Clinical trials: Blood sampling
Obstetric Anesthesia Problems
Evaluation of the Level of Oxidative Stress in Relation to the Type of Anesthesia in Parturients Whose Delivery Was Completed by Caesarean Section
The goal of this observational study is to assess the level of oxidative stress during cesarean section depending on the type of anesthesia applied and to determine the factors that can affect the level of oxidative stress.
- Trial name
- NCT05973435
- Testing
- Blood sampling
- Where
- Serbia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Clinic Dr Dragisa Misovic-Dedinje
Myocardial Blood Flow Reserve, Mechanical Dyssynchrony
Mechanical Dyssynchrony and Microvascular Dysfunction by SPECT
The project is aimed at studying the feasibility of mechanical dyssynchrony of the left ventricle of the heart, determined by SPECT (gated MPI), as well as its stress-induced dynamics, in the evaluation of patients with coronary…
- Conditions
- Myocardial Blood Flow Reserve, Mechanical Dyssynchrony, Coronary Arterial Disease (CAD)
- Trial name
- MD&MD (NCT06969547)
- Testing
- dynamic SPECT (two-day rest/stress protocol), gated myocardial perfusion imaging, blood sampling
- Where
- Russia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Hepatocellular Carcinoma (HCC)
Annexin A2 as a Novel Diagnostic Marker in Hepatocellular Carcinoma
This study aimed to investigate the clinical utility of Annexin A2 serum level as a novel diagnostic marker of hepatocellular carcinoma (HCC) and to correlate its level with alpha fetoprotein the current marker ofhepatocellular…
- Trial name
- NCT02541149
- Testing
- blood sample
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Healthy Controls
Measuring the Healthy Pediatric Inflammatory Response to Vaccination.
The purpose of this research is to understand the normal healthy response to immunological challenge by measuring circulating cytokine and chemokine levels before and after vaccinations in healthy children.
- Trial name
- NCT04112355
- Testing
- Blood Collection
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Physical Fitness, Hormonal Response
Effects of Powerlifting-Based Training in Athletes
This randomized controlled trial aims to examine the effects of a weightlifting-based training program on hormonal, metabolic, and lipid profile parameters in athletes.
- Conditions
- Physical Fitness, Hormonal Response, Metabolic Parameters
- Trial name
- PLBT-ATH (NCT07398248)
- Testing
- Powerlifting-Based Training, Usual Basketball Training, Blood Sampling and Laboratory Analysis
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ramazan Erdoğan
Acute Lymphatic Leukemia, Lymphoma
More Than Just X-Rays - Imaging of Chemotherapy-induced Morphological and Functional Cardiovascular and Lung Changes After Childhood ALL and Other Cancers - a Monocentric Late Effects Study (MaximALL)
In this study, we investigate the cardiopulmonary health of survivors who underwent cancer treatment for acute lymphoblastic leukemia (ALL) or lymphoma during childhood, compared with healthy controls.
- Trial name
- MaximALL (NCT07705178)
- Testing
- QOL assessment, Neuropsychological, Spirometry, DLCO measurement
- Where
- Germany
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Embolic Stroke of Undetermined Source
Identification of New Markers of Atrial Myopathy in Patients With Embolic Stroke of Undetermined Source (ESUS) From MRI 4D Data
Atrial myopathy is considered to be the underlying cause of a large proportion of embolic strokes of undetermined source. However, the definition of this atrial condition is not well delineated while its identification could lead…
- Trial name
- IRM 4D-AVC (NCT04717843)
- Testing
- 4D Flow MRI, Medical consultation with 12 leads ECG, Holter ECG
- Where
- 3 sites in France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Gene Expression, Metabolomics
Gene Expression Monitoring of Mononuclear Cells (MNC) Subpopulations and Immunological Status and Metabolome Defining of Healthy Population
Study on healthy volunteers is focusing on analysis of transcriptome profile fluctuations in healthy population in three mononuclear cell types (CD4+ cells, CD56+ cells and CD4+CD25+ cells)and should provide a reference for…
- Conditions
- Gene Expression, Metabolomics, Immunological Status
- Trial name
- NCT01052649
- Testing
- Blood sampling
- Where
- Slovenia
- Volunteers
- healthy volunteers welcome
- Sponsor
- Blood Transfusion Centre of Slovenia
Essential Hypertension, Cardiovascular Disease
Prognostic Value of the Circadian Pattern of Ambulatory Blood Pressure for Multiple Risk Assessment
The HYGIA study was designed to investigate prospectively 1. the prognostic value of ambulatory blood pressure (BP) monitoring among subjects primarily evaluated at primary care settings 2.
