardiovascular Risk Assessment in Croatia
This is a prospective, observational, non-interventional study conducted during community-based public health blood pressure screening campaigns in Croatia.
- Trial name
- BPSCREEN-CRO (NCT07670741)
- Testing
- Blood pressure measurement and questionnaire-based data collection
- Where
- Croatia
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Dr. Josip Benčević General Hospital
Parkinson Disease, Multiple System Atrophy
Research of Biomarkers in Parkinson Disease
The main goal of the GENEPARK consortium is to employ innovative haemogenomic approaches to determine gene expression profiles specific for genetic and idiopathic Parkinson's disease (PD) patients.
- Conditions
- Parkinson Disease, Multiple System Atrophy, Progressive Supranuclear Palsy, Huntington Disease
- Trial name
- Genepark (NCT00465790)
- Where
- 5 sites in Croatia, France and 2 more
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Skin Barrier Disruption and Recovery
Evaluation of a Peptide Cream on the Forearm Skin Recovery of Healthy Volunteers
The goal of this clinical trial is to evaluate the efficacy of a topical peptide-based formulation containing Acetyl Hexapeptide-37 in promoting skin barrier recovery after controlled disruption in healthy adult participants.
- Trial name
- NCT07614698
- Testing
- Acetyl Hexapeptide-37
- Where
- Croatia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Edentulism, Edentulism Complete
Masticatory Efficiency, Bite Force, and Patient-Reported Outcomes in Patients Rehabilitated With Complete and Partial Dentures Supported by Teeth, Mini-Implants, or Conventional Implants
This study aims to evaluate masticatory efficiency, bite force, and patient-reported outcomes in edentulous and partially edentulous patients rehabilitated with different removable prosthodontic treatment modalities.
- Conditions
- Edentulism, Edentulism Complete, Partial Edentulism, Complete Dentures
- Trial name
- IMPROSTREHAB (NCT07639112)
- Where
- 2 sites in Croatia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Zagreb