Clinical trials: Best Practice
Cardiovascular Risk Reduction of Having a Coronary Event
A Novel Approach to Cardiovascular Health by Optimizing Risk Management (ANCHOR)
Study Purpose and Design The goal of this study is to improve CVD risk in a primary care adult population, with the following primary objectives 1.
- Trial name
- ANCHOR (NCT01620996)
- Testing
- Minimal Intervention, Motivational Interviewing, Motivational Enhancement
- Where
- Canada
- Volunteers
- 1,708 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Burnout, Professional
Coaching for Advanced Practice Providers
This study aims to determine if online coaching is feasible in advanced practice providers (APP) and can impact burnout. The study will recruit APPs from Children's Healthcare of Atlanta (CHOA), Emory, Colorado University (CU)…
- Trial name
- NCT05938556
- Testing
- hybrid asynchronous-synchronous group coaching program, treatment as usual group (TAU)
- Where
- 4 sites in United States
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- Emory University
Traumatic Brain Injury
Heart Rate Variability Biofeedback Following Traumatic Brain Injury
Individuals with mild traumatic brain injury will be randomly assigned to an active heart rate variability biofeedback condition and a sham condition.
- Trial name
- NCT05913505
- Testing
- OSC+, OSC-
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Brigham Young University
Immunization, DTaP Vaccine
Comparison of Immunization Quality Improvement Dissemination Study
Dissemination research examines the processes and factors that lead to widespread use of evidence-based interventions. There are several theories on how to best minimize the perceived and actual burdens on practitioners…
- Conditions
- Immunization, DTaP Vaccine, Hepatitis B Vaccine, MMR Vaccine
- Trial name
- CIzQIDS (NCT02432430)
- Testing
- QI support to improve DTP/Hep B/MMR/Var/PCV/Hib/IPV coverage, Incentives to improve DTP/HepB/MMR/Var/PCV/Hib/IPV coverage
- Volunteers
- 2,186 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Ecological Momentary Assessment Best Practices
Exemplar: Determining the Best Practices for EMA Studies
Ecological momentary assessment (EMA) is a measurement methodology that utilizes the repeated collection of real-time data on participants' behavior and experience in their natural environment.
- Trial name
- Exemplar (NCT05194228)
- Testing
- Ecologial Momentary Assessment settings
- Where
- United States
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Healthy Subject
HPV Vaccine Intervention for Young Sexual Minority Men
This phase III trial studies how well the Outsmart HPV intervention works in increasing HPV vaccine initiation and completion among young individuals who report having a history of same-sex partners, being sexually attracted to…
- Trial name
- NCT04032106
- Testing
- Best Practice, Informational Intervention, Questionnaire Administration
- Where
- 2 sites in United States
- Volunteers
- 1,227 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Hip Osteoarthritis, Knee Osteoarthritis
Determining the Impact of a Physiotherapist-Led Primary Care Model for Hip and Knee Pain - A Pilot Trial
This is a pilot cluster randomized controlled trial to to evaluate the individual and health system impacts of implementing a new physiotherapist-led primary care model for hip and knee pain in Canada.
- Trial name
- NCT05736133
- Testing
- Physiotherapist-led primary care model for hip and knee pain, Usual physician-led primary care model for hip and knee pain
- Where
- Canada
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Jordan Miller, PT, PhD
Malnutrition, Child, Enteropathy
Study of Environmental Enteropathy and Malnutrition in Pakistan
Environmental Enteropathy (EE) is an acquired sub-clinical inflammatory gut condition in which alterations in intestinal structure, function, and local and systemic immune activation lead to impaired vaccine responses, decreased…
- Conditions
- Malnutrition, Child, Enteropathy, Vaccine Response Impaired, Stunting
- Trial name
- SEEM (NCT03588013)
- Testing
- Nutritional education, Ready to Use Therapeutic Food, Upper gastrointestinal endoscopy with biopsy
- Where
- Pakistan
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Breast Carcinoma
Mobile Health Patient Navigation for the Improvement of Screening and the Early Detection of Breast Cancer in Women Accessing Primary Care Clinics in Kenya
This clinical trial develops and studies how well mobile health (m-Health) patient navigation (PN) strategies work to improve screening and the early detection of breast cancer in women accessing primary care clinics in Kenya.
- Trial name
- NCT07764796
- Testing
- Best Practice, Discussion, Interview - Stakeholder
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Emory University
Stunting, Undernutrition
Bangladesh MSNP: Social Protection Mixed Methods Study
Despite progress in reducing high levels of undernutrition in Bangladesh, gaps in progress persist. They are particularly acute between rural and urban areas, and between the lowest wealth quintile and highest.
