Clinical trials: Remifentanil
Rhinosinusitis Chronic, Sinus Cancer
TIVA vs TXA in Sinus Surgery to Evaluate Operative Blood Loss and Surgical Field Quality
The goal of this interventional study is to compare the efficacy (surgical field quality and intra-operative blood loss) or cost of TIVA alone to general inhalational anesthetics with intravenous TXA in patient participants who…
- Conditions
- Rhinosinusitis Chronic, Sinus Cancer, Sinus Polyp, Encephalocele
- Trial name
- NCT05639686
- Testing
- Tranexamic acid injection, Total Intravenous Anesthesia, Inhalational isoflurane
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Our Lady of the Lake Hospital
Cholecystolithiasis
Closed-Loop Target Controlled Infusion in Laparoscopic Cholecystectomy
Laparoscopic Cholecystectomy applied to Artificial pneumoperitoneum and the extent of Surgical stimulation cause the wave of hemodynamics increase vigorously, which make it difficult to judge the depth of anesthesia according to…
- Trial name
- CLTCI (NCT02114437)
- Testing
- Closed-loop TCI, Opened-loop TCI
- Where
- China
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Anesthesia,General, Cardiac Event
Hemodynamic Parameters and Cardiac Enzyme Levels in Patients Undergoing General Anesthesia
The goal of this observational study is to learn about the effects of total intravenous general anesthesia with target controlled infusion and sevoflurane based balanced general anesthesia on hemodynamic parameters and cardiac…
- Trial name
- NCT05598567
- Testing
- target controlled infusion - total intravenous general anesthesia, sevoflurane based balanced general anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Duzce University
Pain, Acute, Analgesia
Preanesthetic Analgesia/Nociception Index (ANI) and Propofol Injection Pain
Recently, Analgesia Nociception Index (ANI) has been evaluated for objectively measuring peri-operative pain and to guide intra-operative opioid administration during various surgeries.
- Conditions
- Pain, Acute, Analgesia, Nociceptive Pain
- Trial name
- NCT05049577
- Testing
- Analgesia/Nociception Index (ANI)
- Where
- South Korea
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Laparoscopic Hysterectomy, Magnesium Sulfate
Intravenous Administration of Magnesium Sulfate in Laparoscopic Hysterectomy Cases
In our study, it was aimed to show the contribution of intraoperative intravenous magnesium sulfate administration to peroperative opioid consumption and postoperative analgesia.
- Conditions
- Laparoscopic Hysterectomy, Magnesium Sulfate, General Anesthesia
- Trial name
- MgSO4 (NCT05826119)
- Testing
- magnesium sulfate group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Hypotension Drug-Induced, Cerebral Oxygen Saturation
Effect of Controlled Hypotension on Cerebral Oxygen Saturation
For a successful functional endoscopic sinus surgery (FESS), it is crucial to provide effective controlled hypotension to reduce blood loss and provide a relatively blood-free surgical environment to facilitate surgery.
- Trial name
- NCT02967029
- Testing
- Esmolol Hydrochloride, Remifentanil Hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Ureterorenoscopic Lithotripsy, Transurethral Resection of the Bladder
Inhalational Agents Versus Dexmedetomidine for Maintenance of General Anesthesia
The climate crisis and environmental pollution are escalating day by day, making the reduction of carbon footprints increasingly important both on an individual and industrial level.
- Conditions
- Ureterorenoscopic Lithotripsy, Transurethral Resection of the Bladder, Percutaneous Nephrolithotomy, Transurethral Resection of the Prostate
- Trial name
- NCT07363681
- Testing
- Dexmedetomidine + Remifentanil, Desflurane + Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Sleep Disorder, Sleep, Inadequate
Measuring Sleep Quality In Patients That Posterior Spinal Instrumentatıon Plannıng
Postoperative sleep disorders have serious problems with cognition, pain perception, sustained circadian rhythm, psychomotor function, metabolic function, catabolic responses, and continuity.
- Conditions
- Sleep Disorder, Sleep, Inadequate, Total ıntravenous Anesthesia, Inhalation Anesthesia
- Trial name
- NCT06269328
- Testing
- Total ıntravenous anesthesia with propofol and remifentanil for anesthetic maintenance, Inhalation anesthesia with sevoflurane for anesthetic maintenance
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Uludag University
Inhalation Anesthesia, Lung Injury
The Effect of Sevoflurane and Desflurane on Clara Cell Protein on the Lung
Inhalation anesthesia; It means that the anesthetic drugs taken by the respiratory tract pass into the blood through the lung alveoli, reach the brain tissue, and create an anesthetic effect according to the density in the brain…
- Trial name
- NCT04645316
- Testing
- Sevoflurane, Desflurane, Propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Inonu University
Rocuronium, Injection Pain
Median Effective Dose of Remifentanil for the Prevention of Pain Caused by the Injection of Rocuronium
As a medium-and long-term non-depolarizing muscle relaxant, rocuronium has the advantages of quick effect, no histamine release and accumulation and no obvious cardiovascular adverse reactions, so it has been widely used in…
- Trial name
- NCT05217238
- Testing
- Remifentanil
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Yangzhou University
Nasal Polyps
Comparison of Metoprolol and Tramadol With Remifentanil in Endoscopic Sinus Surgery
Functional endoscopic sinus surgery (FESS) is indicated in diseases such as chronic sinusitis refractory to medical treatment, nasal polyposis, mass lesions in the nasal cavity.