- Conditions
- Essential Hypertension, Cardiovascular Disease, Stroke, Chronic Kidney Disease
- Trial name
- HYGIA (NCT00741585)
- Testing
- Any antihypertensive medication alone or in combination, Ambulatory blood pressure monitoring
- Where
- 20 sites in Spain
- Volunteers
- 21,983 people, healthy volunteers welcome
- Sponsor
- University of Vigo
Major Depressive Disorder, Post-Traumatic Stress Disorder
Imaging SV2A in Mood Disorders
This study is designed to examine SV2A density in MDD and PTSD as a correlate of synaptic density, and to determine whether ketamine administration will reverse the synaptic loss in vivo in human subjects.
- Trial name
- NCT02734602
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Yale University
Healthy Volunteers
A Study of the Effect of Epinephrine on Platelet Reactivity in Subjects Treated With Ticagrelor
The study is an experimental observational study in ten healthy volunteers. Based on an in vitro study, it is hypothesize that a low dose epinephrine infusion will improve platelet function in healthy volunteers who have received…
- Trial name
- NCT03441412
- Testing
- Ticagrelor 90mg, Epinephrine, Metoprolol
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Ketosis
Variations in Ketone Metabolism
This outcome of this study will elucidate how the phenotype of the individual modulates the KE metabolic effect. Most studies of KE have been in homogenous populations, usually young, male athletes.
- Trial name
- STAK-VKM (NCT05924295)
- Testing
- Ketone Supplement, Beverage Tolerability Questionnaire (BTQ) and satiety visual analogue scale, Blood Draw
- Where
- 2 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Virus Diseases
A Study to Evaluate Persistence of Immune Responses After Post-exposure Prophylaxis of Rabipur® (Purified Chicken-embryo Cell Rabies Vaccine) in Chinese Children
The purpose of this study is to evaluate the long-term persistence of immune responses approximately 5 years or more after simulated rabies post-exposure prophylaxis provided in 2012 according to Essen (1-1-1-1-1) or Zagreb…
- Trial name
- NCT02991872
- Testing
- Blood draw
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Obesity
Genomic Search for Childhood Obesity Genes-A Pilot Study
The purpose of this study is to screen a pediatric population (ages 2-8) for genes associated with childhood obesity.
- Trial name
- NCT00484172
- Testing
- blood draws
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Pain
Effect on Pain of Oral Sucrose Versus Placebo in Children 1 to 3 Months Old Needing Venipuncture
Background : Previous studies suggest that early recognition and treatment of pain among children is important for their cognitive development and their future response to pain throughout their life.
- Trial name
- NCT01293812
- Testing
- 88% sucrose po solution
- Where
- Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Cancer
Heparin Versus Normal Saline in Peripherally Inserted Central Catheter Lines
The study team will be performing a study comparing the use of Heparin Flushes vs. Normal Saline Flushes in making sure central lines stay open.
- Trial name
- NCT05029596
- Testing
- Normal Saline Group, Heparin Group
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Cardiovascular Diseases
Heartmatters Challenge - First Responders
The purpose of this protocol is to observe whether providing the first responder population with a multi-tiered therapeutic lifestyle modification program, including regular blood testing, diet and telephonic lifestyle coaching…
- Trial name
- HMC-FR (NCT03322046)
- Testing
- Lifestyle Program
- Where
- United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Boston Heart Diagnostics
Vitamin B12 Deficiency, Folic Acid Deficiency
The Association Between Religious Origin and Age, and Vitamin B12 and Folic Acid Plasma Levels in Non Jewish Population in Western Galilee
Vitamin B12 deficiency is more widespread in the population than has been assumed so far. Since a deficiency in this vitamin can lead to irreversible neurological damage, early diagnosis is essential.
- Trial name
- NCT01297361
- Testing
- Blood Sample
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
HIV Infections
PK of Once Daily ART Containing Tenofovir and Atazanavir/Ritonavir
The purpose of this project is to study the pharmacokinetics of a once-daily antiretroviral medication used to treat adolescents and young adults with HIV infection.
- Trial name
- NCT00273273
- Testing
- blood draw
- Where
- 12 sites in United States, Puerto Rico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Tako-tsubo Cardiomyopathy
Pathogenesis of Acute Stress Induced (Tako-tsubo) Cardiomyopathy: Energy Shut-Down or Intense Inflammation?
Tako Tsubo Cardiomyopathy (TTC), also known as "Broken Heart Syndrome", is a disorder of the heart that occurs most commonly in women (although it occasionally occurs in men) and is usually related to a stressful event.
- Trial name
- TERRIFIC (NCT02897739)
- Testing
- Magnetic resonance imaging, Acute Inflammatory Activation study, PET CT
- Where
- United Kingdom
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
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