- Trial name
- NCT04166370
- Testing
- Control, Strengthened (Services and SBCC), Strengthened (Services and SBCC) + CCT
- Where
- Bangladesh
- Volunteers
- healthy volunteers welcome
- Sponsor
- FHI 360
Physical Activity
Moderate Aerobic Activity Through Yoga
The 2018 Physical Activity Guidelines for Americans (PAGA) recommend 150 minutes of moderate intensity activity for adult (18 years and older) Americans to promote health.
- Trial name
- MAT (NCT05184673)
- Testing
- Behavioral and environmental
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Polypharmacy, Deprescriptions
Deprescribing: a Portrait and Out-comes of the Reduction of Polypharmacy in Portugal
This study protocol comprises three phases. The first two phases will be nationwide and aim to evaluate the prevalence and patterns of polypharmacy and assess the barriers and facilitators of deprescribing perceived by older…
- Trial name
- DePil17-20 (NCT03283735)
- Testing
- Elderly Enablement
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- University of Beira Interior
Bone Diseases, Communication
Evaluation of Alerts in Promoting Bone Densitometry Scans
The purpose of this study is to assess, prospectively, the effect of provider-facing alerts for bone densitometry scans with and without a single-click best practice alert (BPA) on scan orders and completions.
- Trial name
- NCT04955652
- Testing
- Health Maintenance Topic, Actionable Sidebar Item, Best Practice Alert
- Volunteers
- healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Premature Birth
2-Brain Regulation to Achieve Improved Neuroprotection During Early Development
Each year 15 million infants are born preterm (PT). Even without severe comorbidities, they are exposed to sensory stress during the Neonatal Intensive Care Unit (NICU) stay and are at greater risk of neurodevelopmental problems…
- Trial name
- 2-BRAINED (NCT06659809)
- Testing
- Tele-care video-feedback intervention (TVFI)
- Where
- 2 sites in Italy
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Pulmonary Embolism, Deep Vein Thrombosis
Non-Interruptive Alerts for Improving Use of Clinical Decision Rules
This study is an extension of a planned quality improvement project that aims to promote standard of care by increasing the use of evidence-based clinical decision rules amongst emergency medicine providers in the University of…
- Conditions
- Pulmonary Embolism, Deep Vein Thrombosis, Minor Head Injury, Chest Pain
- Trial name
- NCT04702308
- Testing
- Clinical Decision Rule Alerts
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Utah
Lung Cancer Screening
Lung Cancer Screening Protocol
The successful implementation of lung cancer screening across diverse setting requires working with the community and primary care practices.
- Trial name
- I-STEP (NCT03958253)
- Testing
- Toolbox for Lung Cancer Screening
- Where
- 7 sites in United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Adherence to a Personalised Nutrition Programme
Exploring the Use of Genetic and Behavioural Data in Tailoring Dietary and Lifestyle Support
Personalised nutrition approaches typically rely on static information such as health status, lifestyle and genetic data. However, adherence often remains low because daily behaviours are influenced by psychological states…
- Trial name
- NCT07407556
- Testing
- Psychology-tailored message, Neutral message
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alexandra King
Pancreatic Diseases, Pancreatic Neoplasms
POstopeRative Standardization of Care: THe Implementation of Best Practice After Pancreatic Resection
This Nationwide stepped-wedge cluster randomized trial is designed to evaluate if the implementation of a best practice algorithm for postoperative care results in a decrease in incidence of major complications and death after…
- Conditions
- Pancreatic Diseases, Pancreatic Neoplasms, Pancreatic Cancer, Pancreatitis
- Trial name
- PORSCH (NCT03400280)
- Testing
- Best practice algorithm for postoperative care
- Where
- 17 sites in Netherlands
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- St. Antonius Hospital
Neck Pain, Headache
Prevention and Intervention of Neck Pain in Swiss Office-Workers
This study is the first that investigates the impact of a multi-component intervention combining current evidence of effective interventions with an adherence app to assess the potential benefits on productivity, neck pain, and…
- Conditions
- Neck Pain, Headache, Musculoskeletal Diseases, Adherence, Patient
- Trial name
- NEXpro (NCT04169646)
- Testing
- Multi-component intervention, Control
- Where
- 2 sites in Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Zurich University of Applied Sciences
Multiple Sclerosis (MS), Fatigue
Increasing Physical Activity for Adults With Multiple Sclerosis (MS)
This study aims to advance the scientific understanding and potential future implementation of physical activity promotion by testing the efficacy of a phone-based app for increasing activity in insufficiently active patients…
- Conditions
- Multiple Sclerosis (MS), Fatigue, Physical Inactivity
- Trial name
- NCT06270641
- Testing
- ExerciseRx intervention
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Washington