- Trial name
- NCT02484859
- Testing
- Remifentanil, Tramadol, Metoprolol
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Burn Unspecified Degree, Deep Sedation
Effects Of Different Anesthesia Applications On Mood, Depression, And Anxiety Levels In Burn Patients
Adequate and effective pain management and prevention of depression are essential in burn patients. This study aims to investigate the effects of ketamine sedation in burn patients in terms of mood disorders, depression, anxiety…
- Trial name
- NCT06165848
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- T.C. Sağlık Bakanlığı Ankara Bilkent Şehir Hastanesi
Delirium, Anesthesia
Incidence of Postoperative Delirium in Cancer Patients After Laparoscopic Surgery in Trendelenburg Position
Postoperative delirium is an acute mental syndrome that is caused by diffuse cerebral dysfunction resulting from the action of predisposing and precipitating factors acting together.
- Trial name
- NCT03572517
- Testing
- Subarachnoid block, Spinal morphine
- Where
- Brazil
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- AC Camargo Cancer Center
Prostate Cancer
A Comparison of Totally Intravenous and Inhalation Anesthesia for Intraocular Pressure During Robot-Assisted Laparoscopic Radical Prostatectomy
Robot-assisted laparoscopic radical prostatectomy (RALRP) has gained popularity during the past decade and has widely replaced conventional open prostatectomy in many institutions due to reduced blood loss, nerve sparing, less…
- Trial name
- NCT01744262
- Testing
- Total intravenous anesthesia, Inhalation Anesthesia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Complication of Labor and/or Delivery
Efficacy and Satisfaction With Remifentanil Analgesia in Parturients During the Childbirth
Retrospective observational study to determine the efficacy of remifentanil during the delivery. Authors will search the data in period between 2010 and 2014 in cohort of 100 parturients and obtain data of analgesic efficacy (VAS…
- Trial name
- NCT02447757
- Testing
- remifentanil
- Where
- 2 sites in Czechia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Brno University Hospital
Anesthesia
Improving Information Extraction From EEG on Cerebral Anesthetic Drug Effects
This is an interventional, randomized controlled study in health volunteers that involves collecting data on raw EEG waves measuring various combinations of anesthetic drugs during standardized drug titration.
- Trial name
- NCT02043938
- Testing
- SedLine EEG sensor
- Where
- Netherlands
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Opioid Induced Swallowing Disorders
Opioid Induced Swallowing Difficulties and Risk for Pulmonary Aspiration
The purpose of this study is to determine weather remifentanil induced swallowing difficulties increase risk for pulmonary aspiration.
- Trial name
- NCT01495377
- Testing
- Remifentanil, Technetium, Dynamometer (Jamar)
- Where
- 2 sites in Sweden
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
General Anesthetics Toxicity
Anesthetic Neurotoxicity: the Association Between General Anesthesia and the Level of Plasma Neurofilament Light
A prospective controlled single centre study designed to determine the association between the exposure to anesthetic agents and the pre and postoperative changes in plasma Neurofilament Light levels, biomarkers of neurological…
- Trial name
- ANESTOX-2019 (NCT04164329)
- Testing
- General anesthetic
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cardiocentro Ticino
Thyroid Surgeries, Intraoperative Analgesic Use
qCON/qNOX-Guided Anesthesia in Patients Undergoing Thyroidectomy Surgery
The aim of this study is to evaluate the effect of using the non-invasive Conox monitor on intraoperative opioid consumption. Additionally, the study aims to assess the impact of Conox monitoring on recovery time, postoperative…
- Conditions
- Thyroid Surgeries, Intraoperative Analgesic Use, Anesthesia Depth Monitoring
- Trial name
- NCT07445659
- Testing
- Connox EEG Monitoring, standard anesthesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kayseri City Hospital
Myocardial Injury After Non-cardiac Surgery, Hypotension During Surgery
The Effects of General Versus Spinal Anesthesia on Postoperative Myocardial Injury
In this prospective, randomized, single-blind study, we aim to compare the effects of general anesthesia and spinal anesthesia on postoperative myocardial injury in elderly patients undergoing hip surgery.
- Conditions
- Myocardial Injury After Non-cardiac Surgery, Hypotension During Surgery, Anesthesia, General, Anesthesia, Spinal
- Trial name
- NCT06343259
- Testing
- General Anesthesia, Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital